Search results for "death"

showing 10 items of 1744 documents

Taste, movement, and death: varying effects of new prospero mutants during Drosophila development

2003

0022-3034 (Print) Comparative Study Journal Article Research Support, Non-U.S. Gov't; The PGal4 transposon inserted upstream of the pan-neural gene prospero (pros) causes several neural and behavioral defects in the Voila(1) strain. The precise excision of the transposon simultaneously rescued all these defects whereas its unprecise excision created new pros(V) alleles, including the null allele pros(V17). Here, we describe the relationship between the genetic structure of pros locus, larval locomotion, and larval gustatory response. These two behaviors showed varying degrees of variation depending upon the pros allele. We also found a good relation between behavioral alteration, the level …

GenotypeNerve Tissue Proteins/*genetics/metabolismeducationLethalMovement/*physiologyTaste/*geneticsDrosophila melanogaster/embryology/genetics/growth & developmentReaction TimeAnimalsDrosophila ProteinsNeuromuscular Junction/genetics/growth & development/metabolismSouthernLarva/genetics/*growth & developmentAllelesNonmammalianNuclear Proteins/*genetics/metabolismBlottingDevelopmental/physiologyImmunohistochemistryhumanitiesGenomics/methodsDeathInvertebrate/chemistryGene Expression RegulationGenesEmbryoMutationDNA Transposable ElementsGangliaInsectTranscription Factors
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The effect of particulate air pollution on life expectancy.

1998

Two recent US cohort studies suggest that current levels of particulate pollution in urban air are associated not only with short-term, but also with long-term increases in cardiorespiratory morbidity and mortality. The aim of the present analyses was to evaluate the change in life expectancy assuming the long-term increase in mortality rates as suggested by these studies. The method of competing causes of death was used and the effect of particulate air pollution on life expectancy was found to be notable in countries with high cardiovascular mortality like the US.

GerontologyAdultMaleEnvironmental EngineeringAdolescentAir pollutionmedicine.disease_causeCohort StudiesLife ExpectancyEnvironmental healthAir PollutionCause of DeathEnvironmental ChemistryMedicineHumansParticle SizeChildWaste Management and DisposalFinlandCardiovascular mortalityAgedbusiness.industryMortality rateParticulate pollutionInfant NewbornInfantCardiorespiratory fitnessMiddle AgedParticulate air pollutionPollutionUnited StatesCardiovascular DiseasesChild PreschoolLife expectancyFemalebusinessCohort studyThe Science of the total environment
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Combined associations of body weight and lifestyle factors with all cause and cause specific mortality in men and women: prospective cohort study

2016

Objective  To evaluate the combined associations of diet, physical activity, moderate alcohol consumption, and smoking with body weight on risk of all cause and cause specific mortality. Design  Longitudinal study with up to 32 years of follow-up. Setting  Nurses’ Health Study (1980-2012) and Health Professionals Follow-up Study (1986-2012). Participants  74 582 women from the Nurses’ Health Study and 39 284 men from the Health Professionals Follow-up Study who were free from cardiovascular disease and cancer at baseline. Main outcome measures  Exposures included body mass index (BMI), score on the alternate healthy eating index, level of physical activity, smoking habits, and alcohol drink…

GerontologyAdultMaleStatistics as TopicDisease030204 cardiovascular system & hematologyLower riskBody Mass IndexCohort Studies03 medical and health sciences0302 clinical medicineSex FactorsBiasEnvironmental healthNeoplasmsCause of DeathDiabetes MellitusMedicineHealth Status IndicatorsHumans030212 general & internal medicineLongitudinal StudiesProspective StudiesProspective cohort studyf body weightLife StyleCause of deathAged2. Zero hungerbusiness.industryResearchHazard ratioBody WeightAdult; Aged; Bias (Epidemiology); Body Mass Index; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus Type 2; Female; Health Status Indicators; Health Surveys; Humans; Longitudinal Studies; Male; Middle Aged; Neoplasms; Prospective Studies; Sex Factors; Statistics as Topic; United States; Body Weight; Cause of Death; Life Stylelifestyle factorsGeneral MedicineMiddle AgedHealth SurveysConfidence intervalUnited States3. Good healthDiabetes Mellitus Type 2Cardiovascular DiseasesBias (Epidemiology)FemalebusinessBody mass indexType 2Cohort study
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Testing a new health indicator: using avoidable causes of death and life expectancy for Spain between 1975-1986.

