Search results for "developmental"

showing 10 items of 19870 documents

Retroconversion of docosapentaenoic acid (n-6): an alternative pathway for biosynthesis of arachidonic acid in Daphnia magna.

2013

The aim of this study was to assess metabolic pathways for arachidonic acid (20:4n-6) biosynthesis in Daphnia magna. Neonates of D. magna were maintained on [13C] enriched Scenedesmus obliquus and supplemented with liposomes that contained separate treatments of unlabeled docosapentaenoic acid (22:5n-6), 20:4n-6, linoleic acid (18:2n-6) or oleic acid (18:1n-9). Daphnia in the control treatment, without any supplementary fatty acids (FA) containing only trace amounts of 20:4n-6 (~0.3 % of all FA). As expected, the highest proportion of 20:4n-6 (~6.3 %) was detected in Daphnia that received liposomes supplemented with this FA. Higher availability of 18:2n-6 in the diet increased the proportio…

0106 biological sciencesLinoleic acidDaphnia magna01 natural sciencesBiochemistryDaphnia03 medical and health scienceschemistry.chemical_compoundAnimalsreproductive and urinary physiology030304 developmental biologychemistry.chemical_classification0303 health sciencesArachidonic Acidbiology010604 marine biology & hydrobiologyfungiOrganic ChemistryDocosapentaenoic Acid n-6Cell Biologybiology.organism_classificationLipid MetabolismBiosynthetic PathwaysOleic acidBiochemistrychemistryDaphniaLiposomesFatty Acids UnsaturatedArachidonic acidDocosapentaenoic acidHydrogenationPolyunsaturated fatty acidLipids
researchProduct

Immune activation increases susceptibility to oxidative tissue damage in Zebra Finches.

2006

Summary 1The innate immune response involves the production of highly reactive molecules (reactive oxygen and nitrogen species, ROS and RNS). These toxic compounds can effectively destroy invading pathogens but can also, non-specifically, target host cells. Tissue damage caused by ROS and RNS can be substantial if the inflammatory response is overactive, potentially inducing a so-called immunopathology. 2In this study, we induced an inflammatory response in Zebra Finches by the way of a LPS injection (lipopolysaccharide of the cell wall of Escherichia coli), using as a control a group of birds injected with saline (phosphate-buffered saline). Body mass was measured both before and 24 h afte…

0106 biological sciencesLipopolysaccharidefree radicals[ SDV.BBM.BM ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyBiologymedicine.disease_cause010603 evolutionary biology01 natural sciencesimmune activation03 medical and health scienceschemistry.chemical_compoundImmune systemnitric oxideImmunopathologymedicine[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyimmunopathologyZebra finchEcology Evolution Behavior and SystematicsReactive nitrogen speciesComputingMilieux_MISCELLANEOUS030304 developmental biologyZebra Finchchemistry.chemical_classification0303 health sciencesReactive oxygen speciesInnate immune systemlipopolysaccharide[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biology3. Good healthchemistryImmunology[SDV.IMM]Life Sciences [q-bio]/ImmunologyOxidative stress
researchProduct

Male health status, signalled by courtship display, reveals ejaculate quality and hatching success in a lekking species.

2010

8 pages; International audience; Summary 1. The information content of secondary sexual traits and the benefits gathered by choosy females are at the heart of sexual selection theory. Indicator models of sexual selection assume that secondary sexual traits reflect the phenotypic/genetic quality of their bearers and that females gather benefits from choosing these high-quality males. 2. Here, we tested the idea that courtship display reflects the health status in a bird species with a lek-based mating system, the houbara bustard (Chlamydotis undulata undulata). A group of males was treated with the lipopolysaccharide (LPS) of the cell wall of the bacterium Escherichia coli during the seasona…

0106 biological sciencesLipopolysaccharidesMale[ SDV.BDLR.RS ] Life Sciences [q-bio]/Reproductive Biology/Sexual reproductionmedia_common.quotation_subjectHealth StatusZoologyEmbryonic Development[SDV.BID]Life Sciences [q-bio]/BiodiversityBiology010603 evolutionary biology01 natural sciences[SDV.BDLR.RS]Life Sciences [q-bio]/Reproductive Biology/Sexual reproductionCourtshipBirds03 medical and health sciencesSemen qualityLek matingembryo mortalityEscherichia colisexual selectionAnimalsEcology Evolution Behavior and Systematics030304 developmental biologymedia_common[ SDV.BID ] Life Sciences [q-bio]/Biodiversity[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology0303 health sciencesSex CharacteristicsCourtship displayReproductive successEcologyReproductionCourtshipMating systemSpermSpermatozoainflammationSexual selectionFertilizationAnimal Science and ZoologyFemaleGenetic Fitness[SDE.BE]Environmental Sciences/Biodiversity and EcologyThe Journal of animal ecology
researchProduct

Correlational selection on pro- and anti-inflammatory effectors.

