Search results for "elements"

showing 10 items of 799 documents

Polymorphism of immunoglobulin enhancer element HS1,2A: allele *2 associates with systemic sclerosis. Comparison with HLA‐DR and DQ allele frequency

2007

OBJECTIVE: To investigate the relationship of the polymorphic enhancer HS1,2 central to the 3' enhancer complex regulatory region (IgH3'EC) of the immunoglobulin heavy chain genes with systemic sclerosis (SSc) disease and compare it with HLA-DR and DQ associations. METHODS: A total of 116 patients with SSc were classified as diffuse (dSSc) or limited (lSSc), and as carriers of antitopoisomerase I (anti-Scl70) or anticentromere (ACA) antibodies. Allele and genotype frequencies were assessed in the population as a whole and in the two major subsets, dSSc and lSSc. The concentration of peripheral blood immunoglobulin levels was also determined and analysed according to the genotypes. RESULTS: …

MaleSettore MED/16 - REUMATOLOGIAsystemic sclerosisclinical evaluationgenotype phenotype correlationHLA DR antigenSclerodermaGene FrequencyGenotypeImmunology and Allergycentromere antibody; HLA DR antigen; immunoglobulin enhancer binding protein; scl 70 antibody; adult; aged; article; clinical evaluation; controlled study; DNA polymorphism; female; gene frequency; genotype phenotype correlation; human; major clinical study; male; priority journal; risk factor; systemic sclerosis; Adult; Aged; Autoantibodies; Enhancer Elements (Genetics); Esophagus; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; HLA-DQ Antigens; HLA-DR Antigens; Humans; Immunoglobulin Heavy Chains; Male; Middle Aged; Phenotype; Polymorphism Genetic; Scleroderma Systemic; Statistics Nonparametric; Stomacheducation.field_of_studycentromere antibodyStatisticsStomacharticleMiddle AgedExtended Reportimmunoglobulin enhancer binding proteinEnhancer Elements GeneticPhenotypepriority journalrisk factorFemaleImmunoglobulin Heavy ChainsAdultGenotypeImmunologyPopulationBiologyGeneral Biochemistry Genetics and Molecular BiologyStatistics NonparametricEsophagusGeneticRheumatologyHLA-DQ AntigensHLA-DRHumanscontrolled studyEnhancer Elements (Genetics)NonparametricGenetic Predisposition to DiseasehumanPolymorphismAlleleeducationEnhancerAllele frequencyAgedAutoantibodiesscl 70 antibodyPolymorphism GeneticScleroderma SystemicSystemicHLA-DR Antigensmajor clinical studyGenotype frequencySettore BIO/18 - GeneticaDNA polymorphismImmunologyImmunoglobulin heavy chain
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Spin up and phase fluctuations in the timing of the accreting millisecond pulsar XTE J1807-294

2007

We performed a timing analysis of the 2003 outburst of the accreting X-ray millisecond pulsar XTE J1807-294 observed by RXTE. Using recently refined orbital parameters we report for the first time a precise estimate of the spin frequency and of the spin frequency derivative. The phase delays of the pulse profile show a strong erratic behavior superposed to what appears as a global spin-up trend. The erratic behavior of the pulse phases is strongly related to rapid variations of the light curve, making it very difficult to fit these phase delays with a simple law. As in previous cases, we have therefore analyzed separately the phase delays of the first harmonic and of the second harmonic of …

Orbital elementsPhysicsAstrophysics::High Energy Astrophysical PhenomenaAstrophysics (astro-ph)Phase (waves)Static timing analysisFOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsLight curveAstrophysicsPulsars: General Stars: Pulsars: Individual: Alphanumeric: XTE J1807-294 Stars: Magnetic Fields Stars: Neutron X-Rays: Binaries [Stars]Pulse (physics)Settore FIS/05 - Astronomia E AstrofisicaSpace and Planetary ScienceMillisecond pulsarHarmonicStars: Pulsars: General Stars: Pulsars: Individual: Alphanumeric: XTE J1807-294 Stars: Magnetic Fields Stars: Neutron X-Rays: BinariesSpin-½
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Huit objets de cuivre et de bronze du piémont pyrénéen oriental : analyse croisée typologique et métallique

