Search results for "differentiation"

Līdzatkarības, pašdiferencācijas un personības iezīmju savstarpējā saistība sievietēm

2019

Šī pētījuma mērķis bija noskaidrot, vai pastāv savstarpēja saistība starp līdzatkarību, pašdiferencāciju un personības iezīmēm sievietēm. Pētījumā piedalījās 113 sievietes (N = 113), vecumā no 20 līdz 30 gadiem (M = 24,5, SD = 3,23), kuras ir vismaz 1 gadu ilgās romantiskās attiecībās. Respondenti aizpildīja trīs aptaujas: Līdzatkarības noteikšanas aptauju, Lielā Piecinieka Aptauju (BFI) un Pašdiferencācijas aptauju - Īso versiju (DSI-SF), kura tika adaptēta latviešu valodā bakalaura darba ietvaros. Pētījuma rezultāti parāda: statistiski nozīmīgu negatīvu korelāciju starp līdzatkarību un pašdiferencāciju; statistiski nozīmīgu negatīvu saistību starp līdzatkarību un atvērtību pieredzei, apzi…

Effect of Enculturation on the Semantic and Acoustic Correlates of Polyphonic Timbre

2011

polyphonic timbre perception was investigated in a cross-cultural context wherein Indian and Western nonmusicians rated short Indian and Western popular music excerpts (1.5 s, n = 200) on eight bipolar scales. Intrinsic dimensionality estimation revealed a higher number of perceptual dimensions in the timbre space for music from one's own culture. Factor analyses of Indian and Western participants' ratings resulted in highly similar factor solutions. The acoustic features that predicted the perceptual dimensions were similar across the two participant groups. Furthermore, both the perceptual dimensions and their acoustic correlates matched closely with the results of a previous study perfor…

Mitochondrial sequence analysis of Salamandra taxa suggests old splits of major lineages and postglacial recolonizations of Central Europe from disti…

2000

Representatives of the genus Salamandra occur in Europe, Northern Africa and the Near East. Many local variants are known but species and subspecies status of these is still a matter of dispute. We have analysed samples from locations covering the whole expansion range of Salamandra by sequence analysis of mitochondrial D-loop regions. In addition, we have calibrated the rate of divergence of the D-loop on the basis of geologically dated splits of the closely related genus Euproctus. Phylogenetic analysis of the sequences suggests that six major monophyletic groups exist (S. salamandra, S. algira, S. infraimmaculata, S. corsica, S. atra and S. lanzai) which have split between 5 and 13 milli…

Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth

2010

Nerve Growth Factor (NGF)-induced neuronal differentiation requires the activation of members of the Rho family of small GTPases. However, the molecular mechanisms through which NGF regulates cytoskeletal changes and neurite outgrowth are not totally understood. In this work, we identify the Rac1-specific guanine exchange factor (GEF) Tiam1 as a novel mediator of NGF/TrkA-dependent neurite elongation. In particular, we report that knockdown of Tiam1 causes a significant reduction in Rac1 activity and neurite outgrowth induced by NGF. Physical interaction between Tiam1 and active Ras (Ras- GTP), but not tyrosine phosphorylation of Tiam1, plays a central role in Rac1 activation by NGF. In add…

Специфика перевода и лексикографического описания эортологической лексики

2022

Religious vocabulary covers a very wide area and includes numerous thematic blocks. From the lexicographer's point of view, it can be divided into two groups. The first is popular words often used in everyday life, and the second group in this conditional classification covers terminological religious vocabulary of a thematic nature, ranging from purely material, subject, cult concepts, and ending with philosophical and theological concepts. In the context of ongoing research, the author is interested in the specifics of translation and lexicographic description of eortonyms.

Low levels of both xanthine dehydrogenase and of cellular retinol binding protein are responsible for retinoic acid deficiency in malignant human mam…

2009

The seeming impairment of retinoid metabolism in human breast tumor cells has been attributed to the lower expression of cellular retinol binding proteins (CRBPs), of alcohol/retinol dehydrogenases, or aldehyde/retinaldehyde dehydrogenases. In a previous study we indicated that xanthine dehydrogenase (XDH) is able to oxidize actively both all-trans-retinol (t-ROL) bound to the CRBP (holo-CRBP) and all-trans-retinaldehyde (t-RAL) to all-trans-retinoic acid (t-RA) in human mammary epithelial cells (HMEC). Since both XDH and CRBP are required for the biosynthesis of t-RA, we have inspected their bioavailability in both estrogen-responsive and nonresponsive human mammary epithelial cancer cells…

Photoluminescent Detection of Human T-Lymphoblastic Cells by ZnO Nanorods.

2020

The precise detection of cancer cells currently remains a global challenge. One-dimensional (1D) semiconductor nanostructures (e.g., ZnO nanorods) have attracted attention due to their potential use in cancer biosensors. In the current study, it was demonstrated that the possibility of a photoluminescent detection of human leukemic T-cells by using a zinc oxide nanorods (ZnO NRs) platform. Monoclonal antibodies (MABs) anti-CD5 against a cluster of differentiation (CD) proteins on the pathologic cell surface have been used as a bioselective layer on the ZnO surface. The optimal concentration of the protein anti-CD5 to form an effective bioselective layer on the ZnO NRs surface was selected. …

The Assessment of Self-Other Differentiation: A Contribution to the Italian Validation of the “Self-Other Differentiation Scale”.

2018

Skin Immunomodulation during Regeneration: Emerging New Targets

2021

Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation activities. They orchestrate, through their exosome, the mechanisms associated to cell differentiation, proliferation, and cell migration by upregulating genes implicated in different functions including skin barrier, immunomodulation, cell proliferation, and epidermal regeneration. ADSCs directly interact with their microenvironment and specifically the immune cells, including macrophages and T and B cells, resulting in differential inflammatory and anti-inflammatory mechanisms impacting, in return, ADSCs microenvironment and …

Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing

2020

Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal sheets (dermal sheet cells), in interfollicular dermis, and in the hypodermis tissue. These cells are expected to play a major role in regulating skin regeneration and aging-associated morphologic disgraces and structural deficits. ADSCs are known to proliferate and differentiate into skin cells to repair damaged or dead cells, but also act by an autocrine and paracrine pathway to activate cell regeneration and the healing process. During wound healing, ADSCs have a great ability in migration to be recruited rapidly…