Search results for "differentiated"
showing 10 items of 67 documents
Cytochemical Cell Typing of Metastatic Tumors According to their Cytoskeletal Proteins
1986
Conventional staining methods alone are often insufficient to make accurate histodiagnosis of malignant tumors. However, additional information about the cell type and the state of differentiation of tumor cells can be provided by several molecular markers. To be relevant diagnostically, these markers must be conservative, i.e. expressed not only in well differentiated tumors but also in poorly differentiated tumors and in metastases. These criteria are fulfilled by certain components of the cytoskeleton, notably the proteins forming the intermediate-sized filaments (IFs) and the desmosomal plaque proteins.
Endpoint Admission Control over Assured Forwarding PHBs and Its Performance over RED Implementations
2001
The Assured Forwarding Per Hop Behavior (AF PHB) has been devised by the IETF Differentiated Services (DiffServ) working group to provide drop level differentiation. The intent of AF is to support services with different loss requirements, but with no strict delay and jitter guarantees. Another suggested use of AF is to provide differentiated support for traffic conforming to an edge conditioning/policing scheme with respect to nonconforming traffic. Scope of this paper is twofold. First, we show that, quite surprisingly, a standard AF PHB class is semantically capable of supporting per flow admission control. This is obtained by adopting the AF PHB as core routers forwarding mechanism in c…
PCP: An End-to end Measurement Based Call Admission Control for Real-Time Services Over IP Networks
2000
Distributed end-to-end measurement based connection admission control mechanisms have been recently proposed. The goal of these schemes is to provide tight QoScon trol on a per connection basis by means of measurements taken by the edge nodes and priority based forwarding procedure at internal nodes. Since the additional flows handling procedures are implemented at the border routers and the forwarding mechanisms are for flows aggregates only, the approach is fully scalable and compatible with the IETF Differentiated Service proposal. The aim of this paper is to propose specific schemes and to investigate the advantages and limits of the approach by analyzing the basic mechanisms and evalua…
The meanings of differentiated instruction in the narratives of Eritrean teachers
2021
The principles of inclusive education largely accepted by governments of different countries require differentiated classroom instruction to meet the diverse needs of individual students. Despite this, teachers have differing experiences and understandings about implementing differentiated instruction (DI) and heterogeneous classrooms. This narrative study aimed at exploring the meanings of DI in the Eritrean context, where teachers are not explicitly familiar with the concept, although their teaching practices reflect some level of differentiation. The research data consisted of 17 narrative interviews with Eritrean mathematics and science teachers. The results of the narrative analysis sh…
Vergleich der DNS-Analyse mit histomorphologischen parametern beim Magenkarzinom
1992
After curative resection of stomach carcinomas (adenocarcinomas: n=58, signet ring cell carcinomas: n = 24, undifferentiated carcinomas: n = 21) the DNA content of the tumor cells was compared with the histomorphological parameters. There was a correlation between the DNA content and the histomorphological parameters. The DNA analysis had no additionally prognostic influence. In the multivariate regression analysis the prognosis depended on lymph node status (p=0.0009), pT-stage (p = 0.02), tumor localization (p = 0.03) and the histological type (p=0.05). The prognosis was independent of the DNA content. Furthermore, neither did the degree of differentiation, the operative procedure, the sa…
Ziel- und leistungsdifferenziertes Lernen und Arbeiten
2020
An increasing variety of language (learning) biographies characterize a differentiation of goals and achievements in foreign language teaching. At the same time, they have to comply with curricula and assessment standards. The paper points out and reflects possible steps and teaching methods that could be used.
Per-flow signalling extension across DiffServ domains
2003
This paper describes a framework devised to extend per-flow admission control operation across Differentiated Services domains. Although the specific case of interoperability with RSVP is under discussion, our proposal can be easily adapted to other hop-by-hop signalling protocols. In our framework, DiffSery border routers accomplish three tasks. First, during the set-up phase, flows are mapped onto PHB groups on the basis of their QoS and traffic specifications. Second, signalling packets are tunnelled into IP packets marked as “probes”, where the “probe” marking is a DCSP value associated to the considered PHB Group. Third, when the flow set-up is complete, flow data packets are marked as…
Exploring Differentiated Disintegration in a Post-Brexit European Union
2019
In the aftermath of the British referendum to leave the European Union and the European Commission's ‘White Paper on the Future of Europe’, it is not only time to take stock of the existing literature on differentiated integration, but also to rethink the perimeters of disintegration. We argue that phenomena such as Brexit embrace forms of differentiation which trigger the need for conceptualizing differentiated disintegration altogether. This article first sketches the path of the scholarly debate in a chronological way to grasp the breadth of existing literature. Second, it discusses differentiated disintegration as a potentially new area for research. Mapping several scenarios for future…
Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma.
2019
During wound repair, branching morphogenesis and carcinoma dissemination, cellular rearrangements are fostered by a solid-to-liquid transition, known as unjamming. The biomolecular machinery behind unjamming and its pathophysiological relevance remain, however, unclear. Here, we study unjamming in a variety of normal and tumorigenic epithelial two-dimensional (2D) and 3D collectives. Biologically, the increased level of the small GTPase RAB5A sparks unjamming by promoting non-clathrin-dependent internalization of epidermal growth factor receptor that leads to hyperactivation of the kinase ERK1/2 and phosphorylation of the actin nucleator WAVE2. This cascade triggers collective motility effe…
Adding Real-Time Networking and QoS Capabilities to RTLinux-GPL
2006
This paper presents an architecture to build distributed embedded real-time systems in the RTLinux-GPL platform. The architecture (built in a layered fashion) has being built around open source projects ranging from Ethernet drivers to a CORBA environment. The paper focuses on those layers that give support for QoS and real-time networking over Ethernet networks. The main ideas are: to accomplish deterministic access times by using a TDMA protocol over Ethernet and to multiplex different types of traffic in that real-time network, providing different service types (QoS) to each type of traffic without jeopardizing the a priori guarantee of the system's real-time properties. Traffic types in…