Search results for "conte"
showing 10 items of 10369 documents
"No better, no worse - but definitely different" : the presentation of target cultures in two English textbook-series for Finnish secondary school ch…
2007
MTOR inhibitor-based combination therapies for pancreatic cancer
2018
Background: Although the mechanistic target of rapamycin (MTOR) kinase, included in the mTORC1 and mTORC2 signalling hubs, has been demonstrated to be active in a significant fraction of patients with pancreatic ductal adenocarcinoma (PDAC), the value of the kinase as a therapeutic target needs further clarification. Methods: We used Mtor floxed mice to analyse the function of the kinase in context of the pancreas at the genetic level. Using a dual-recombinase system, which is based on the flippase-FRT (Flp-FRT) and Cre-loxP recombination technologies, we generated a novel cellular model, allowing the genetic analysis of MTOR functions in tumour maintenance. Cross-species validation and pha…
High Frequency Data Acquisition System for Modelling the Impact of Visitors on the Thermo-Hygrometric Conditions of Archaeological Sites: A Casa di D…
2018
[EN] The characterization of the microclimatic conditions is fundamental for the preventive conservation of archaeological sites. In this context, the identification of the factors that influence the thermo-hygrometric equilibrium is key to determine the causes of cultural heritage deterioration. In this work, a characterization of the thermo-hygrometric conditions of Casa di Diana (Ostia Antica, Italy) is carried out analyzing the data of temperature and relative humidity recorded by a system of sensors with high monitoring frequency. Sensors are installed in parallel, calibrated and synchronized with a microcontroller. A data set of 793,620 data, arranged in a matrix with 66,135 rows and …
Environmental Effects on Mechanical, Thermophysical and Electrical Properties of Epoxy Resin Filled with Carbon Nanofillers
2019
The aim of this work was to establish the effect of environmental factors (moisture and temperature) on some mechanical, electrical and thermal properties of epoxy-based composites filled with carbon nanofillers: nanotubes (CNT), nanofibers (CNF) and hybrid nanofiller (nanotubes/nanofibers in the ratio 1:1) and to reveal the most environmentally stable NC. First, the nanocomposites (NC) containing different nanofiller contents were prepared to evaluate electrical percolation threshold and to choose NC at certain electrical conductivity for further characterization of the physical properties in initial state and during/after environmental ageing. The environmental ageing consisted of water a…
Análisis de la representación e impacto de los think tanks españoles en la prensa online (2012-2016)
2017
Esta investigación se inscribe en el marco de los estudios nacionales e internacionales en los que se analiza la labor de los «think tanks» como difusores de conocimiento y, al mismo tiempo, como actores sociales que contribuyen a la reforma de las políticas públicas. El estudio se centra en las estrategias comunicativas de los «think tanks» en la prensa online. En la combinación de todas las diferentes estrategias y en una constante adaptación a la situación en la que realizan sus labores estará la clave del éxito para evaluar su influencia y el éxito que tienen en comunicar ideas. Las hipótesis de esta tesis son: H1: Las apariciones de los «think tanks» españoles en los medios online son …
Análisis de la autopercepción en base al modelo tpack en los futuros y las futuras docentes de educación primaria
2020
El avance de las tecnologías digitales está haciendo que los procesos de enseñanza-aprendizaje se vean modificados ante la necesidad de incorporar las TIC en la labor docente. En esta circunstancia, la formación inicial se torna indispensable de cara a una implementación que tenga en cuenta todos los aspectos que interfieren en el proceso educativo. Para ello, modelos que tengan en cuenta las diferentes dimensiones conceptuales, pedagógicas y tecnológicas pueden ayudar en una óptima inserción de la tecnología digital en la escuela. Por ello, esta investigación de carácter descriptivo analiza las autopercepciones en base al modelo TPACK (Technological Pedagogical Content Knowledge) de un tot…
Knowing matters : how students address lack of knowledge in bilingual classroom interaction
2014
(no title)
2017
Biological invasions are recognized as a significant evolutionary factor over short time scales. In particular, their effect is well recorded on the genetic structure of populations, the patterns of phenotypic evolution and the richness of parasite fauna associated to invasive populations. This study aims at quantifying the consequences of a biological invasion according to these three levels (genetical, phenotypical and parasitological) taking as example the Mozambique tilapia Oreochromis mossambicus. This African cichlid is characterized by an unusual conservation status since it is both (i) ranked among the world's worst invasive species due to its global dispersion during the 20th centu…
El retablo de San Estanislao de Kostka en San Luis de los franceses de Sevilla
2020
El templo de San Luis de los franceses de Sevilla, construido a lo largo de las primeras décadas del siglo XVIII, dispone de un complejo programa visual. El retablo de San Estanislao de Kostka ocupa una importante capilla, en paralelo a la de San Francisco de Borja. Como todo retablo, cumple dos funciones: la contemplativa, o conductora de la oración a través de su imagen conceptual, y la formativa por medio del discurso visual desplegado en las calles laterales y el ático. Se afronta el análisis de ambas facetas mediante una aproximación a sus fuentes literarias y emblemáticas.
Single-cell analysis of population context advances RNAi screening at multiple levels
2012
Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironment, in image‐based RNAi screens. We developed a comprehensive computational approach that employs Bayesian and multivariate methods at the single‐cell level. We applied these methods to 45 RNA interference screens of various sizes, including 7 druggable genome and 2 genome‐wide screens, analysing 17 different mammalian virus infections and four related cell physiological processes. Analysing cell‐based screens at this depth reveals widespread RNAi‐induce…