2012

9 pages; International audience; Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for host fitness. However, the immune response can also produce self-damage and impair host fitness if not properly regulated. Effectors that up- and downregulate the immune response should, therefore, evolve in concert, and be under the action of correlational selection. To address this issue, we assessed the shape of the selection operating on pro- and anti-inflammatory effectors following an inflammatory challenge in laboratory mice. We found that selection acts on the combination of these two traits as individuals that produced large amount of pro-inflammatory …

0106 biological sciencesLipopolysaccharidesMale[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencesMiceImmunopathologyDarwinian medicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisimmunopathologyGenetics0303 health sciencesEffectorFlow CytometryInterleukin-10Interleukin 10[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyIL-10CytokinesRegression AnalysisFemalemedicine.symptomGeneral Agricultural and Biological Sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitologymedicine.drug_classInflammationBiology010603 evolutionary biologysurvivalAnti-inflammatory03 medical and health sciencesImmune systemImmunityGeneticsmedicineEscherichia coliAnimals[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologySelection GeneticEcology Evolution Behavior and SystematicsSelection (genetic algorithm)030304 developmental biologyIL-6[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologyevolutionary immunologyInterleukin-6inflammationImmunology[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisEvolution; international journal of organic evolution
researchProduct

Anhydrobiosis in Yeasts: Changes in Mitochondrial Membranes Improve the Resistance of Saccharomyces cerevisiae Cells to Dehydration–Rehydration

2019

Anhydrobiosis is a unique state of live organisms in which their metabolism is temporary reversibly suspended as the result of strong dehydration of their cells. This state is widely used currently during large-capacity production of active dry baker&rsquo

0106 biological sciencesLithocholic acidSaccharomyces cerevisiaePlant ScienceMitochondrion01 natural sciencesBiochemistry Genetics and Molecular Biology (miscellaneous)<i>Saccharomyces cerevisiae</i>03 medical and health scienceschemistry.chemical_compound010608 biotechnologymedicinedehydration–rehydrationDehydrationCryptobiosis030304 developmental biologylcsh:TP500-6600303 health sciencesbiologyChemistryMetabolismlcsh:Fermentation industries. Beverages. Alcoholanhydrobiosismedicine.diseasebiology.organism_classificationYeastmitochondriaMembranelithocholic acidBiochemistryFood ScienceFermentation
researchProduct

Can number and size of offspring increase simultaneously?--a central life-history trade-off reconsidered.

2011

Abstract Background To maximize their fitness, parents are assumed to allocate their resources optimally between number and size of offspring. Although this fundamental life-history trade-off has been subject to long standing interest, its genetic basis, especially in wild mammals, still remains unresolved. One important reason for this problem is that a large multigenerational pedigree is required to conduct a reliable analysis of this trade-off. Results We used the REML-animal model to estimate genetic parameters for litter size and individual birth size for a common Palearctic small mammal, the bank vole (Myodes glareolus). Even though a phenotypic trade-off between offspring number and …

0106 biological sciencesLitter (animal)MaleGenetic correlationLitter SizeEvolutionOffspringZoologyTrade-off010603 evolutionary biology01 natural sciencesGenetic correlationHeritability03 medical and health sciencesQuantitative Trait Heritable<it>Myodes glareolus</it>Genetic variationMyodes glareolusQH359-425AnimalsBody SizeSelection GeneticEcology Evolution Behavior and SystematicsSelection (genetic algorithm)030304 developmental biology0303 health sciencesModels StatisticalbiologyArvicolinaeGenetic VariationHeritabilitybiology.organism_classificationBiological EvolutionBirth sizeBank volePhenotypeEvolutionary biologyFemaleResearch ArticleBMC evolutionary biology
researchProduct

Island selection on mammalian life-histories: genetic differentiation in offspring size

2008

Abstract Background Since Darwin's pioneering work, evolutionary changes in isolated island populations of vertebrates have continued to provide the strongest evidence for the theory of natural selection. Besides macro-evolutionary changes, micro-evolutionary changes and the relative importance of natural selection vs. genetic drift are under intense investigation. Our study focuses on the genetic differentiation in morphological and life-history traits in insular populations of a small mammal the bank vole Myodes glareolus. Results Our results do not support the earlier findings for larger adult size or lower reproductive effort in insular populations of small mammals. However, the individ…

0106 biological sciencesLitter (animal)MaleOffspringEvolutionZoology010603 evolutionary biology01 natural sciencesIntraspecific competition03 medical and health sciencesGenetic driftGenetic variationQH359-425AnimalsBirth WeightBody SizeSelection GeneticSelection (genetic algorithm)Ecology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesNatural selectionbiologyGeographyArvicolinaeReproductionBody WeightGenetic Variationbiology.organism_classificationBank voleEvolutionary biologyFemaleResearch Article
researchProduct

Eimeria-parasites are associated with a lowered mother's and offspring's body condition in island and mainland populations of the bank vole.

