Search results for "don"

showing 10 items of 8430 documents

Impact of combinatory growth factor application on rabbit Achilles tendon injury with operative versus conservative treatment: A pilot study

2009

Acute Achilles tendon (AT) rupture is a common injury with a comparatively high complication rate. Presently, surgical treatments compete with nonoperative treatment modalities. The aim of this study was to elucidate the possible beneficial effects of short-term combinatory application of growth factors on tendon healing during operative or conservative treatment. In this controlled laboratory study, the left ATs of 40 adult New Zealand White rabbits were transected and either sutured or treated conservatively. Half of the animals from each treatment modality group repetitively received a mixture of VEGF165, bFGF, and rPDGF which was administered peritendineally. The left legs were immobili…

Achilles tendonmedicine.medical_specialtybusiness.industryGrowth factormedicine.medical_treatmentGeneral MedicineSurgeryNonoperative treatmentConservative treatmentmedicine.anatomical_structureAchilles tendon injuryGeneticsmedicineMarginal impactbusinessTendon healingBlood vesselInternational Journal of Molecular Medicine
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Structure and function of human triceps surae muscle and tendon in aging

2016

Achilles tendonstiffnessikääntyminenmuscle architecturepohjelihasagingjäykkyystriceps suraepohkeetlihaksetkantajännebiomekaniikka
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Acid-mediated reaction of bis(pyridine)iodonium(I) tetrafluoroborate with aromatic compounds. A selective and general iodination method

1993

Reaction of aromatic compounds with bis(pyridine)iodonium(I) tetrafluoroborate (IPy2BF4) in the presence of HBF4 or CF3SO3H in CH2Cl2 at room temperature furnishes monoiodo derivatives with excellent regioselectivity and yields. Use of either acid gives comparable results with activated aromatics, whereas CF3SO3H is much more effective in the iodination of deactivated aromatics. © 1993 American Chemical Society.

Acid catalysischemistry.chemical_compoundElectrophilic substitutionTetrafluoroboratechemistryOrganic ChemistryPyridineRegioselectivityHalogenationOrganic chemistryBis(pyridine)iodonium(I) tetrafluoroborateChemical societyThe Journal of Organic Chemistry
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Dissemination of a Carbapenem-Resistant Acinetobacter baumannii Strain Belonging to International Clone II/Sequence Type 2 and Harboring a Novel AbaR…

2013

ABSTRACT An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a bla OXA-23 -positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacE Δ 1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ∼46,500 bp containing structures similar to the previously described AbaR22 and Tn 6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn 6022a interrupted by Tn 2006 carrying the bla OXA-23 gene.

Acinetobacter baumanniiclone (Java method)Genomic IslandsMolecular Sequence DataMicrobial Sensitivity TestsIntegronbeta-Lactam Resistancebeta-LactamasesDisease OutbreaksIntegronsMicrobiologyMechanisms of ResistancePharmacology (medical)GeneVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical molecular biology: 711Sequence (medicine)PharmacologyCross InfectionMolecular EpidemiologyMolecular epidemiologyStrain (chemistry)biologyOutbreakMethyltransferasesVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical microbiology: 715biology.organism_classificationLatviaAnti-Bacterial AgentsBacterial Typing TechniquesAcinetobacter baumanniiInfectious DiseasesCarbapenemsVDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk immunologi: 716VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk mikrobiologi: 715DNA Transposable Elementsbiology.proteinGenes MDRVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical immunology: 716VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk molekylærbiologi: 711Acinetobacter Infections
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Efficacy of an amine fluoride-triclosan mouthrinse as compared to the individual active ingredients

2003

Background: The purpose of the clinical study was to examine the antibacterial and plaque-reducing properties of mouthrinses containing triclosan (TRI), amine fluoride (AmF), and the combination of both (AFT) on 4-day plaque regrowth. A placebo solution (PLA) and a 0.2% chlorhexidine solution (CHX) served as negative and positive controls, respectively. Materials & Methods: After a professional tooth cleaning (day 0), 15 volunteers refrained from all mechanical oral hygiene measures for the next 96 h and rinsed instead twice daily for 1 min with 10 ml of one of the five randomly assigned solutions. Plaque index (PlI), which was assessed after 24 and 96 h (PlI1, PlI2), and plaque area of the…

Active ingredientbusiness.industryChemistryChlorhexidineAmine fluorideBiofilmDentistryPlaceboOral hygieneTriclosanchemistry.chemical_compoundStatistical significancemedicinePeriodonticsbusinessmedicine.drugJournal of Clinical Periodontology
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Older people’s participation in political organizations: The role of generativity and its impact on well-being

2017

Aging population has increased a global concern to keep seniors active and healthy. Civic participation, in particular, has been highlighted for its social and community benefits and its impact on elders’ health and well-being. To date, however, most studies have explored volunteering; other types of civic activities, such as political participation, are largely overlooked. This study analyzes the relationship between older people’s active involvement in political organizations, generativity, and hedonic and eudaimonic well-being. We selected two samples of Spanish older people: a sample of elders actively involved in political organizations (n = 97) and a comparison group (n = 85). Measure…

Active involvementPopulation050109 social psychologySample (statistics)EudaimoniaEducationCIENCIAS SOCIALES03 medical and health sciencesPolitics030502 gerontology0501 psychology and cognitive scienceseducationeducation.field_of_studyGenerativityhedonic wellbeing05 social scienceseudaimonic wellbeingPsicologíahumanitiesgenerativityWell-beingGeriatrics and Gerontology0305 other medical scienceOlder peoplePsychologypolitical participationSocial psychologyEducational Gerontology
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Prognosis Impact of Diabetes in Elderly Women and Men with Non-ST Elevation Acute Coronary Syndrome

