Search results for "active"

showing 10 items of 5361 documents

Involvement of caspase-3 and GD3 ganglioside in ceramide-induced apoptosis in Farber disease.

2000

Farber's disease (FD) is a rare genetic disorder caused by ceramidase deficiency, which results in ceramide accumulation in lung, liver, colon, skeletal muscle, cartilage, and bone. Although this disease has been symptomatically characterized, little is known about its molecular pathogenetic process. Because recent studies reported that ceramide accumulation induces GD3 ganglioside formation and apoptosis, we investigated, in tissue obtained via colonoscopy from seriously involved patients, the possible involvement of ceramide in FD colonocyte destruction. Histochemical and TUNEL analyses of paraffin-embedded sections revealed that 45 ± 4.3% of FD colonocytes showed morphological signs of …

AdultCeramidePathologymedicine.medical_specialtyHistologyColonCaspase 3ApoptosisCeramideschemistry.chemical_compoundGangliosidesmedicineGD3 gangliosideHumansIntestinal MucosaCaspaseFarber diseaseFarber diseaseTUNEL assaybiologyCaspase 3ApoptosiCell Biologymedicine.diseaseCeramidaseCaspaseK18EpitheliumActive caspase-3Lysosomal Storage Diseasesmedicine.anatomical_structurechemistryApoptosisCaspasesCancer researchbiology.proteinAnatomyActive caspase-3; Apoptosis; Caspases; Farber disease; GD3 ganglioside; K18; Anatomy; Cell BiologyThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
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Nurses' self-reflection via videotaping to improve communication skills in health counseling.

1999

Abstract The purpose of this qualitative research was to describe nurses' opinions of their communication skills in health counseling situations and to analyze the levels of reflectivity in their evaluations according to Mezirow. Nineteen nurses participated in the research on a voluntary basis and evaluated their interaction with patients on video on two occasions half a year apart. Nurses gave verbal feedback in an interview immediately after videotaping, after which they read education materials, watched their counseling on video and wrote an evaluation of their communication skills. Transcribed audiotaped interviews and written evaluations were analyzed using content analysis. Nurses sa…

AdultCounselingMaleSelf-AssessmentAdolescentmedia_common.quotation_subjecteducationNursing Methodology ResearchNonverbal communicationNursingPatient Education as TopicMedicineHumansActive listeningmedia_commonAgedbusiness.industryCommunicationVideotape RecordingGeneral MedicineMiddle AgedFeelingContent analysisSelf-reflectionScale (social sciences)FemaleNursing StaffClinical CompetenceCommunication skillsbusinessNurse-Patient RelationsNeeds AssessmentQualitative researchPatient education and counseling
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Empowering counseling--a case study: nurse-patient encounter in a hospital

2001

This study illustrates practices that a nurse uses in order to empower patients. The emphasis is on speech formulae that encourage patients to discuss their concerns and to solicit information about impending surgery. The study is a part of a larger research project and a single case was selected for presentation in this article because it differed from the rest of the data by manifesting empowering practice. A videotaped nurse-patient health counseling session was conducted in a hospital and transcribed verbatim. The investigator interviewed the nurse and the patient after the conversation, and these interviews were transcribed as well. The encounter that is presented here as a case study …

AdultCounselingmedia_common.quotation_subjectPublic Health Environmental and Occupational HealthMEDLINEVideotape RecordingMiddle AgedSurgical proceduresNurse patientSession (web analytics)EducationPresentationNursingVerbal expressionSurgical Procedures OperativeHumansFemaleConversationActive listeningPower PsychologicalNurse-Patient RelationsPsychologymedia_commonHealth Education Research
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Learning to Cycle : A Cross-Cultural and Cross-Generational Comparison

2022

BackgroundLearning to cycle is an important milestone for children, but the popularity of cycling and the environmental factors that promote the development and practice of this foundational movement skill vary among cultures and across time. This present study aimed to investigate if country of residence and the generation in which a person was born influence the age at which people learn to cycle.MethodsData were collected through an online survey between November 2019 and December 2020. For this study, a total of 9,589 responses were obtained for adults (self-report) and children (parental report) living in 10 countries (Portugal, Italy, Brazil, Finland, Spain, Belgium, United Kingdom, M…

