Search results for "difference"

showing 10 items of 1534 documents

What is the influence of parents' myopia on their children's myopic progression? A 22-year follow-up study.

2016

Purpose To study the connection between parental myopia and their children's myopia from school age to adulthood. Methods Two hundred and forty myopic schoolchildren (119 boys, 121 girls, mean age 10.9 years) with no previous spectacles for myopia were recruited to a 3-year treatment trial with different use of spectacles. Follow-ups were performed at mean ages of 13.9, 23.7 and 33.2 years for 238, 176 and 170 subjects respectively. Subjective refraction was calibrated to the spherical equivalent at corneal level (SEcor). Corneal refractive power (CR) and axial length (AL) were measured. Parental myopia was assessed with a questionnaire and the children assigned accordingly to one of three …

0301 basic medicineMaleParentsPediatricsgenetic structuresSpherical equivalentCornea0302 clinical medicineChild of Impaired ParentsSurveys and Questionnairesfollow-upMyopiaYoung adultChildSchool age childFollow up studiesta3142General MedicineAxial lengthcorneal refractionAxial Length EyeEyeglassesDisease ProgressionFemaleAdultmedicine.medical_specialtyAdolescentheredityaxial lengthRefraction Ocular03 medical and health sciencesYoung AdultTreatment trialmedicineHumansGenetic Predisposition to Diseasebusiness.industrySignificant differenceCorneal TopographySubjective refractioneye diseasesta3125Ophthalmology030104 developmental biology030221 ophthalmology & optometryOptometryprogressionsense organsbusinessFollow-Up StudiesActa ophthalmologica
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Long-term effects of a cluster randomized controlled kindergarten-based intervention trial on vegetable intake among Norwegian 3-5-year-olds: the BRA…

2020

AbstractObjectiveTo report on long-term effects of a cluster randomized controlled kindergarten-based intervention trial, which aimed to increase vegetable intake among Norwegian preschool children (3–5 years at baseline). The effects of the intervention at follow-up 1 (immediately post-intervention) have previously been published. This paper presents the effects of the intervention from baseline to follow-up 2 (12 months post-intervention).ResultsParental consents were obtained for 633 out of 1631 eligible children (response rate 38.8%). The effects of the intervention from baseline to follow-up 2 were assessed by mixed-model analyses taking the clustering effect of kindergartens into acco…

0301 basic medicineMaleParentslcsh:MedicineNorwegianDisease clusterGeneral Biochemistry Genetics and Molecular BiologyMean differencelaw.inventionVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciencesEating0302 clinical medicineRandomized controlled triallawSurveys and QuestionnairesVegetablesMedicineHumans030212 general & internal medicineIntervention triallcsh:Science (General)Trial registrationChildlcsh:QH301-705.5Response rate (survey)030109 nutrition & dieteticsSchoolsbusiness.industryNorwaylcsh:RPreschool childrenGeneral MedicineFeeding Behaviorlanguage.human_languageResearch Notelcsh:Biology (General)Child PreschoolFruitlanguageLong-term intervention effectFemaleKindergarten-based interventionbusinessRCTlcsh:Q1-390DemographyFollow-Up StudiesBMC research notes
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Intervention study on school meal habits in Norwegian 10-12-year-old children.

2017

Aim: The aim of this study was to investigate whether a free school meal every day was associated with children’s intake of healthy food during school. Methods: A non-randomized study design with an intervention and a control group was used to measure change in children’s meal habits at lunchtime. In total, 164 children participated; 55 in the intervention group and 109 in the control group. Children in the intervention group were served a free, healthy school meal every school day. Participating children completed a questionnaire at baseline and at 6 months’ follow up. Possible associations were evaluated with a healthy food score, which was calculated based on a food frequency questionna…

0301 basic medicineMalemedicine.medical_specialtyFree school mealIntervention groupNorwegian03 medical and health sciencesIntervention (counseling)MedicineHumansChildSchool Health ServicesMeal030109 nutrition & dieteticsbusiness.industryNorwaydigestive oral and skin physiologySignificant differencePublic Health Environmental and Occupational HealthFood ServicesGeneral MedicineFeeding BehaviorSchool mealIntervention studieslanguage.human_languageLunchlanguagePhysical therapyFemaleDiet HealthybusinessFollow-Up StudiesScandinavian journal of public health
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Effect of rinsing time and surface contamination on the bond strength of silorane-based and dimethacrylate-based composites to enamel

