Search results for "corona"

showing 10 items of 3472 documents

Dynamic contrast-enhanced myocardial perfusion imaging using saturation-prepared TrueFISP.

2002

Purpose To develop and test a saturation-recovery TrueFISP (SR-TrueFISP) pulse sequence for first-pass myocardial perfusion imaging. Materials and Methods First-pass magnetic resonance imaging (MRI) of Gd-DTPA (2 mL) kinetics in the heart was performed using an SR-TrueFISP pulse sequence (TR/TE/α = 2.6 msec/1.4 msec/55°) with saturation preparation TD = 30 msec before the TrueFISP readout. Measurements were also performed with a conventional saturation-recovery TurboFLASH (SRTF) pulse sequence for comparison. Results SR-TrueFISP images were of excellent quality and demonstrated contrast agent wash-in more clearly than SRTF images. The signal increase in myocardium was higher in SR-TrueFISP …

AdultGadolinium DTPAMaterials scienceImage qualityContrast MediaImage processingStatistics NonparametricMyocardial perfusion imagingNuclear magnetic resonancePrecontrastCoronary CirculationmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingImage resolutionmedicine.diagnostic_testbusiness.industryPhantoms ImagingMicrocirculationMagnetic resonance imagingPulse sequenceMagnetic Resonance ImagingNuclear medicinebusinessPerfusionJournal of magnetic resonance imaging : JMRI
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Association between C1019T polymorphism of connexin37 and acute myocardial infarction: a study in patients from Sicily

2003

Abstract During atherogenesis, a critical role is played by intercellular communication via gap junctions, cell membrane channels linking the cytoplasmic compartments of adjacent cells. The component protein subunits of these channels, called connexin (Cx), belong to a multigene family. Cx37 is involved in growth, regeneration after injury and ageing of the endothelial cells, suggesting its role in atherosclerosis. The C1019 single nucleotide polymorphism (SNP) of Cx37 gene was associated with thickening of the carotid intima in Swedish men and was also associated with coronary artery disease in a Taiwanese population. On the other hand, in two more recent studies performed in male Japanese…

AdultGenetic MarkersMalemedicine.medical_specialtyPathologyGenotypeHeart diseasePopulationMyocardial InfarctionSingle-nucleotide polymorphismPolymerase Chain ReactionPolymorphism Single NucleotideGastroenterologyConnexinsCoronary artery diseaseGene FrequencyRisk FactorsInternal medicineOdds RatioHumansMedicineSNPMyocardial infarctioneducationSicilyRetrospective Studieseducation.field_of_studybusiness.industryIncidenceCase-control studyDNAOdds ratioMiddle Agedmedicine.diseasePhenotypeCardiology and Cardiovascular MedicinebusinessInternational Journal of Cardiology
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Staying Active under Restrictions: Changes in Type of Physical Exercise during the Initial COVID-19 Lockdown

2021

Copyright: © 2021 by the authors. The COVID-19 pandemic and the associated governmental restrictions suddenly changed everyday life and potentially affected exercise behavior. The aim of this study was to explore whether individuals changed their preference for certain types of physical exercise during the pandemic and to identify risk factors for inactivity. An international online survey with 13,881 adult participants from 18 countries/regions was conducted during the initial COVID-19 related lock-down (between April and May 2020). Data on types of exercise performed during and before the initial COVID-19 lockdown were collected, translated, and categorized (free-text input). Sankey chart…

AdultGerontologyHealth Toxicology and MutagenesiscoronavirusPsychological interventionphysical activityContext (language use)Physical exerciseFootball790 Sports games & entertainmentliikuntaPhysical strengthArticlelockdownstay-at-homeHumansrisk factorsEveryday lifeExercisePandemicssopeutuminenSARS-CoV-2Social distanceRPublic Health Environmental and Occupational HealthCOVID-19structured exercisekansainvälinen vertailu790 Sports games & entertainmentinactivitypoikkeusolotCommunicable Disease ControlMedicineRural areaPsychologyfyysinen aktiivisuus
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Atrial fibrillation management: A prospective survey in ESC Member Countries - The Euro Heart Survey on atrial fibrillation