AdultCross-Cultural ComparisonParentscyclingoppiminenympäristötekijätcountryLCSocial Scienceslapset (ikäryhmät)sukupolvetasenteetliikuntakulttuurichildrenRA0421kulttuuriSurveys and QuestionnairesgenerationMedicine and Health SciencesHumansChildpyöräilymatkustaminenPublic Health Environmental and Occupational Healthactive travelSpainliikkuminencycling country generation active travel childrenBrazilfyysinen aktiivisuus
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Depth of focus through different intraocular lenses in patients with different corneal profiles using adaptive optics visual simulation

2011

PURPOSE: To evaluate the depth of focus with monofocal intraocular lenses (IOLs) in patients with different corneal profiles using adaptive optics (AO) visual simulation. METHODS: An AO visual simulator (crx1, Imagine Eyes) was used to simulate the aberration pattern of three monofocal IOLs (Acrysof IQ SN60WF [Alcon Laboratories Inc]; Akreos Adapt AO [Bausch & Lomb]; and Triplato [AJL Ophthalmic]) of different optic designs. Five groups were considered: patients without any corneal refractive surgery (normal cornea group) and with prior low and high myopic and hyperopic ablations (low myopic ablation, high myopic ablation, low hyperopic ablation, and high hyperopic ablation groups). De…

AdultDepth of focusVisual acuityCorneal Wavefront AberrationPseudophakiagenetic structuresmedicine.medical_treatmentVisual AcuityCorneaYoung AdultLens Implantation IntraocularCorneaRefractive surgerymedicineHumansDioptreLenses IntraocularDepth Perceptionbusiness.industryAblationRefractive Errorseye diseasesOphthalmologySpherical aberrationmedicine.anatomical_structureOptometryOftalmologíaSurgerysense organsmedicine.symptomDepth perceptionbusiness
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Jealousy at work: The role of rivals’ characteristics

2018

The present study examined rival characteristics that may evoke jealousy in the workplace, differences between men and women in this regard, and the relationship between jealousy responses and intrasexual competitiveness and social comparison orientation. Participants were 426 male and female employees. By means of a questionnaire, participants were presented with a jealousy-evoking scenario after which jealousy responses to 24 rival characteristics were assessed. Findings showed that a rival's social communal attributes evoked highest levels of jealousy, and that, compared to men, women reported more jealousy in response to a rival's physical attractiveness. Overall, as individuals had hig…

AdultEmploymentMalesex differencesCompetitive BehaviorSEX-DIFFERENCESSocial comparison orientationmedia_common.quotation_subjectJealousy050109 social psychologyINDIVIDUAL-DIFFERENCES050105 experimental psychologyJealousyworkArts and Humanities (miscellaneous)social comparisonINTRASEXUAL COMPETITIONTESTOSTERONEDevelopmental and Educational PsychologymedicineHumansInterpersonal Relations0501 psychology and cognitive sciencesNEGATIVE EMOTIONSreproductive and urinary physiologyGeneral PsychologyCONFLICTmedia_commonSocial comparison theoryurogenital systemAggression05 social sciencesPhysical attractivenessGeneral MedicineMiddle AgedhumanitiesDominance (ethology)Social PerceptionDOMINANCESexual selectionFEMALE COMPETITIONAGGRESSIONFemaleWORKPLACEmedicine.symptomPsychologySocial psychologyScandinavian Journal of Psychology
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Haemorheological parameters in young patients with acute myocardial infarction

2008

The role played by hemorheological alterations on acute myocardial infarction (AMI) in young patients remains a question of debate. We have carried out a case-control study of 84 AMI patients aged45 years and 135 sex and age matched controls, in which blood viscosity (BV), plasma viscosity (PV), erythrocyte aggregation (EA) performed with the Myrenne (EA0, EA1) and the Sefam aggregometer (Ta, AI10, gammaD), erythrocyte deformability (ED) along with fibrinogen (Fbg), C-reactive protein (CRP) and plasmatic lipids i.e. total cholesterol (T-Chol) and triglycerides (TG) were determined. AMI patients showed higher, Fbg, TG, EA0, EA1, IA10, gammaD and lower Ta than controls (p=0.029, p0.001, p=0.0…

AdultErythrocyte AggregationMaleRiskmedicine.medical_specialtyErythrocytesPhysiologyBlood viscosityMyocardial InfarctionErythrocyte aggregationErythrocyte DeformabilityPhysiology (medical)Internal medicineHumansMedicineErythrocyte deformabilityMyocardial infarctionbusiness.industryCase-control studyFibrinogenHematologyMiddle AgedBlood Viscositymedicine.diseaseC-Reactive ProteinCase-Control StudiesHemorheologyCardiologyPhysical therapyFemaleCardiology and Cardiovascular MedicinebusinessClinical Hemorheology and Microcirculation
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Potential effects of age-associated oxidative stress on mammalian oocytes/embryos

