Search results for "development"
showing 10 items of 26949 documents
Design of New Polyaspartamide Copolymers for siRNA Delivery in Antiasthmatic Therapy
2020
Here, a novel protonable copolymer was realized for the production of polyplexes with a siRNA (inhibitor of STAT6 expression in asthma), with the aim of a pulmonary administration. The polycation was synthesized by derivatization of &alpha
Endocrine disrupters: the new players able to affect the epigenome
2015
Epigenetics represents the way by which the environment is able to program the genome; there are three main levels of epigenetic control on genome: DNA methylation, post-translational histone modification and microRNA expression. The term Epigenetics has been widened by NIH to include “both heritable changes in gene activity and expression but also stable, long-term alterations in the transcriptional potential of a cell that are not necessarily heritable.” These changes might be produced mostly by the early life environment and might affect health influencing the susceptibility to develop diseases, from cancer to mental disorder, during the entire life span. The most studied environmental i…
Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription fa…
2017
Background: Ectomycorrhizal (ECM) fungi develop a mutualistic symbiotic interaction with the roots of their host plants. During this process, they undergo a series of developmental transitions from the running hyphae in the rhizosphere to the coenocytic hyphae forming finger-like structures within the root apoplastic space. These transitions, which involve profound, symbiosis-associated metabolic changes, also entail a substantial transcriptome reprogramming with coordinated waves of differentially expressed genes. To date, little is known about the key transcriptional regulators driving these changes, and the aim of the present study was to delineate and functionally characterize the trans…
Revista Fuentes
2018
La crisis economica sufrida en los ultimos anos, y en concreto en Espana, ha transmitido una cierta desconfianza en la sociedad acerca del valor que posee la educacion para la integracion y promocion socio-laboral de los jovenes, asi como en relacion al impacto que esta tiene para prevenir de la exclusion social a lo largo de la vida. Por desgracia en Espana, aun en la actualidad, que se considera que la crisis economica esta en proceso de superacion, hay una gran cantidad de jovenes que se les identifica como “sobre - formados” y que no encuentran un empleo adecuado a su formacion. Unos acaban trabajando en empleos que requieren menor formacion academica, mientras que otros acaban en el p…
Bordón : revista de pedagogía
2014
Resumen tomado de la publicación. El artículo forma parte de un monográfico titulado : educación supranacional. Se analiza cómo, a partir de los discursos en materia de política educativa establecidos en torno a la literatura de género y a términos como “capacitación de género” y “equidad de género”, así como la consolidación de políticas de mainstreaming (transversalidad de la perspectiva de género) se lleva a reconocer, a través de la Educación Comparada, interesantes hallazgos en este ámbito de estudio e investigación, con un revelador estado de la cuestión supranacional. Desde el enfoque de los sistemas educativos actuales se legitiman, en efecto, las consecuencias de la política global…
External Developmental Assets and Positive Identity Among Emerging Adults in Norway, Romania, Slovenia, and Turkey
2021
The present study adopts The Developmental Assets and Positive Youth Development (PYD) perspectives which (in contrast to the deficit-based approaches which highlight risks and deficit in youth development) claim that young people have potencies to achieve optimal development if supported by their social environment. Extant research indicates that developmental assets are linked with a variety of thriving indicators. The present research aimed to contribute to the PYD research by examining the external developmental assets (support, empowerment, and boundaries and expectations) emerging adults (N= 2055; age range = 18–28) perceived in their social environment and the level of their positive…
Orienting of visuo-spatial attention in developmental dyslexia
2008
POSTNATAL DEVELOPMENTAL CHANGES IN ENTERIC DOPAMINERGIC SYSTEM
2013
The postnatal period is a key period of life, characterized by the maturation of various organs and in particular of the gut. Currently, we have a poor understanding of the development of neurological and endocrine factors that control intestinal motility. Such knowledge can provide indications about the potency, efficacy, or therapeutic range of a drug in premature infants. Dopaminegic antagonists are often used as prokinetic drugs to treat impaired GI propulsion, although the role of the enteric dopaminergic system in the control of intestinal motility in neonatal vs adult has not been adequately addressed. In this view the aim of this study, was to examine, the functionality of the dopam…
Drawnigs as a source of knowledge about the basic developmental needs of children at a younger school age
2018
Potrzeby rozwojowe dzieci w młodszym wieku szkolnym i możliwości ich poznania na podstawie analizy prac rysunkowych
2022
Prawidłowy rozwój dzieci ma związek z realizacją zadań oraz zaspokajaniem potrzeb rozwojowych. Poznanie i zrozumienie tych potrzeb umożliwia rodzicom ich właściwe zaspokajanie. Rysunek będący naturalną formą aktywności dzieci może stanowić źródło wiedzy o ich potrzebach rozwojowych. Artykuł zawiera opis projektu badawczego dotyczącego rysunków dzieci w młodszym wieku szkolnym.