2021

Few studies have addressed to date the interaction between sex and diabetes mellitus (DM) in the prognosis of elderly patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). Our aim was to address the role of DM in the prognosis of non-selected elderly patients with NSTEACS according to sex. A retrospective analysis from 11 Spanish NSTEACS registries was conducted, including patients aged ≥70 years. The primary end point was one-year all-cause mortality. A total of 7211 patients were included, 2,770 (38.4%) were women, and 39.9% had DM. Compared with the men, the women were older (79.95 ± 5.75 vs. 78.45 ± 5.43 years, p &lt

Acute coronary syndromemedicine.medical_specialtyAnemiaMujermedicine.medical_treatment:enfermedades nutricionales y metabólicas::enfermedades metabólicas::trastornos del metabolismo de la glucosa::diabetes mellitus [ENFERMEDADES]Enfermedad cardiovascularAnciano:Otros calificadores::/diagnóstico [Otros calificadores]DonesDietética y nutriciónDiseaseMalalties coronàriesRevascularizationelderlyArticleCoronary diseasesInfarto del miocardio sin elevación del STnon-ST-segment elevation acute coronary syndromesDiabetes mellitusInternal medicine:Other subheadings::/diagnosis [Other subheadings]medicineClinical endpointEndocrinologíaWomen:Diagnosis::Prognosis [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Diabetis - Prognosi:diagnóstico::pronóstico [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]Diabetisbusiness.industryST elevationDiabetesRGeneral Medicinemedicine.disease:Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus [DISEASES]Diabetes mellitus tipo 2diabetes mellitusDiferències entre sexes:enfermedades cardiovasculares::enfermedades cardíacas::isquemia miocárdica::síndrome coronario agudo [ENFERMEDADES]Medicinewomenbusiness:Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Acute Coronary Syndrome [DISEASES]Kidney disease
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Towards More Specificity and Effectivity in the Antileukemia Immune Response

2014

Experimental and clinical studies have shown that alloreactive T-cell responses derived from donor lymphocytes can effectively eliminate leukemia cells after allogeneic hematopoietic stem cell transplantation. However, there are still too many patients in whom this graft-versus-leukemia reactivity is insufficient to prevent leukemia relapse or who suffer from severe alloreactivity to nonmalignant host tissues also mediated by donor-derived T cells. Therefore, various conceptually different approaches have been developed at the level of donor T cells in order to improve the efficacy of leukemia-directed immunity while reducing the incidence of unwanted graft-versus-host disease. As outlined …

Acute promyelocytic leukemiabusiness.industrymedicine.medical_treatmentMyeloid leukemiaHematopoietic stem cell transplantationmedicine.diseaseDonor LymphocytesMinimal residual diseaseTransplantationLeukemiaImmune systemImmunologyMedicinebusiness
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Adenoma Pleomorfo de Glándula Lagrimal: Presentación de un caso clínico

2005

Los tumores de la glándula lagrimal son raros. Se presenta el caso clínico de un paciente masculino de 69 años de edad que consulta por un tumor (Adenoma Pleomorfo) en la región orbitaria derecha, de un año de evolución. Se realizó la escisión quirúrgica del mismo y la recuperación del paciente fue muy satisfactoria, sin recidivas tras un año de seguimiento. Se realiza también una revisión de las características clínicas, radiográficas e histopatológicas de estos tumores. Lacrimal gland tumors are rare. We present a case of a 69 year old male patient with a one year history of an orbital tumor (Pleomorphic Adenoma ). The tumor was surgically enucleated and patient recovery was very satisfac…

Adenoma pleomorfoUNESCO::CIENCIAS MÉDICASglándula lagrimaltumor mixto benignoOdontología:CIENCIAS MÉDICAS [UNESCO]Ciencias de la salud
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Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

1999

Hereditary papillary renal carcinoma (HPRC) is characterized by multiple, bilateral papillary renal carcinomas. Previously, we demonstrated missense mutations in the tyrosine kinase domain of the MET proto-oncogene in HPRC and a subset of sporadic papillary renal carcinomas. In this study, we screened a large panel of sporadic papillary renal carcinomas and various solid tumors for mutations in the MET proto-oncogene. Summarizing these and previous results, mutations of the MET proto-oncogene were detected in 17/129 sporadic papillary renal carcinomas but not in other solid tumors. We detected five novel missense mutations; three of five mutations were located in the ATP-binding region of t…

AdenomaModels MolecularCancer ResearchProtein ConformationDNA Mutational AnalysisMolecular Sequence DataHereditary Papillary Renal Cell CarcinomaBiologymedicine.disease_causeTransfectionProto-Oncogene MasReceptor tyrosine kinaseMiceAdenosine TriphosphateNeoplastic Syndromes HereditaryProto-OncogenesGeneticsCarcinomamedicineMissense mutationAnimalsHumansPoint MutationAmino Acid SequencePhosphorylationCodonMolecular BiologyKidneyMutationBinding SitesSequence Homology Amino AcidPoint mutation3T3 CellsDNA NeoplasmProto-Oncogene Proteins c-metmedicine.diseaseCarcinoma PapillaryKidney NeoplasmsNeoplasm Proteinsmedicine.anatomical_structureCell Transformation NeoplasticCancer researchbiology.proteinMutagenesis Site-DirectedTyrosine kinaseProtein Processing Post-TranslationalSequence AlignmentOncogene
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