1996

This bioessay aims to explain the different effects of maternal ageing and postovulatory oocyte ageing on mammalian oocytes/embryos under the scope of 'the oxygen radical-mitochondrial injury hypothesis of ageing'. This hypothesis assumes a key role in the senescent process of oxygen radical damage to mitochondrial DNA, proteins and lipids. It is proposed that a decrease in intracellular ATP concentrations and glutathione (GSH)/glutathione disulphide (GSSG) ratio together with a concomitant increase in cytosolic Ca2+ are major factors causing the observed detrimental effects of ageing on cytoskeletal fibres, fertilization and embryo development.

AdultFetal ProteinsEmbryologyBiologymedicine.disease_causeDNA MitochondrialCongenital AbnormalitiesMicechemistry.chemical_compoundAdenosine TriphosphateNeoplasmsGeneticsmedicineAnimalsHumansMolecular BiologyCellular SenescenceCytoskeletonMammalsEgg ProteinsEmbryogenesisObstetrics and GynecologyEmbryoCell BiologyGlutathioneEmbryo MammalianOocyteGlutathioneCell biologyOxidative StressCytosolFertilitymedicine.anatomical_structureReproductive MedicineBiochemistrychemistryAgeingFertilizationOocytesReactive Oxygen SpeciesOxidation-ReductionIntracellularOxidative stressMaternal AgeDevelopmental BiologyMolecular Human Reproduction
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Awareness of HPV infection and attitudes toward HPV vaccination among Latvian adolescents

2016

Objective\ud To evaluate awareness of HPV and its vaccine among Latvian adolescents.\ud \ud Methods\ud A cross‐sectional survey was conducted in a 2‐week period in September 2015 among 270 adolescents attending a secondary school in Riga, Latvia. All students present during sexual‐health classes (grades 10–12 [aged 16–21 years]) were included. A self‐administered paper‐based survey assessed sociodemographic factors, sexual behaviours, smear history and knowledge of sexually transmitted infections, HPV and HPV vaccine knowledge, and sources of information.\ud \ud Results\ud Overall, 121 surveys were completed (62 by male students and 59 by female students). Latvian adolescents lacked awarene…

AdultHealth Knowledge Attitudes PracticeAdolescentPopulationUterine Cervical Neoplasms03 medical and health sciencesSexually active0302 clinical medicineRA0421Surveys and QuestionnairesPrevalenceHumansMedicinePapillomavirus Vaccines030212 general & internal medicineeducationFemale studentseducation.field_of_studyHigh prevalencebusiness.industryPapillomavirus InfectionsHPV infectionObstetrics and GynecologyLatvianHpv vaccinationGeneral MedicinePatient Acceptance of Health Caremedicine.diseaseLatviaR1female genital diseases and pregnancy complicationslanguage.human_languageVaccinationAdolescent Behavior030220 oncology & carcinogenesisImmunologylanguageWomen's HealthFemalebusinessDemographyInternational Journal of Gynecology & Obstetrics
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Changes in Tear Protein Pattern after Photorefractive Keratectomy

2003

PURPOSE. Changes in tear protein composition of patients who underwent photorefractive keratectomy (PRK) were analyzed. METHODS. Tear samples were obtained from 23 eyes of 23 patients immediately before PRK and on the fourth postoperative day with glass capillaries. Tear proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Digital image analysis and evaluation of the densitometric data of the electrophoretic separations were done with BioDoc-Analyze. RESULTS. Analysis of discriminance found a significant difference in the protein patterns (p<0.001). This type of analysis of the electrophoretic densitographs uses all peak information simultaneously. A signifi…

AdultImmunoglobulin APathologymedicine.medical_specialtymedicine.medical_treatmentEye diseaseLacrimal glandPhotorefractive KeratectomyCornea03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCorneaOphthalmologyHumansMedicinePostoperative PeriodEye ProteinsGel electrophoresisbiologybusiness.industryLactoferrinLacrimal ApparatusGeneral MedicineMiddle Agedmedicine.diseaseeye diseasesPhotorefractive keratectomyOphthalmologymedicine.anatomical_structurechemistryTears030221 ophthalmology & optometrybiology.proteinElectrophoresis Polyacrylamide GelLasers Excimersense organsLysozymebusiness030217 neurology & neurosurgeryEuropean Journal of Ophthalmology
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