1993

The concept of avoidable cause of death serves as the basis for measuring the quality and diversity of a health care system. In this study the authors propose a new way to use this kind of mortality by combining with the concept of life expectancy to obtain what they call "life expectancy free of avoidable mortality" (LEFAM). This indicator was 76.9 in 1986 in Spain while life expectancy was 75.83. If these deaths were avoidable there would be a gain of 1.09 years per person born. There is an important difference between the would-be male gain of 1.76 years and the would-be female gain of 0.6. In the ecological study, LEFAM would better explain the year to year changes of the resources in t…

GerontologyAdultMalemedicine.medical_specialtyAdolescentEpidemiologyAvoidable mortalityLife ExpectancyCause of DeathHealth careEpidemiologymedicineHealth Status IndicatorsHumansLife TablesChildCause of deathQuality of Health Carebusiness.industryPublic healthInfantMiddle AgedHealth indicatorCausalitySpainChild PreschoolLife expectancyFemalebusinessEuropean journal of epidemiology
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Preference for place of death in Germany.

2011

Dying in the preferred place is considered a key requirement for a "good death." The aims of our study were to explore preferred places of death of deceased people and their bereaved relatives in Rhineland-Palatinate (Germany). We further wanted to assess the congruence between preferred and actual place of death.The cross-sectional study was based on a random sample of 5000 inhabitants of Rhineland-Palatinate (Germany) who died between May 25 and August 24, 2008. Relatives of these deceased persons were interviewed by a written survey.After removing duplicates, 4967 questionnaires were sent out, 3832 delivered, and 1378 completed, yielding a response rate of 36.0%. Regarding the deceased, …

GerontologyAdultMalemedicine.medical_specialtyPalliative careAttitude to DeathAdolescentDecision MakingYoung AdultGermanySurveys and QuestionnairesmedicineConfidence IntervalsOdds RatioHumansChildGeneral NursingAgedRetrospective StudiesAged 80 and overGeographybusiness.industryCommunicationData CollectionInfant NewbornInfantPatient PreferenceGeneral MedicineMiddle AgedAnesthesiology and Pain MedicinePlace of deathFamily medicineChild PreschoolFemalebusinessNursing homesJournal of palliative medicine
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Attitudes Among Patients With Advanced Cancer Toward Euthanasia and Living Wills

2015

Euthanasia has been invariably discussed throughout Europe. In some countries, euthanasia has been legalized under specific conditions that must be fulfilled. These include a properly reported request to be considered carefully, unbearable suffering, no other reasonable alternatives, and a consultation with an independent physician. A living will, also called an advance directive, is a written document that allows a patient to give explicit instructions about medical treatments to be administered when the patient is terminally ill and unable to communicate. In Italy, euthanasia remains illegal, and living wills are not used. These issues have been the subject of constant debate.2 Such discu…

GerontologyAttitude to DeathLiving WillsSettore MED/42 - Igiene Generale E Applicata03 medical and health sciences0302 clinical medicineNeoplasmsHumansMedicinePsychological testing030212 general & internal medicineGeneral NursingNursing (all)2901 Nursing (miscellaneous)Psychological Testsbusiness.industryEuthanasiaAdvanced cancerPsychological TestLiving WillsAnesthesiology and Pain Medicine030220 oncology & carcinogenesisNeoplasmNeurology (clinical)businessAttitude to HealthLiving WillHuman
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Physical activity history and end-of-life hospital and long-term care

2009

Background: Little is known about the early predictors of need for care in late life. The purpose of this study was to investigate whether physical activity from midlife onward was associated with hospital and long-term care in the last year of life. Methods: We studied a decedent population of 846 persons aged 66–98 years at death, who, on average 5.8 years prior to death, had participated in an interview about their current and earlier physical activity. Data on the use of care in the last year of life are register-based data and complete. Results: Men needed on average 96 days (SD 7.0) and women 138 days (SD 6.2) of inpatient care in the last year of life. Among men, the risk for all-cau…

GerontologyMaleAgingPopulationpitkäaikaishoitoPhysical activityikääntyneet henkilötphysical activitysairaalahoitoRate ratioRisk AssessmentlaitoshoitoAge DistributionRisk FactorsCause of DeathSurveys and QuestionnairesHealth careActivities of Daily LivingConfidence IntervalsOdds RatioMedicineHomes for the AgedHumansMiddle-aged adultProspective StudiesSex DistributioneducationGeriatric AssessmentFinlandAgedAged 80 and overeducation.field_of_studyInpatient carebusiness.industryData CollectionIncidenceLength of StayLong-Term CareHospital careNursing HomesHospitalizationLong-term careagedPhysical FitnessFemaleGeriatrics and Gerontologybusinessfyysinen aktiivisuus
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Body mass index as a predictor of all-cause mortality in nursing home residents during a 5-year follow-up.