2006

This study, based on correlative data, tests the hypothesis that infections withEimeriaspp. parasites exert a significant loss of fitness of bank voles (Clethrionomys glareolus) reflected in lower reproductive success and survival, declining host population densities and are associated positively with population size. The study was conducted in 20 mainland and 27 island populations in central Finland during May–September in 1999. Faecal samples showed that 28% of 767 individuals were infected withEimeriaspp. The presence ofEimeriaparasites was higher in dense mainland populations than in sparsely populated islands. Eimerian infections increased during the course of the breeding season, prob…

0106 biological sciencesLitter (animal)MalePopulationZoologyBreeding010603 evolutionary biology01 natural sciencesPopulation densityEimeriaRodent Diseases03 medical and health sciencesFecesCoccidiaPregnancySeasonal breederAnimalseducationFinland030304 developmental biologyPopulation Density0303 health scienceseducation.field_of_studybiologyReproductive successGeographyArvicolinaeCoccidiosisReproductionbiology.organism_classificationSurvival AnalysisBank voleInfectious DiseasesPregnancy Complications ParasiticAnimal Science and ZoologyParasitologyEimeriaFemaleParasitology
researchProduct

Geographical trends in the yolk carotenoid composition of the pied flycatcher (Ficedula hypoleuca).

2010

Carotenoids in the egg yolks of birds are considered to be important antioxidants and immune stimulants during the rapid growth of embryos. Yolk carotenoid composition is strongly affected by the carotenoid composition of the female’s diet at the time of egg formation. Spatial and temporal differences in carotenoid availability may thus be reflected in yolk concentrations. To assess whether yolk carotenoid concentrations or carotenoid profiles show any large-scale geographical trends or differences among habitats, we collected yolk samples from 16 European populations of the pied flycatcher, Ficedula hypoleuca. We found that the concentrations and proportions of lutein and some other xantho…

0106 biological sciencesLuteinRange (biology)Maternal effectsPopulation DynamicsBreedingXanthophylls01 natural sciencesAntioxidantsTreesSongbirdschemistry.chemical_compoundEgg antioxidantspolycyclic compoundsCarotenoidLepidoptera larvaechemistry.chemical_classification0303 health scienceseducation.field_of_studyPrincipal Component AnalysisbiologyGeographyEcologyfood and beveragesbeta CaroteneEgg YolkZeaxanthinEuropeembryonic structuresFemaleTree phenologyfood.ingredientFood ChainPopulation010603 evolutionary biologyInsectivorous birds03 medical and health sciencesfoodYolkAnimalseducationEcology Evolution Behavior and Systematics030304 developmental biologyorganic chemicalsLuteinFicedula15. Life on landbiology.organism_classificationCarotenoidsbiological factorsDietchemistryXanthophyllPhysiological ecology - Original PaperOecologia
researchProduct

Nitric Oxide in Plants: Production and Cross-talk with Ca2+ Signaling

2008

International audience; Nitric oxide (NO) is a diatomic gas that performs crucial functions in a wide array of physiological processes in animals. The past several years have revealed much about its roles in plants. It is well established that NO is synthesized from nitrite by nitrate reductase (NR) and via chemical pathways. There is increasing evidence for the occurrence of an alternative pathway in which NO production is catalysed from L-arginine by a so far non-identified enzyme. Contradictory results have been reported regarding the respective involvement of these enzymes in specific physiological conditions. Although much remains to be proved, we assume that these inconsistencies can …

0106 biological sciencesMAPK/ERK pathwayArabidopsisPlant ScienceCalcium-Transporting ATPasesBiologyNitrate reductaseArginine01 natural sciencesPlant Physiological PhenomenaNitrate ReductaseNitric oxide03 medical and health scienceschemistry.chemical_compoundNitrateProtein kinasesNitrilesAnimals[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyNitriteMolecular BiologyNitritesPlant Physiological Phenomena030304 developmental biologyMammals0303 health sciencesKinasefungiNitric oxidechemistryBiochemistrySecond messenger systemCitrullineCalciumCryptogeinNitric Oxide SynthaseGenome Plant010606 plant biology & botanySignal Transduction
researchProduct