Search results for "cyclic"

showing 10 items of 2439 documents

Reaktionen von Benzothiet mit Iminen

1993

Reactions of Benzothiete with Imines A great variety of compounds 3a–w containing CN double bonds was studied in the reaction with benzothiete (1). H, alkyl, aryl, OR, SR and NR groups can be attached to the imino function. The azomethines 3a–f, the thiazolines 3g–i, the lactim 3n, the oximes 3r–t, the isoxazolinone 3u and the azine 3v show [8π + 2π] cycloaddition reactions yielding derivatives of 1,3-benzothiazine (4a–i, n, r–v). In the case of 4n, s, t secondary reactions occur, initiated by elimination processes. [8π + 2π] Cycloadditions account also for the reactions 3e 10, 11, 3o 18(I), and 3q 19; however, CC double bonds are representing the 2π component in these examples. The thiazol…

chemistry.chemical_classificationSteric effectsBicyclic moleculeDouble bondChemistryStereochemistryThiazolineOrganic ChemistryHydrazoneTautomerMedicinal chemistryCycloadditionAzinechemistry.chemical_compoundPhysical and Theoretical ChemistryLiebigs Annalen der Chemie
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ChemInform Abstract: Asymmetric Synthesis of Bicyclic Amino Acid Derivatives by Aza-Diels- Alder Reactions in Aqueous Solution.

2010

Derivatives 7–10 and 13–16 of methyl and ethyl 2-azabicyclo[2.2.1]heptane-3-carboxylates are synthesized by Aza-Diels-Alder reactions of chiral iminium ions, formed in situ from glyoxylic acid and chiral amines, with cyclopentadiene. Whereas the heterodienophiles derived from phenylglycinol and esters of sterically more demanding amino acids fail to undergo asymmetric cycloadditions, with alanine methyl ester and (R)-1-phenylethylamine hydrochoride the cycloadducts are formed in yields of 15 and 52%, respectively, reaching de values of up to 90:10 for the exo isomers.

chemistry.chemical_classificationSteric effectschemistry.chemical_compoundAqueous solutionCyclopentadieneBicyclic moleculeChemistryEnantioselective synthesisIminiumGeneral MedicineMedicinal chemistryGlyoxylic acidAmino acidChemInform
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Naphthalenophane durch doppelte Photocyclodimerisierung von Distyrylnaphthalinen

1989

Bei der Belichtung von Distyrylnaphthalinen entstehen in regiospezifischen Kopf-Kopf-Cycloadditionen Naphthalenophane. Je nach Stellung der Styryl-Gruppen beobachtet man vollkommen stereospezifische Prozesse (1d 2, 1g 3, 1h 4) und Dimerisierungen mit partiellen Stereoselektivitaten (1b 5–8, 1i 9, 10). Masgeblich sind die Rotamerenpopulation im Ausgangsprodukt 1 und die elektronischen und sterischen Effekte in den Excimeren. Prinzipiell sind Excimere mit paralleler Anordnung moglichst vieler π-Zentren bevorzugt — ein experimenteller Befund, der durch HMO-Rechnungen untermauert wird. Naphthalenophanes by Twofold Photocyclodimerizatio Reactions of Distyrylanaphthalenes Regiospecific head-to-he…

chemistry.chemical_classificationSteric effectseducation.field_of_studyStereochemistryPopulationCycloadditionInorganic Chemistrychemistry.chemical_compoundPolycyclic compoundchemistryParallel arrangementeducationConformational isomerismCyclophaneChemische Berichte
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Reaktion von elektronenreichen Heterocyclen mit Orthocarbonsäure-Derivaten, 12. Formylierung von Vinylindolen mit Diethoxycarbenium-tetrafluoroborat

1988

Reactions of Electron-Rich Heterocycles with Orthocarboxylic Acid Derivatives, 12. – Formylation of Vinylindoles with Diethoxycarbenium Tetrafluoroborate 2- and 3-vinylindoles 1, 3 are formylated with diethoxycarbenium tetrafluoroborate regioselectively. The significant selectivity and reactivity of formylation of diethoxycarbenium ion in comparison with other thermodynamically more stable dialkoxycarbenium ions are compatible with the known results of hetaryl functionalisation with orthocarboxylic acid derivatives.

chemistry.chemical_classificationTetrafluoroborateBicyclic moleculeOrganic ChemistryRegioselectivityAldehydeMedicinal chemistryFormylationchemistry.chemical_compoundchemistryOrganic chemistryReactivity (chemistry)Physical and Theoretical ChemistrySelectivityLiebigs Annalen der Chemie
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A novel and selective fluoride opening of aziridines by XtalFluor-E. synthesis of fluorinated diamino acid derivatives.

