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showing 10 items of 395 documents

Cognitive functioning in orthostatic hypotension due to pure autonomic failure.

2004

Psychophysiological science proposes close interactions between cognitive processes and autonomic responses, yet the consequences of autonomic failure on cognitive functioning have not been documented. This pilot study investigates, for the first time, the cognitive profile of 14 patients with Pure Autonomic Failure (PAF). Each patient was administered a comprehensive battery of neuropsychological tests and neuroimaging investigation. A number of patients (n = 6) presented with cognitive impairment. The two most frequent types of impairment were: deficits of speed and attention, and executive functioning. Impairments of free recall memory, intellectual functioning, nominal and calculation f…

Malemedicine.medical_specialtyAudiologyArousalOrthostatic vital signsHypotension OrthostaticBorderline intellectual functioningCognitionmedicineChronic fatigue syndromeHumansCognitive skillPsychiatryPure autonomic failureAgedAged 80 and overSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaEndocrine and Autonomic Systemsbusiness.industrypure autonomic failure cognition orthostatic hypotension autonomic nervous systemNeuropsychologyCognitionMiddle Agedmedicine.diseaseMagnetic Resonance ImagingAutonomic Nervous System DiseasesFemaleNeurology (clinical)businessTomography X-Ray ComputedClinical autonomic research : official journal of the Clinical Autonomic Research Society
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Defective jejunal brush border membrane sodium/proton exchange in association with lethal familial protracted diarrhoea.

1990

The spectrum of clinical disease associated with specific defects in jejunal brush border membrane sodium/proton exchange is poorly defined and only two patients have been described so far. Jejunal brush border membrane transport studies were performed in a boy who presented with lethal familial protracted diarrhoea in the first few days of life. Using jejunal brush border membrane vesicles prepared from conventional jejunal biopsy specimens, initial sodium uptake under H+ gradient conditions was found to be only 6% of the mean control value. In contrast, sodium stimulated glucose uptake was normal. Our data confirm the importance of a congenital defect in this exchanger as a cause of sever…

Malemedicine.medical_specialtyCell Membrane PermeabilityBrush borderSodiumGlucose uptakechemistry.chemical_elementBiological Transport ActiveJejunumInternal medicinemedicineHumansProtracted diarrhoeaJejunal biopsyMicrovilliVesicleSodiumGastroenterologyInfant NewbornInfantIon ExchangeDiarrheamedicine.anatomical_structureEndocrinologyJejunumchemistryBiochemistryDiarrhea Infantilemedicine.symptomProtonsResearch ArticleGut
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Electroencephalographic Abnormalities in Autism Spectrum Disorder: Characteristics and Therapeutic Implications.

2020

A large body of literature reports the higher prevalence of epilepsy in subjects with Autism Spectrum Disorder (ASD) compared to the general population. Similarly, several studies report an increased rate of Subclinical Electroencephalographic Abnormalities (SEAs) in seizure-free patients with ASD rather than healthy controls, although with varying percentages. SEAs include both several epileptiform discharges and different non-epileptiform electroencephalographic abnormalities. They are more frequently associated with lower intellectual functioning, more serious dysfunctional behaviors, and they are often sign of severer forms of autism. However, SEAs clinical implications remain controver…

Malemedicine.medical_specialtyMedicine (General)Autism Spectrum Disorderautism spectrum disordersPopulationEpiphenomenonDysfunctional familyChild Behavior DisordersReviewAudiologybehavioral disciplines and activities03 medical and health sciencesEpilepsy0302 clinical medicineBorderline intellectual functioningR5-920mental disordersmedicineHumansCognitive DysfunctioneducationChildSubclinical infectioneducation.field_of_studyEpilepsyEvidence-Based MedicineEpileptogenic abnormalitiebusiness.industryepileptogenic abnormalitiesElectroencephalographyGeneral Medicineelectroencephalogrammedicine.diseaseSettore MED/39 - Neuropsichiatria Infantile030227 psychiatryAutism spectrum disorderAutismAnticonvulsantsFemaleAutism spectrum disorders Electroencephalogram Epilepsy Epileptogenic abnormalities Non-epileptiform abnormalitiesbusinessnon-epileptiform abnormalities030217 neurology & neurosurgeryMedicina (Kaunas, Lithuania)
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The test accuracy of the Montreal Cognitive Assessment (MoCA) by stroke lateralisation

