Search results for "chronic"
showing 10 items of 3309 documents
When, why, and how to perform wire-based antegrade dissection and reentry technique
2022
Antegrade dissection and reentry (ADR) refers to an attempt to cross a coronary chronic total occlusion (CTO) lesion through wire and/or equipment passage in the subintimal space followed by reentry to the distal true lumen. From the original subintimal tracking and reentry (STAR) technique description by Colombo in 2005, refinement of the technique, improved characteristics of the microcatheters and wires, and better understanding of subadventitial vessel trauma have led to higher success rates, lower complications rates, and improved long-term outcomes. In this chapter, we discuss the technique, its outcomes, and limitations.
Bacterial and viral infections and related inflammatory responses in chronic obstructive pulmonary disease
2021
Abstract In chronic obstructive pulmonary disease (COPD) patients, bacterial and viral infections play a relevant role in worsening lung function and, therefore, favour disease progression. The inflammatory response to lung infections may become a specific indication of the bacterial and viral infections. We here review data on the bacterial–viral infections and related airways and lung parenchyma inflammation in stable and exacerbated COPD, focussing our attention on the prevalent molecular pathways in these different clinical conditions. The roles of macrophages, autophagy and NETosis are also briefly discussed in the context of lung infections in COPD. Controlling their combined response…
Ricostruire la diacronia della sintassi ladino-dolomitica con l'aiuto di Joppi. Il caso dei costrutti percettivi
2016
L'articolo discute la duplice variazione che riguarda i costrutti percettivi delle varietà ladine: da un lato l'uso di due forme verbali diverse (gerundi e infiniti preposizionali), e dall'altro le differenze tra questi costrutti in ladino e nelle varietà iberoromanze. Sulla base dei dati tratti principalmente dalla raccolta di testi friuliani di Vincenzo Joppi (1878), si mostrerà come le peculiarità dei costrutti percettivi ladini siano dovute al loro carattere conservativo, ma anche a un'innovazione interna al ladino. This article suggests that a diachronic analysis of a specific syntactic phenomenon in Romance allows us to formulate hypotheses that can be extended to those varieties that…
Atrial fibrillation is associated with a marker of endothelial function and oxidative stress in patients with acute myocardial infarction
2016
IF 4.066; International audience
Influenza vaccination in high-risk groups: a revision of existing guidelines and rationale for an evidence-based preventive strategy.
2016
Summary Influenza, an infectious respiratory disease, is one of the main causes of excess winter deaths (EWDs) in Europe. Annual flu epidemics are associated with high morbidity and mortality rates, especially among the elderly, those with underlying health conditions and pregnant women. Health Care Workers (HCWs) are also considered at high risk of both contracting influenza and spreading the virus to vulnerable patients. During the 2014/2015 season, the excess winter mortality rates observed in countries of the northern hemisphere (EuroMOMO network) and in Italy (+13%) were strongly related to the intensity of influenza circulation. Influenza vaccination is the most important public healt…
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia
2013
Genome-wide association studies (GWAS) have previously identified 13 loci associated with risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify additional CLL susceptibility loci, we conducted the largest meta-analysis for CLL thus far, including four GWAS with a total of 3,100 individuals with CLL (cases) and 7,667 controls. In the meta-analysis, we identified ten independent associated SNPs in nine new loci at 10q23.31 (ACTA2 or FAS (ACTA2/FAS), P = 1.22 × 10-14), 18q21.33 (BCL2, P = 7.76 × 10-11), 11p15.5 (C11orf21, P = 2.15 × 10 -10), 4q25 (LEF1, P = 4.24 × 10-10), 2q33.1 (CASP10 or CASP8 (CASP10/CASP8), P = 2.50 × 10-9), 9p21.3 (CDKN2B-AS1, P = 1.27 × 10…
[Recommendations for end-of-life care in patients with chronic obstructive pulmonary disease].
2009
Over the last 20 years, advances in the treatment of patients with chronic obstructive pulmonary disease (COPD) have improved survival even among patients in the most advanced stages of the disease, such as those requiring domiciliary oxygen therapy.1,2 This improvement—in principle a positive development—has given rise to considerable clinical problems associated with the establishment of a therapeutic ceiling and the difficulty of determining prognosis in some of these patients. In this situation, the clinician should consider introducing palliative care, that is, care aimed at improving symptom control, communication, physical activity, and emotional support, in order to achieve the best…
The pros and cons of the implementation of a chronic care model in European rural primary care: the points of view of European rural general practiti…
2021
Introduction: This article describes the views of European rural general practitioners regarding the strengths, weaknesses, opportunities and threats (SWOT) of the implementation of a chronic care model (CCM) in European rural primary care. Methods: This was a mixed-methods online survey. Data were collected from 227 general practitioners between May and December 2017. Categorical data were analysed using descriptive methods while free-text responses were analysed using qualitative methods. The setting was rural primary care in nine European countries (including Central and Eastern Europe). Main outcomes measures were respondents' evaluations of a chronic care model in their rural heal…
Vēsture: Sabiedrība, pārvalde un saimniecība Baltijas jūras reģionā no aizvēstures līdz jaunajiem laikiem
2012
Šajā LU Rakstu sējumā iekļautie raksti pamatojas gan uz referātiem, kas tikuši nolasīti 2008.–2010. gadā LU 66., 67. un 68. zinātniskās konferences Arheoloģijas, kā arī Viduslaiku un jauno laiku vēstures sekcijā, gan uz LU Vēstures un filozofijas fakultātes doktorantu pētījumiem. Raksti ir sadalīti divās daļās, kas, lai gan hronoloģiski pārklājas, tomēr atspoguļo dažādas vēstures jomas – pirmā krājuma daļa ir veltīta aktuāliem arheoloģiskiem pētījumiem, savukārt otrajā daļā iekļautie raksti pievēršas viduslaiku un jauno laiku vēstures problemātikai. Krājuma rakstos no dažādām pētnieciskām perspektīvām aplūkoti Baltijas jūras reģiona – pārsvarā Latvijas teritorijas (viena raksta gadījumā att…
Die chronisch rekurrierende multifokale Osteomyelitis (CRMO)
1998
Chronic recurrent multifocal osteomyelitis (CRMO) is an unusual clinical entity. More than 200 cases are described in the literature and it is presented here with special reference to its radiological aspects. It is an acquired disease of the skeleton which occurs predominantly during childhood and adolescence. About ten per cent of cases begin in early or, rarely, in later adult life. This variant is described here for the first time and is discussed as "adult CRMO". The underlying pathology is a bland, predominantly lympho-plasma cellular osteomyelitis which is self-limiting and leads to bone sclerosis (Garre). It probably involves an abnormal immune process which follows an infection but…