2018

Background The aim of this study was to assess whether saliva contamination and rinsing time for 15, 30, and 60 seconds, affects the shear bond strength of silorane and methacrylate-based composites to enamel. Material and Methods Two light cure resin, P60 (3M ESPE) and Filtek LS Silorane were tested. 120 sound premolars were randomly divided into four groups of 30 teeth based on composite type with or without saliva contamination after etching and rinsing. Each group was further divided into three subgroups according to their rinsing time. Then a cylinder of the composite was bonded to the enamel and Shear bond strength was assessed. To determine the failure mode, the bonded surfaces were …

0301 basic medicineMaterials scienceEnamel paintBond strengthResearchComposite number030206 dentistryContaminationMethacrylate:CIENCIAS MÉDICAS [UNESCO]Operative Dentistry and Endodontics03 medical and health sciences030104 developmental biology0302 clinical medicineLeast significant differencestomatognathic systemvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumShear strengthAdhesiveComposite materialGeneral Dentistry
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Large area conductive nanoaperture arrays with strong optical resonances and spectrally flat terahertz transmission

2017

Using simple and inexpensive nanosphere lithography, we produce large, centimeter-squared sized thin golden films patterned with a hexagonal array of nanoapertures with controllable dimensions on the order of 100–300 nm, spaced by a 350–375 nm pitch distance. The optical transmission spectra of our samples are dominated by the resonant plasmonic features in the spectral range 500–700 nm, caused by the nanostructure in the film. At the same time, the transmission at terahertz (THz) radiation is as high as ∼10% and is spectrally flat. Our measurements are in agreement with finite difference time domain simulations. Such thin metal hole array films allow for very efficient injection of optical…

0301 basic medicineNanostructureMaterials sciencePhysics and Astronomy (miscellaneous)Terahertz radiationbusiness.industryNanophotonicsFinite-difference time-domain methodPhysics::Optics02 engineering and technologyPhysik (inkl. Astronomie)021001 nanoscience & nanotechnology03 medical and health sciences030104 developmental biologyNanolithographyOpticsTransmission (telecommunications)OptoelectronicsNanosphere lithography0210 nano-technologybusinessPlasmonApplied Physics Letters
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Gender medicine and oncology: report and consensus of an ESMO workshop.

2019

Background: The importance of sex and gender as modulators of disease biology and treatment outcomes is well known in other disciplines of medicine, such as cardiology, but remains an undervalued issue in oncology. Considering the increasing evidence for their relevance, European Society for Medical Oncology decided to address this topic and organized a multidisciplinary workshop in Lausanne, Switzerland, on 30 November and 1 December 2018.

0301 basic medicineOncologyMalemedicine.medical_specialtypopulation pharmacokinetic analysissuperior survivalDecision MakingMEDLINElymphomaDiseaseclearanceMedical Oncology03 medical and health sciences0302 clinical medicinerituximabInternal medicineNeoplasmsPhysiciansEpidemiologymedicinegendermelanomasexcancerHumansDosingfemale-patientsSex Characteristicsbusiness.industrygender medicineCancerHematologymedicine.diseaseChemotherapy regimenClinical trial030104 developmental biologyTreatment Outcome030220 oncology & carcinogenesisoncologyimpactBody CompositionFemalepharmacologybusinesssex-differencesSex characteristicsAnnals of oncology : official journal of the European Society for Medical Oncology
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Denosumab for bone health in prostate and breast cancer patients receiving endocrine therapy? A systematic review and a meta-analysis of randomized t…

2019

Highlights • Hormonal receptors positive breast tumor and prostate cancer are managed with endocrine therapies. • Endocrine therapies designed for breast and prostate cancer are often associated to serious adverse skeletal related events, such fractures. • Denosumab is a monoclonal anti-body binding RANKL which acts as inhibitor of osteoclasts activity, thus increasing bone mass. • Denosumab was showed to strongly prevent hormonal therapies-related skeletal issues. • Denosumab administration results safe in bone mass increase and reduction of fractures risk.

