Search results for "arthritis"

showing 10 items of 1029 documents

Experienced health in older women with rheumatoid arthritis.

2007

ABSTRACT This study explored how older women with chronic illness and disability experience their own health. Data were collected in in-depth interviews with ten older women with rheumatoid arthritis. Data analysis and interpretation was carried out within a phenomenological-hermeneutic frame of understanding, which revealed five major themes: health as coping with everyday life, health as freedom, health as absence of inconvenience, health as togetherness and health as mental well-being. For older people with chronic illness and disability, good health found expression in general well-being. It was perceived as a state of equilibrium that the respondents sought to maintain through their ow…

Coping (psychology)medicine.medical_specialtyHealth BehaviorGender StudiesArthritis RheumatoidSurveys and QuestionnairesActivities of Daily LivingAdaptation PsychologicalmedicineHumansEveryday lifePsychiatrySelf-rated healthAgedbusiness.industryFocus GroupsMiddle Agedmedicine.diseaseUnited StatesSelf-Help GroupsRheumatoid arthritisQuality of LifeWomen's HealthFemaleGeriatrics and GerontologyOlder peoplebusinessJournal of womenaging
researchProduct

Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in…

2021

Abstract Background There is mounting evidence on the existence of a Pediatric Inflammatory Multisystem Syndrome-temporally associated to SARS-CoV-2 infection (PIMS-TS), sharing similarities with Kawasaki Disease (KD). The main outcome of the study were to better characterize the clinical features and the treatment response of PIMS-TS and to explore its relationship with KD determining whether KD and PIMS are two distinct entities. Methods The Rheumatology Study Group of the Italian Pediatric Society launched a survey to enroll patients diagnosed with KD (Kawasaki Disease Group – KDG) or KD-like (Kawacovid Group - KCG) disease between February 1st 2020, and May 31st 2020. Demographic, clini…

Coronary artery abnormalities; Hypotension; Kawasaki disease; Multisystem inflammatory syndrome associated with coronavirus disease; Myocarditis; Pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection; SARS-CoV-2; Age Distribution; Antirheumatic Agents; Aspirin; C-Reactive Protein; COVID-19; Child; Child Preschool; Coronary Artery Disease; Cough; Diarrhea; Dyspnea; Female; Glucocorticoids; Heart Failure; Humans; Hyperferritinemia; Hypotension; Immunoglobulins Intravenous; Immunologic Factors; Infant; Intensive Care Units Pediatric; Interleukin 1 Receptor Antagonist Protein; Italy; Lymphopenia; Male; Mucocutaneous Lymph Node Syndrome; Myocarditis; Platelet Aggregation Inhibitors; SARS-CoV-2; Shock; Systemic Inflammatory Response Syndrome; Tachypnea; Troponin T; VomitingMalelcsh:Diseases of the musculoskeletal systemcoronary artery abnormalities; hypotension; kawasaki disease; multisystem inflammatory syndrome associated with coronavirus disease; myocarditis; pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection; SARS-CoV-2; age distribution; antirheumatic agents; aspirin; C-reactive protein; COVID-19; child ; preschool; coronary artery disease; cough; diarrhea; yspnea; female; glucocorticoids; heart failure; humans; hyperferritinemia; hypotension; immunoglobulins; intravenous; immunologic factors; infant; intensive care units; pediatric; interleukin 1 receptor antagonist protein; italy; lymphopenia; male; mucocutaneous lymph node syndrome; myocarditis; platelet aggregation inhibitors; SARS-CoV-2; shock; systemic inflammatory response syndrome; tachypnea; troponin T; vomitingMyocarditiCoronary Artery Disease030204 cardiovascular system & hematologySARS-CoV-2 Kawasaki disease Pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection Myocarditis Hypotension Multisystem inflammatory syndrome associated with coronavirus disease Coronary artery abnormalitiesCoronary artery diseaseSettore MED/38 - Pediatria Generale E Specialistica0302 clinical medicineGlucocorticoidImmunologic FactorMultisystem inflammatory syndrome associated with coronavirus diseaseImmunology and AllergyChildCoronary artery abnormalitieFisher's exact testPediatricTachypneabiologylcsh:RJ1-570Antirheumatic AgentImmunoglobulins IntravenousShockPediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infectionSettore MED/38Systemic Inflammatory Response SyndromeIntensive Care UnitsMyocarditisC-Reactive ProteinItalyAntirheumatic AgentsChild PreschoolCohortsymbolsPlatelet aggregation inhibitorFemaleHypotensionIntravenousCoronary artery abnormalitiesHumanResearch ArticleDiarrheamedicine.medical_specialtyMyocarditisVomitingImmunoglobulinsMucocutaneous Lymph Node SyndromeIntensive Care Units Pediatric03 medical and health sciencessymbols.namesakeAge DistributionRheumatologyTroponin TInternal medicineLymphopeniamedicineHumansImmunologic FactorsPreschoolGlucocorticoids030203 arthritis & rheumatologyHeart FailureAspirinKawasaki diseasebusiness.industrySARS-CoV-2Platelet Aggregation InhibitorC-reactive proteinCOVID-19Infantlcsh:Pediatricsmedicine.diseaseSystemic inflammatory response syndromeInterleukin 1 Receptor Antagonist ProteinDyspneaCoughImmunoglobulins IntravenouPediatrics Perinatology and Child Healthbiology.proteinKawasaki diseaseHyperferritinemialcsh:RC925-935businessPlatelet Aggregation InhibitorsPediatric rheumatology online journal
researchProduct

Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020

Abstract Background Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety. Methods MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020. Results We identified 3 indirect pre-clinical studies and 28 clinical studies including 5776 patients with COVID-19 (13 with a comparison group,…

Coronavirus COVID-19 Pneumonia SARS-CoV-2 TocilizumabGCA Giant cell arteritispJIA Pediatric juvenile idiopathic arthritislaw.inventionchemistry.chemical_compound0302 clinical medicineRandomized controlled triallawMedicine030212 general & internal medicineClinical efficacyCPAP Continuous positive airway pressureCOVID-19 Coronavirus disease 2019IDSA Infectious Diseases Society of AmericaRA Rheumatoid arthritisTocilizumabIMV Invasive mechanical ventilationsJIA Juvenile idiopathic arthritisAIFA Agenzia Italiana del FarmacoPulmonary and Respiratory Medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEAntibodies Monoclonal HumanizedNIH U.S. National Institutes of HealthArticleWHO World Health OrganizationSIMIT Italian Society of Infectious and Tropical disease03 medical and health sciencesTocilizumabARDS Acute respiratory distress syndromeAnimalsHumansIn patientIntensive care medicineTocilizumab ; COVID-19 ; Pneumonia ; SARS-CoV-2 ; Coronaviruslcsh:RC705-779business.industryCRS CAR-T cell-induced cytokine release syndromeInterleukin-6SARS-CoV-2NIV Noninvasive mechanical ventilationTNF Tumor necrosis factorCOVID-19Pneumonialcsh:Diseases of the respiratory systemCOVID-19 Drug TreatmentClinical trialCoronavirus030228 respiratory systemchemistrybusinessICTRP International Clinical Trials Registry PlatformPulmonology
researchProduct

Knowledge expectations of recently diagnosed patients with knee osteoarthritis.

2016

Aim The aim of this study was to assess the socio-demographic and disease-related symptoms and emotions and knowledge expectations of patients recently diagnosed with knee osteoarthritis. A further aim was to determine associations between selected demographic variables and patients' expected knowledge. Background Patient counselling and information provision are recommended for all patients with knee osteoarthritis. In healthcare centres, there is a good possibility to establish the knowledge expectations of patients with knee osteoarthritis during counselling. Recent empirical evidence indicates a lack of research on knowledge expectations among recently diagnosed patients with knee osteo…

CounselingMalemedicine.medical_specialtyHigher educationEmotionsempowering knowledgeOsteoarthritisknee osteoarthritisHospital Patient's Knowledge Expectations Scale03 medical and health sciences0302 clinical medicinenursingPatient Education as TopicSurveys and QuestionnairesHealth careMedicineHumans030212 general & internal medicineHospital patientsEmpirical evidenceGeneral NursingAged030203 arthritis & rheumatologybusiness.industryta3141Pain managementMiddle AgedOsteoarthritis Kneemedicine.diseaseKnowledgePatient SatisfactionVocational educationScale (social sciences)Physical therapysymptomsFemalebusinessJournal of advanced nursing
researchProduct

Psychometric properties of the French translation of the reduced KOOS and HOOS (KOOS-PS and HOOS-PS).