2013

Background: Body mass index (BMI) is considered a short-term mortality predictor, but a consensus has not been reached on its role and that of other nutritional parameters in predicting long-term mortality in nursing home residents. Objectives: To correlate BMI, Mini Nutritional Assessment scores, and serum albumin levels with the 5-year mortality rate in institutionalized elderly subjects. Methods: A total of 181 nursing home residents aged ≥70 years were included in a 5-year longitudinal study. Data were collected on all participants' nutritional, health, cognitive, and functional status by means of a comprehensive geriatric assessment. Data on the participants' vital status were obtained…

GerontologyMaleLongitudinal studyComorbiditySeverity of Illness IndexBody Mass IndexPredictive Value of TestsCause of DeathMedicineHumansLongitudinal StudiesBody mass index nursing home mortality elderly nutritionGeriatric AssessmentGeneral NursingSurvival analysisCause of deathAgedProportional Hazards ModelsAged 80 and overbusiness.industryProportional hazards modelHealth PolicyMortality rateGeneral Medicinemedicine.diseaseComorbidityNursing HomesPredictive value of testsLinear ModelsFemaleGeriatrics and GerontologybusinessBody mass indexDemographyFollow-Up StudiesJournal of the American Medical Directors Association
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A high dietary glycemic index increases total mortality in a Mediterranean population at high cardiovascular risk

2014

© 2014 Castro-Quezada et al. Objective: Different types of carbohydrates have diverse glycemic response, thus glycemic index (GI) and glycemic load (GL) are used to assess this variation. The impact of dietary GI and GL in all-cause mortality is unknown. The objective of this study was to estimate the association between dietary GI and GL and risk of all-cause mortality in the PREDIMED study. Material and Methods: The PREDIMED study is a randomized nutritional intervention trial for primary cardiovascular prevention based on community-dwelling men and women at high risk of cardiovascular disease. Dietary information was collected at baseline and yearly using a validated 137-item food freque…

GerontologyMalePhysiologyEpidemiologymodelos de riesgos proporcionaleshumanoslcsh:MedicineDieta mediterràniaFatsElderlyRisk Factorsíndice glucémicoCause of DeathMedicine and Health SciencesMedicinelcsh:Sciencemediana edadAged 80 and overeducation.field_of_studyancianoMultidisciplinaryDeath ratesGeographyGeographical regionsdietaMortality rateHazard ratioRegional geographyAge FactorsMiddle AgedGlycemic indexCardiovascular diseasesQuartilePhysiological ParametersCardiovascular DiseasesFemaleDietaResearch Articlemedicine.medical_specialtyPopulationCarbohydratesenfermedades cardiovascularesBlood sugarNational Death Indexcausas de muerteInternal medicineGlycemic loadDietary CarbohydratesMortalitatHumansfactores de riesgoObesityFatty acidsMortalityeducationCardiovascular Disease EpidemiologyGlycemicNutritionAgedProportional Hazards Modelsconducta alimentariabusiness.industryPhysical activitycarbohidratos dietéticosMalalties cardiovascularslcsh:RBody WeightBiology and Life SciencesPREDIMED studyNutrientsFeeding BehaviorGenitourinary cancersDietEarth sciencesGlucèmiaGeriatricsGlycemic IndexGlycemiclcsh:QMediterranean Basinbusinesshuman activities
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Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk

2013

The relation between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular risk. The aim of this study was to assess the association between magnesium intake and CVD and mortality risk in a Mediterranean population at high cardiovascular risk with high averagemagnesium intake. The present study included 7216 men and women aged 55-80 y fromthe PREDIMED (Prevencíon con Dieta Mediterŕanea) study, a randomized clinical trial. Participants were assigned to 1 of 2 Mediterranean diets (supplemente…

GerontologyMalePopulationMedicine (miscellaneous)DiseaseDiet MediterraneanNational Death Indexlaw.inventionRandomized controlled triallawRisk FactorsEnvironmental healthNeoplasmsMedicineHumansNutsPlant OilsMagnesiumProspective StudiesProspective cohort studyeducationGeneralized estimating equationDiet Fat-RestrictedOlive OilAgedAged 80 and overCancer Death Rateeducation.field_of_studyNutrition and Dieteticsbusiness.industryMediterranean RegionMiddle AgedCardiovascular DiseasesRelative riskDietary SupplementsMultivariate AnalysisFemalebusinessFollow-Up Studies
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