Search results for "angle"

showing 10 items of 1921 documents

MMP-2, MMP-9, and iNOS Expression in Human Dental Pulp Subjected to Orthodontic Traction

2009

Abstract Objective: To test the hypothesis that some metalloproteinases (MMP-2, MMP-9) and inducible nitric oxide synthetase (iNOS) enzymes in dental pulp samples do not vary when subjected to orthodontic treatment. Materials and Methods: Human dental pulps were taken from male and female patients (N=10; age 10–14 years). A straight wire technique was used with nickel-titanium or steel archwires. The increase of pressure applied on teeth was gradual. Five patients were subjected to premolar extractions after 14 months of treatment and one after 24 months. Samples were Bouin-fixed, paraffin-embedded, and afterwards processed for immunohistochemistry using anti-MMP-2, anti-MMP-9, and anti-iNO…

MaleSettore BIO/17 - IstologiaTime FactorsNitric oxide synthetaseAdolescentTooth Movement TechniquesNitric Oxide Synthase Type IIDentistryOrthodonticsMalocclusion Angle Class IIMatrix metalloproteinaseNickelFemale patientOrthodontic WiresPressurePremolarHumansMedicineBicuspidChildTitaniumOdontoblastsMMP-2Orthodontic wirebusiness.industrymedicine.diseaseImmunohistochemistryBiomechanical PhenomenaDental pulpiNOSmedicine.anatomical_structureMatrix Metalloproteinase 9SteelMatrix Metalloproteinase 2ImmunohistochemistryFemaleStress MechanicalTreatment timeMalocclusionMMP-9businessImmunohistochemistry Dental pulp MMP-2 MMP-9 iNOS.Dental AlloysFollow-Up StudiesThe Angle Orthodontist
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Bone mineral density of the proximal femur after hip resurfacing arthroplasty: 1-year follow-up study

2011

Abstract Background Hip resurfacing arthroplasty (HRA) is considered a bone-preserving procedure and may eliminate proximal femoral stress shielding and osteolysis. However, in addition to implant-related stress-shielding factors, various patient-related factors may also have an effect on bone mineral density (BMD) of the proximal femur in patients with HRA. Thus, we studied the effects of stem-neck angle, demographic variables, and physical functioning on the BMD of the proximal femur in a one-year follow-up. Methods Thirty three patients (9 females and 24 males) with a mean (SD) age of 55 (9) years were included in the study. BMD was measured two days and 3, 6, and 12 months postoperative…

MaleTime Factorslcsh:Diseases of the musculoskeletal systemBone densityArthroplasty Replacement Hipmedicine.medical_treatmentdual energy X-ray absorptiometry02 engineering and technologySeverity of Illness IndexOsteoarthritis HipAbsorptiometry Photon0302 clinical medicineBone DensityOrthopedics and Sports MedicineFemurProspective StudiesFinlandstress shielding2. Zero hungerBone mineral030222 orthopedicsmedicine.diagnostic_teststem-neck angleMiddle AgedStress shieldingHip resurfacingREPLACEMENTTreatment Outcomemedicine.anatomical_structureFemaleResearch Articlebone remodeling dual energy X-ray absorptiometrymusculoskeletal diseasesmedicine.medical_specialtyeducation0206 medical engineering03 medical and health sciencesFemoral headPOSTERIOR APPROACHRheumatologymedicineHumansFemurPRESERVATIONbone remodelingNECKDual-energy X-ray absorptiometrybusiness.industry3126 Surgery anesthesiology intensive care radiology020601 biomedical engineeringArthroplastySurgeryLogistic Models5-YEARMODESABSORPTIOMETRYFEMORAL-HEADlcsh:RC925-935businessNuclear medicineFollow-Up StudiesBMC Musculoskeletal Disorders
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Direct costs of glaucoma and severity of the disease: a multinational long term study of resource utilisation in Europe

