Search results for "capture"
showing 10 items of 463 documents
Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy
2007
Reducing body myopathy (RBM) is a rare disorder causing progressive muscular weakness characterized by aggresome-like inclusions in the myofibrils. Identification of genes responsible for RBM by traditional genetic approaches has been impossible due to the frequently sporadic occurrence in affected patients and small family sizes. As an alternative approach to gene identification, we used laser microdissection of intracytoplasmic inclusions identified in patient muscle biopsies, followed by nanoflow liquid chromatography-tandem mass spectrometry and proteomic analysis. The most prominent component of the inclusions was the Xq26.3-encoded four and a half LIM domain 1 (FHL1) protein, expresse…
Dose determination using alanine detectors in a mixed neutron and gamma field for boron neutron capture therapy of liver malignancies
2011
IntroductionBoron Neutron Capture Therapy for liver malignancies is being investigated at the University of Mainz. One important aim is the set-up of a reliable dosimetry system. Alanine dosimeters have previously been applied for dosimetry of mixed radiation fields in antiproton therapy, and may be suitable for measurements in mixed neutron and gamma fields.Materials and MethodsTwo experiments have been carried out in the thermal column of the TRIGA Mark II reactor at the University of Mainz. Alanine dosimeters have been irradiated in a phantom and in liver tissue.ResultsFor the interpretation and prediction of the dose for each pellet, beside the results of the measurements, calculations …
Technological advancements in the analysis of human motion and posture management through digital devices
2021
Technological development of motion and posture analyses is rapidly progressing, especially in rehabilitation settings and sport biomechanics. Consequently, clear discrimination among different measurement systems is required to diversify their use as needed. This review aims to resume the currently used motion and posture analysis systems, clarify and suggest the appropriate approaches suitable for specific cases or contexts. The currently gold standard systems of motion analysis, widely used in clinical settings, present several limitations related to marker placement or long procedure time. Fully automated and markerless systems are overcoming these drawbacks for conducting biomechanical…
Video feedback in higher education - a contribution to improving the quality of written feedback
2012
Author's version of an article in the journal: Nordic Journal of Digital Literacy. Also available from the publisher at: http://www.idunn.no/ts/dk/2012/02/video_feedback_in_higher_education_-_a_contribution_to_impr The purpose of this article is to promote the significance of feedback regarding students’ working with written texts in higher education and to point out how technology can develop the quality and form of teachers’ feedback. The results of studies and tests completed in eight separate subject areas demonstrate that video feedback simplifies and increases the efficiency of responding to students’ work, as it allows the opportunity to achieve increased levels of precision and qual…
The influence of rhythmic and spectro-timbral musical features on gait-related movement
2017
Music makes us move, and humans have the universal tendency to synchronise their movements to music. This phenomenon has been used in music therapy to help people with movement disorders regain control over their movements. Rhythmic auditory stimulation has shown promising results in gait rehabilitation in various clinical populations. In healthy populations, various differences have been found between movement while walking to musical and metronome stimuli in terms of stride length. However, insufficient research has been conducted concerning the musical features that could evoke this difference, and which gait-related movements might change under the influence of music. The aim of this mo…
Predictive error detection in pianists: A combined ERP and motion capture study
2013
Performing a piece of music involves the interplay of several cognitive and motor processes and requires extensive training to achieve a high skill level. However, even professional musicians commit errors occasionally. Previous event-related potential (ERP) studies have investigated the neurophysiological correlates of pitch errors during piano performance, and reported pre-error negativity already occurring approximately 70–100 ms before the error had been committed and audible. It was assumed that this pre-error negativity reflects predictive control processes that compare predicted consequences with actual consequences of one's own actions. However, in previous investigations, correct a…
GEANT4 simulation of the neutron background of the C6D6 set-up for capture studies at n_TOF
2014
The neutron sensitivity of the C6D6 detector setup used at n_TOF facility for capture measurements has been studied by means of detailed GEANT4 simulations. A realistic software replica of the entire n_TOF experimental hall, including the neutron beam line, sample, detector supports and the walls of the experimental area has beeni mplemented in the simulations. The simulations have been analyzed in the same manner as experimental data, in particular by applying the Pulse Height Weighting Technique. The simulations have been validated against a measurement of the neutron background performed with anatC sample, showing an excellent agreement above 1 keV. At lower energies, an additional compo…
Boron determination in liver tissue by combining quantitative neutron capture radiography (QNCR) and histological analysis for BNCT treatment plannin…
2011
The typical primary malignancies of the liver are hepatocellular carcinoma and cholangiocarcinoma, whereas colorectal liver metastases are the most frequently occurring secondary tumors. In many cases, only palliative treatment is possible. Boron neutron capture therapy (BNCT) represents a technique that potentially destroys tumor tissue selectively by use of externally induced, locally confined secondary particle irradiation. In 2001 and 2003, BNCT was applied to two patients with colorectal liver metastases in Pavia, Italy. To scrutinize the rationale of BNCT, a clinical pilot study on patients with colorectal liver metastases was carried out at the University of Mainz. The distribution o…
Shell-Model Effective Operators for Muon Capture in ^{20}Ne
1999
It has been proposed that the discrepancy between the partially-conserved axial-current prediction and the nuclear shell-model calculations of the ratio $C_P/C_A$ in the muon-capture reactions can be solved in the case of ^{28}Si by introducing effective transition operators. Recently there has been experimental interest in measuring the needed angular correlations also in ^{20}Ne. Inspired by this, we have performed a shell-model analysis employing effective transition operators in the shell-model formalism for the transition $^{20}Ne(0^+_{g.s.})+\mu^- \to ^{20}F(1^+; 1.057 MeV) + \nu_\mu$. Comparison of the calculated capture rates with existing data supports the use of effective transiti…
Resonant enhancement of an oscillating electric field in an atom
2018
When an atom is placed into an oscillating electric field with frequency far from atomic resonances, the atomic electrons partly shield this field at the nucleus. It is conjectured that when the frequency of electric field reaches an atomic resonance, the electric field at the nucleus may be significantly enhanced. In this paper, we systematically study the mechanisms of this enhancement and show that it may reach five orders in magnitude in particular cases. As an application, we consider laser-assisted neutron capture in 139-Lanthanum nucleus and screening and resonance enhancement of nuclear electromagnetic transitions by electrons.