Search results for "complementary and alternative medicine"
showing 10 items of 632 documents
Neoclerodane Diterpenoids from Teucrium massiliense
1998
A reinvestigation of the diterpene metabolites of Teucrium massiliense L. allowed the isolation of four new neoclerodane derivatives, teumassilenins A-D, together with all the diterpenoids previously reported as constituents of this plant. The structures of the new compounds (1-4) were established by chemical and spectroscopic means. A plausible biogenetic relationship between several of these substances is briefly discussed, and some unpublished physical and spectroscopic data of the previously known diterpenoid teumassin (5) are now reported.
X-ray Crystal Structure of Woodinine and Conformational Analysis by Semiempirical and 1H-NMR Methods
1997
The mol. structure of (-)-woodinine (I), a carboline-based alkaloid with antibacterial and antimycobacterial activities, was investigated by X-ray crystallog., NMR, and semiempirical quantum chem. methods. The X-ray crystal structure of I showed the indole ring in the expected planar conformation, the pyrrolidine ring in an envelope conformation, and a weak intramol. hydrogen bond between the pyrrolidine nitrogen and the proton of the indole nitrogen. NMR expts. indicated that this hydrogen bond is not present in soln. and that further differences exist between the crystal and the soln. structures of I. By semiempirical quantum chem. methods, different local energy min. conformations of I, …
Metabolites from the Aerial Parts of the Sicilian Population of Artemisia alba
2013
Phytochemical investigation of the CH2Cl2 extract of the aerial parts of Artemisia alba Turra afforded one new irregular sesquiterpenoid, artemiric acid, and five known metabolites: hydroxydavanone, the coumarins isofraxidin and scopoletin, (6 S*,7 S*,10 R*)–6,10-dimethyl-7,10-epoxyocta-11-enoic acid and artalbic acid. From the MeOH extract three flavonoids were identified: chrysoeriol, quercetin and isorhamnetin. The possible biogenetic pathways of artemiric and artalbic acids are discussed.
Chemical composition of the essential oils of Centaurea sicana and C. giardinae growing wild in Sicily
2008
The essential oils of Centaurea sicana (S) and C. giardinae (G) were studied by GC and GC-MS. Thirty constituents for S, representing 81.5% of the total oil, and 24 compounds for G (94.2% of the total) were identified. The oils were rich in sesquiterpenoids (47.9% for S and 54.7% for G) and hydrocarbons (25.9% for S and 31.7% for G). Germacrene D (13.3%), ( E)-β-farnesene (8.3%), nonacosane (7.3%), heptacosane (6.5%) and phytol (6%) were recognized as the main constituents for S, while caryophyllene oxide (17.7%), nonacosane (14.5%), germacrene D (11.5%), caryophyllene (11.2%) and heptacosane (10.3%) were the main compounds for G.
Visualisierung von meridianähnlichen Ausbreitungspfaden nach optischer Reizung im infraroten Spektralbereich – Vorläufige Ergebnisse
2006
Zusammenfassung Mit Hilfe optischer Anregung durch indirekte Moxibustion im Infrarotbereich von 3,4 bis 5 m (3.400–5.000 nm) gelingt es, mit einer Infrarot-Kamera, die in diesem Bereich arbeitet, “Strukturen” sichtbar zu machen. Der Verlauf solcher Bahnen zeigt Ahnlichkeiten mit den bekannten Meridianen/Leitbahnen der chinesischen Medizin. Die relativ stabile Anregung erfolgt teilweise erst nach wiederholten Versuchen. Variationen der Relativposition der Moxazigarre, mit der die indirekte Moxibustion in einem KOrperabstand von einem bis mehreren Dezimetern durchgefuhrt wird, konnen lokale Verschiebungen dieser “meridianahnlichen Leitbahnen (MAL)” induzieren, deren Bahnen dann nur noch teilw…
A Review of the Phytochemistry, Traditional Uses and Biological Activities of the Essential Oils of Genus Teucrium
2020
AbstractThe genus Teucrium is a large and polymorphic genus of the Lamiaceae family distributed in mild climate zones, particularly in the Mediterranean basin and Central Asia. Studies of nonvolatile constituents of Teucrium species showed that they are a rich source of neo-clerodane diterpenoids, considered as chemotaxonomic markers of the genus. In addition to the nonvolatile metabolites, there has been a large interest in the essential oils of this genus. In this review, a complete survey of the chemical composition and biological properties of the essential oils isolated from Teucrium taxa is provided. In traditional medicine, since ancient times, species of this genus have been widely …
Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants.
2011
BACKGROUND: Natural products are well recognized as sources of drugs in several human ailments. In the present work, we carried out a preliminary screening of six natural compounds, xanthone V(1) (1); 2-acetylfuro-1,4-naphthoquinone (2); physcion (3); bisvismiaquinone (4); vismiaquinone (5); 1,8-dihydroxy-3-geranyloxy-6-methylanthraquinone (6) against MiaPaCa-2 pancreatic and CCRF-CEM leukemia cells and their multidrug-resistant subline, CEM/ADR5000. Compounds 1 and 2 were then tested in several other cancer cells and their possible mode of action were investigated. METHODOLOGY/FINDINGS: The tested compounds were previously isolated from the Cameroonian medicinal plants Vismia laurentii (1,…
Tannins from Hamamelis virginiana Bark Extract: Characterization and Improvement of the Antiviral Efficacy against Influenza A Virus and Human Papill…
2014
Antiviral activity has been demonstrated for different tannin-rich plant extracts. Since tannins of different classes and molecular weights are often found together in plant extracts and may differ in their antiviral activity, we have compared the effect against influenza A virus (IAV) of Hamamelis virginiana L. bark extract, fractions enriched in tannins of different molecular weights and individual tannins of defined structures, including pseudotannins. We demonstrate antiviral activity of the bark extract against different IAV strains, including the recently emerged H7N9, and show for the first time that a tannin-rich extract inhibits human papillomavirus (HPV) type 16 infection. As the …
Protective effect of apocynin in a mouse model of chemically-induced colitis.
2013
Apocynin, a constituent of Picrorhiza kurroa, successfully inhibits NADPH oxidase and shows promise as an anti-inflammatory drug. Now, we report anti-inflammatory effects of apocynin in an experimental colitis model induced by dextran sulfate sodium as well as the effects on the mediators involved in this process. Apocynin reduced the colitis induced in mice by administration of 5 % dextran sulfate sodium during 7 days. Mice were fed a control diet or a diet supplemented with 2 % of apocynin or 2 % of rutin. Sulfasalazine (50 mg/kg, p. o.) was used as a positive control. Treatment with apocynin and rutin ameliorated the course of colonic inflammation with results similar to those of the ref…
Quantification of phenolic acids by partial least squares Fourier-transform infrared (PLS-FTIR) in extracts of medicinal plants.
2020
Introduction Phenolic compounds are ubiquitous compounds found in all plants as their secondary metabolites. Phenols are becoming increasingly important particularly because of their beneficial effects on health. Objective To provide a faithful calibration model for the simultaneous determination and quantification of phenolic acids, as salicylic, vanillic, p-hydroxybenzoic acids, eugenol and thymol in different extracts of medicinal plants, a comparative study was made between two methods of infrared measurements based on attenuated total reflectance (ATR) and transmission. Methods Characteristic absorbance peak heights of mid-infrared spectra of individual phenolic acids were measured for…