2005

International audience; Background: Resource utilisation and direct costs associated with glaucoma progression in Europe are unknown. As population progressively ages, the economic impact of the disease will increase. Methods: From a total of 1655 consecutive cases, the records of 194 patients were selected and stratified by disease severity. Record selection was based on diagnoses of primary open angle glaucoma, glaucoma suspect, ocular hypertension, or normal tension glaucoma; 5 years minimum follow up were required. Glaucoma severity was assessed using a six stage glaucoma staging system based on static threshold visual field parameters. Resource utilisation data were abstracted from the…

Maleage distributionOrganes des sensgenetic structuresOffice VisitsOcular hypertensionGlaucomaDiseaseintraocular hypertensionSeverity of Illness IndexIndirect costs0302 clinical medicineambulatory careNormal tension glaucomamiddle agedopen angle glaucoma80 and overMedicine030212 general & internal medicinepathophysiologystatistical significanceAged 80 and overeducation.field_of_studyadultdisease coursearticlehealth care costclinical trialHealth Care Costshealth care planningSensory Systems3. Good healthEuropeagedfemalepriority journalstatisticsHealth Resourcesdisease severityadult; aged; article; disease course; disease severity; Europe; female; follow up; general practitioner; glaucoma; health care cost; health care utilization; human; intraocular hypertension; major clinical study; male; medical record; open angle glaucoma; priority journal; statistical significance; visual field; age distribution; ambulatory care; clinical trial; drug cost; economics; health care planning; hospitalization; middle aged; multicenter study; pathophysiology; sex ratio; statistics; utilization review; Adult; Age Distribution; Aged; Aged 80 and over; Drug Costs; Europe; Female; Follow-Up Studies; Glaucoma; Health Care Costs; Health Resources; Humans; Male; Middle Aged; Office Visits; Severity of Illness Index; Sex Distribution; Visual Fieldshospitalizationvisual fieldWorld Viewsmedicine.medical_specialtyOpen angle glaucomadrug costPopulationSensory OrgansMédecine humaine et pathologiemedical recordDrug Costs03 medical and health sciencesCellular and Molecular Neurosciencehealth care utilizationSeverity of illnessfollow upHumanshumanSex Distribution[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organseducationutilization reviewSettore MED/30 - Malattie Apparato Visivobusiness.industryGlaucomaeconomicssex ratiomedicine.diseasemajor clinical studyeye diseasesOphthalmologymulticenter studygeneral practitionerEmergency medicine030221 ophthalmology & optometryOptometryHuman health and pathologyVisual Fieldsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up Studies
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Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma

2009

International audience; Among several theories involved in the pathogenesis of primary open-angle glaucoma (POAG), the vascular theory considers the disease to be a consequence of reduced ocular blood flow associated with red blood cell abnormalities. Red blood cell membrane structure and function are influenced by their phospholipid composition. We investigated whether specific lipid entities that may affect the membrane physiology, namely, polyunsaturated fatty acids (PUFAs) and plasmalogens, are modified in POAG and whether these potential variations are related to the stage of glaucoma. Blood samples were collected from 31 POAG patients and 10 healthy individuals. The stage of glaucoma …

Malegenetic structuresGlaucomaPathogenesischemistry.chemical_compound0302 clinical medicine[SDV.IDA]Life Sciences [q-bio]/Food engineeringETHER-LIPIDSERYTHROCITEchemistry.chemical_classificationAged 80 and over0303 health sciencesMiddle AgedSensory Systemsmedicine.anatomical_structureBiochemistryDocosahexaenoic acidDisease ProgressionFemalelipids (amino acids peptides and proteins)Glaucoma Open-AnglePolyunsaturated fatty acidmedicine.medical_specialtySpectrometry Mass Electrospray IonizationOpen angle glaucomaDocosahexaenoic AcidsPhospholipidBiology03 medical and health sciencesCellular and Molecular NeuroscienceInternal medicinemedicineHumans[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringPLASMALOGENSPRIMARY OPEN-ANGLE GLAUCOMA (POGA)030304 developmental biologyAgedErythrocyte MembraneBlood flowDOCOSAHEXAENOIC ACID (DHA)medicine.diseaseeye diseasesOphthalmologyRed blood cellEndocrinologychemistryCase-Control Studies030221 ophthalmology & optometrysense organsVisual FieldsChromatography Liquid
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Association between a SLC23A2 gene variation, plasma vitamin C levels, and risk of glaucoma in a Mediterranean population

