Search results for "delay"
showing 10 items of 814 documents
A Sequential Game Approach for Computation-Offloading in an UAV Network
2017
International audience; Small drones are currently emerging as versatile nascent technology that can be used in exploration and surveillance missions. However, most of the underlying applications require very often complex and time-consuming calculations. Although, the limited resources available onboard the small drones, their mobility, the computation delays and energy consumption make the operation of these applications very challenging. Nevertheless, computation-offloading solutions provide feasible resolves to mitigate the issues facing these constrained devices. In this context, we address in this paper the problem of offloading highly intensive computation tasks, performed by a fleet…
Tracking Control of Networked Multi-Agent Systems Under New Characterizations of Impulses and Its Applications in Robotic Systems
2016
This paper examines the problem of tracking control of networked multi-agent systems with multiple delays and impulsive effects, whose results are applied to mechanical robotic systems. Four kinds of impulsive effects are taken into account: 1) both the strengths of impulsive effects and the number of nodes injected with impulses are time dependent; 2) the strengths of impulsive effects occur according to certain probabilities and the number of nodes under impulsive control is time varying; 3) the strengths of impulses are time varying, whereas the number of nodes with impulses takes place according to certain probabilities; 4) both the strengths of impulses and the number of nodes with imp…
Finite-time stability and stabilisation for a class of nonlinear systems with time-varying delay
2014
This paper is concerned with the problems of finite-time stability FTS and finite-time stabilisation for a class of nonlinear systems with time-varying delay, which can be represented by Takagi–Sugeno fuzzy system. Some new delay-dependent FTS conditions are provided and applied to the design problem of finite-time fuzzy controllers. First, based on an integral inequality and a fuzzy Lyapunov–Krasovskii functional, a delay-dependent FTS criterion is proposed for open-loop fuzzy system by introducing some free fuzzy weighting matrices, which are less conservative than other existing ones. Then, the parallel distributed compensation controller is designed to ensure FTS of the time-delay fuzzy…
Modeling Energy Demand Aggregators for Residential Consumers
2013
International audience; Energy demand aggregators are new actors in the energy scenario: they gather a group of energy consumers and implement a demand- response paradigm. When the energy provider needs to reduce the current energy demand on the grid, it can pay the energy demand aggregator to reduce the load by turning off some of its consumers loads or postponing their activation. Currently this operation involves only greedy energy consumers like industrial plants. In this paper we want to study the potential of aggregating a large number of small energy consumers like home users as it may happen in smart grids. In particular we want to address the feasibility of such approach by conside…
New delay-dependent stability of Markovian jump neutral stochastic systems with general unknown transition rates
2015
This paper investigates the delay-dependent stability problem for neutral Markovian jump systems with generally unknown transition rates GUTRs. In this neutral GUTR model, each transition rate is completely unknown or only its estimate value is known. Based on the study of expectations of the stochastic cross-terms containing the integral, a new stability criterion is derived in terms of linear matrix inequalities. In the mathematical derivation process, bounding stochastic cross-terms, model transformation and free-weighting matrix are not employed for less conservatism. Finally, an example is provided to demonstrate the effectiveness of the proposed results.
DLG4-related synaptopathy: a new rare brain disorder
2021
Contains fulltext : 245031.pdf (Publisher’s version ) (Closed access) PURPOSE: Postsynaptic density protein-95 (PSD-95), encoded by DLG4, regulates excitatory synaptic function in the brain. Here we present the clinical and genetic features of 53 patients (42 previously unpublished) with DLG4 variants. METHODS: The clinical and genetic information were collected through GeneMatcher collaboration. All the individuals were investigated by local clinicians and the gene variants were identified by clinical exome/genome sequencing. RESULTS: The clinical picture was predominated by early onset global developmental delay, intellectual disability, autism spectrum disorder, and attention deficit-hyp…
Alterations in Tau Protein Level and Phosphorylation State in the Brain of the Autistic-Like Rats Induced by Prenatal Exposure to Valproic Acid
2021
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficient social interaction and communication besides repetitive, stereotyped behaviours. A characteristic feature of ASD is altered dendritic spine density and morphology associated with synaptic plasticity disturbances. Since microtubules (MTs) regulate dendritic spine morphology and play an important role in spine development and plasticity the aim of the present study was to investigate the alterations in the content of neuronal α/β-tubulin and Tau protein level as well as phosphorylation state in the valproic acid (VPA)-induced rat model of autism. Our results indicated that maternal exposure to VPA indu…
Mothering under the influence: How perinatal drugs of abuse alter the mother-infant interaction
2018
AbstractAlthough drug-abusing women try to moderate their drug and alcohol use during pregnancy, they often relapse at a time when childcare needs are high and maternal bonding is critical to an infant’s development. In the clinical setting, the search for the neural basis of drug-induced caregiving deficits is complex due to several intervening variables. Rather, the preclinical studies that control for drug dose and regimen, as well as for gestational and postpartum environment, allow a precise determination of the effects of drugs on maternal behaviour. Given the relevance of the issue, this review will gather reports on the phenotypic correlates of maternal behaviour in preclinical stud…
Pharmacokinetics of a sustained release formulation of PDGFβ-receptor directed carrier proteins to target the fibrotic liver
2018
Liver fibrogenesis is associated with excessive production of extracellular matrix by myofibroblasts that often leads to cirrhosis and consequently liver dysfunction and death. Novel protein-based antifibrotic drugs show high specificity and efficacy, but their use in the treatment of fibrosis causes a high burden for patients, since repetitive and long-term parenteral administration is required as most proteins and peptides are rapidly cleared from the circulation. Therefore, we developed biodegradable polymeric microspheres for the sustained release of proteinaceous drugs. We encapsulated the drug carrier pPB-HSA, which specifically binds to the PDGF beta R that is highly upregulated on a…
Plasma phospholipid transfer protein (PLTP) modulates adaptive immune functions through alternation of T helper cell polarization
2016
International audience; Objective: Plasma phospholipid transfer protein (PLTP) is a key determinant of lipoprotein metabolism, and both animal and human studies converge to indicate that PLTP promotes atherogenesis and its thromboembolic complications. Moreover, it has recently been reported that PLTP modulates inflammation and immune responses. Although earlier studies from our group demonstrated that PLTP can modify macrophage activation, the implication of PLTP in the modulation of T-cell-mediated immune responses has never been investigated and was therefore addressed in the present study. Approach and results: In the present study, we demonstrated that PLTP deficiency in mice has a pro…