Search results for "appetite"
showing 10 items of 66 documents
Le petit mangeur âgé
2019
National audience
La nutrition des personnes âgées : l'affaire de tous !
2019
National audience
Review article: a comparison of glucagon-like peptides 1 and 2.
2013
Summary Background Recent advancements in understanding the roles and functions of glucagon-like peptide 1 (GLP-1) and 2 (GLP-2) have provided a basis for targeting these peptides in therapeutic strategies. Aim To summarise the preclinical and clinical research supporting the discovery of new therapeutic molecules targeting GLP-1 and GLP-2. Methods This review is based on a comprehensive PubMed search, representing literature published during the past 30 years related to GLP-1 and GLP-2. Results Although produced and secreted together primarily from L cells of the intestine in response to ingestion of nutrients, GLP-1 and GLP-2 exhibit distinctive biological functions that are governed by t…
Evolution des préférences et des répertoires alimentaires avec l'âge
2018
National audience
Grand âge et petit appétit
2018
National audience
Appetite and Obesity
2011
Orexin (hypocretin) plays an important role in promoting wakefulness [1]. It stimulates wakefulness when injected in the cerebral ventricles, in the periventricular nucleus, dorsomedial hypothalamus, or lateral hypothalamus [2, 3]. Orexinergic neurons originate from the lateral hypothalamus and have projections to most parts of the central nervous system including the brain stem. The lack of orexin and/or orexin receptors is linked to narcolepsy [4–6].
Postnatal Overfeeding in Rodents by Litter Size Reduction Induces Major Short- and Long-Term Pathophysiological Consequences
2013
Numerous studies have demonstrated that the early postnatal environment can influence body weight and energy homeostasis into adulthood. Rodents raised in small litters have been shown to be a useful experimental model to study the short- and long-term consequences of early overnutrition, which can lead to modifications not only in body weight but also of several metabolic features. Postnatal overfeeding (PNOF) induces early malprogramming of the hypothalamic system, inducing acquired persisting central leptin and insulin resistance and an increase in orexigenic signals. Visceral white adipose tissue, lipogenic activity, and inflammatory status are increased in PNOF rodents, while brown adi…
Discrepancy between food offered and consumed during hospitalization in older adult patients
2020
AbstractMalnutrition is one of the most frequent geriatric syndromes and a key contributor to frailty. Ageing is commonly associated with modifications in eating habits with changes in appetite and food intake. Malnutrition is not only a sign of illness, but its presence increases morbidity, hospital stay, institutionalization, poor quality of life, in-hospital complications, expenses, and mortality. Hospitalized patients have increased calorie requirements to overcome the increased energy expenditure due to acute disease. We aimed to evaluate the actual consumption of the food offered to a sample of hospitalized older adults. Sixty hospitalized patients (women/men = 23/37) were recruited s…
En EHPAD, repérer les petits mangeurs et adapter leur alimentation : quel coût, quel bénéfice ?
2018
National audience; Des pesées alimentaires ont montré qu'une large majorité de personnes âgées vivant en EHPAD (Etablissement d'Hébergement pour Personne Âgée Dépendante) ne mange pas suffisamment pour couvrir ses besoins nutritionnels. Il s'ensuit un coût pour les personnes elles-mêmes (augmentation du risque nutritionnel), ainsi qu'un coût pour l'environnement (gaspillage alimentaire). Dans ce contexte, l'objectif de RENESSENS était de proposer aux résidents d'EHPAD une offre alimentaire adaptée à leurs capacités d'ingestion afin de couvrir leurs besoins nutritionnels. Pour cela, nous avons réalisé une étude clinique de 6 mois dans deux maisons de retraite, l'une contrôle (n=43) et l'autr…
A common biological basis of obesity and nicotine addiction
2013
Contains fulltext : 128630.pdf (Publisher’s version ) (Open Access) Smoking influences body weight such that smokers weigh less than non-smokers and smoking cessation often leads to weight increase. The relationship between body weight and smoking is partly explained by the effect of nicotine on appetite and metabolism. However, the brain reward system is involved in the control of the intake of both food and tobacco. We evaluated the effect of single-nucleotide polymorphisms (SNPs) affecting body mass index (BMI) on smoking behavior, and tested the 32 SNPs identified in a meta-analysis for association with two smoking phenotypes, smoking initiation (SI) and the number of cigarettes smoked …