2011

Purpose Several dietary factors have been associated with glaucoma. Among them, dietary antioxidant intake (i.e., vitamin C and vitamin A) in association with glaucoma has been analyzed, but with mixed results. Genetic factors may play a role in modulating the effect of dietary antioxidant intake on glaucoma; however, nutrigenetic studies in this field are scarce. Our aim was to study the association between selected polymorphisms in key proteins related to vitamin C and vitamin A concentrations and primary open-angle glaucoma (POAG). Methods We performed a case-control study matched for age, sex, and bodyweight. We recruited 300 subjects (150 POAG cases and 150 controls) from a Mediterrane…

Malegenetic structuresMediterranean RegionAscorbic AcidPolymorphism Single Nucleotideeye diseasesGenetics PopulationGene FrequencyRisk FactorsCase-Control StudiesHumansFemaleGenetic Predisposition to DiseaseVitamin ASodium-Coupled Vitamin C TransportersGlaucoma Open-AngleResearch ArticleAged
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Serum autoantibodies to alpha-fodrin are present in glaucoma patients from Germany and the United States.

2006

PURPOSE Glaucoma is characterized by a progressive loss of retinal ganglion cells that results in a characteristic optic neuropathy associated with visual field loss. In previous studies, changes in the antibody profiles have been shown in the sera of patients with glaucoma, and these findings suggest a role for autoimmune involvement in the pathogenesis of glaucoma in some patients. The purpose of this study was to compare the antibody profiles against optic nerve antigens in patients with glaucoma in two different study populations from Germany and the United States. METHODS One hundred twenty patients were included in the study, 60 from Germany and 60 from the United States: a control gr…

Malegenetic structuresOpen angle glaucomaBlotting WesternMolecular Sequence DataGlaucomaEnzyme-Linked Immunosorbent AssayNerve Tissue ProteinsRetinal ganglionAutoantigensGas Chromatography-Mass SpectrometryOptic neuropathyAntigenGermanymedicineHumansAmino Acid SequenceEye ProteinsIntraocular PressureAgedAutoantibodiesbusiness.industryMicrofilament ProteinsAutoantibodyMiddle Agedmedicine.diseaseeye diseasesUnited StatesImmunologyOptic nervePopulation studyFemalesense organsbusinessCarrier ProteinsGlaucoma Open-AngleInvestigative ophthalmologyvisual science
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Global electrical heterogeneity as a predictor of cardiovascular mortality in men and women

2018

Aims The aim of this study was to investigate the contribution of depolarization and repolarization abnormalities, specially abnormalities in global electrical heterogeneity of heart in cardiovascular disease (CVD) and all-cause mortality. Methods and results Eight hundred and forty men and 911 women, average age of 63 years participated in this study with average follow-up was 14 years. Six electrocardiogram/vector electrocardiogram (ECG/VECG) markers QRS-duration, QTc-interval, QRST-angle, sum of absolute QRST integral (SAI QRST), T-wave roundness, and TV1-amplitude were estimated from VECG measurements. Hazard ratios (HRs) for CVD events (164 deaths) and all-cause mortality (383 deaths) …

Malekuolleisuusmedicine.medical_specialtyglobal electrical heterogeneityVectorcardiography030204 cardiovascular system & hematologyelectrocardiogramQT intervalRESTING HEART RATERisk Assessment03 medical and health sciencesElectrocardiography0302 clinical medicineSex FactorsRisk Factorscardiovascular diseasecardiovascular mortalityQRST-anglePhysiology (medical)Internal medicinemedicineMale populationRepolarizationHumanscardiovascular diseases030212 general & internal medicineEKGFinlandCardiovascular mortalitybusiness.industryHazard ratiota3142riskitekijätMiddle Agedta3121Confidence intervalElectrophysiological PhenomenaCardiovascular DiseasesRisk stratificationCardiologysydän- ja verisuonitauditFemaleseurantatutkimusCardiology and Cardiovascular MedicinebusinessEuropace
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Study of mandibular growth in patients treated with Frankel s functional regulator (1b)

