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showing 10 items of 30638 documents

An integrated proteomic and metabolomic study to evaluate the effect of nucleus-cytoplasm interaction in a diploid citrus cybrid between sweet orange…

2018

Key message: Our results provide a comprehensive overview how the alloplasmic condition might lead to a significant improvement in citrus plant breeding, developing varieties more adaptable to a wide range of conditions. Abstract: Citrus cybrids resulting from somatic hybridization hold great potential in plant improvement. They represent effective products resulting from the transfer of organelle-encoded traits into cultivated varieties. In these cases, the plant coordinated array of physiological, biochemical, and molecular functions remains the result of integration among different signals, which derive from the compartmentalized genomes of nucleus, plastids and mitochondria. To dissect …

0106 biological sciences0301 basic medicineProteomicsCitrusCytoplasmCitruProtoplast fusionCybridPlant ScienceProteomicsDisaccharides01 natural sciencesGenomeMass SpectrometryDisaccharideCitrus spp.Electrophoresis Gel Two-DimensionalCell NucleuChromatography High Pressure LiquidCitrus sinensiPlant ProteinsGeneticsChromatography Reverse-Phasefood and beveragesPlant ProteinGeneral MedicineVolatile organic compoundGlucuronateProteomePloidyPlant LeaveCitrus sinensisBreeding programMetabolomicGlucuronatesStomatal conductanceBiology03 medical and health sciencesMetabolomicsGeneticGeneticsMetabolomicsPlant breedingPlastidCitrus sppCell NucleusVolatile Organic CompoundsfungiProteomicDiploidyPlant LeavesPlant Breeding030104 developmental biologyAgronomy and Crop Science010606 plant biology & botanyPlant molecular biology
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Molecular signatures of silencing suppression degeneracy from a complex RNA virus

2021

As genomic architectures become more complex, they begin to accumulate degenerate and redundant elements. However, analyses of the molecular mechanisms underlying these genetic architecture features remain scarce, especially in compact but sufficiently complex genomes. In the present study, we followed a proteomic approach together with a computational network analysis to reveal molecular signatures of protein function degeneracy from a plant virus (as virus-host protein-protein interactions). We employed affinity purification coupled to mass spectrometry to detect several host factors interacting with two proteins of Citrus tristeza virus (p20 and p25) that are known to function as RNA sil…

0106 biological sciences0301 basic medicineProteomicsCitrusInteraction NetworksPathogenesisPlant Sciencemedicine.disease_causePathology and Laboratory Medicine01 natural sciencesInteractomeBiochemistryBimolecular fluorescence complementationRNA interferenceRNA silencing supressorsCitrus tristeza virusMedicine and Health SciencesDegeneracy (biology)Protein Interaction MapsBiology (General)H20 Plant diseasesPlant ProteinsEcologybiologyPlant virusesEukaryotaArgonautePlantsSmall interfering RNANucleic acidsRNA silencingComputational Theory and MathematicsGenetic interferenceExperimental Organism SystemsModeling and SimulationProteomeArgonaute ProteinsHost-Pathogen InteractionsRNA ViralEpigeneticsResearch ArticleClosterovirusRNA virusViral proteinQH301-705.5Arabidopsis ThalianaPlant PathogensComputational biologyGenome ViralBrassicaResearch and Analysis MethodsModels BiologicalPlant Viral Pathogens03 medical and health sciencesCellular and Molecular NeuroscienceViral ProteinsModel OrganismsPlant and Algal ModelsTobaccomedicineGeneticsGenomesNon-coding RNAProtein InteractionsMolecular signaturesMolecular BiologyEcology Evolution Behavior and SystematicsPlant DiseasesHost Microbial InteractionsBiology and life sciencesMass spectrometryOrganismsComputational BiologyProteinsRNA virusPlant Pathologybiology.organism_classificationGene regulationRepressor Proteins030104 developmental biologyU30 Research methodsAnimal StudiesRNAGene expression010606 plant biology & botanyF30 Plant genetics and breeding
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Inter- and intra-specific genomic divergence in Drosophila montana shows evidence for cold adaptation

2018

This work was supported by the Academy of Finland to AH (projects 132619 and 267244) and to MK (projects 268214 and 272927) and NERC (UK) funding to MGR (grants NE/E015255/1 and NE/J020818/1) and PhD studentship to DJP (NE/I528634/1). The genomes of species that are ecological specialists will likely contain signatures of genomic adaptation to their niche. However, distinguishing genes related to ecological specialism from other sources of selection and more random changes is a challenge. Here we describe the genome of Drosophila montana, which is the most extremely cold-adapted Drosophila species. We use branch tests to identify genes showing accelerated divergence in contrasts between col…

