Search results for "aggregates"

STUDIES ON ALKALY METAL HALIDES AGGREGATES IN GAS PHASE

2012

A Par j1/Par J2-polymeric nanoaggragates as a new tool for allergy vaccination

2013

Molecular dynamics of electrosprayed water nanodroplets containing sodium bis(2-ethylhexyl)sulfosuccinate

2013

The behavior of aqueous solutions of sodium bis(2-ethylhexyl)sulfosuccinate (AOTNa) subject to electrospray ionization (ESI) has been investigated by molecular dynamics (MD) simulations at three temperatures (350, 500 and 800 K). We consider several types of water nanodroplets containing AOTNa molecules and composed of a fixed number of water molecules (1000), N(AOT)(0) AOT(-) anions (N(AOT)(0) =  0, 5, 10) and N(Na)(0) sodium ions (N(Na)(0) =  0, 5, 10, 15, 20): in a short time scale (less than 1 ns), the AOTNa molecules, initially forming direct micelles in the interior of the water nanodroplets, are observed in all cases to diffuse nearby the nanodroplet surface, so that the hydrophilic …

Sigma-1 Receptor Activation Induces Autophagy and Increases Proteostasis Capacity In Vitro and In Vivo

2019

Dysfunction of autophagy and disturbed protein homeostasis are linked to the pathogenesis of human neurodegenerative diseases and the modulation of autophagy as the protein clearance process has become one key pharmacological target. Due to the role of sigma-1 receptors (Sig-1R) in learning and memory, and the described pleiotropic neuroprotective effects in various experimental paradigms, Sig-1R activation is recognized as one potential approach for prevention and therapy of neurodegeneration and, interestingly, in amyotrophic lateral sclerosis associated with mutated Sig-1R, autophagy is disturbed. Here we analyzed the effects of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hyd…

Surfactant Self-Assembling in the Gas Phase:bis(2-ethylhexyl)sulfosuccinate-Metal Ion Aggregates

2009

Non-Centrosymmetric Homochiral Supramolecular Polymers of Tetrahedral Subphthalocyanine Molecules

2015

This is the peer reviewed version of the following article: Angewandte Chemie - International Edition 54.8 (2015): 2543-2547, which has been published in final form at http://dx.doi.org/10.1002/anie.201411272. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving

Long-term cropping systems and tillage management effects on soil organic carbon stocks and steady state level of C sequestration rates in a semiarid…

2010

A calcareous and clayey xeric Chromic Haploxerept of a long-term experimental site in Sicily (Italy) was sampled (0–15 cm depth) under different land use management and cropping systems (CSs) to study their effect on soil aggregate stability and organic carbon (SOC). The experimental site had three tillage managements (no till [NT], dual-layer [DL] and conventional tillage [CT]) and two CSs (durum wheat monocropping [W] and durum wheat/faba bean rotation [WB]). The annually sequestered SOC with W was 2·75-times higher than with WB. SOC concentrations were also higher. Both NT and CT management systems were the most effective in SOC sequestration whereas with DL system no C was sequestered. …

Self-assembly of fluorescent diimidazolium salts: tailor properties of the aggregates changing alkyl chain features

2016

Searching for new fluorescent organic salts to be used in biomedical and electrochemical field, we conjugated properties of imidazolium salts with the ones of naphthalene diimide core and we obtained some N,N′-bis-(1-alkyl-3-propylimidazolium)naphthalene diimide diiodides. We took into account alkyl chains going from hexyl to dodecyl, as well as hydrogenated and fluorinated alkyl tails. After determination of their thermal behaviour by differential scanning calorimetry, concentration-, and temperature-dependent spectroscopic studies (UV-vis and fluorescence) were performed evidencing the occurrence of isodesmic and enthalpy-driven self-assembly processes. Properties of aggregates were also …

Aggregation in aqueous media of tri-block copolymers tuned by the molecular selectivity of cyclodextrins

2009

The water + cyclodextrin + poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) mixtures have been investigated to explore the temperature effect on the aggregation of the copolymer in the presence of cyclodextrins (CDs). The CDs with different cavity sizes were chosen because they may include either the hydrophilic poly(ethylene oxides) block or both kinds of blocks. The differential scanning calorimetry and viscosity experiments straightforwardly evidenced that the critical micellar temperature is shifted to larger values by adding a CD which is able to include the middle poly(propylene oxide) block while it is not influenced by the presence of CD which is selective to the poly…

Electrospray ion mobility mass spectrometry of positively charged sodium bis[2-ethythexyl)sulfosuccinate aggregates.

2014

Collision cross-sections (CCS) of positively singly and multiply charged aggregates of the surfactant sodium bis(2-ethylhexyl)sulfosuccinate (AOTNa) in the gas phase have been measured by quadrupole ion mobility time-of-flight mass spectrometry. Calibration of the observed drift times to the CCS of the AOTNa non-covalent aggregates was achieved by collecting, under the same experimental conditions, the drift times of a range of singly and multiply charged polyalanine peptides whose CCS had been obtained by conventional ion mobility spectrometry. Together with an obvious increase of the aggregate cross-section with the aggregation number, it was found that the aggregate cross-section increa…