Search results for "arvo"

Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery

2019

Parvoviruses are an important platform for gene and cancer therapy. Their cell entry and the following steps, including nuclear import, are inefficient, limiting their use in therapeutic applications. Two models exist on parvoviral nuclear entry: the classical import of the viral capsid using nuclear transport receptors of the importin (karyopherin) family or the direct attachment of the capsid to the nuclear pore complex leading to the local disintegration of the nuclear envelope. Here, by laser scanning confocal microscopy and in situ proximity ligation analyses combined with coimmunoprecipitation, we show that infection requires importin β-mediated access to the nuclear pore complex and …

Tukea tarvitsevista ja siitä riippuvaisista

2018

Modernin draaman klassikko

2017

Arvostelu teoksesta August Strindberg: Neiti Julie, naturalistinen murhenäytelmä, suom. Helena Anhava, 1988. nonPeerReviewed

From Efficiency to Resilience : Systemic Change towards Sustainability after the COVID-19 Pandemic

2021

The COVID-19 pandemic has revealed the vulnerability of current socio-economic systems and thrown into question the dominant global paradigm geared towards short-term financial efficiency. Although it has been acknowledged for several decades that this paradigm has detrimental impacts on the climate, the environment and global welfare, the pandemic has now offered a grim ‘rehearsal round’ for more serious crises that are to come with the accelerating climate emergency, loss of biodiversity and growing human inequalities. Along with worsening climate change, there are looming risks for mass migrations and armed conflicts as habitats capable of supporting human wellbeing become scarce, such a…

Book Reviews : Raymond Williams on culture and society: essential writings

2015

Kaivattu kokonaisesitys Kiinan historiasta

2019

Approaches on gender equality in development cooperation : a comparison between the international, national and project levels

2004

Sitaattien niukoista saloista joukkoistetuksi sitaattiverkkopankiksi?

2016

Cultural Values’ Influences on Users’ Preferences for Gamification Techniques

2019

Gamification techniques such as badges, levels, roles, are widely adopted in information systems (IS). Though researchers have noted that cultural values may influence users' usage of IS, there is a lack of research regarding the relationship of cultural values and gamification techniques. Our study aims to contribute to this area. We propose that users' cultural values may influence how they are motivated and further influence their preferences toward specific gamification techniques. In this research in progress, we review cultural values, examine the currently adopted gamification techniques, and then propose how cultural values influence users' preferences toward specific gamification t…

Clinical presentation and outcome of 20 fetuses with parvovirus B19 infection complicated by severe anemia and/or fetal hydrops

2014

Aim The aim of this study was to assess the prognosis of parvovirus B19 infection with severely anemic and/or hydropic fetuses according to initial ultrasound and biological criteria. Material and methods Retrospective study of 20 cases of congenital parvovirus B19-proven infection (positive PCR) complicated by fetal anemia and/or hydrops was examined. Anemia was suspected on an elevated peak systolic velocity of the middle cerebral artery and was confirmed by fetal blood sampling. Results Survival rate was 70% (14/20) overall and 76% (13/17) for fetuses with one or more transfusions. When fetal effusion regressed after the transfusion, all 11 fetuses survived, and neonatal condition was fa…