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RESEARCH PRODUCT
Dynamic contrast-enhanced myocardial perfusion imaging using saturation-prepared TrueFISP.
Manfred ThelenMelanie SchmittOliver K. MohrsWolfgang SchreiberKarl-friedrich KreitnerP. Kaldensubject
AdultGadolinium DTPAMaterials scienceImage qualityContrast MediaImage processingStatistics NonparametricMyocardial perfusion imagingNuclear magnetic resonancePrecontrastCoronary CirculationmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingImage resolutionmedicine.diagnostic_testbusiness.industryPhantoms ImagingMicrocirculationMagnetic resonance imagingPulse sequenceMagnetic Resonance ImagingNuclear medicinebusinessPerfusiondescription
Purpose To develop and test a saturation-recovery TrueFISP (SR-TrueFISP) pulse sequence for first-pass myocardial perfusion imaging. Materials and Methods First-pass magnetic resonance imaging (MRI) of Gd-DTPA (2 mL) kinetics in the heart was performed using an SR-TrueFISP pulse sequence (TR/TE/α = 2.6 msec/1.4 msec/55°) with saturation preparation TD = 30 msec before the TrueFISP readout. Measurements were also performed with a conventional saturation-recovery TurboFLASH (SRTF) pulse sequence for comparison. Results SR-TrueFISP images were of excellent quality and demonstrated contrast agent wash-in more clearly than SRTF images. The signal increase in myocardium was higher in SR-TrueFISP than in SRTF data. Precontrast SNR and peak CNR were not significantly different between both sequences despite 57% improved spatial resolution for SR-TrueFISP. Conclusion SR-TrueFISP first-pass MRI of myocardial perfusion leads to a substantial improvement of image quality and spatial resolution. It is well suited for first-pass myocardial perfusion studies at cardiovascular MR systems with improved gradient hardware. J. Magn. Reson. Imaging 2002;16:641–652. © 2002 Wiley-Liss, Inc.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2002-11-25 | Journal of magnetic resonance imaging : JMRI |