Search results for "actors"

showing 10 items of 11323 documents

Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population: a nationwide observation…

2022

AbstractThe detection of antinuclear autoantibody (ANA) is dependent on many factors and varies between the populations. The aim of the study was first to assess the prevalence of ANA in the Polish adult population depending on age, sex and the cutoff threshold used for the results obtained. Second, we estimated the occurrence of individual types of ANA-staining patterns. We tested 1731 patient samples using commercially available IIFA using two cutoff thresholds of 1:100 and 1:160. We found ANA in 260 participants (15.0%), but the percentage of positive results strongly depended on the cutoff level. For a cutoff threshold 1:100, the positive population was 19.5% and for the 1:160 cutoff th…

musculoskeletal diseasesAdultMaleRMAnti-nuclear antibodyCross-sectional studyIndirect immunofluorescence assayImmunologyPopulationAdult populationPolish populationObservational ResearchAutoimmune DiseasesAgeSex FactorsRheumatologyCutof thresholdPrevalenceImmunology and AllergyCutoffMedicineHumanseducationskin and connective tissue diseasesQH426education.field_of_studybusiness.industryAutoantibodyAge FactorsMiddle AgedQRCutoff thresholdstomatognathic diseasesAntinuclear antibodiesCross-Sectional StudiesIndirect immunofuorescence assayAntibodies AntinuclearQR180Observational studySexFemalePolandbusinessDemographyRheumatology International
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Plantar pressure distribution analysis in normal weight young women and men with normal and claw feet: a cross-sectional study

2005

We analyzed the plantar support in 72 normal-weight young voluntaries (46 women, 26 men), by a baropodometric platform. We considered subjects with claw foot (CFS) and subjects with normal foot (NFS). We found a significant reduction of total plantar support surface in the CFS (P < 0.0001 for women, P < 0.001 for men), due to the reduction of the forefoot and rear foot areas of both plantar imprints. Indeed, CFS of both sexes exhibited higher values of both plantar pressure and peak pressure, compared to the NFS. Moreover, the load per units of plantar surface increased in CFS compared to the NFS. In conclusion, the reduction of plantar support surfaces in CFS of both sexes was associated t…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyClawHistologyAdolescentCross-sectional studyCumulative Trauma Disordersmedicine.disease_causebaropodometer;claw foot;plantar pressure distributionWeight-bearingclaw footWeight-BearingSex FactorsRisk FactorsmedicinePressureHumansbaropodometerRisk factorFoot InjuriesOrthodonticsbusiness.industryPlantar pressureForefootHammer Toe SyndromeGeneral Medicineplantar pressure distributionSurgeryBiomechanical Phenomenabody regionsCross-Sectional StudiesNormal weightFemaleAnatomybusinesshuman activitiesFoot (unit)
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Dairy calcium intake and lifestyle risk factors for bone loss in hiv-infected and uninfected mediterranean subjects

2012

Abstract Background Despite the reported high prevalence of osteoporosis in the human immunodeficiency virus (HIV)-population, there have been no previous studies examining dairy calcium intake and bone mineral density (BMD) in HIV-subjects. We assessed the prevalence of low BMD in HIV-infected and uninfected subjects and analyzed the effects of calcium intake, lifestyle and HIV-related risk factors on BMD. Methods One hundred and twelve HIV-infected subjects were consecutively enrolled. Seventy- six HIV-uninfected subjects matched for age and sex were enrolled as the control group. The HIV-subjects were interviewed about lifestyle habits and completed a weekly food-frequency questionnaire …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyFRAXSettore MED/09 - Medicina InternaBone densitySettore MED/17 - Malattie InfettiveOsteoporosisHIV Infectionslcsh:Infectious and parasitic diseasesBone remodelingAbsorptiometry PhotonBone DensityRisk FactorsSurveys and QuestionnairesInternal medicineVitamin D and neurologyBone mineral densityHumansMedicinelcsh:RC109-216Life StyleBone mineralMediterranean Regionbusiness.industryOsteopeniaCase-control studyOsteoporosiHIVMiddle AgedDairy intakemedicine.diseaseDietOsteopeniaInfectious DiseasesEndocrinologyCase-Control StudiesOsteoporosisCalciumFemalebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaResearch Article
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Rates of Upper Facet Joint Violation in Minimally Invasive Percutaneous and Open Instrumentation: A Comparative Cohort Study of Different Insertion T…

