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showing 10 items of 1185 documents

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

2018

Background: DNA methylation at the GFI1-locus has been repeatedly associated with exposure to smoking from the foetal period onwards. We explored whether DNA methylation may be a mechanism that links exposure to maternal prenatal smoking with offspring's adult cardio-metabolic health.Methods: We meta-analysed the association between DNA methylation at GFI1-locus with maternal prenatal smoking, adult own smoking, and cardio-metabolic phenotypes in 22 population-based studies from Europe, Australia, and USA (n= 18,212). DNA methylation at the GFI1-locus was measured in whole-blood. Multivariable regression models were fitted to examine its association with exposure to prenatal and own adult s…

Genetics and Molecular Biology (all)MaleNetherlands Twin Register (NTR)0301 basic medicineResearch paperGFI1 protein humanGFI1-locusraskausResearch & Experimental Medicinecardio-metabolic phenotypesBiochemistryEpigenesis GeneticGLOBAL Meth QTL Consortium0302 clinical medicinePregnancySmoke030212 general & internal medicinematernal prenatal smokingDNA METHYLATIONmedia_commonRISK2. Zero hungereducation.field_of_studySmokingta3142General MedicineMiddle Agedgenetics [Transcription Factors]3. Good healthDNA-Binding ProteinsPhenotypeMedicine Research & ExperimentalCARDIOVASCULAR-DISEASEepigenetiikkaPopulation SurveillancePrenatal Exposure Delayed EffectsDNA methylation/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleDisease SusceptibilityBIOS ConsortiumMedical GeneticsLife Sciences & BiomedicineAdultmedicine.medical_specialtyOffspringBirth weightPopulationMothersgenetics [DNA-Binding Proteins]ta3111MethylationGeneral Biochemistry Genetics and Molecular BiologyDIET03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingtupakointiGeneral & Internal MedicineInternal medicine/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_medicinemedia_common.cataloged_instanceHumansddc:610adverse effects [Maternal Exposure]EXPOSUREEpigeneticsEuropean unioneducationMedicinsk genetikEPIGENOME-WIDE ASSOCIATIONPregnancyBiochemistry Genetics and Molecular Biology (all)Science & Technologybusiness.industryadverse effects [Smoking]DNA Methylationta3121medicine.diseaseBIRTH-WEIGHT030104 developmental biologyEndocrinologyGenetic Locisydän- ja verisuonitauditCpG IslandsCIGARETTE-SMOKINGCESSATIONEnergy Metabolismmetabolism [Myocardium]businessBody mass indexBiomarkersTranscription FactorsEBioMedicine
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Exploratory spatial data analysis of the distribution of regional per capita GDP in Europe, 1980-1995

2000

The aim of this paper is to study the dynamics of European regional per capita product over time and space. This purpose is achieved by using the recently developed methods of Exploratory Spatial Data Analysis. Using a sample of European regions over the 1980-1995 period, we find strong evidence of global and local spatial autocorrelation in per capita GDP throughout the period. The detection of clusters of high and low per capita products during the period is an indication of the persistence of spatial disparities between European regions. This analysis is finally refined by the investigation of the spatial pattern of regional growth. Key words:exploratory spatial data analysis; distributi…

Geography Planning and Development0211 other engineering and technologiesDistribution (economics)Sample (statistics)02 engineering and technologyjel:C21Environmental Science (miscellaneous)spatial autocorrelationGross domestic productregional inequality0502 economics and businessmedia_common.cataloged_instancegestion[ SHS.ECO ] Humanities and Social Sciences/Economies and financesEconomic geography050207 economicsEuropean unionmanagement economics[SHS.ECO] Humanities and Social Sciences/Economics and FinanceSpatial analysismedia_commonbusiness.industryéconomieeconomic theory05 social sciences021107 urban & regional planningConvergence (economics)economics[SHS.ECO]Humanities and Social Sciences/Economics and FinanceSpatial heterogeneityjel:O52european UnionGeographyCommon spatial patternjel:R12jel:R11businessmanagementjel:O18
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The EU'S Explicit and Implicit Heritage Politics