2005

Aims To describe atrial fibrillation (AF) management in member countries of the European Society of Cardiology (ESC) and to verify cardiology practices against guidelines. Methods and results Among 182 hospitals in 35 countries, 5333 ambulant and hospitalized AF patients were enrolled, in 2003 and 2004. AF was primary or secondary diagnosis, and was confirmed on ECG in the preceding 12 months. Clinical type of AF was reported to be first detected in 978, paroxysmal in 1517, persistent in 1167, and permanent in 1547 patients. Concomitant diseases were present in 90% of all patients, causing risk factors for stroke to be also highly prevalent (86%). As many as 69% of patients were symptomatic…

AdultHeart FailureMaleRate controlRisk FactorCardiologyCoronary Artery DiseaseGuidelineMiddle AgedAtrial fibrillationEuropeStrokeAnticoagulationProspective StudieAnti-Arrhythmia AgentEchocardiographyHypertensionPractice Guidelines as TopicRhythm controlFemaleSocieties MedicalAgedHuman
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Addressing the impact of SARS-CoV-2 infection in persons with congenital bleeding disorders: The Italian MECCOVID-19 study

2021

congenital bleeding disorders

AdultInheritedMalePediatricsmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)congenital bleeding disorderscongenital bleeding disorderSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)haemophiliaHemorrhageHaemophiliaLetter to the EditorsSARS‐CoV‐2Young AdultBlood Coagulation Disorders InheritedCOVID‐19congenital bleeding disorders; COVID-19; epidemiology; haemophilia; observational study; SARS-CoV-2; Adult; Aged; Blood Coagulation Disorders Inherited; COVID-19; Child Preschool; Disease Management; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; SARS-CoV-2; Young AdultEpidemiologymedicineHumansYoung adultDisease management (health)ChildPreschoolLetter to the EditorGenetics (clinical)Agedbusiness.industrySARS-CoV-2COVID-19Disease ManagementHematologyGeneral MedicineBlood Coagulation DisordersMiddle Agedmedicine.diseaseItalySARS-CoV-2.Child PreschoolObservational studyepidemiologyobservational studyFemalebusiness
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Inflammatory markers and cardiovascular risk in the metabolic syndrome

2011

Elevated blood glucose, obesity, high blood pressure, elevated triglycerides and low high density lipoprotein (HDL) cholesterol are well accepted risk factors in the development of coronary artery disease. Clustering of at least three of these factors in an individual is defined as metabolic syndrome (MetS). Obesity is a central pathological mechanism in the disease and it is expected that the incidence of this condition will increase dramatically within the next years. The visceral adipose tissue is not only an energy depot but also an endocrine organ which produces a large number of bioactive molecules, the so called adipokines. In the setting of obesity, the over-production of proinflamm…

AdultLeptinRiskAdolescentAngiotensinogenAdipokineAdipose tissueDiseaseIntra-Abdominal FatBioinformaticsCoronary artery diseasePathogenesisInsulin resistancePlasminogen Activator Inhibitor 1medicineHumansResistinObesityLife StyleChemokine CCL2InflammationMetabolic SyndromeInterleukin-6Tumor Necrosis Factor-alphabusiness.industryAtherosclerosisPrognosismedicine.diseaseObesityPlaque AtheroscleroticCardiovascular DiseasesAdiponectinEndothelium VascularInsulin ResistanceMetabolic syndromebusinessBiomarkersFrontiers in Bioscience
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Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study

2022

Breast milk is a vehicle to transfer protective antibodies from the lactating mother to the neonate. After SARS-CoV-2 infection, virus-specific IgA and IgG have been identified in breast milk, however, there are limited data on the impact of different COVID-19 vaccine types in lactating women. This study is aimed to evaluate the time course of induction of SARS-CoV-2-specific IgA and IgG in breast milk after vaccination.

AdultLongitudinal studyBreast milkCOVID-19 VaccinesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BreastfeedingimmunoglobulinsImmunoglobulinsBreast milkAntibodies ViralVacunesAntibodiesVirusPersistence (computer science)ChAdOx1 nCoV-19GeneticsHumansLactationMedicineantibodiesLongitudinal Studiesskin and connective tissue diseasesMolecular BiologyBNT162 VaccineGenetics (clinical)Milk Humanbiologybusiness.industrySARS-CoV-2VaccinationInfant Newbornfood and beveragesInfantCOVID-19vaccinesImmunoglobulin AVaccinationLlet maternaImmunoglobulin GImmunologybiology.proteinMolecular Medicinebreast milkFemaleAntibodybusiness
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Are Asthmatics Enrolled in Randomized Trials Representative of Real-Life Outpatients?

