6533b86dfe1ef96bd12c9e04

RESEARCH PRODUCT

Vergleich der DNS-Analyse mit histomorphologischen parametern beim Magenkarzinom

Helmut E. GabbertAchim HeintzTh. JungingerH. MenkeMichael StöckleTh. BöttgerS. WellekH. C. JauckusA. Grenz

subject

Curative resectionPathologymedicine.medical_specialtyHistological typeSignet ring cellbusiness.industryStomachTumor cellsmedicine.anatomical_structureSTOMACH CARCINOMAmedicineSurgeryUndifferentiated carcinomabusinessLymph node

description

After curative resection of stomach carcinomas (adenocarcinomas: n=58, signet ring cell carcinomas: n = 24, undifferentiated carcinomas: n = 21) the DNA content of the tumor cells was compared with the histomorphological parameters. There was a correlation between the DNA content and the histomorphological parameters. The DNA analysis had no additionally prognostic influence. In the multivariate regression analysis the prognosis depended on lymph node status (p=0.0009), pT-stage (p = 0.02), tumor localization (p = 0.03) and the histological type (p=0.05). The prognosis was independent of the DNA content. Furthermore, neither did the degree of differentiation, the operative procedure, the safety distance, the size of the tumor, the sex nor the age of the patient have any influence on the prognosis.

yearjournalcountryeditionlanguage
1992-01-01Langenbecks Archiv fur Chirurgie
https://doi.org/10.1007/bf00186141