Search results for "active"
showing 10 items of 5361 documents
Pain reduction by dehydrated human amnion/chorion membrane allograft in nondiabetic leg ulcers might be an early indicator of good response: A case s…
2020
Dehydrated human amnion/chorion membrane allograft (dHACM) derived from placenta is increasingly used for skin and soft tissue repair in several medical specialties. Promising effects of dHACM were also reported in chronic venous and diabetic leg ulcers. However, dHACM is cost-intensive and its effect on chronic leg ulcers of other etiologies and pain reduction is unknown. Clinical predictors of a favorable response to dHACM during the early treatment period could help to limit unnecessary costs. In our case series with six patients suffering from chronic lower leg ulcers of various etiology, the effect of dHACM once per week on reduction of pain and wound size during a 5-week period was ex…
Music and Emotions in the Brain: Familiarity Matters
2011
The importance of music in our daily life has given rise to an increased number of studies addressing the brain regions involved in its appreciation. Some of these studies controlled only for the familiarity of the stimuli, while others relied on pleasantness ratings, and others still on musical preferences. With a listening test and a functional magnetic resonance imaging (fMRI) experiment, we wished to clarify the role of familiarity in the brain correlates of music appreciation by controlling, in the same study, for both familiarity and musical preferences. First, we conducted a listening test, in which participants rated the familiarity and liking of song excerpts from the pop/rock repe…
The dependence of circular dichroism in photoemission on the optical properties of Cs monolayers on Pt(111)
1997
We report on the dependence of dichroic photoemission excited by circularly polarised light on the angle of photon incidence. We measured the difference in the angle-resolved photoemission intensities from Cs 5p semi-core levels excited by photons of opposite helicity, which is known as CDAD. We found that the dependence of the measured differences on the angle of light incidence deviates strongly from the model of CDAD for free atoms, as expected. Using the Fresnel equations and a complex index of refraction, one finds that not only the third component but also the second component of the Stokes vector is responsible for the excitation process. Both Stokes components change sign if the ini…
Size-exclusion high-performance liquid chromatography in the study of the autoassociating antibiotic gramicidin A in micellar milieu.
2003
Gramicidin A (gA) is a polypeptide antibiotic which forms dimeric channels specific for monovalent cations in biological membranes. It is a polymorphic molecule that adopts several different conformations, double-stranded (ds) helical dimers (pore conformation) and single-stranded beta-helical dimers (channel conformation). This study investigated the conformational adaptability of gramicidin A when incorporated into micelles as membrane-mimetic model system. Taking advantage of our reported, versatile, size-exclusion high-performance liquid chromatography (SE-HPLC) strategy that allows the separation of double-stranded dimers and monomers, we have quantitatively characterized the conformat…
Two Latent and Two Hyperstable Polymeric Forms of Human Neuroserpin
2010
AbstractHuman neuroserpin (hNS) is a serine protease inhibitor that belongs to the serpin superfamily and is expressed in nervous tissues. The serpin fold is generally characterized by a long exposed loop, termed the reactive center loop, that acts as bait for the target protease. Intramolecular insertion of the reactive center loop into the main serpin β-sheet leads to the serpin latent form. As with other known serpins, hNS pathological mutants have been shown to accumulate as polymers composed of quasi-native protein molecules. Although hNS polymerization has been intensely studied, a general agreement about serpin polymer organization is still lacking. Here we report a biophysical chara…
Ein optisch aktives Polyamid mit atropisomeren Binaphthyl-Grundbausteinen
1968
Zur Darstellung eines optisch aktiven Polyamids mit atropisomeren Grundbausteinen in der Hauptkette wurde (+)-2.2′-Diamino-binaphthyl-(1.1′) (II) hergestellt. Die Drehwerte in einigen Losungsmitteln sowie optische Rotationsdispersion (ORD), Circulardichroismus (CD) und UV-Spektrum werden angegeben. Durch Grenzflachenpolykondensation von II mit Terephthaloylchlorid wurde ein optisch aktives Polyamid (III) erhalten. Drehwerte, ORD und CD von III werden gemessen und mit denen des als Modellsubstanz dargestellten (+)-2.2′-Dibenzamido-binaphthyls-(1.1′) (IV) verglichen. Beide Substanzen zeigen mehrere COTTON-Effekte, die hinsichtlich ihres Vorzeichens ubereinstimmen. In ihrer Lage sind jedoch di…
Civil Society in the 2004 Romanian Elections: Watchdog, Involved Arbiter or Political Actor?
2010
Abstract Civil society has proven outstanding capacities of involvement in the 2004 general elections in Romania and put a remarkable pressure on the political society. This paper aims to discuss the consequences of such involvement for both the political and civil society. We also investigate the conditions that have favoured a successful challenge of the main political actors by the most visible civic advocacy organizations. Further, we inquire how deep can an actor from the civil society go into the lands of the political society. In the end, we weight the achievements and the failures of civil society’s active involvement in the game of elections.
Teaching and learning in consumer behavior: a class activity supporting real decision-making in cultural management
2010
Abstract Problem-based learning has been suggested as a useful tool to foster student-centered learning and increase student motivation. Students of Business Administration are not familiar with Research on Consumer Behavior, its contents and techniques, since this subject is traditionally linked to Psychology. In order to facilitate the teaching-learning process in this subject, this paper presents an application of problem-based learning in the context of Consumer Behavior. Results of this pilot experience are assessed under a qualitative and a quantitative basis. The evidence obtained allow us to conclude that this collaboration project enable students to obtain and to process informatio…
Some new fixed point results in non-Archimedean fuzzy metric spaces
2013
In this paper, we introduce the notions of fuzzy $(\alpha,\beta,\varphi)$-contractive mapping, fuzzy $\alpha$-$\phi$-$\psi$-contractive mapping and fuzzy $\alpha$-$\beta$-contractive mapping and establish some results of fixed point for this class of mappings in the setting of non-Archimedean fuzzy metric spaces. The results presented in this paper generalize and extend some recent results in fuzzy metric spaces. Also, some examples are given to support the usability of our results.
Canakinumab in Systemic Juvenile Idiopathic Arthritis: Clinical Inactive Disease Rate and Safety in Italian Patients
2020
Introduction: Systemic juvenile idiopathic arthritis (sJIA) accounts for 10-20% of all patients with JIA. The demonstration of a key role of IL-1 and IL-6 in the pathogenesis of the disease, led to consider sJIA an autoinflammatory disease: this explain the successfully use of IL-1 and IL-6 inhibitors. While the efficacy and safety of anakinra in sJIA is widely documented, there are no reports on large series of patients treated with canakinumab outside of the setting of clinical trials. Objectives: The aim of this study was to evaluate clinical response rate and disease course of canakinumab in Italian cohort of patients with sJIA. Methods: This is a retrospective multicenter study. Demogr…