0106 biological sciences0301 basic medicineQH301 BiologyAcclimatizationGenome Insectcomparative genomics01 natural sciencesGenomekylmänkestävyysDrosophilia montanaPhylogenysopeutuminen0303 health scienceseducation.field_of_studybiologygenomiikkaCold TemperatureDrosophilaSynonymous substitutionResearch ArticlemahlakärpäsetNichePopulationGenomics010603 evolutionary biologyIntraspecific competitionQH30103 medical and health sciencesecological adaptationPhylogeneticsDrosophila montanaGeneticsAnimalsDrosophila (subgenus)educationGeneEcology Evolution Behavior and Systematics030304 developmental biologyComparative genomicsta1184DASMolecular Sequence Annotationcold tolerancebiology.organism_classificationDiapauseAcclimatization; Animals; Cold Temperature; Diapause; Drosophila/classification; Drosophila/genetics; Drosophila/physiology; Genome Insect; Molecular Sequence Annotation; Phylogeny030104 developmental biologyEvolutionary biologyta1181Adaptation
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A Major QTL Located in Chromosome 8 of Cucurbita moschata Is Responsible for Resistance to Tomato Leaf Curl New Delhi Virus

2020

[EN] Tomato leaf curl New Delhi virus (ToLCNDV) is a bipartite whitefly transmitted begomovirus, responsible since 2013 of severe damages in cucurbit crops in Southeastern Spain. Zucchini (Cucurbita pepo) is the most affected species, but melon (Cucumis melo) and cucumber (Cucumis sativus) are also highly damaged by the infection. The virus has spread across Mediterranean basin and European countries, and integrated control measures are not being enough to reduce economic losses. The identification of resistance genes is required to develop resistant cultivars. In this assay, we studied the inheritance of the resistance to ToLCNDV previously identified in two Cucurbita moschata accessions. …

0106 biological sciences0301 basic medicineQTLTomato leaf curl New Delhi virusResistanceBOTANICAPlant ScienceBiologylcsh:Plant culture01 natural sciencesSyntenyresistance03 medical and health sciencesCucurbitalcsh:SB1-1110Original ResearchPlantes MalaltiessyntenyZucchinifood and beveragesbiology.organism_classificationzucchiniVirusGENETICA030104 developmental biologyToLCNDVCucurbita moschataHumanities010606 plant biology & botanyFrontiers in Plant Science
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Love at first sniff: a spermatophore-associated pheromone mediates partner attraction in a collembolan species

2017

Mate choice is essential in most animals, as a good choice of mating partner largely determines reproductive success. Much evidence shows that olfactory cues play an important role in mate choice. However, the integration of chemical, visual and acoustic cues, often used when both partners meet, makes it hard to test whether olfaction alone can mediate reproductive decisions. Interestingly, several invertebrates have adopted a mating system where males deposit their sperm (packed in spermatophores) in the environment for females to pick up with no visual contact between the sexes. In this case the male cue is conveyed by the spermatophore only. Earlier studies on a species with indirect spe…

0106 biological sciences0301 basic medicineReproductive successEcologyspringtailsspermatophoreZoologysex pheromoneBiologyMating system010603 evolutionary biology01 natural sciencesAttraction03 medical and health sciences030104 developmental biologyMate choiceSex pheromoneSpermatophoreindirect sperm transferPheromoneAnimal Science and ZoologyMatingEcology Evolution Behavior and Systematicssexual chemical communicationAnimal behaviour
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Sugar exchanges in arbuscular mycorrhiza: RiMST5 and RiMST6, two novel Rhizophagus irregularis monosaccharide transporters, are involved in both suga…

2016

SPE IPM INRA UB CT1; International audience; Arbuscular mycorrhizal (AM) fungi are associated with about 80% of land plants. AM fungi provide inorganic nutrients to plants and in return up to 20% of the plant-fixed CO2 is transferred to the fungal symbionts. Since AM fungi are obligate biotrophs, unraveling how sugars are provided to the fungus partner is a key for understanding the functioning of the symbiosis. In this study, we identified two new monosaccharide transporters from Rhizophagus irregularis (RiMST5 and RiMST6) that we characterized as functional high affinity monosaccharide transporters. RiMST6 was characterized as a glucose specific, high affinity H(+) co-transporter. We prov…

0106 biological sciences0301 basic medicineRhizophagus irregularisLightPhysiology[SDV]Life Sciences [q-bio]Plant Sciencearbuscular mycorrhizal fungus01 natural sciencesrhizophagus irregularisGlomeromycotaSoilGene Expression Regulation PlantMycorrhizaeMedicagoPhylogeny2. Zero hungerMutualism (biology)Fungal proteinReverse Transcriptase Polymerase Chain Reactionglucose specificMonosaccharidesfood and beverageshigh affinity H+ co-transporterhigh affinity transporterArbuscular mycorrhizaBiochemistry[SDE]Environmental SciencesFungusSaccharomyces cerevisiaeBiologyFungal Proteins03 medical and health sciencesSymbiosisStress PhysiologicalBotanyGenetics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyRNA MessengerGlomeromycotaObligateCell MembraneGenetic Complementation TestfungiMST5MST6Membrane Transport Proteins15. Life on landmonosaccharide transporterbiology.organism_classification030104 developmental biologyGlucose010606 plant biology & botany
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Exposure to environmental radionuclides is associated with altered metabolic and immunity pathways in a wild rodent