2009

Udgivelsesdato: 2009-Dec OBJECTIVE: To evaluate the psychometric properties of the French KOOS physical function (KOOS-PS) and HOOS physical function (HOOS-PS), specifically its feasibility, reliability, construct validity, and responsiveness. METHODS: Consecutive outpatients consulting for primary knee or hip osteoarthritis (OA) in a rheumatology department were included. During the initial assessment, patients were asked to complete the Knee injury and Osteoarthritis Outcome Score (KOOS) or Hip disability and Osteoarthritis Outcome Score (HOOS) questionnaire and the OsteoArthritis Knee and Hip Quality Of Life questionnaire (OAKHQOL). The patients were given a second KOOS or HOOS questionn…

Cross-Cultural ComparisonMalemedicine.medical_specialtyPsychometricsPsychometricsBiomedical EngineeringOsteoarthritisOARSISeverity of Illness IndexOsteoarthritis HipValidityDisability EvaluationPhysical medicine and rehabilitationQuality of lifeRheumatologySurveys and QuestionnairesFunctional evaluationSeverity of illnessActivities of Daily LivingmedicineHip osteoarthritisHumansHip osteoarthritisOrthopedics and Sports MedicineHOOS-PSAgedPain MeasurementHip surgeryCross-cultural adaptationbusiness.industryOMERACTConstruct validityResponsivenessOsteoarthritis KneeKOOS-PSReliabilitymedicine.diseaseTreatment OutcomePhysical therapyQuality of LifeCeiling effectFeasibility StudiesFemaleKnee osteoarthritisbusinessOsteoarthritis and cartilage
researchProduct

Multi-language translation and cross-cultural adaptation of the OARSI/OMERACT measure of intermittent and constant osteoarthritis pain (ICOAP).

2009

Summary Aim To conduct a multi-language translation and cross-cultural adaptation of the Intermittent and Constant OsteoArthritis Pain (ICOAP) questionnaire for hip and knee osteoarthritis (OA). Methods The questionnaires were translated and cross-culturally adapted in parallel, using a common protocol, into the following languages: Czech, Dutch, French (France), German, Italian, Norwegian, Spanish (Castillan), North and Central American Spanish, Swedish. The process was conducted following five steps: (1) – independent translation into the target language by two or three persons; (2) – consensus meeting to obtain a single preliminary translated version; (3) – backward translation by an ind…

CzechCross-Cultural Comparisonmedicine.medical_specialtyBiomedical EngineeringMEDLINEOsteoarthritisNorwegianKnee – Pain – ICOAP – TranslationOsteoarthritis HipGermanConstant (computer programming)Hip – osteoarthritisRheumatologySurveys and QuestionnairesOsteoarthritismedicineCross-culturalHumansOrthopedics and Sports MedicineTranslationsLanguagePain Measurementbusiness.industryOsteoarthritis Kneemedicine.diseaseCross-cultural studieslanguage.human_languagelanguagePhysical therapybusinessOsteoarthritis and cartilage
researchProduct

Selective, Highly Sensitive, and Rapid Detection of Genomic DNA by Using Gated Materials:MycoplasmaDetection

2013

The coupling of gated-indicator delivery with highly specific biochemical recognition is an innovative strategy for the detection of DNA sequences, able to compete with classical methods which need PCR amplification, in important areas such as point-of-care diagnostics or detection of specific biological contaminations with pathogens. Such comparatively simple and cheap yet highly selective and sensitive assays hold promise for use in less-developed areas of the world.

DNA BacterialINGENIERIA DE LA CONSTRUCCIONSupportsMesoporous silica nanoparticlesFermentansResponsive controlled releaseAmplificationmesoporous materialsBiologysensorsmedicine.disease_causeRapid detectionCatalysisgated materialschemistry.chemical_compoundMycoplasmaQUIMICA ORGANICAContaminationQUIMICA ANALITICABIOQUIMICA Y BIOLOGIA MOLECULARmedicineGated materialsRheumatoid arthritismycoplasmaControlled drug deliverySensorsQUIMICA INORGANICAGenomicsDNAGeneral ChemistryMycoplasmaCell culturesMolecular biologyHighly sensitivegenomic DNAchemistryDNAAngewandte Chemie International Edition
researchProduct

Relationship between lower limb neuromuscular performance and bone strength in postmenopausal women with mild knee osteoarthritis.

