Search results for "centri"
showing 10 items of 869 documents
Proteomic analysis of extracellular vesicles secreted by primary human epithelial endometrial cells reveals key proteins related to embryo implantati…
2022
Abstract Background Successful implantation is dependent on coordination between maternal endometrium and embryo, and the role of EVs in the required cross-talk cell-to-cell has been recently established. In this regard, it has been reported that EVs secreted by the maternal endometrium can be internalized by human trophoblastic cells transferring their contents and enhancing their adhesive and invasive capacity. This is the first study to comprehensively evaluate three EV isolation methods on human endometrial epithelial cells in culture and to describe the proteomic content of EVs secreted by pHEECs from fertile women. Methods Ishikawa cells and pHEECs were in vitro cultured and hormonall…
Conversion of Dupin Cyclide Patches into Rational Biquadratic Bézier Form
2005
This paper uses the symmetry properties of circles and Bernstein polynomials to establish a series of interesting barycentric properties of rational biquadratic Bezier patches. A robust algorithm is presented, based on these properties, for the conversion of Dupin cyclide patches into Bezier form. A set of conversion examples illustrates the use of this algorithm.
Evaluation of the Physicochemical Properties of the Iron Nanoparticle Drug Products: Brand and Generic Sodium Ferric Gluconate
2021
Complex iron nanoparticle-based drugs are one of the oldest and most frequently administered classes of nanomedicines. In the US, there are seven FDA-approved iron nanoparticle reference drug products, of which one also has an approved generic drug product (i.e., sodium ferric gluconate (SFG)). These products are indicated for the treatment of iron deficiency anemia and are administered intravenously. On the molecular level, iron nanomedicines are colloids composed of an iron oxide core with a carbohydrate coating. This formulation makes nanomedicines more complex than conventional small molecule drugs. As such, these products are often referred to as nonbiological complex drugs (e.g., by t…
Kinetics of streptolysin O self-assembly.
1995
Streptolysin O is a member of a family of membrane-damaging toxins that bind to cell membranes containing cholesterol and then polymerize to form large pores. We have examined the kinetics of toxin action using 125I-labelled streptolysin O. Binding of toxin monomers to membranes displays first-order kinetics and is reversible; the rate of desorption from red cells shows a marked dependence on temperature. To study oligomerization, toxin was bound to erythrocytes at 0 degrees C. Oligomer formation was then triggered by a sudden temperature shift and stopped by solubilization of membranes with deoxycholate. While at moderately high streptolysin O concentrations oligomerization behaves as a re…
3D digitization of transparent objects by polalization techniques in IR & by triangulation in UV
2011
Two non-conventional methods for the 3D digitization of transparent objects via non-contact measurement are reported in this thesis. 3D digitization is a well acknowledged technique for opaque objects and various commercial solutions based on different measurement approaches are available in the market offering different types of resolution at different prices. Since these techniques require a diffused or lambertian surface, their application to transparent surfaces fails. Indeed, rays reflected by the transparent surface are perturbed by diverse inter-reflections induced by the refractive properties of the object. Therefore, in industrial applications like quality control, the transparent …
Preferential Type II Muscle Fiber Damage From Plyometric Exercise
2012
Context: Plyometric training has been successfully used in different sporting contexts. Studies that investigated the effect of plyometric training on muscle morphology are limited, and results are controversial with regard to which muscle fiber type is mainly affected. Objective: To analyze the skeletal muscle structural and ultrastructural change induced by an acute bout of plyometric exercise to determine which type of muscle fibers is predominantly damaged. Design: Descriptive laboratory study. Setting: Research laboratory. Patients or Other Participants: Eight healthy, untrained individuals (age = 22 ± 1 years, height = 179.2 ± 6.4 cm, weight = 78.9 ± 5.9 kg). Intervention(s): Partici…
Frequency of Left Ventricular Hypertrophy in Non-Valvular Atrial Fibrillation
2015
Left ventricular hypertrophy (LVH) is significantly related to adverse clinical outcomes in patients at high risk of cardiovascular events. In patients with atrial fibrillation (AF), data on LVH, that is, prevalence and determinants, are inconsistent mainly because of different definitions and heterogeneity of study populations. We determined echocardiographic-based LVH prevalence and clinical factors independently associated with its development in a prospective cohort of patients with non-valvular (NV) AF. From the "Atrial Fibrillation Registry for Ankle-brachial Index Prevalence Assessment: Collaborative Italian Study" (ARAPACIS) population, 1,184 patients with NVAF (mean age 72 ± 11 yea…
FAMILIA Y LUCHA A LA POBREZA EN ITALIA: HACIA UN MODELO DESIGUAL Y POLICÉNTRICO EN TIEMPOS DE CRISIS
2018
Il saggio analizza, nella prospettiva dell'ordinamento multilivello, il sistema di reddito minimo garantito vigente in Italia (reddito di inclusione attiva ex d.lgs. 147/2017): la tesi di fondo è che l'attuale sistema di lotta contro la povertà familiare è scarsamente efficace, in ragione degli stretti meccanismi di condizionalità, degli importi di modesta rilevanza, e della distribuzione di competenze Stato-Regioni. El ensayo analiza, desde la perspectiva multinivel, el sistema de renta mínima garantizada vigente en Italia (reddito di inclusione attiva) introducido en 2017: la tesis del autor es que estamos en frente de un modelo muy poco eficaz para luchar contra la pobreza familiar, en r…
Resilience in small urban centers with a strong historical connotation
2015
La resilienza della città storica, misurata dagli eventi rispetto a calamità naturali e fenomeni emergenziali, si presenta spesso al di sopra di qualunque aspettativa. Soprattutto quando principio insediativo, trasformazioni consequenziali a calamità e ridondanze hanno di fatto aumentato la coping capacity e la capacity of response del costruito storico rendendole elevate e di significato. Nonostante ciò la necessità di implementazione di nuove qualità, nell’ottica di riappropriazione dei patrimoni urbani disseminati nel territorio e spesso abbandonati o poco popolati, pone il bisogno di retrofit, manutenzione e misure gestionali che incrementino sicurezza e resilienza. Potendosi indubbiame…
Two New Retigerane-Type Sesterterpenoids from the Lichen Leprocaulon microscopicum
2016
International audience; Two new sesterterpenes, 1 and 2, have been isolated from the lichen Leprocaulon microscopicum. In addition to classic chromatographic methods, a liquid-liquid chromatography technique, namely centrifugal partition chromatography (CPC) was applied for the purification of compound 2. The structures were determined by analyses of mass spectrometry and 1D- and 2D-NMR data. The relative configuration of the isolated compounds was assigned on the basis of 2D-NOESY experiments. The two compounds possess a rare pentacyclic carbon skeleton typical for lichen metabolism, and quite unusual in the vegetal kingdom.