Search results for "attention deficit hyperactivity disorder"
showing 10 items of 166 documents
Evidence for shared environmental contributions to attention-deficit/hyperactivity traits. A twin study
2019
Background and objectives: Behavior-genetic analyses have shown that measurements of inattention and hyperactivity-impulsivity are genetically-influenced. In view of limited studies on ADHD (Attention deficit hyperactivity disorder) in Spanish samples, this study aims to explore the genetic architecture of ADHD symptoms; inattention and hyperactivity-impulsivity in a Spanish twin schoolchildren sample. Methods: Participants were 258 pairs of adolescent Spanish twins. Symptoms of ADHD, inattention and hyperactivity-impulsivity were assessed by means of a sub-scale of the Strengths and Difficulties Questionnaire. Univariate twin models, according to sex, were run to assess the heritability of…
Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder
2008
Contains fulltext : 69243.pdf (Publisher’s version ) (Closed access) Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (P(S…
No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder.
2008
Contains fulltext : 71091.pdf (Publisher’s version ) (Closed access) Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for association between the long-allele of a 44-bp insertion/deletion polymorphism (5-HTTLPR) and ADHD. Another two studies corroborated this finding while a further six studies did not find such an association. For a second polymorphism within the gene, a variable number tandem repeat (VNTR) within intron 2, one study demonstrated that the 12/12 genotype was significantly less frequent in ADHD cases compared to controls, while a sec…
Dictating the boundaries of ab/normality: a critical discourse analysis of the diagnostic criteria for attention deficit hyperactivity disorder and h…
2017
In this article we report the findings of a critical discourse analysis of the diagnostic criteria for attention deficit hyperactivity disorder (ADHD) and hyperkinetic disorder (HD) in two clinical manuals – Diagnostic and Statistical Manual of Mental Disorders, 5th edition and International Classification of Diseases, 10th edition. We examine the actions (behaviors) that are said to indicate the presence of ADHD/HD and analyze what the inclusion of these actions reveals about the relationship between ADHD/HD, cultural knowledge, and values. Our analysis reveals that both manuals use subjective, value-laden language to construct a mentally ill individual in opposition to an unseen, supposed…
Dyscalculia: Clinical manifestations, evaluation and diagnosis. Current Perspectives of educational intervention
2019
Learning difficulties and learning disorders are very frequent in schools nowadays, and they have been increasing in the field of mathematics. Such difficulties tend to be associated with other disorders such as dyslexia or Attention Deficit Hyperactivity Disorder (ADHD). The present article aims at deepening our understanding, definition and detection of dyscalculia, along with reviewing current educational treatments. Since 1990, concerns about learning difficulties in the classroom have been made explicit in policies such as the Spanish Law on the General Ordering of the Education System (LOGSE). Likewise, the indicators, symptoms, and prevalence of dyscalculia have been gathered since t…
Learning to Teach Students With Attention Deficit Hyperactivity Disorder
2018
The presence of special needs students in regular classrooms makes it difficult for teachers to manage the situation, especially since in Romania the initial teacher-training curriculum doesn't include a class addressing the issue. This chapter talks about the teaching, learning, and evaluation experiences offered by an instructional unit on the subject of ADHD for over 700 primary and secondary school teachers from all areas of expertise. The purpose of this unit was to increase the teachers' knowledge and understanding of students with attention deficit hyperactivity disorder (ADHD) in an educational frame. This chapter presents content elements, learning, and assessment activities that t…
Written composition performance of students with attention-deficit/hyperactivity disorder
2011
ABSTRACTAttention-deficit/hyperactivity disorder (ADHD) is frequently associated with learning disabilities. The present study examined the written composition of children with ADHD, which depends to a large degree on continuous self-regulation and attentional control skills for organizing information and maintaining the level of effort. Fifty children with ADHD and 50 normally developing children, matched on age and IQ, were assessed using a composition writing task. The results contribute to prior research findings by showing that the children with ADHD performed significantly worse than the comparison groups on the majority of the planning, translation, and revision process measures usua…
Exposure to mercury among 9-year-old children and neurobehavioural function
2021
Abstract Mercury (Hg) is an environmental neurotoxicant whose main route of exposure in humans is the consumption of seafood. The aim of this study was to explore the relationship between Hg exposure at 9 years old and behaviour assessed at 9 and 11 years old. Study subjects were mother–child pairs participating in the INMA (Environment and Childhood) Project in Valencia (Spain). Total Hg (THg) was measured in hair samples from the children at 9 years old. Behaviour and emotions were assessed at 9 (n = 472) years and 11 (n = 385) years of age using the Child Behaviour Checklist test (CBCL) and the Conners Parents Rating Scale-Revised: Short Form (CPRS-R:S). Furthermore, the attention functi…
Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
2017
International audience; Gain-of-function mutations in some genes underlie neurodegenerative conditions, whereas loss-of-function mutations in the same genes have distinct phenotypes. This appears to be the case with the protein ataxin 1 (ATXN1), which forms a transcriptional repressor complex with capicua (CIC). Gain of function of the complex leads to neurodegeneration, but ATXN1-CIC is also essential for survival. We set out to understand the functions of the ATXN1-CIC complex in the developing forebrain and found that losing this complex results in hyperactivity, impaired learning and memory, and abnormal maturation and maintenance of upper-layer cortical neurons. We also found that CIC …
Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attent…
2009
Contains fulltext : 80906.pdf (Publisher’s version ) (Closed access) BACKGROUND: Mothers' positive emotions expressed about their children with attention deficit/hyperactivity disorder (ADHD) are associated with a reduced likelihood of comorbid conduct problems (CP). We examined whether this association with CP, and one with emotional problems (EMO), is moderated by variants within three genes, previously reported to be associated with ADHD and to moderate the impact of environmental risks on conduct and/or emotional problems; the dopamine transporter gene (SLC6A3/DAT1), the dopamine D4 receptor gene (DRD4) and the serotonin transporter gene (SLC6A4/5HTT). METHODS: Seven hundred and twenty-…