2014

<b><i>Background/Objective:</i></b> This study was aimed at exploring to what extent populations enrolled in randomized controlled trials (RCTs) of inhalation combination treatment for mild/moderate asthma in adults are fully representative of ‘real-life' populations. The following is a retrospective analysis of the clinical records of outpatient subjects with an ascertained diagnosis of asthma. <b><i>Methods:</i></b> A retrospective analysis was performed. Stable conditions, such as smoking habit and chronic diseases other than asthma, were identified as exclusion criteria for RCTs. The selected criteria were then applied to asthmatic outpati…

AdultLung DiseasesMalePulmonary and Respiratory Medicinemedicine.medical_specialtyPediatricsAdolescentResearch SubjectsAlternative medicineMEDLINECoronary Artery DiseaseAnxietySettore MED/10 - Malattie Dell'Apparato Respiratoriolaw.inventionYoung AdultRandomized controlled triallawmedicineHumansYoung adultAgedRandomized Controlled Trials as TopicRetrospective StudiesAsthmaAged 80 and overInhalationDepressionbusiness.industryPatient SelectionSmokingAge FactorsReal-lifeArrhythmias CardiacRetrospective cohort studyMiddle Agedmedicine.diseaseAsthmaRandomized controlled trialFemaleObservational studybusiness
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Haplotypes of the caspase-1 gene, plasma caspase-1 levels, and cardiovascular risk.

2006

Caspase-1 processes the interleukin (IL)-1β and IL-18 inactive precursors to the biologically active cytokines that are known to have proatherogenic effects. The present study investigated the genetic variability of the CASP1 gene and plasma levels of caspase-1 in relation to cardiovascular risk. In Europeans, 3 tag SNPs captured 4 common haplotypes of the CASP1 gene. Among these, the A in6 allele of the G+7/in6A polymorphism was less frequent in 246 cases with myocardial infarction and a parental history of disease than in 253 controls free of familial history of disease (0.13±0.02 versus 0.20±0.02; P =0.005). However, in a larger case/control study (n=1774), these effects are borderline …

AdultMale/dk/atira/pure/subjectarea/asjc/1300/1314medicine.medical_specialtyPathologyGenotypePhysiologyPopulationMyocardial Infarction/dk/atira/pure/subjectarea/asjc/2700/2705Single-nucleotide polymorphismCoronary Artery DiseaseBiologyPolymorphism Single NucleotideRisk AssessmentCoronary artery diseaseCohort StudiesGene FrequencyPolymorphism (computer science)Internal medicinemedicineHumansGenetic Predisposition to DiseaseProspective StudiesAlleleeducationProspective cohort studyAgededucation.field_of_studyVascular diseaseHazard ratioCaspase 1Interleukin-18Genetic VariationMiddle Agedmedicine.diseaseEndocrinologyHaplotypesCardiovascular DiseasesCase-Control StudiesFemaleCardiology and Cardiovascular MedicineFollow-Up StudiesCirculation research
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Effect of incision design on interproximal bone loss of teeth adjacent to single implants. A randomized controlled clinical trial comparing intrasulc…

2018

PURPOSE To evaluate the effect of incision design in implant surgery on interproximal bone loss of posterior teeth adjacent to interdental single implants, comparing intrasulcular and paramarginal incision. A further aim was to assess the influence of the incision technique on peri-implant bone remodeling. MATERIALS AND METHODS A controlled randomized clinical trial was carried out in a University Clinic. All the patients received an interdental posterior single implant. The incision type was randomly divided into two groups: (a) intrasulcular or (b) paramarginal. Standardized periapical digital radiographs were made with the parallel technique and a silicone index individualized in each pa…

AdultMale0301 basic medicineAlveolar Bone LossDentistryBone remodelingYoung Adult03 medical and health sciencesDental Implants Single-Tooth0302 clinical medicineDouble-Blind MethodBone-Implant InterfaceRadiography DentalHumansMedicineAgedAged 80 and overbusiness.industryDental Implantation EndosseousInterdental consonant030206 dentistryPeriodontologyMiddle AgedCementoenamel junction030104 developmental biologyCoronal planePosterior teethFemaleBone RemodelingImplantOral SurgerybusinessAbutment (dentistry)Clinical Oral Implants Research
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