2014

During the past couple of decades, heritage has become topical in a new way in Europe as the concept has been utilized for political purposes in the EU cultural policy. The EU currently administrates or supports three initiatives – the European Heritage Days, the European Union Prize for Cultural Heritage, and the European Heritage Label – that address the fostering of the transnational European cultural heritage. The article discusses the explicit and implicit heritage politics included in these initiatives. In order to understand the constructive and generative nature of the EU heritage politics, it is approached in the article as a discursive meaning-making process consisting of several …

Geography Planning and DevelopmentPublic administrationCultural heritagePoliticsValuesLawta616Cultural heritage managementmedia_common.cataloged_instanceSociologyIndustrial heritageEuropean unionDemographymedia_commonCultural policyGovernmentalityEuropean Societies
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Mediterranean regionalism from territory to trains: spatial politics and planning of macro-regions and transport networks in Spain

2015

The contested planning of European macro-regions and Trans-European Transport Network (TEN-T) exemplifies the complexities of spatial politics, territorial and relational. What stratagems – discursive and cartographic – may regional actors employ in the process, and what can we learn from them? In context of European Union integration policies, we explore Spanish regional politics – discursive and cartographic – surrounding planning of cross-border regions and a TEN-T “Mediterranean Corridor” (and its alternatives). The contested remapping of macro-regions and transport networks reveals the role of spatial planning in the vertebracio (structuration in Catalan) of European territory in disti…

Geography Planning and DevelopmentTransport networkTerritorialitylanguage.human_languagePoliticsGeographyPolitical Science and International RelationsRegionalism (international relations)languagemedia_common.cataloged_instanceCatalanTrainEconomic geographyEuropean unionSpatial planningmedia_commonSpace and Polity
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Sustainability for Food Consumers: Which Perception?

2019

A sustainable future for the community is one of the objectives established by the European Union Agenda 2030. Furthermore, sustainable consumption has been identified as one of the possible trajectories for sustainable development. It is for this reason that food production, distribution and consumption ways cannot be overlooked for sustainability achievement, as well as the consumer&rsquo

Geography Planning and Developmentlcsh:TJ807-830lcsh:Renewable energy sources010501 environmental sciencesManagement Monitoring Policy and Law01 natural sciencesconsumers0502 economics and businessSettore AGR/01 - Economia Ed Estimo RuraleSustainable consumptionmedia_common.cataloged_instanceconsumptionMarketingEuropean unionlcsh:Environmental sciencesSDGs0105 earth and related environmental sciencesmedia_commonSustainable developmentConsumption (economics)lcsh:GE1-350Renewable Energy Sustainability and the Environmentbusiness.industryCorporate governancelcsh:Environmental effects of industries and plants05 social sciencesconsumersustainabilityNatural resourceSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreelcsh:TD194-195SustainabilityFood processing050211 marketingbusiness
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The influence of geography on the spatial agglomeration of production in the European Union

2012

Abstract We investigate the relative impact of geographic features on the location of production in the European Union. Specifically, we attempt to quantify how much of the spatial pattern of GDP can be attributed to exogenous first-nature elements alone and how much can be derived from endogenous second-nature factors. In order to disentangle both effects empirically, we control for second-nature factors. A method based on the decomposition of the per capita GDP variance is applied to a panel of 1,171 European NUTS 3 regions for 2006. We demonstrate that variable and model misspecifications may bias results unless proper allowance is made for spatial autocorrelation and spatial heterogenei…

GeographyAgglomerationGeography Planning and Development[SHS.ECO]Humanities and Social Sciences/Economics and FinanceGross domestic productSpatial heterogeneityGeographyMulticollinearityEarth and Planetary Sciences (miscellaneous)RepartitionEconometricsCommon spatial patternmedia_common.cataloged_instanceSpatial[ SHS.ECO ] Humanities and Social Sciences/Economies and financesEndogeneityStatistics Probability and UncertaintyEuropean union[SHS.ECO] Humanities and Social Sciences/Economics and FinanceGeneral Economics Econometrics and FinanceSpatial analysisComputingMilieux_MISCELLANEOUSmedia_common
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Il contrasto al lavoro non dichiarato: un'analisi comparativa di policies (Tackling Undeclared Work: A Comparative Analysis of Policies)

