Search results for "bp"
showing 10 items of 672 documents
IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia
2021
Simple Summary Although the prognosis of acute lymphoblastic leukemia (ALL) has improved significantly during the past decades, ALL remains a major cause of pediatric cancer mortality, and more accurate risk-stratification is required. We investigated IGF2BP3, which has previously been associated with aggressive cancers, and found high and subtype-specific expression of IGF2BP3 in B-cell ALL, that was associated with good outcome in high-risk patients. Results suggest that IGF2BP3 could be useful to improve stratification and prognosis of B-ALL. Abstract The oncofetal protein insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) belongs to a family of RNA-binding proteins involved i…
Liiketoimintaprosessien hallinta - hyödyt ja haasteet
2009
Kemppainen, Virpi Liiketoimintaprosessien hallinta (BPM) hyödyt ja haasteet / Virpi Kemppainen Jyväskylä, Jyväskylän yliopisto, 2009, 28 s. Kandidaatintutkielma Tämän tutkielman tarkoituksena on luoda kokonaiskuva liiketoimintaprosessin hallinnasta (BPM). Liiketoimintaprosessien hallinnalla tarkoitetaan mallia, jossa liiketoiminnan hyötyjä pyritään kasvattamaan tutkimalla ja analysoimalla prosesseja iteroinnin kautta, kunnes saavutetaan haluttu lopputulos. BPM:n käytön keskeisenä tarkoituksena on taata organisaation eri sidosryhmien osallistuminen liiketoiminnan parantamiseen sekä yhteisen kielen löytäminen näiden sidosryhmien välille. Tämä tutkielma on tyyliltään kuvaileva kirjallisuustut…
Mantojuma masas reālā sadalīšana
2020
Temats “Mantojuma masas reālā sadale” ir aktuāls šodien un būs aktuāls vienmēr. Svarīgs aspekts ir tas, ka ar mantojuma masas dalīšanu visbiežāk saskaras nevis viena persona, bet vairākas personas. Tas nozīmē, ka process tiks atrisināts vai nu labprātīgi, vai tiesas ceļā. Darba mērķis ir izpētīt, kā mantojuma masas reālā sadale notiek likumā noteiktajā kārtībā, kad un kuri līdzmantinieki ir tiesīgi prasīt mantojuma sadali un to savstarpējās attiecības, kā arī dalāmas mantas noteikšanu. Lai radītu uzskatāmāku priekšstatu par mantojuma masas reālo sadali, autore apskatīs arī atsevišķu jautājumu regulējumu ārvalstīs. Mērķi tiks sasniegti, apskatot un analizējot citu valstu regulējumus, tiesu p…
Mantojuma tiesību zaudēšana.
2020
Pastāv divi veidi, kā persona labprātīgi var zaudēt sev piemītošo mantojuma tiesību: 1) noslēdzot mantotāja atteikšanās līgumu; 2) atraidot sev piekritušo mantojumu. Svarīgi nodalīt šos divus veidus, jo tie ir pavisam atšķirīgi, tomēr bieži vien tiek jaukti. Mantinieks var gan atraidīt, gan pieņemt sev piekritušo mantojumu klusējot. Līdz ar to, likumā neietverot konkrētu darbību uzskaitījumu, kas liecinātu par mantojuma pieņemšanu klusējot, likumdevējs ar vārdiem ‘’klusējot pieņemts vai atraidīts mantojums’’ ir radījis ģenerālklauzulu, ļaujot katru gadījumu izskatīt atsevišķi. Personas bieži vien uzskata, ka mantojuma aicinājuma ignorēšana automātiski atraida mantojumu, tomēr visos gadījumo…
Diagnostic and prognostic value of H-FABP in acute coronary syndrome: Still evidence to bring
2018
Abstract The assessment of chest pain patients presenting to the emergency area (EA) is still a clinical challenge, as the majority of patients are not diagnosed with acute coronary syndrome (ACS). New generation high sensitivity c-Tn (hs-cTn) assays have showed better performances compared to the standard c-Tn. However, hs-Tn still presents some limitations. Hence, novel, early biomarkers are needed in this setting. Among all, heart-type fatty acid binding protein (H-FABP) has been largely investigated. This article reviews the studies evaluating H-FABP performance in diagnosing acute myocardial infarction (AMI) and stratifying chest pain patients by risk. H-FABP optimal performances in AC…
Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension.
2009
Hypertension in children and adolescents has been gaining ground in cardiovascular medicine, mainly due to the advances made in several areas of pathophysiological and clinical research. These guidelines arose from the consensus reached by specialists in the detection and control of hypertension in children and adolescents. Furthermore, these guidelines are a compendium of scientific data and the extensive clinical experience it contains represents the most complete information that doctors, nurses and families should take into account when making decisions. These guidelines, which stress the importance of hypertension in children and adolescents, and its contribution to the current epidemi…
Twenty-four-hour blood pressure profile in idiopathic REM sleep behavior disorder
2022
Abstract Study Objectives To determine whether autonomic dysfunction in idiopathic REM sleep behavior disorder (iRBD) affects circadian blood pressure (BP) profile. Methods Twenty-one iRBD (mean age 68.8 ± 6.4, mean age at onset 62.2 ± 9.3), 21 drug-free de novo Parkinson’s disease (PD) and 21 control participants (HCs), comparable for age and sex, underwent 24-h ambulatory BP monitoring. A prospective follow-up study was performed to evaluate the occurrence of neurodegenerative disorders in the iRBD cohort. Results In the iRBD group, nighttime systolic BP (SBP) was higher (124.0 ± 20.0, p = .026), nocturnal BP decrease lower (4.0 ± 8.7% for SBP and 8.7 ± 8.0% for diastolic BP [DBP], p = .0…
Malignant paroxysmal positional vertigo
2011
Objective: An insidious percentage of paroxysmal positional vertigo appears to be intractable with canalith repositioning maneuver and also is not self-limiting. This type of positional vertigo is sustained by the action of intracranial tumors that mimics the clinical aspects of benign paroxysmal positional vertigo.Aim of this study is to clarify the features of these forms of positional vertigo, which we indicate as malignant paroxysmal positional vertigo. Methods: We retrospectively reviewed the clinical records of all the patients who presented with vertigo spells and were managed at our tertiary care referral centre over a three years period. Two hundred and eleven patients with diagnos…
Understanding benign paroxysmal positional vertigo: the management of lateral canal involvement
2013
Benign paroxysmal positional vertigo (BPPV) represents the most common cause of peripheral vertigo. The treatment of this apparently intractable disease is actually a physical treatment: performing manoeuvres on the patient to restore the normal condition of the inner ear. However, the following information will help readers who are unfamiliar with BPPV to improve their knowledge of the condition.
The prevalence and predictors of bipolar and borderline personality disorders comorbidity: Systematic review and meta-analysis
2016
Introduction Data about the prevalence of borderline personality (BPD) and bipolar (BD) disorders comorbidity are scarce and the boundaries remain controversial. We conducted a systematic review and meta-analysis investigating the prevalence of BPD in BD and BD in people with BPD. Methods Two independent authors searched MEDLINE, Embase, PsycINFO and the Cochrane Library from inception till November 4, 2015. Articles reporting the prevalence of BPD and BD were included. A random effects meta-analysis and meta-regression were conducted. Results Overall, 42 papers were included: 28 considering BPD in BD and 14 considering BD in BPD. The trim and fill adjusted analysis demonstrated the prevale…