2017

Abstract Background The Montreal Cognitive Assessment (MoCA) is an increasingly popular screening tool for detecting cognitive impairment post-stroke. However its' test accuracy by stroke lateralisation is as yet unknown. Aim Our aim was to investigate whether the test accuracy of the MoCA differs by stroke lateralisation across different cognitive domains. Methods We retrospectively examined the cognitive profiles of 228 subacute stroke patients (86 Left, 142 Right), comparing MoCA-total and domain-specific scores with performance on detailed neuropsychological assessment. Results The prevalence of cognitive impairment detected on neuropsychological assessment was high and relatively compa…

Malemedicine.medical_specialtyNeuropsychological TestsAudiologySensitivity and SpecificityFunctional LateralityLateralization of brain functionExecutive Function03 medical and health sciencesCognition0302 clinical medicineBorderline intellectual functioningPrevalencemedicineHumansCognitive Dysfunction030212 general & internal medicineNeuropsychological assessmentPsychiatryStrokeAgedRetrospective Studiesmedicine.diagnostic_testNeuropsychologyMontreal Cognitive AssessmentCognitionMiddle Agedmedicine.diseaseExecutive functionsStrokeNeurologyFemaleNeurology (clinical)Psychology030217 neurology & neurosurgeryJournal of the Neurological Sciences
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Robotic-assisted pancreaticoduodenectomy with vascular resection. Description of the surgical technique and analysis of early outcomes

2019

Abstract Background Despite the potential benefits, the adoption of the minimally invasive surgery for the treatment of borderline resectable pancreatic cancer is still in the initial phase. We investigated the safety and feasibility of the robotic pancreaticoduodenectomy with venous resection/reconstruction (RPD SMV/PV). Methods Since March 2013 to October 2019, a total of 73 RPD and 10 RPD SMV/PV were performed. The two groups were case-matched according to the preoperative characteristics. Results Mean operative times and estimated blood loss were less in the RPD group in comparison to that in the RPD with SMV-PV group (525 vs 642 min, p = 0.003 and 290 vs 620 ml, p = 0.002, respectively…

Malemedicine.medical_specialtyRobotic assistedmedicine.medical_treatmentOperative TimeAdenocarcinoma030230 surgeryPancreaticoduodenectomy03 medical and health sciences0302 clinical medicineRobotic Surgical ProceduresBorderline resectablePancreatic cancerVascular reconstructionHumansMedicineRobotic surgeryVascular resectionAgedbusiness.industryMortality rateSurgical outcomesRobotic surgeryMiddle Agedmedicine.diseasePancreaticoduodenectomySurgeryPancreatic NeoplasmsTreatment OutcomeOncology030220 oncology & carcinogenesisInitial phaseFemaleSurgerybusinessVascular Surgical Procedures
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Insights into international branch campuses: Mapping trends through a systematic review

2019

Abstract This study analyzes international branch campus (IBC) literature trends from 1960 to 2017 through a systematic review of the different research approaches, views, and positions to map the global scientific production. Over the last two decades, universities worldwide have opened branch campuses abroad, reaching a peak of 249 across thirty-three countries in January 2017. In fact, international studies and surveys have identified a 26% increase over the last five years as well as a concentration of the industry. Since 2017, the emergent field of IBC has experienced a geometric growth regarding the number of academic publications on this topic. The results of the review indicate an i…

MarketingHigher educationInternational studiesbusiness.industry05 social sciencesScientific productionCross-border educationEducació InvestigacióInternationalizationPolitical science0502 economics and businessRegional science050211 marketingbusiness050203 business & managementJournal of Business Research
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Intensità degli scambi agroalimentari tra i Paesi del bacino del Mediterraneo

2013

The Mediterranean has always been an area of strategic interest for the European Union (eu), which, since its establishment, has woven a compact network of relationships with its trading partners in the South and East of the Mediterranean, signing cooperation and then associative agreements with them. This study aims to present a view of how the agro-food trade network has evolved between the eu’s Mediterranean partner countries and their neighbors in North Africa and the Near East. To measure the extent of this trade specific indicators are used which are also widely used in economic literature, albeit to analyze trade in sectors unconnected to agro-food. In particular, analyses carried ou…

Mediterranean climateEconomics and EconometricsMiddle Eastbusiness.industryInternational tradeAgricultural and Biological Sciences (miscellaneous)Trade networkAgro-food productBilateral tradeEuro-Med Policy.GeographyInternational free trade agreementTrade IntensityFood productsSettore AGR/01 - Economia Ed Estimo RuraleBorder trademedia_common.cataloged_instanceEuropean unionbusinessAgronomy and Crop ScienceMediterranean countriemedia_common
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Digital materialities in the diasporic mourning of migrant death

