Search results for "amine"
showing 10 items of 7299 documents
ChemInform Abstract: Reaction of 2,2′-Bis(N-methylindolyl) with Dimethyl Acetylenedicarboxylate and Thermally and Photochemically Induced Cyclization…
2010
2,2′-Bis(N-methylindolyl) 1 reacts with dimethyl acetylenedicarboxylate to furnish the 3-dimethyl maleoyl-substituted 2,2′-bisindolyl 2. Compound 2 cyclizes under aluminum trichloride catalysis according to a polar process to give a cyclopenta[2,1-b:3,4-b′]diindole derivative 4. Reaction of compound 4 with benzyl-amine yields the spiro derivative 5. Photochemically-induced 1,6-electrocyclization of compound 2 gives rise to the indolo[2,3-a]carbazole 6 directly, which is readily transformed to the pyrrolo-annelated carbazole 7 by treatment with benzylamine.
Reaction of 2,2′-bis(N-methylindolyl) with dimethyl acetylenedicarboxylate and thermally- and photochemically-induced cyclizations of the product
1995
2,2′-Bis(N-methylindolyl) 1 reacts with dimethyl acetylenedicarboxylate to furnish the 3-dimethyl maleoyl-substituted 2,2′-bisindolyl 2. Compound 2 cyclizes under aluminum trichloride catalysis according to a polar process to give a cyclopenta[2,1-b:3,4-b′]diindole derivative 4. Reaction of compound 4 with benzyl-amine yields the spiro derivative 5. Photochemically-induced 1,6-electrocyclization of compound 2 gives rise to the indolo[2,3-a]carbazole 6 directly, which is readily transformed to the pyrrolo-annelated carbazole 7 by treatment with benzylamine.
ansa-[(tert-Butylamino)(isodicyclopentadienyl)dimethylsilane]Zr(NMe2)2prepared by an amine-elimination reaction
2003
An amine-elimination reaction was used to obtain the title compound, i.e. (N-tert-butyl-N-[[(1,2,3,3a,7a-eta)-4,5,6,7-tetrahydro-4,7-methano-1H-inden-2-yl]dimethylsilyl]amido-kappaN)bis(N-methylmethanaminato-kappaN)zirconium(IV) or [isodiCpSiMe(2)N-tert-butyl]Zr(NMe(2))(2) (Cp is cyclopentadienyl), [Zr(C(16)H(25)NSi)(C(2)H(6)N)(2)], in very good yield. Treatment of isodiCpHSiMe(2)NH-tert-butyl with Zr(NMe(2))(4) leads to the formation of a yellow solid that can be purified by sublimation. The single-crystal structure of the product shows the exo complexation of the isodicyclopentadienyl ligand to the Zr atom. The Cp portion of this ligand is bonded to the Zr atom in a eta(5) manner, with a …
Spectrophotometric and voltammetric determination of 2,5-dimethylaniline as potential product of enzymatic splitting of XY-2,5-dimethylanilide type s…
1999
A method for determination of 2,5-dimethylaniline is proposed. The procedure enables both spectrophotometrical and voltammetric measurements. The spectrophotometrical determination at λmax = 385.8 nm is possible for concentrations up to 1.25 × 10-6 mol l-1. The voltammetric method takes more time, however, due to the adsorptive enrichment of the substrate it is possible to determine concentrations in the range of 10-7 mol l-1). In the paper the optimal conditions and parameters for the determination are suggested.
