Search results for "absorption."

showing 10 items of 2682 documents

Lipodepsipeptides from Pseudomonas syringae are partially proteolyzed and are not absorbed by humans: An in vitro study

2008

There are some concerns about the use of Pseudomonas-based products as biocontrol agents because of the hemolytic activity shown by their metabolites. The effects of Pseudomonas lipodepsipeptides (LDPs) on mammals via ingestion and the LDP degradation during the digestion and intestinal permeability have not been evaluated. In this research, the susceptibility of different LDPs to degradation was assayed with enzymatic gastrointestinal digestion, and intestinal permeability to LDPs was investigated in an in vitro system based on an intestinal cell layer system. Results demonstrated that trypsin and chymotrypsin hydrolyze up to 50% of the various LDPs, and that proteolysis was further increa…

lipodepsipeptidesProteolysisPseudomonas syringaelipodepsipeptides; Pseudomonas syringae; enzymatic digestionPronaseIn Vitro TechniquesPeptides CyclicRisk AssessmentMicrobiologyMicrobiologyenzymatic digestionmedicinePseudomonas syringaeHumansLife SciencePest Control BiologicalIntestinal permeabilitybiologymedicine.diagnostic_testPseudomonasbiology.organism_classificationTrypsinmedicine.diseaseIntestinal AbsorptionBiochemistryConsumer Product SafetyDigestionDigestionFood Sciencemedicine.drugPseudomonadaceaeJournal of Food Protection
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Glycerosomes:investigation of role of 1,2-dimyristoyl-sn-glycero-3-phosphatidycholine (DMPC) on the assembling and skin delivery performances

2017

Glycerosomes were formulated using 1,2-dimyristoyl-sn-glycero-3-phosphatidycholine (DMPC), diclofenac sodium salt and 10, 20 or 30% glycerol in the water phase, while corresponding liposomes were prepared with the same amount of DMPC and diclofenac, without glycerol. The aim of the present work was to evaluate the effect of the used phospholipid on vesicle features and ability to favour diclofenac skin deposition by comparing these results with those found in previous works performed using hydrogenated soy phosphatidylcholine (P90H) and dipalmitoylphosphatidylcholine (DPPC). Liposomes and glycerosomes were multilamellar, liposomes being smaller (72±6nm). Interactions among glycerol, phospho…

liposomes3003skindimyristoylphosphatidylcholinePhospholipidPharmaceutical Science02 engineering and technologyrehological studies010402 general chemistry01 natural sciencesDSCchemistry.chemical_compoundglycerosomesdrug delivery systemsPhosphatidylcholineGlycerolskin deliveryDSC; glycerosomes; rehological studies; SAXS; skin delivery; animals; diclofenac; dimyristoylphosphatidylcholine; liposomes; skin; swine; drug delivery systems; skin absorption; 3003LiposomeChromatographyBilayerVesicletechnology industry and agricultureswineDiclofenac SodiumSAXS021001 nanoscience & nanotechnologyskin absorption0104 chemical sciencesanimalsdiclofenacchemistryDipalmitoylphosphatidylcholinelipids (amino acids peptides and proteins)0210 nano-technology
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Phosphatidylcholine liposomes as carriers to improve topical ascorbic acid treatment of skin disorders

2015

Gabriel Serrano,1,* Patricia Almudéver,2,* Juan-Manuel Serrano,1 Javier Milara,2–5 Ana Torrens,1 Inmaculada Expósito,1 Julio Cortijo2–51Sesderma Laboratorios, 2Department of Pharmacology, Faculty of Medicine, University of Valencia, 3Clinical Research Unit, University General Hospital Consortium, 4CIBERES, Health Institute Carlos III, 5Research Foundation of the University General Hospital of Valencia, Valencia, Spain*These authors contributed equally to this workAbstract: Liposomes have been intensively investigated as carriers for different applications in dermatology and cosmetics. Ascorbic acid has potent antioxidant and anti-inflammatory proper…

liposomesSodium ascorbateLiposomefluoresceinintegumentary systembusiness.industryHuman skinDermatologyAscorbic acidskin absorptionchemistry.chemical_compoundmedicine.anatomical_structureClinical Cosmetic and Investigational DermatologyDermischemistryPhosphatidylcholineImmunologyBiophysicsStratum corneumMedicineFluoresceinbusinessphosphatidylcholinesodium ascorbateOriginal ResearchClinical, Cosmetic and Investigational Dermatology
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Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses

2019

The present work aimed to explain the differences in oral performance in fasted humans who were categorized into groups based on the three different drug product formulations of dexketoprofen trometamol (DKT) salt&mdash

liquid–liquid phase separationSALT DISPROPORTIONATIONgastrointestinal absorptionSodiumlcsh:RS1-441Pharmaceutical ScienceExcipientchemistry.chemical_elementSalt (chemistry)Hydrochloric acidSOLUBILITYCalciumBioequivalenceArticlelcsh:Pharmacy and materia medicachemistry.chemical_compoundFLUIDSEMAoral absorptionABSORPTIONmedicinePharmacology & PharmacySUPERSATURATED SOLUTIONSdexketoprofenSimulationchemistry.chemical_classificationScience & TechnologyChemistryliquid-liquid phase separationPhosphateDexketoprofenSIMILARITIESgastrointestinal simulatorin vitro dissolutionIN-VITRO DISSOLUTIONLife Sciences & BiomedicineVIVO DISSOLUTIONMETHODOLOGYmicroscopy imagingmedicine.drugPharmaceutics
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ODS tērauda izejmateriālu lokālās struktūras analīze izmantojot Ti un Y K-malas rentgenabsorbcijas spektroskopiju

2017

Šajā darbā tika izmantota rentgenstaru absorbcijas spektru analīze oksīdu stiprinātam tēraudam (ODS), kas ir perspektīvs materiāls dažādās jomās, piemēram, saules elektrostacijās, reaktīvos dzinējos, ķīmiskos reaktoros un kodolreaktoros, jo materiālam piemīt tādas īpašības kā laba siltumvadītspēja un zema termiskās izplešanās apvienojumā ar augstu temperatūras izturību, korozijas un radiācijas pretestību. Darbā tiek iegūta informācija par ar dažādām metodēm izgatavotu ODS tēraudu lokālās atomārās struktūras izmaiņu ap itrija (Y) un titāna (Ti) atomiem, analizējot Y un Ti absorbcijas K-malu.

local atomic structureODS steelsFizikax-ray absorption spectroscopymechanical alloyingSTARS
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ODS tērauda izejmateriālu lokālās struktūras analīze, izmantojot rentgenabsorbcijas spektroskopiju

2015

Oksīdu stiprināts tērauds (ODS) ir perspektīvs kodolsintēzes reaktoru materiāls, kuram ir lieliska siltumvadītspēja un zema termiskās izplešanās, apvienojumā ar augstu temperatūras izturību, korozijas un radiācijas pretestību. Tamdēļ šo materiālu var izmantot arī daudzos citos pielietojumos, piemēram, saules elektrostacijās, reaktīvos dzinējos, ķīmiskos reaktoros, kā arī ūdeņraža ražošanā. Šajā darbā ar rentgenabsorbcijas spektroskopijas metodi tika analizētas ferīta un austentisko ODS tēraudu lokālās atomārās struktūras izmaiņas ap dzelzs (Fe) un hroma (Cr) atomiem dažādos tēraudu izgatavošanas posmos, analizējot Fe un Cr absorbcijas K-malas spektrus.

local atomic structurerentgenabsorbcijas spektroskopijalokālā atomārā struktūraODS tēraudsFizikax-ray absorption spectroscopy
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When the Grafting of Double Decker Phthalocyanines on Si(100)-2 × 1 Partly Affects the Molecular Electronic Structure

