Search results for "ddc:0"
showing 10 items of 65 documents
Including the Past: Performance Modeling Using a Preload Concept by Means of the Fitness-Fatigue Model
2019
Abstract In mathematical modeling by means of performance models, the Fitness-Fatigue Model (FF-Model) is a common approach in sport and exercise science to study the training performance relationship. The FF-Model uses an initial basic level of performance and two antagonistic terms (for fitness and fatigue). By model calibration, parameters are adapted to the subject’s individual physical response to training load. Although the simulation of the recorded training data in most cases shows useful results when the model is calibrated and all parameters are adjusted, this method has two major difficulties. First, a fitted value as basic performance will usually be too high. Second, without mo…
Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer
2018
Microsatellite instability (MSI) leads to accumulation of an excessive number of mutations in the genome, mostly small insertions and deletions. MSI colorectal cancers (CRCs), however, also contain more point mutations than microsatellite-stable (MSS) tumors, yet they have not been as comprehensively studied. To identify candidate driver genes affected by point mutations in MSI CRC, we ranked genes based on mutation significance while correcting for replication timing and gene expression utilizing an algorithm, MutSigCV. Somatic point mutation data from the exome kit-targeted area from 24 exome-sequenced sporadic MSI CRCs and respective normals, and 12 whole-genome-sequenced sporadic MSI CR…
Diffusion of Drone Journalism: the Case of Finland, 2011-2020
2020
This article details Finnish news organizations’ adoption of drones for journalistic purposes from 2011 to 2020. The theoretical starting point of the article is Rogers’ (1962) diffusion of innovations theory, which explains how new ideas and technologies spread in societies. The main empirical data for the study were derived from a phone survey conducted among the 80 most popular newspapers in Finland. The findings reveal that drone journalism in Finland has already diffused from a few pioneering organizations to a large number of newsrooms, including regional, mid-sized newspapers. Most of the newspapers are either using in-house drones, buying commissioned images, or using both strategie…
BIOfid dataset: publishing a German gold standard for named entity recognition in historical biodiversity literature
2019
The Specialized Information Service Biodiversity Research (BIOfid) has been launched to mobilize valuable biological data from printed literature hidden in German libraries for over the past 250 years. In this project, we annotate German texts converted by OCR from historical scientific literature on the biodiversity of plants, birds, moths and butterflies. Our work enables the automatic extraction of biological information previously buried in the mass of papers and volumes. For this purpose, we generated training data for the tasks of Named Entity Recognition (NER) and Taxa Recognition (TR) in biological documents. We use this data to train a number of leading machine learning tools and c…
Fuzzy subgroup mining for gene associations
2004
When studying the therapeutic efficacy of potential new drugs, it would be much more efficient to use predictors in order to assess their toxicity before going into clinical trials. One promising line of research has focused on the discovery of sets of candidate gene profiles to be used as toxicity indicators in future drug development. In particular genomic microarrays may be used to analyze the causality relationship between the administration of the drugs and the so-called gene expression, a parameter typically used by biologists to measure its influence at gene level. This kind of experiments involves a high throughput analysis of noisy and particularly unreliable data, which makes the …
Measurement, Prediction, and Control of Individual Heart Rate Responses to Exercise-Basics and Options for Wearable Devices.
2018
The use of wearable devices or "wearables" in the physical activity domain has been increasing in the last years. These devices are used as training tools providing the user with detailed information about individual physiological responses and feedback to the physical training process. Advantages in sensor technology, miniaturization, energy consumption and processing power increased the usability of these wearables. Furthermore, available sensor technologies must be reliable, valid, and usable. Considering the variety of the existing sensors not all of them are suitable to be integrated in wearables. The application and development of wearables has to consider the characteristics of the p…
Removing krypton from xenon by cryogenic distillation to the ppq level
2017
The XENON1T experiment aims for the direct detection of dark matter in a detector filled with 3.3 tons of liquid xenon. In order to achieve the desired sensitivity, the background induced by radioactive decays inside the detector has to be sufficiently low. One major contributor is the β-emitter 85Kr which is present in the xenon. For XENON1T a concentration of natural krypton in xenon natKr/Xe<200ppq (parts per quadrillion, 1ppq=10-15mol/mol) is required. In this work, the design, construction and test of a novel cryogenic distillation column using the common McCabe–Thiele approach is described. The system demonstrated a krypton reduction factor of 6.4 · 10 5 with thermodynamic stability a…
Glimmering utopias: 50 years of African film
2010
The history of African film began in the 1960s with the independence of the colonies. Despite all kinds of political and economic difficulties, numerous films have been made since then, featuring wide-ranging processes of consolidation, differentiation and transformation which were characteristic of post-colonial sub-Saharan Africa. However, these feature films should not merely be viewed as back references to specifically African problems. The glimmering fictions are imagination spaces. They preserve ideas about how the post-colonial circumstances should be approached. Seen from this perspective, the history of African film may be studied as a history of African utopias. Die Geschichte des…
FO^2 with one transitive relation is decidable
2013
We show that the satisfiability problem for the two-variable first-order logic, FO^2, over transitive structures when only one relation is required to be transitive, is decidable. The result is optimal, as FO^2 over structures with two transitive relations, or with one transitive and one equivalence relation, are known to be undecidable, so in fact, our result completes the classification of FO^2-logics over transitive structures with respect to decidability. We show that the satisfiability problem is in 2-NExpTime. Decidability of the finite satisfiability problem remains open.
The complexity of finite model reasoning in description logics
2005
AbstractWe analyse the complexity of finite model reasoning in the description logic ALCQI, i.e., ALC augmented with qualifying number restrictions, inverse roles, and general TBoxes. It turns out that all relevant reasoning tasks such as concept satisfiability and ABox consistency are ExpTime-complete, regardless of whether the numbers in number restrictions are coded unarily or binarily. Thus, finite model reasoning with ALCQI is not harder than standard reasoning with ALCQI.