2019

This article examines memorialization among the family and friends of those who have died at the world’s deadliest border in the Mediterranean Sea. Digital media platforms are central spaces for new, innovative forms of coping with ambiguous loss or the inability to mourn over a dead body. The analysis focuses on the role of digital media technologies and the relationship between digital and material elements in memorialization. I examine the creation and circulation of digital objects of memorialization: visual assemblages in which the material and digital intertwine. The analysis demonstrates that digital media practices are not separate from the material world, nor do they make mourning …

MemorializationsurutyöHistoryRefugee0507 social and economic geographysosiaalinen mediabordersdiasporamigrationLanguage and LinguisticsDigital mediapakolaisuusmemoryMediterranean seadeathdigitaalinen kulttuurimaahanmuutto050602 political science & public administrationmuistaminendigital mediaMateriality (auditing)business.industryCommunication05 social scienceskuolema0506 political scienceEthnologybusiness050703 geographymateriality
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The Independent Biological Activity of Bacillus thuringiensis Cry23Aa Protein Against Cylas puncticollis

2020

The Cry23Aa/Cry37Aa proteins from Bacillus thuringiensis (Bt) have been described toxic to Cylas puncticollis larvae. In general, it is believed that Cry23Aa and Cry37Aa act jointly to exert the insecticidal activity, while there is no evidence of their toxicity individually. Therefore, in the present study, the contribution of each protein in the insecticidal activity toward C. puncticollis larvae has been assessed. The results showed that both proteins were toxic for C. puncticollis larvae when tested individually. Contrary to what was claimed previously, our results suggest that the presence of both proteins is not necessary to exert toxicity against C. puncticollis larvae. Also, the bin…

Microbiology (medical)Agriculture and Food SciencesSWEET-POTATO WEEVILlcsh:QR1-502sweet potato weevilsbinary toxinMicrobiologylcsh:Microbiology03 medical and health sciencesmode of actioninsecticidal proteinsBacillus thuringiensisBioassayCry37AaBinding siteSPHAERICUS TOXINMode of action030304 developmental biologybinding assay0303 health sciencesPore-forming toxinLarvabiology030306 microbiologyCRYSTAL PROTEINCOMPONENTSfungiMidgutBiological activityBORDER MEMBRANE-VESICLESENTOMOPATHOGENIC FUNGIbiology.organism_classificationEFFICACYBiochemistrybioassayCOLEOPTERABRUNNEUSRESISTANCEFrontiers in Microbiology
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Mutations in the Bacillus thuringiensis Cry1Ca toxin demonstrate the role of domains II and III in specificity towards Spodoptera exigua larvae

2004

Several mutants of the Bacillus thuringiensis Cry1Ca toxin affected with regard to specific activity towards Spodoptera exigua were studied. Alanine was used to replace single residues in loops 2 and 3 of domain II (mutant pPB19) and to replace residues 541– 544 in domain III (mutant pPB20). Additionally, a Cry1Ca mutant combining all mutations was constructed (mutant pPB21). Toxicity assays showed a marked decrease in toxicity against S. exigua for all mutants, while they retained their activity against Manduca sexta, confirming the importance of these residues in determining insect specificity. Parameters for binding to the specific receptors in BBMV (brush border membrane vesicles) of S.…

Models MolecularMutantLaboratory of Virologyaminopeptidase nmedicine.disease_causeBiochemistrybrush-border membraneToxin oligomerizationSubstrate SpecificityBacterial toxin; Manduca sexta; Mode of action; Protoxin activation; Toxin oligomerization; Toxin receptor bindingHemolysin Proteinsmanduca-sextaBacillus thuringiensisheliothis-virescensAlanine:CIENCIAS DE LA VIDA::Bioquímica [UNESCO]MicrovillibiologyPRI BioscienceBiochemistryMode of actionLarvaThermodynamicsResearch ArticleProtein BindingBacterial Toxinspink-bollwormBacillus thuringiensisSpodopteraSpodopteraBinding CompetitiveManduca sextaLaboratorium voor VirologieBacterial ProteinsExiguamedicineirreversible bindingAnimalscrystal proteinsProtoxin activationProtein Structure QuaternaryMode of actionMolecular BiologyBacillus thuringiensis ToxinsToxin receptor bindingToxininsecticidal toxinpore formationCytoplasmic VesiclesfungiUNESCO::CIENCIAS DE LA VIDA::BioquímicaBacterial toxinCell Biologybiology.organism_classificationProtein Structure TertiaryEndotoxinsManduca sextaMutationcryia delta-endotoxins
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