Search results for "bile"

GLOBALE/locale. Il ruolo delle istituzioni

2008

Porphyrin-bile acid conjugates: from saccharide recognition in the solution to the selective cancer cell fluorescence detection.

2008

This paper describes the preparation and use of conjugates of porphyrins and bile acids as ligands to bind to tumor expressed saccharides. Bile acid-porphyrin conjugates were tested for recognition of saccharides that are typically present on malignant tumor cells. Fluorescence microscopy, in vitro PDT cell killing, and PDT of subcutaneous 4T1 mouse tumors is reported. High selectivity for saccharide cancer markers and cancer cells was observed. This in vivo and in vitro study demonstrated high potential use for these compounds in targeted photodynamic therapy.

Assessment of mobile phoneapplications feasibility on plant recognition: comparison with Google Lens AR-app

2020

The paper is devoted to systemizing all mobile applications used during the STEM-classes and can be used to identify plants. There are 10 mobile applications that are plant identifiers worldwide. These applications can be divided into three groups, such as plant identifiers that can analyze photos, plant classification provides the possibility to identify plants manually, plants-care apps that remind water of the plant, or change the soil. In this work, mobile apps such as Flora Incognita, PlantNet, PlantSnap, PictureThis, LeafSnap, Seek, PlantNet were analyzed for usability parameters and accuracy of identification. To provide usability analysis, a survey of experts of digital education on…

Metabolomics discloses donor liver biomarkers associated with early allograft dysfunction

2014

Background & Aims Early allograft dysfunction (EAD) dramatically influences graft and patient outcome after orthotopic liver transplantation and its incidence is strongly determined by donor liver quality. Nevertheless, objective biomarkers, which can assess graft quality and anticipate organ function, are still lacking. This study aims to investigate whether there is a preoperative donor liver metabolomic biosignature associated with EAD. Methods A comprehensive metabolomic profiling of 124 donor liver biopsies collected before transplantation was performed by mass spectrometry coupled to liquid chromatography. Donor liver grafts were classified into two groups: showing EAD and immediate g…

A mobile game as a support tool for children with severe difficulties in reading and spelling

2020

We used a randomized controlled trial to investigate if a mobile game, GraphoLearn (GL), could effectively support the learning of first graders (N = 70), who have severe difficulties in reading and spelling. We studied the effects of two versions of the game: GL Reading, which focused on training letter-sound correspondence and word reading; and GL Spelling, which included additional training in phonological skills and spelling. During the spring of first grade, the children trained with tablet computers which they could carry with them during the six-week intervention. The average exposure time to training was 5 hr 44 min. The results revealed no differences in the development of reading …

Tierexperimentelle Untersuchungen zum gestielten D�nndarm-transplantat als partieller extrahepatischer Gallengangsersatz

1991

Mit einem gestielten Dunndarmpatch konnte in Einzelfallen eine Gallengangsstriktur dauerhaft erweitert werden. Man beobachtet jedoch eine Dilatation des Patches, deren Ursache ebenso wie deren Folgen auf die Leberfunktion bislang ungeklart sind. Mit einem gestielten Dunndarmpatch ist tierexperimentell ein partieller extrahepatischer Gallengangsersatz moglich. Eine Erweiterung des Patches wird regelmasig beobachlet. Ursache hierfur ist weder eine Denervation des Patches noch der intraduktale Gallengangsdruck, sondern moglicherweise ein Zug am Gefasstiel. Morphologische Veranderungen treten am Patch nach bis zu 15 Monaten nicht auf. Leberfunktionsstorungen konnen weder laborchemisch noch hist…

Immunohistochemical Characterization of 130 Cases of Primary Hepatic Carcinomas

1987

Primary liver carcinoma (PLC) may express a certain number of markers. Here we communicate results of an analysis of five such markers (alpha-1-antitrypsin--AAT--, carcino-embryonic antigen --CEA--, alpha-fetoprotein --AFP--, and superficial --HBsAg-- and core --HBcAg-- antigens of hepatitis B virus) by means of PAP techniques in 130 cases of PLC, comparing the neoplastic tissue and the non-tumorous liver. Three variants of PLC are distinguished: hepatocarcinoma (HC) (108 cases); cholangiocarcinoma (CC) (19 cases); and three cases of hepatocholangiocarcinoma (HCC). AAT was positive in 29 HC, 2 HCC, and negative in all 19 CC. CEA appeared positive in 16 HC, 16 CC and only one HCC. AFP was po…

Protection of Patient Data in Digital Oral and General Health Care: A Scoping Review with Respect to the Current Regulations

2023

The use of digital health technologies, including telemedicine and teledentistry, has become a necessity in healthcare due to the SARS-CoV-19 pandemic. These technologies allow for the reduction of the workload of healthcare providers and the improvement of patient outcomes in cases of remote monitoring, diagnosis, and communication. While there are no doubtful benefits, there are some counterparts, such as concerns about clinical risks, data security, and privacy protection. This paper aims to review the regulations regarding the use of digital health apps and software in healthcare. This scoping review followed the PRISMA-ScR guidelines and the five-step framework of Arksey and O’Malley. …

Reconsidérer les mobilités quotidiennes en prenant en compte les habitudes individuelles

2019

Depuis quelques années, on constate dans la littérature un regain d’intérêt pour une analyse des habitudes lorsqu’elles concernent les mobilités quotidiennes (Brette et al., 2014 ; Schwanen et al., 2012). Par « habitude » il faut comprendre non pas la simple répétition de trajets, mais bel et bien un ensemble de savoir-faire acquis par l’expérience ou par l’éducation (Kaufmann, 2001). Par exemple, une personne ayant une forte habitude automobile, a tendance à automatiser (d’un point de vue cognitif) de plus en plus ses trajets quotidiens, à s’en détacher, pour associer à ses déplacements des activités plus ou moins « productives » (ex : envoyer des mails, des messages, téléphoner, regarder …

Handover management in heterogenous mobile and wireless networks

2015

Since 1990, networking and mobile technologies have made a phenomenal unprecedented progress. This progress has been experienced on multiple fronts in parallel; especially on the application level and the user's needs one. This rapid evolution of the technology imposed a need for the existence of heterogeneous environments where the coverage is ensured throughout the different available networks. The challenge with such architecture would be to provide the user with the ability to navigate through the different available networks in a transparent and seamless fashion. However, the navigation among different types of networks is commonly referred to as vertical Handover. The IEEE 802.21 stan…