2014

Objectives: To investigate whether neuromuscular performance predicts lower limb bone strength in different lower limb sites in postmenopausal women with mild knee osteoarthritis (OA). Methods: Neuromuscular performance of 139 volunteer women aged 50-68 with mild knee OA was measured using maximal counter movement jump test, isometric knee flexion and extension force and figure-of-eight-running test. Femoral neck section modulus (Z, mm³) was determined by data obtained from dualenergy X-ray absorptiometry. Data obtained using peripheral quantitative computed tomography was used to asses distal tibia compressive (BSId, g2/cm4) and tibial mid-shaft bending (SSImaxmid, mm3) strength indices. R…

DXAnivelrikkoNeuromuscular PerformanceCompressive StrengthTibianeuromuskulaarinen suorituskykyMiddle AgedOsteoarthritis KneeBone StrengthPQCTPostmenopauseAbsorptiometry PhotonOsteoarthritisluun lujuusHumansFemaleTomography X-Ray ComputedPsychomotor PerformanceAgedJournal of musculoskeletalneuronal interactions
researchProduct

Effects of one year of training with elastic bands on the pain in menopausal women

2018

Antecedentes y objetivos: En la literatura, la relación entre el entrenamiento de la fuerza con banda elástica, la proteína C reactiva y el dolor musculoesquelético en mujeres posmenopáusicas aún no está claro. El objetivo del presente estudio fue investigar los efectos de un año de entrenamiento de resistencia progresiva con bandas elásticas en los parámetros de la proteína C reactiva, el dolor y la composición corporal en mujeres posmenopáusicas. Población: Mujeres posmenopáusicas sedentarias (> 12 meses de amenorrea). Método: Cuarenta mujeres realizaron un entrenamiento de resistencia progresivo durante 12 meses (6 ejercicios para todo el cuerpo, 3 series x 10 repeticiones y la intensida…

Dolor musculoesquelético030203 arthritis & rheumatologyMusculoskeletal painPhysical Therapy Sports Therapy and RehabilitationEjercicioResistance trainingC-reactive protein03 medical and health sciences0302 clinical medicineEntrenamiento de resistenciaEducación Física y DeportivaProteína C reactiva030212 general & internal medicineExerciseFisioterapia
researchProduct

Highly purified chondroitin sulfate: a literature review on clinical efficacy and pharmacoeconomic aspects in osteoarthritis treatment

2020

AbstractOsteoarthritis (OA) is the most prevalent musculoskeletal disease and a major cause of negative relevant outcomes, associated with an ever-increasing societal burden. Pharmaceutical-grade chondroitin sulfate (CS) was repeatedly reported to reduce pain and improve function in patients with OA. This article aims to review the evidence for the role of highly purified (hp) CS (Condrosulf®, IBSA) in the treatment of OA. We collected and reported evidence concerning (1) efficacy of hpCS 800 mg/day in the treatment of OA affecting the knee, hand and hip; (2) efficacy and safety of hpCS 1200 mg/day also in the oral gel formulation; (3) the safety profile of hpCS; (4) the difference of hpCS …

DrugAgingmedicine.medical_specialtyChondroitin sulfateKnee Jointmedia_common.quotation_subjectChondroitin sulfate · Osteoarthritis · Knee osteoarthritis · Hip osteoarthritis · Hand osteoarthritis · Economic analysisOsteoarthritisReviewChondroitin sulfate A03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineOsteoarthritisHand osteoarthritismedicineHumansIn patientHip osteoarthritis030212 general & internal medicineClinical efficacyChondroitin sulfateEconomics Pharmaceuticalmedia_common030203 arthritis & rheumatologybusiness.industryAnti-Inflammatory Agents Non-SteroidalChondroitin SulfatesEconomic analysisMusculoskeletal diseaseOsteoarthritis Kneemedicine.diseaseSafety profileTreatment Outcomechemistryembryonic structuresKnee osteoarthritisGeriatrics and Gerontologybusiness
researchProduct