2019

Wildlife inhabiting environments contaminated by radionuclides face putative detrimental effects of exposure to ionizing radiation, with biomarkers such as an increase in DNA damage and/or oxidative stress commonly associated with radiation exposure. To examine the effects of exposure to radiation on gene expression in wildlife, we conducted a de novo RNA sequencing study of liver and spleen tissues from a rodent, the bank vole Myodes glareolus. Bank voles were collected from the Chernobyl Exclusion Zone (CEZ), where animals were exposed to elevated levels of radionuclides, and from uncontaminated areas near Kyiv, Ukraine. Counter to expectations, we did not observe a strong DNA damage resp…

0106 biological sciences0301 basic medicineRodentDNA Repairmedicine.disease_cause01 natural sciencessäteilybiologiachemistry.chemical_compoundRadiation IonizingMyodes glareolusstable isotopepollutionaineenvaihduntaBeta oxidationradionuclides2. Zero hungerbiologyArvicolinaeFatty AcidsRadiation ExposureRNAseqBank voleMolecular AdaptationLiverimmuunijärjestelmäOriginal ArticleUkraineOxidation-ReductionmetsämyyräDNA damageDNA repair010603 evolutionary biologyMicrobiology03 medical and health sciencesImmunitybiology.animalGeneticsmedicineAnimalsEcology Evolution Behavior and SystematicsRadioisotopesFatty acid metabolismLipid metabolismDNAbiology.organism_classificationLipid MetabolismOxidative Stress030104 developmental biologychemistryChernobyl Nuclear Accident13. Climate actionImmune SystemRNAORIGINAL ARTICLESOxidative stressSpleenDNA DamageMutagens
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Borrelia afzeliialters reproductive success in a rodent host

2018

The impact of a pathogen on the fitness and behaviour of its natural host depends upon the host–parasite relationship in a given set of environmental conditions. Here, we experimentally investigated the effects ofBorrelia afzelii,one of the aetiological agents of Lyme disease in humans, on the fitness of its natural rodent host, the bank vole (Myodes glareolus), in semi-natural conditions with two contrasting host population densities. Our results show thatB. afzeliican modify the reproductive success and spacing behaviour of its rodent host, whereas host survival was not affected. Infection impaired the breeding probability of large bank voles. Reproduction was hastened in infected females…

0106 biological sciences0301 basic medicineRodentmetsämyyräOffspringHost–pathogen interactionZoologyzoonoosithost-pathogen interactionBorrelia afzeliimedicine.disease_cause010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesbiology.animalMyodes glareolusisäntäeläimetnatural hostmedicineMatingGeneral Environmental ScienceEcologyGeneral Immunology and MicrobiologybiologyReproductive successHost (biology)General Medicinezoonosislisääntyminenbiology.organism_classificationfitnessBorrelia-bakteeritBank vole030104 developmental biologyBorrelia afzeliita1181host–pathogen interactionGeneral Agricultural and Biological SciencesProceedings of the Royal Society B: Biological Sciences
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Prebiotic effect of xylooligosaccharides produced from birchwood xylan by a novel fungal GH11 xylanase.

2017

34 p.-4 fig.-1 tab.

0106 biological sciences0301 basic medicineSCFAsBreast-fedStaphylococcus hominisMicroorganismmedicine.medical_treatmentOligosaccharidesXyloseBiologyXylosidase01 natural sciencesAnalytical Chemistry03 medical and health scienceschemistry.chemical_compound010608 biotechnologyXylobiosemedicineGlycoside hydrolaseEndo-14-beta XylanasesPrebioticHydrolysisGeneral MedicineXylanLactic acid030104 developmental biologyPrebioticschemistryBiochemistryTalaromycesXOSXylanaseXylansMicrobiomeBifidobacteriumFood ScienceFood chemistry
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Expression properties exhibit correlated patterns with the fate of duplicated genes, their divergence, and transcriptional plasticity in Saccharomyco…

2017

Gene duplication is an important source of novelties and genome complexity. What genes are preserved as duplicated through long evolutionary times can shape the evolution of innovations. Identifying factors that influence gene duplicability is therefore an important aim in evolutionary biology. Here, we show that in the yeast Saccharomyces cerevisiae the levels of gene expression correlate with gene duplicability, its divergence, and transcriptional plasticity. Genes that were highly expressed before duplication are more likely to be preserved as duplicates for longer evolutionary times and wider phylogenetic ranges than genes that were lowly expressed. Duplicates with higher expression lev…

0106 biological sciences0301 basic medicineSaccharomyces cerevisiae ProteinsGene duplicationDuplicabilityPlant Biology & BotanySaccharomyces cerevisiaeSaccharomyces cerevisiae01 natural sciencesDivergenceEvolution Molecular03 medical and health sciencesGenes DuplicateGene Expression Regulation FungalGene expressionGene duplicationGeneticsSelection GeneticSaccharomycotinaPromoter Regions GeneticMolecular BiologyGenePhylogenybiologyPhylogenetic treeGenetic VariationPromoterGeneral MedicineFull Papersbiology.organism_classification030104 developmental biologyEvolutionary biologyTranscriptional plasticityGene expressionGenome Fungal010606 plant biology & botany
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