2017

Background Minimally invasive pedicle screw placement may have a higher incidence of violation of the superior cephalad unfused facet joint. Study Aims We investigated the incidence and risk factors of upper facet joint violation in percutaneous robot-assisted instrumentation versus percutaneous fluoroscopy-guided and open transpedicular instrumentation. Methods A retrospective study including all consecutive patients who underwent lumbar instrumentation, fusion, and decompression for spondylolisthetic stenosis and degenerative disk disease was conducted between January 2012 and January 2016. All operations were performed by the same surgeon; the patients were divided into three groups acc…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyPercutaneousDecompressionIntervertebral Disc DegenerationSurgical planningNeurosurgical ProceduresZygapophyseal JointFacet joint03 medical and health sciences0302 clinical medicineLumbarSpinal StenosisPedicle ScrewsRisk FactorsmedicineHumansInstrumentation (computer programming)AgedRetrospective Studies030222 orthopedicsLumbar Vertebraebusiness.industryRetrospective cohort studyMiddle Agedmusculoskeletal systemmedicine.diseaseSurgeryStenosismedicine.anatomical_structureSpinal FusionTreatment OutcomeSurgeryFemaleNeurology (clinical)business030217 neurology & neurosurgeryJournal of neurological surgery. Part A, Central European neurosurgery
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Manometric assessment of oesophageal involvement in progressive systemic sclerosis, morphoea and Raynaud's disease.

1982

SUMMARY Oesophageal function was studied by radiography and manometry in fifty-one patients with progressive systemic sclerosis (PSS), fourteen patients with morphoea, twelve patients with Raynaud's disease and twenty-one normal subjects. Upper oesophageal sphincter pressure was not affected. Peristaltic contractions of the upper third of the oesophagus were significantly decreased in PSS and morphoea, but the lower two-thirds were affected only in PSS. Lower oesophageal sphincter pressure was significantly decreased in PSS but was normal in morphoea and Raynaud's disease. There was a significant correlation between oesophageal dysfunction and the duration of PSS. Manometry was better than …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyTime FactorsOesophageal manometryAdolescentManometryRadiographyDermatologySkin DiseasesScleroderma LocalizedEsophagusstomatognathic systemLower oesophageal sphincter pressurePressureMedicineUpper oesophageal sphincter pressureHumansAgedScleroderma Systemicbusiness.industryProgressive systemic sclerosisRaynaud DiseaseMiddle Agedmedicine.diseaseeye diseasesRadiographystomatognathic diseasesRaynaud's diseaseFemaleUpper thirdRadiologyOesophageal functionbusinessThe British journal of dermatology
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A ten-year follow-up of the Reflection cementless acetabular component.

2008

We reviewed the long-term results at ten to 12 years of 118 total hip replacements in 109 patients using a second-generation hemispherical cementless acetabular component (Reflection) designed to address the problem of backside wear. Five patients (five hips) died and six patients (seven hips) were lost to follow-up. The remaining 98 patients (106 hips) had a mean age of 62.9 years (34.0 to 86.2) A rate of revision for aseptic loosening of 0.9%, and predictable results were found with respect to radiological evidence of fixation, lack of pain, walking ability, range of movement and function. One component was revised for aseptic loosening, and of the 101 hips (95.2%) that did not have a rev…

musculoskeletal diseasesAdultmedicine.medical_specialtyAcetabulum; Adult; Aged; Aged 80 and over; Arthroplasty Replacement Hip; Bone Cements; Equipment Failure Analysis; Follow-Up Studies; Hip Joint; Humans; Middle Aged; Osteoarthritis Hip; Prosthesis Design; Prosthesis Failure; Statistics as Topic; Time Factors; Hip ProsthesisTime FactorsArthroplasty Replacement HipStatistics as TopicProsthesis DesignOsteoarthritis HipmedicineHumansOrthopedics and Sports MedicineSurvival analysisPelvisFixation (histology)AgedAged 80 and overbusiness.industryBone CementsAcetabulumMiddle AgedConfidence intervalSurgeryProsthesis FailureEquipment Failure AnalysisReflection acetabular component hipmedicine.anatomical_structureAcetabular componentRadiological weaponCohortOrthopedic surgerySurgeryHip JointHip ProsthesisbusinessFollow-Up StudiesThe Journal of bone and joint surgery. British volume
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Phenotypic spectrum and genomics of undiagnosed arthrogryposis multiplex congenital

2022

BackgroundArthrogryposis multiplex congenita (AMC) is characterised by congenital joint contractures in two or more body areas. AMC exhibits wide phenotypic and genetic heterogeneity. Our goals were to improve the genetic diagnosis rates of AMC, to evaluate the added value of whole exome sequencing (WES) compared with targeted exome sequencing (TES) and to identify new genes in 315 unrelated undiagnosed AMC families.MethodsSeveral genomic approaches were used including genetic mapping of disease loci in multiplex or consanguineous families, TES then WES. Sanger sequencing was performed to identify or validate variants.ResultsWe achieved disease gene identification in 52.7% of AMC index pati…