2013

La forte presenza del sommerso in molti paesi europei e l'evidenza dei suoi effetti negativi sul loro sviluppo rende rilevante l’analisi di quali siano gli strumenti piu efficaci per scoraggiare l'espansione di questo fenomeno negativo per lo sviluppo e la crescita di un paese. In questo quadro, l’articolo, utilizzando l'approccio delle frontiere stocastiche, esplora quanto possa essere efficace l'attuazione di politiche di contrasto al lavoro nero nel contesto dell’Unione Europea. I nostri risultati confermano sia l'analisi delle determinanti di Schneider et al (2010) sia l'importanza delle politiche di deterrenza e di incentivo per contrastare il lavoro non dichiarato.The strong presence …

GeographyEconomymedia_common.cataloged_instanceContext (language use)European unionHumanitiesmedia_commonSSRN Electronic Journal
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International Successions in Spain: The Impact of a New EU Regulation

2009

ABSTRACTThe arrangement of cross-border successions is a real challenge nowadays for both citizens and authorities due to the multicultural profile of today’s societies together with the current diversity of regulations, both at the substantive and conflicts levels. On 14 October 2009, the European Union adopted a new Proposal for a Regulation on international successions, a comprehensive instrument which will entail the harmonization within the EU of the conflicts regulation of cross-borders inheritances. The text finally adopted will necessarily have to provide an adequate equilibrium of the interests of people living in Europe to be successful. Material justice should not only focus on t…

Geographymedia_common.quotation_subjectMulticulturalismLawImmigrationmedia_common.cataloged_instanceHarmonizationPublic administrationEuropean unionEconomic Justicemedia_commonDiversity (politics)Spanish Yearbook of International Law Online
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A Semantic Web Approach for Geodata Discovery

2013

International audience; Currently, vast amounts of geospatial information are o ffered through OGC's services. However this information has limited formal semantics. The most common method to search for a dataset consists in matching keywords to metadata elements. By adding semantics to available descriptions we could use modern inference and reasoning mechanisms currently available in the SemanticWeb. In this paper we present a novel architecture currently in development in which we use state of the art triplestores as the backend of a CSW service. In our approach, each metadata record is considered an instance of a given class in a domain ontology. Our architecture also adds a spatial dat…

Geospatial analysisComputer scienceFormal semantics (linguistics)SemanticWeb0211 other engineering and technologiesInference02 engineering and technologyOntology (information science)computer.software_genreWorld Wide Web[ INFO.INFO-HC ] Computer Science [cs]/Human-Computer Interaction [cs.HC]Minimum bounding box0202 electrical engineering electronic engineering information engineeringontologies[INFO.INFO-HC]Computer Science [cs]/Human-Computer Interaction [cs.HC]ArchitectureSemantic Webcatalogues021101 geological & geomatics engineeringInformation retrievalMetadataOGC servicesgeodata discovery020201 artificial intelligence & image processing[INFO.INFO-HC] Computer Science [cs]/Human-Computer Interaction [cs.HC]computer
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European Issues, but National Campaigning of German Parties

2021

Germany is a political and economic heavyweight in the European Union and political issues that demand for European solutions rather than national policies, like migration or climate change, gained importance on the German public agenda in recent years. Nonetheless, EP elections regularly have the status of second-order elections when it comes to campaigning efforts as well as voter turnout. In 2019, the election turnout was extraordinarily high, and as this chapter shows, German parties focused on political issues mostly addressing the EU level. Implementing successful Facebook campaigns by initiating user engagement and emphasising issues ‘owned’ by their parties, the Greens and the right…

GermanPoliticsUser engagementPolitical sciencePolitical economylanguageVoter turnoutmedia_common.cataloged_instanceTurnoutEuropean unionlanguage.human_languagemedia_common
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