2015

The selective introduction of fluorine onto the skeleton of an aminocyclopentane or cyclohexane carboxylate has been developed through a novel and efficient fluoride opening of an activated aziridine ring with XtalFluor-E. The reaction proceeded through a stereoselective aziridination of the olefinic bond of a bicyclic lactam and regioselective aziridine ring opening with difluorosulfiliminium tetrafluoroborate with the neighboring group assistance of the sulfonamide moiety to yield fluorinated diamino acid derivatives. The method based on the selective aziridine opening by fluoride has been generalized to afford access to mono- or bicyclic fluorinated substances.

chemistry.chemical_classificationTetrafluoroborateBicyclic moleculesynthesisOrganic ChemistryRegioselectivitycarboxylatesAziridineBiochemistryMedicinal chemistrySulfonamidechemistry.chemical_compoundchemistryaziridinesfluorineLactamMoietyOrganic chemistryPhysical and Theoretical ChemistryFluorideta116Organic letters
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New Studies and a Reinvestigation on [4+2] Cycloadditions of (−)-Thebaine: Asymmetrical Diels-Alder Reactions with a Conformationally Fixed Chiral Di…

1993

Some novel Diels-Alder reactions of the opium alkaloid (−)-thebaine (1) as an electron-rich diene and a reinvestigation of its reactions with cyclic and acyclic dienophiles are described. The π-facial selectivity has been studied on the basis of structural analyses of the cycloadducts. Some related results on [4 + 2] cycloaddition reactions of 1-methoxy-1,3-cyclohexadiene (11) are also reported.

chemistry.chemical_classificationThebaineDieneAlkaloidOrganic ChemistryOpiumMedicinal chemistryCycloadditionchemistry.chemical_compoundPolycyclic compoundchemistrymedicineStereoselectivityPhysical and Theoretical ChemistrySelectivitymedicine.drugLiebigs Annalen der Chemie
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Transition metal–saccharide chemistry: synthesis, characterization and solution stability studies of cis-dioxomolybdenum saccharide complexes

1998

Six cis-dioxomolybdenum(VI) complexes of simple monosaccharides (D-glucose, D-fructose, D-galactose, D-mannose, D-ribose and D-xylose) have been synthesized and characterized by a variety of analytical and spectral methods. Both the solution and solid-state studies have supported the presence of dimeric structures, formed through the cis-MoO2 moieties and the bridging saccharide units. Solution stability of these complexes as a function of time has also been addressed.

chemistry.chemical_classificationThermal AnalysisCircular dichroismSpectrometersStereochemistryCircular DichroismOrganic ChemistryMannoseFructoseGeneral MedicineXyloseBiochemistryAnalytical Chemistrychemistry.chemical_compoundchemistryTransition metalGalactoseRiboseOrganic chemistryMonosaccharideCyclic VoltammetryIndraStra Global
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Synthesis, structure, physicochemical characterization and theoretical evaluation of non-covalent interaction energy of a polymeric copper(II)-hydraz…

2019

Abstract One dimensional polymeric copper-hydrazone complex {[Cu(H0.5L)(µ1,3-SCN)]0.5ClO4·0.5MeOH}n (1) has been synthesized with Cu(ClO4)2·xH2O and N'-(1-(pyridin-2-yl)ethylidene)acetohydrazide (HL) in presence of NaSCN. The ligand and the complex have been characterized by several spectroscopic techniques (IR, UV–Vis and EPR), cyclic voltammetry and the structure of 1 has been determined by single crystal X-ray diffraction. The complex is an infinite one dimensional polymer bridged by thiocyanate. The magneto-structural correlation has been determined and the non-covalent interactions present in the molecule have been energetically evaluated by means of DFT calculations.

chemistry.chemical_classificationThiocyanateChemistryLigandHydrazoneInteraction energylaw.inventionInorganic Chemistrychemistry.chemical_compoundCrystallographylawMaterials ChemistryMoleculePhysical and Theoretical ChemistryCyclic voltammetryElectron paramagnetic resonanceSingle crystalInorganica Chimica Acta
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Selective Formal Transesterification of Fluorinated 2-(Trimethylsilyl)ethyl α-Imino Esters Mediated by TBAF

2008

The scope of the transesterification reaction between beta-fluorinated alpha-imino esters and various electrophiles in the presence of TBAF as fluorine source is described. The reaction is highly selective for alkyl iodides, bromides, and mesylates, while alkyl chlorides react at a significantly slower rate and tosylates do not react under the reaction conditions. This methodology represents a simple and useful alternative for the preparation of a wide variety of fluorinated alpha-imino esters.

chemistry.chemical_classificationTrimethylsilylChemistryOrganic Chemistrychemistry.chemical_elementTransesterificationChemical synthesisReaction ratechemistry.chemical_compoundElectrophileFluorineOrganic chemistryheterocyclic compoundsSelectivityAlkylThe Journal of Organic Chemistry
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Determination of selected polyaromatic hydrocarbons by gas chromatography–mass spectrometry for the analysis of wood to establish the cause of sinkin…

2014

Abstract The aim of this paper was to establish the cause of sinking of an old wooden vessel by polycyclic aromatic hydrocarbon (PAH) analyses because wood combustion is a source of PAHs. In particular, the molecular PAH patterns generated by each source are like fingerprints and it is possible to determine the processes that generate PAHs by studying their distribution in wood samples. The relative abundance of high molecular weight PAHs, together with the PAH compound ratios and with total index (proposed by us) has demonstrated that samples owe their PAHs in wood archaeological material to a predominant single mode of origin, i.e. combustion processes, therefore we can say that the sinki…

chemistry.chemical_classificationVesselChemistryPolycyclic aromatic hydrocarbonArchaeologicalArchaeologicalVesselFirePAHsFireCombustionSettore CHIM/12 - Chimica Dell'Ambiente E Dei Beni CulturaliAnalytical ChemistryPAHsEnvironmental chemistrypolycyclic compoundsSettore CHIM/01 - Chimica AnaliticaGas chromatography–mass spectrometrySpectroscopyMicrochemical Journal
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