0301 basic medicineOncologyRCTs randomized clinical trialrandomized clinical trialslcsh:Diseases of the musculoskeletal systemSettore MED/06 - Oncologia MedicaOsteoporosisBMD bone mass densityReview Articleandrogen deprivation therapyADTlaw.inventionAndrogen deprivation therapyProstate cancerhazard ratio0302 clinical medicineRandomized controlled triallawHRMedicineBreastSAEsCancerProstateRANKLCIMD mean differencelcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensRCTs randomized clinical trialsDenosumabOncology030220 oncology & carcinogenesisSAEs serious adverse eventsDenosumabmean differencemedicine.drugmedicine.medical_specialtylcsh:RC254-28203 medical and health sciencesBreast cancerRANKL receptor activator of nuclear factor-kB ligandBMDInternal medicineAdverse effectADT androgen deprivation therapyRCTsbusiness.industryMDmedicine.diseaseHR hazard ratioHormonereceptor activator of nuclear factor-kB ligandDiscontinuationCI confidence interval030104 developmental biologyFractureconfidence intervalADT androgen deprivation therapy; BMD bone mass density; Breast; CI confidence interval; Cancer; Denosumab; Fracture; HR hazard ratio; Hormone; MD mean difference; Prostate; RANKL receptor activator of nuclear factor-kB ligand; RCTs randomized clinical trials; SAEs serious adverse eventsserious adverse eventsbone mass densitylcsh:RC925-935businessJournal of Bone Oncology
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Lymphocytes as a Biomarker of Frailty Syndrome: A Scoping Review

2021

Frailty is a geriatric syndrome characterized by a decrease in physiological reserve and reduced resistance to stress, as a result of an accumulation of multiple deficits in physiological systems. Frailty increases the vulnerability to adverse events and is associated with the aging process. Several studies show an association between frailty syndrome and altered blood lymphocyte levels, which is therefore potentially useful for monitoring interventions to improve or delay frailty. The main objective of this review is to provide an analysis of the current evidence related to changes in lymphocyte counts and their associations with frailty syndrome. To that end, the literature published in t…

0301 basic medicineOncologymedicine.medical_specialtyLymphocyteFrailty syndromeReview03 medical and health sciences0302 clinical medicineInternal medicineCD4 cellsMedicineAdverse effectgeriatric evaluationbusiness.industryCD8-cellsRbiomarkersmedicine.diseaseimmunityBlood lymphocyte030104 developmental biologymedicine.anatomical_structuregender differences030220 oncology & carcinogenesisBiomarker (medicine)MedicinebusinessDiseases
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Detection of mast cells in ameloblastomas and odontogenic keratocysts

2020

Background MCs (MCs) have been ascribed to mediating several diseases, including malignant neoplasms. These cells can play a role in angiogenesis, tissue remodeling and immune modulation and favor neoplasm progression. Despite the studies analyzing the contribution of MCs in odontogenic lesions, its biological behavior in ameloblastomas (AMBs) and odontogenic keratocysts (OKCs) remains unclear. This study aims to detect MCs in OKCs and AMBs and clarify the role of MCs in these lesions. Material and methods A total of 40 odontogenic lesions were analyzed. This included 20 OKCs and 20 AMBs, 10 being the solid type and the other 10 being the unicystic type of AMB. All cases were histologically…

0301 basic medicinePathologymedicine.medical_specialtyOral Medicine and Pathology030102 biochemistry & molecular biologybusiness.industryResearchanimal diseasesSignificant differenceImmune modulation:CIENCIAS MÉDICAS [UNESCO]humanitiesOdontogenic03 medical and health sciencesNeoplasm progression0302 clinical medicineTissue remodeling030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASMedicinebusinessGeneral Dentistry
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Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data

2017

BACKGROUND Macrophages and plasma cells play a key role in the regulation of innate and adaptive immunity. The aim of this study was to assess the presence of these cells in apical periodontitis and their distribution comparing with clinical and image data. MATERIAL AND METHODS Thirty-three lesions were selected and divided in two groups (17 periapical cysts and 16 periapical granulomas). Immunoreactions using anti-CD68 and anti-CD138 antibodies were carried out; image analysis was performed with an optical microscope and 5 high-power fields from each slide were evaluated leading to an average score of immunoexpression. This mean score was compared between the two groups and correlated with…

0301 basic medicinePathologymedicine.medical_specialtyPeriapical cystPeriapical GranulomaOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicineMedicineDistribution (pharmacology)General DentistryPeriodontitisbiologybusiness.industryCD68ResearchSignificant difference030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseAcquired immune system030104 developmental biologyUNESCO::CIENCIAS MÉDICASbiology.proteinAntibodybusinessJournal of Clinical and Experimental Dentistry
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