Search results for "bitter"
showing 10 items of 45 documents
Le goût amer : un obstacle à vaincre ?
2010
Potentials for critical raw materials recovery from Mediterranean saltworks bitterns
2022
Minerals extraction from seawater brines is currently regarded as the most practical approach to reduce European dependency from the import of many Critical Raw Materials. The technical feasibility of such approach has been widely demonstrated in several different research and development projects but the economic sustainability has always been found to depend on the local demand for sodium chloride, which is always the most abundant product of the extraction. Starting from this crucial node, the SEArcularMINE project has investigated the possibility to use the residual brines originated by sea-salt extraction in traditional saltworks, regarded as an already well-established marketplace. Th…
Salivary protein profiles are linked to bitter taste acceptance in infants
2014
Salivary protein profiles are linked to bitter taste acceptance in infants. Séminaire final du projet européen HabEat
Taste receptors, innate immunity and longevity: the case of TAS2R16 gene
2019
Abstract Background Innate immunity utilizes components of sensory signal transduction such as bitter and sweet taste receptors. In fact, empirical evidence has shown bitter and sweet taste receptors to be an integral component of antimicrobial immune response in upper respiratory tract infections. Since an efficient immune response plays a key role in the attainment of longevity, it is not surprising that the rs978739 polymorphism of the bitter taste receptor TAS2R16 gene has been shown to be associated with longevity in a population of 941 individuals ranging in age from 20 to 106 years from Calabria (Italy). There are many possible candidate genes for human longevity, however of the many…
Récepteur du goût sucré et diabète
2017
Récepteur du goût sucré et diabète. 6. journée de l'innovation en diabétologie
Functional Gustatory Role of Chemoreceptors in Drosophila Wings
2016
Summary: Neuroanatomical evidence argues for the presence of taste sensilla in Drosophila wings; however, the taste physiology of insect wings remains hypothetical, and a comprehensive link to mechanical functions, such as flight, wing flapping, and grooming, is lacking. Our data show that the sensilla of the Drosophila anterior wing margin respond to both sweet and bitter molecules through an increase in cytosolic Ca2+ levels. Conversely, genetically modified flies presenting a wing-specific reduction in chemosensory cells show severe defects in both wing taste signaling and the exploratory guidance associated with chemodetection. In Drosophila, the chemodetection machinery includes mechan…
The bitter taste of vitamins is mediated by human TAS2R activation
2021
Vitamins play an important role in maintaining normal physiologic and metabolic functions. Vitamins are known to generate bitterness, which may contribute to the off-taste of nutritional supplements. This negative sensation may decrease product acceptability and patient compliance. Few studies have examined taste thresholds and sensory sensing mechanisms at the origin of vitamin taste detection. To better understand vitamin bitterness perception, we combined human sensory analysis and taste receptor functional assays. We measured the aqueous taste detection threshold of four B vitamins using sensory difference tests. Challenging the 25 human bitter taste 2 receptors (TAS2Rs), we found that …
Bitter taste genetics and food preference in italian population
2010
Objective: To investigate the possible role of the polymorphic bitter taste gene, TAS2R38, known to be involved in the perception of the bitter synthetic chemical phenylthiocarbamide (PTC), in influencing food preference and body mass index(BMI). Methods: up to now more than 1500 university students (17-25 years old) at Catania, Cosenza, Rome, Palermo, Pisa, Parma, Chieti, Trento University have been enrolled in the study. DNA was extracted from saliva, and genotyped by TaqMan assay for the most frequent polymorphism (PAV/AVI) of TAS2R38 gene. A possible association between genotype and food preference was assessed by administering a detailed questionnaire for food preferences and life styl…
Sucralose and Cardiometabolic Health: Current Understanding from Receptors to Clinical Investigations
2021
International audience; The excess consumption of added sugar is consistently found to be associated with weight gain, and a higher risk of type 2 diabetes mellitus, coronary heart disease, and stroke. In an effort to reduce the risk of cardiometabolic disease, sugar is frequently replaced by low- and null-calorie sweeteners (LCSs). Alarmingly, though, emerging evidence indicates that the consumption of LCSs is associated with an increase in cardiovascular mortality risk that is amplified in those who are overweight or obese. Sucralose, a null-caloric high-intensity sweetener, is the most commonly used LCS worldwide, which is regularly consumed by healthy individuals and patients with metab…
The «tuera» as a bitter fruit of suffering love: between the Cancionero General (1511) and El rayo que no cesa by Miguel Hernández (1936)
2020
El Cancionero General de Hernando del Castillo (Valencia, 1511) presenta una canción de Pedro Fajardo, Adelantado de Murcia, con un encabezado que remite a unas «tueras» (una especie de pequeña calabaza silvestre), como invención o empresa. El sabor de la «tuera» es muy amargo y por ello, en las escasas ocasiones en que aparece el término en literatura, las «tueras» se asocian con la amargura del sufrimiento amoroso (y a veces tal vez con la gravedad y los pesares del embarazo y la crianza). Encontraremos una nueva utilización poética de la «tuera» solamente cuatro siglos después, en uno de los sonetos de Miguel Hernández, «Fuera menos penado», incluido en su libro El rayo que no cesa (1936…