Search results for "aging"

Decagram-Scale Synthesis of Multicolor Carbon Nanodots: Self-Tracking Nanoheaters with Inherent and Selective Anticancer Properties

2022

Carbon nanodots (CDs) are a new class of carbon-based nanoparticles endowed with photoluminescence, high specific surface area, and good photothermal conversion, which have spearheaded many breakthroughs in medicine, especially in drug delivery and cancer theranostics. However, the tight control of their structural, optical, and biological properties and the synthesis scale-up have been very difficult so far. Here, we report for the first time an efficient protocol for the one-step synthesis of decagram-scale quantities of N,S-doped CDs with a narrow size distribution, along with a single nanostructure multicolor emission, high near-infrared (NIR) photothermal conversion efficiency, and sel…

Synthetic and natural polymer nanoparticles as bio-imaging and therapeutic agent vectors

2014

Thrombolysis Followed by Apixaban for Massive Pulmonary Embolism and Free-floating Thrombus in Right Ventricle in a Patient with Breast Cancer

2018

Free-floating thrombus in the right ventricle, associated with a massive acute pulmonary embolism (PE), is a rare phenomenon. PE is an important clinical entity with considerable mortality despite advances in diagnosis and treatment. The prognosis of PE depends on right ventricular dysfunction, myocardial injury markers, and early treatment. In this report, we present the case of a 71-year-old woman with a history of breast cancer admitted to intensive care unit for PE complicated by syncope. Although our case may seem complex because it is not represented in the guidelines, the result was satisfactory and showed how treatment with new anticoagulants (in this case apixaban) after massive th…

THYROID DISORDERS

2012

Kinematic analysis of motor strategies in frail aged adults during the Timed Up and Go: how to spot the motor frailty?

2015

Asma Hassani,1 Alexandre Kubicki,2,3 Vincent Brost,1 France Mourey,2,4 Fan Yang1 1Laboratoire LE2I CNRS 6306, Université de Bourgogne, Dijon, France; 2Institut National de la Santé et de la Recherche Médicale (INSERM), Cognition Action et Plasticité Sensori-Motrice, Campus Universitaire, Université de Bourgogne, Dijon, France; 3Centre Hospitalier Universitaire de Dijon, Hôpital de Champmaillot, Dijon, France; 4Faculté de Médecine, Université de Bourgogne, Dijon, France Objective: The purpose of this work was to analyze and compare the movement kinematics of sit-to-stand (STS) and back-to-sit (BTS) transfers between frail aged adu…

The role of motor system in action-related language comprehension in L1 and L2: An fMRI study

2018

The framework of embodied cognition has challenged the modular view of a language-cognition divide by suggesting that meaning-retrieval critically involves the sensory-motor system. Despite extensive research into the neural mechanisms underlying language-motor coupling, it remains unclear how the motor system might be differentially engaged by different levels of linguistic abstraction and language proficiency. To address this issue, we used fMRI to quantify neural activations in brain regions underlying motor and language processing in Chinese-English speakers’ processing of literal, metaphorical, and abstract language in their L1 and L2. Results overall revealed a response in motor ROIs …

Confocal laser scanning microscopy for the study of the morphological changes of the postextraction sites

2012

A better understanding of the remodeling process of postextraction sockets is essential in dental treatment planning. The aim of this study was to evaluate whether confocal laser scanning microscopy (CLSM) can be applied to imaging contour changes of postextraction sites, as well as to its quantification with image analysis of obtained three-dimensional images. This work describes a new application of the CLSM technique. The system used was the OLS3100-USS, LEXT model (Olympus((R))). CLSM was used for the surface analysis of the extraction site. The measurements taken with CLSM were: (1) mesio-distal distance, (2) alveolar ridge thickness, and (3) vestibular and lingual alveolar ridge heigh…

Evaluation of Surgical Outcomes of Abdominal Radical Hysterectomy and Total Laparoscopic Radical Hysterectomy for Cervical Cancer: A Retrospective An…

2022

Although a surgical approach is one of the key treatments for stages IA1-IIA2, results of the Laparoscopic Approach to Cervical Cancer (LACC) published in 2018 radically changed the field, since minimally invasive surgery was associated with a four-fold higher rate of recurrence and a six-fold higher rate of all-cause death compared to an open approach. We aimed to evaluate surgical outcomes of abdominal radical hysterectomy (ARH) and total laparoscopic radical hysterectomy (TLRH) for cervical cancer, including data collected before the LACC trial. In our retrospective analysis, operative time was significantly longer in TLRH compared to ARH (p < 0.0001), although this disadvantage could…

Il packaging come icona culturale? Processi di significazione e meccanismi intertestuali

2020

Questo contributo si interroga sul modo in cui alcune confezioni dei prodotti possano assurgere a icone culturali in grado di condensare, e al tempo stesso trascendere e rilanciare, ampi significati di tipo socioculturale. I packaging di alcuni brand mondiali, gia da tempo, sono diventati non solo segno inconfondibile del brand di appartenenza (si pensi alla contour di Coca-Cola o al barattolo di Nutella), ma anche oggetti in grado di comunicare molto altro, che finiscono per sganciarsi dal marchio e contribuiscono a far circolare valori di consumo, abitudini di un’epoca, usi collettivi di una certa cultura. Attraverso l’analisi di alcuni casi studio, indagheremo proprio quali sono i proces…

Saako monikielisessä koulussa puhua ruotsia? : Får man prata finska i den flerspråkiga skolan?

2018

Suomen ja ruotsin sekoittumisen välttämiseksi on nähty vaivaa suomalaisessa koulujärjestelmässä. Nyt monikielisyys myllertää koulujen kielikäytänteet uudenlaisiksi. Artikkelissa kysytään, purkaako koulun monikielistyminen raja- aidan myös kahden virallisen kielen väliltä. Toinen vaihtoehto on ajautua kaksinaisjärjestelmään, jossa viralliset enemmistökielet suomi ja ruotsi pidetään erillään toisistaan, samalla kun uudet vähemmistökielet asettuvat koulun käytänteisiin limittäin kulloisenkin opetuskielen kanssa. nonPeerReviewed