2016

International audience; A combined X-ray photoelectron spectroscopy (XPS), scanning tunneling microscopy (STM), and density functional theory (DFT) study has been performed to characterize the adsorbate interaction of lutetium biphthalocyanine (LuPc2) molecules on the Si(100)-2 × 1 surface. Large molecule–substrate adsorption energies are computed and are found to compete with the molecule–molecule interactions of the double decker molecules. A particularly good matching between STM images and computed ones confirms the deformation of the molecule upon the absorption process. The comparison between DFT calculations and XP spectra reveals that the electronic distribution in the two plateaus …

lutetium bi-phthalocyanineSiliconXASAtom and Molecular Physics and OpticsSTMAnalytical chemistrychemistry.chemical_element02 engineering and technology010402 general chemistryDFT[ CHIM ] Chemical Sciences01 natural sciencesSi(100)law.inventionAdsorptionX-ray photoelectron spectroscopyscanning tunneling microscopelawbasis-setXPS[CHIM]Chemical SciencessurfaceMoleculePhysical and Theoretical ChemistryBasis setmetal-free phthalocyaninefield-effect transistorsPhthalocyaninebis-phthalocyanine021001 nanoscience & nanotechnology0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialstotal-energy calculationsGeneral EnergyElectronic Structurechemistrysi(001)Chemical physicsthin-filmsaugmented-wave methodAtom- och molekylfysik och optikDensity functional theoryScanning tunneling microscopeAbsorption (chemistry)0210 nano-technologyThe Journal of Physical Chemistry C
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Why do we enjoy creative tasks? Results from a multigroup randomized controlled study

2016

Previous studies have linked positive emotions with creativity, but it remains unknown why creative activities may enhance positive emotions. We tested how creative tasks influence autonomous self-expression and task absorption, and whether this in turn increases positive emotions. Data from 478 participants were divided into four language samples (English, German, Italian, and Polish) and analyzed in a series of multigroup structural equation models. The indirect effects were replicated in all samples. Creative tasks enhanced positive emotions through an increase in autonomy. However, participants who solved creative tasks also reported lower task absorption, and this has hindered their ex…

media_common.quotation_subject05 social sciences050109 social psychologyAbsorption (psychology)CreativityStructural equation modelinglanguage.human_languageEducationlaw.inventionTask (project management)GermanRandomized controlled triallaw0502 economics and businesslanguage0501 psychology and cognitive sciencesPsychologyDivergent thinkingSocial psychology050203 business & managementAutonomymedia_commonCognitive psychologyThinking Skills and Creativity
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Zein as biodegradable material for effective delivery of alkaline phosphatase and substrates in biokits and biosensors

2016

A biodegradable material, zein, is proposed as a reagent delivery platform for biokits and biosensors based on alkaline phosphatase (ALP) activity/inhibition in the presence of phosphatase substrates. The immobilization and release of both the substrate and/or the active ALP, in a biodegradable and low-cost material such as zein, a prolamin from maize, and in combination with glycerol as plasticizer have been investigated. Three zein-based devices are proposed for several applications: (1) inorganic phosphorus estimation in water of different sources (river, lake, coastal water and tap water) with a detection limit of 0.2mg/L - compared to at least 1mg/L required by legislation, (2) estimat…

media_common.quotation_subjectZeinBiomedical EngineeringBiophysicsBiocompatible Materials02 engineering and technologyBiosensing Techniques01 natural sciencesPlasticizersGratitudeAbsorbable ImplantsAlkaline phosphataseElectrochemistrySalivamedia_commonChemistry010401 analytical chemistryfood and beveragesPhosphorusGeneral MedicineEquipment Design021001 nanoscience & nanotechnologyBiomaterial0104 chemical sciencesEquipment Failure AnalysisPesticideSpectrometry FluorescenceBiosensorsBiochemistryAbsorption PhysicochemicalAlkaline phosphataseColorimetryReagent Kits Diagnostic0210 nano-technologyBiotechnology
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Data from: Primary production calculations for sea ice from bio-optical observations in the Baltic Sea

2017

Bio-optics is a powerful approach for estimating photosynthesis rates, but has seldom been applied to sea ice, where measuring photosynthesis is a challenge. We measured absorption coefficients of chromophoric dissolved organic matter (CDOM), algae, and non-algal particles along with solar radiation, albedo and transmittance at four sea-ice stations in the Gulf of Finland, Baltic Sea. This unique compilation of optical and biological data for Baltic Sea ice was used to build a radiative transfer model describing the light field and the light absorption by algae in 1-cm increments. The maximum quantum yields and photoadaptation of photosynthesis were determined from 14C-incorporation in phot…

medicine and health carePrimary productionLife SciencesMedicineCDOMabsorptionsea iceparticle absorption
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