2012

Objectives: The purpose of this study was to assess mandibular growth in patients with Class II division 1 malocclusions when treated with Fränkel´s functional regulator 1b. Study Design: The treatment group was made up of 43 patients that were divided into two groups: prepubescent (n:28), and pubescent (n:15). The control group included 40 patients who did not receive any kind of treatment and were likewise divided into a prepubescent group (n:19), and a pubescent group (n:21). A computerized cephalometric study was carried out and superimpositions were done in order to assess the antero-posterior, vertical and rotational movements of the mandible. A two-way ANOVA with interaction was done…

Malemedicine.medical_specialtyAdolescentDentistryMandibleMalocclusion Angle Class IIMandibular growthClinical and Experimental DentistrymedicineHumansOrder (group theory)In patientChildGeneral Dentistrybusiness.industryFacial axisMandible:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOrthopedic surgeryOrthodontic Appliances FunctionalResearch-ArticleFemaleSurgeryAnalysis of varianceMalocclusionbusinessMedicina Oral Patología Oral y Cirugia Bucal
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Quantification of topographic changes in the surface of back of young patients monitored for idiopathic scoliosis: correlation with radiographic vari…

2016

Idiopathic scoliosis requires a close follow-up while the patient is skeletally immature to detect early progression. Patients who are monitored by radiographs are exposed to high doses of ionizing radiation. The purpose of this study is to evaluate if an optic noninvasive method of back surface topography based on structured light would be clinically useful in the follow-up of young patients with idiopathic scoliosis. This could reduce the number of radiographs made on these children. Thirty-one patients with idiopathic scoliosis were submitted twice to radiograph and our topographic method at intervals of 6 months to 1 year. Three topographical variables were applied horizontal plane defo…

Malemedicine.medical_specialtyAdolescentRadiographyBiomedical EngineeringIdiopathic scoliosisScoliosisBiomaterialsCorrelation03 medical and health sciencesUser-Computer Interface0302 clinical medicineImage Interpretation Computer-AssistedDeformitymedicinePhotographyHumansChild030222 orthopedicsBackCobb anglebusiness.industrymedicine.diseaseTrunkAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsSurgeryRadiographyScoliosisFemalemedicine.symptombusinessNuclear medicine030217 neurology & neurosurgerySymmetry indexJournal of biomedical optics
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Cytokine expression in tears of patients with glaucoma or dry eye disease: A prospective, observational cohort study.

2018

Background: The aim of this study was to assess the expression of cytokines/chemokines in tears from patients with non-advanced primary open-angle glaucoma and patients with non-severe dry eye disease versus healthy controls. Methods: This prospective, observational cohort study enrolled patients with confirmed or suspected non-advanced primary open-angle glaucoma who received any prostaglandin analogue monotherapy for longer than 6 months, patients with non-severe dry eye disease, and healthy controls. Expression of interleukin-1β, interleukin-2, interleukin-4, interleukin-5, interleukin-6, interleukin-8, interleukin-10, and interleukin-12; tumor necrosis factor α; vascular endothelial gro…

Malemedicine.medical_specialtyChemokineGlaucomaInflammationDiseaseCohort Studies03 medical and health sciences0302 clinical medicineOphthalmologymedicineHumansProspective StudiesEye ProteinsAntihypertensive AgentsIntraocular PressureAgedbiologybusiness.industryPreservatives PharmaceuticalCytokine expressionGeneral MedicineMiddle Agedmedicine.diseaseOphthalmologyTears030221 ophthalmology & optometrybiology.proteinTearsCytokinesDry Eye SyndromesFemalemedicine.symptomOphthalmic Solutionsbusiness030217 neurology & neurosurgeryGlaucoma Open-AngleCohort studyEuropean journal of ophthalmology
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