musculoskeletal diseasesArtrogriposi múltiple congènitaSettore BIO/18 - GENETICAhuman geneticsneuromuscular diseasesGenomicsBiologyCONTRACTURESCLASSIFICATIONdiseasessymbols.namesakeDiagnòsticGene mappingarthrogryposis multiplex congenitaExome SequencingOF-FUNCTION MUTATIONSGeneticsMedicine and Health SciencesgenomicsHumansGenetics (clinical)Exome sequencingArthrogryposisSanger sequencingGeneticsArthrogryposis multiplex congenitaGenetic heterogeneitySPINAL MUSCULAR-ATROPHYProteinsnervous system malformationsDYSTROPHYDisease gene identificationGENEHuman geneticsPedigreeETIOLOGYPhenotypesymbolsneuromuscularGenèticaTranscription Factors
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Estimation of structural and geometrical properties of cortical bone by computerized tomography in 78-year-old women

2009

The structural and geometrical properties of the tibia shaft were investigated at two sections by means of computerized tomography (CT) in 78-year-old women with high (n = 19) and low (n = 17) calcaneal bone mineral density (BMD, g/cm3) previously measured by 125I-photon absorption. The high BMD group had a 20-21% higher tibial BMD and 9-12% higher bone cross-sectional area than was observed in the low BMD group. The distribution of bone mass indicated that the low BMD group had lost bone mainly from the endosteal surface, especially in the anterior part of the tibia. However, both groups had a similar basic pattern of mass distribution at the measured sections. The high BMD group had highe…

musculoskeletal diseasesBone densityEndocrinology Diabetes and MetabolismBody Mass IndexFractures BoneAbsorptiometry PhotonBone DensityRisk FactorsmedicineAnimalsHumansOrthopedics and Sports MedicineTibiaAgedBone mineralOrthodonticsTibiaBody WeightBiomechanicsAnatomymusculoskeletal systemBiomechanical PhenomenaCalcaneusmedicine.anatomical_structureCattleFemaleCortical boneTomographyCalcaneusBody mass indexMathematicsTomography Emission-ComputedJournal of Bone and Mineral Research
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Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint disease

2011

14 páginas, 8 figuras, 1 tabla.-- et al.

musculoskeletal diseasesGenetically modified mouseMedicinaNF-E2-Related Factor 2PhysiologyChemokine CXCL1Clinical BiochemistryNitric Oxide Synthase Type IIArthritisMice Transgenicmedicine.disease_causeenvironment and public healthBiochemistryNrf2MicemedicineAnimalsMolecular BiologyGeneral Environmental SciencebiologyInterleukin-6Effectorbusiness.industryArthritisInflammation and degenerationCell Biologyrespiratory systemmedicine.diseaseArthritis ExperimentalInfection and autoimmunity Auto-immunity transplantation and immunotherapy [NCMLS 1]Disease Models AnimalOxidative StressEicosanoidCyclooxygenase 2Rheumatoid arthritisTumor Necrosis FactorsImmunologyOsteocalcinbiology.proteinGeneral Earth and Planetary SciencesJointsTumor necrosis factor alphaImmune Regulation Auto-immunity transplantation and immunotherapy [NCMLS 2]businessOxidation-ReductionHeme Oxygenase-1Oxidative stress
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Nonadherence in outpatient thrombosis prophylaxis with low molecular weight heparins after major orthopaedic surgery

2010

Background: According to some current guidelines, extended thromboprophylaxis after hip and knee arthroplasties is recommended. Outpatient prophylaxis with low molecular weight heparins (LMWH) is an important part of this prophylaxis, although the rates of adherence to these regimens is not known. Questions/purposes: We determined (1) the degree of nonadherence (NA) of patients with LMWH outpatient prophylaxis, and (2) whether specific independent factors explain NA. Methods: NA was determined by syringe count and by indirect and direct questions to patients. We defined six different NA indicators. To identify factors explaining LMWH NA, we used three different logistic regression models. R…

musculoskeletal diseasesMaleQuestionnairesmedicine.medical_specialtyHealth Knowledge Attitudes PracticeTime Factorsmedicine.drug_classmedicine.medical_treatmentArthroplasty Replacement HipLow molecular weight heparinRisk AssessmentInjectionsMedication AdherenceAmbulatory careFibrinolytic AgentsClinical ResearchRisk FactorsInternal medicineSurveys and QuestionnairesGermanyAmbulatory CareMedicineHumansOrthopedics and Sports Medicine/dk/atira/pure/core/keywords/559092180Arthroplasty Replacement KneeAgedbusiness.industryAnticoagulantHealth sciencesThrombosisGeneral MedicineHeparinHeparin Low-Molecular-Weightmedicine.diseaseThrombosisArthroplastySurgeryTelephoneLogistic ModelsTreatment OutcomeOrthopedic surgerySurgeryFemalebusinessFibrinolytic agentmedicine.drug
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