Hybrid Engagement: Discourses and Scenarios of Entrepreneurial Journalism
2018
Although the challenge posed by social media and the participatory turn concerns culture and values at the very heart of journalism, journalists have been reluctant to adopt participatory values and practices. To encourage audience participation and to offer journalism that is both trustworthy and engaging, journalists of the future may embrace a hybrid practice of journalistic objectivity and audience-centred dialogue. As innovative and experimental actors, entrepreneurial journalism outlets can perform as forerunners of such a culture. By analysing discourses in the “About Us” pages of 41 entrepreneurial journalism outlets, the article examines the emerging journalistic ethos of entrepren…
Auttamisen diskursiivinen rakentuminen Facebookissa Refugees Welcome Keski-Suomi -sivulla
2016
Maisterintutkielmassani tarkastelen, miten turvapaikanhakijoiden auttaminen rakentuu diskursiivisesti Facebookissa Refugees Welcome Keski-Suomi -sivulla. Euroopan pakolaiskriisin myötä Suomeen saapui viime vuonna yli 30 000 turvapaikanhakijaa, mikä synnytti kansalaisten keskuudessa auttamishalun, jollaista ei ole aikaisemmin Suomen mittakaavassa nähty. Tarkastelemani Facebook -sivu perustettiin turvapaikanhakijoiden auttamisen koordinoimiseksi. Vastaavanlaista sivustoa ei ole aikaisemmin perustettu, joten kyseessä on varsin uusi sosiaalisen median ilmiö. Päätutkimuskysymykseni on: Miten auttaminen rakentuu diskursiivisesti Facebookissa Refugees Welcome Keski-Suomi -sivulla? Tämä kysymys jak…
Oxidation of dobutamine and dopamine by horseradish peroxidase
2022
Dobutamine and dopamine have been previously shown to interfere with enzymatic diagnostic tests and different mechanisms responsible for this effect have been postulated. We have studied the oxidation by horseradish peroxidase (HRP) of dopamine, dobutamine, and its analog with the phenol group blocked by methylation. Oxidation of dobutamine was much faster than dopamine, as reported before, whereas the methylated analog of dobutamine was oxidized at intermediate rate. This demonstrates that the phenol group in dobutamine is oxidized preferentially by HRP and acts as an electron-transfer mediator in oxidation of the catechol group. Different oxidation rates of catechol groups in dopamine and…
Biogenic amine levels, reproduction and social dominance in the queenless ant Streblognathus peetersi
2006
Social harmony often relies on ritualized dominance interactions between society members, particularly in queenless ant societies, where colony members do not have developmentally predetermined castes but have to fight for their status in the reproductive and work hierarchy. In this behavioural plasticity, their social organisation resembles more that of vertebrates than that of the "classic" social insects. The present study investigates the neurochemistry of the queenless ant species, Streblognathus peetersi, to better understand the neural basis of the high behavioural plasticity observed in queenless ants. We report measurements of brain biogenic amines [octopamine, dopamine, serotonin]…
Effects of acute social stress on the conditioned place preference induced by MDMA in adolescent and adult mice
2014
Exposure to social defeat stress increases the rewarding effects of psychostimulants in animal models, but its effect on 3,4-methylenedioxymethylamphetamine (MDMA) reward has received little attention. In the present study, we evaluated the influence of social defeat on the rewarding effects of MDMA in adolescent [postnatal day (PND) 29-40] and adult (PND 50-61) male mice using the conditioned place preference paradigm. Experimental mice were exposed to social defeat in an agonistic encounter before each session of conditioning with 1.25 or 10 mg/kg of MDMA. The effects of social defeat on corticosterone levels and the motor or the anxiogenic effects of MDMA were also evaluated. Mice expose…
Rewarding effects of 3,4-methylenedioxymethamphetamine (“Ecstasy”) in dominant and subordinate OF-1 mice in the place preference conditioning paradigm
2006
We tested the ability of 3,4-methylenedioxymethamphetamine (MDMA) to induce conditioned place preference (CPP) in dominant and subordinate OF-1 mice subjected to cohabitation and repeated sessions of agonistic confrontation, as well as in non-confronted mice. We selected doses of MDMA (2, 6, 10 mg/kg) previously reported to induce CPP in mice and we measured expression of c-Fos evoked by the treatments in non-confronted mice. MDMA induced c-Fos protein in several corticolimbic regions involved in drug-induced reward. Mice were exposed to brief sessions of agonistic confrontation on 5 consecutive days. Determinations of circulating hormones and drug conditioning tests were carried out on com…