2015

Cet article porte sur huit pièces à base de cuivre – deux haches plates et six poignards – provenant de la zone sous-pyrénéenne orientale (Corbières, Haute Vallée de l’Aude, Pays d’OImes), dans les départements de l’Aude et de l’Ariège de l’Est (région de Lavelanet). Elles sont décrites et replacées dans leur contexte typochronologique, alors que les aspects technoéconomiques sont envisagés via la composition métallique (composition élémentaire et rapports isotopiques du plomb). Cinq objets en cuivre – deux haches et trois poignards – sont attribués au Chalcolithique. L’une des haches se rapproche des types nord-ibériques et son importation depuis cette région est suggérée par les analyses …

pratiques funérairescomposition isotopique du plomb[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistorytrace elementssépulturedaggersépulturesRuscinofoyers à pierres chaufféestypochronologytypochronologielead isotope analysis LIAincinérationComputingMilieux_MISCELLANEOUSMathematicspoignardPyrénéesAxe[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistorylead isotope analysis LIA.DoliumPyreneesGeneral MedicineHachefourbronzecuivrecoppernécropolecomposition élémentaireHumanities
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Mineral Profile of Children’s Fast Food Menu Samples

2017

Abstract Children’s fast food menus, including hamburgers served with french fries, dessert, and a soft drink, were analyzed to obtain the mineral profile of trace elements. The developed analytical methodology involved sample digestion under pressure inside a microwave oven with a mixture of HNO3 and H2O2 and inductively coupled plasma-optical emission spectrometry. The method was validated by carrying out the analysis of certified reference materials (NIST 1570a spinach leaves, NCS ZC73016 chicken, and NIST 1568a rice flour) and using recovery experiments. Repeatability was verified by analyzing replicate samples. Twenty-six elements were studied, 12 of which—aluminum, barium, calcium, co…

0301 basic medicineAdolescentMicrowave ovenchemistry.chemical_element01 natural sciencesAnalytical Chemistry03 medical and health sciencesLimit of DetectionHumansEnvironmental ChemistryFood scienceChildMicrowavesPharmacologyMineralsStrontium030109 nutrition & dieteticsChemistryMagnesiumFrench friesSpectrum Analysis010401 analytical chemistryBariumHydrogen PeroxideRepeatabilityFood AnalysisTrace Elements0104 chemical sciencesCertified reference materialsMetalsChild PreschoolCalibrationFast FoodsAgronomy and Crop ScienceFood AnalysisFood ScienceJournal of AOAC INTERNATIONAL
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Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens

2019

25 Páginas, 7 figuras, 2 tablas

RNA virusesRotavirusViral DiseasesPhysiologyViral Nonstructural ProteinsPathology and Laboratory MedicineCrystallography X-Raymedicine.disease_causeBiochemistryBinding AnalysisReovirusesImmune PhysiologyRotavirusMedicine and Health SciencesChemical PrecipitationBiology (General)Antigens ViralGastroenterologiachemistry.chemical_classification0303 health sciencesImmune System ProteinsCrystallographyMolecular StructurebiologyPhysics030302 biochemistry & molecular biologyChemical ReactionsRNA-Binding ProteinsCondensed Matter PhysicsLigand (biochemistry)Amino acidChemistryInfectious DiseasesMedical MicrobiologyViral PathogensVirusesPhysical SciencesCrystal StructurePathogensCrystallizationResearch ArticleChemical ElementsGlycanQH301-705.5Virus RNAViral proteinImmunologyResearch and Analysis MethodsMicrobiologyABO Blood-Group SystemCell Line03 medical and health sciencesAntigenVirologyGeneticsmedicineSolid State PhysicsHumansAntigensBinding siteMicrobial PathogensMolecular BiologyRotavirus InfectionChemical Characterization030304 developmental biologyChemical PhysicsBinding SitesBiology and life sciencesMutagenesisOrganismsProteinsRC581-607Molecular biologyCarbonchemistrybiology.proteinCapsid ProteinsParasitologyImmunologic diseases. AllergyPLOS Pathogens
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Simulation-based estimation of branching models for LTR retrotransposons

2017

Abstract Motivation LTR retrotransposons are mobile elements that are able, like retroviruses, to copy and move inside eukaryotic genomes. In the present work, we propose a branching model for studying the propagation of LTR retrotransposons in these genomes. This model allows us to take into account both the positions and the degradation level of LTR retrotransposons copies. In our model, the duplication rate is also allowed to vary with the degradation level. Results Various functions have been implemented in order to simulate their spread and visualization tools are proposed. Based on these simulation tools, we have developed a first method to evaluate the parameters of this propagation …

0301 basic medicineStatistics and ProbabilitySource codeTheoretical computer scienceRetroelementsmedia_common.quotation_subjectRetrotransposon[INFO.INFO-SE]Computer Science [cs]/Software Engineering [cs.SE]BiologyBiochemistryGenomeChromosomesBranching (linguistics)[INFO.INFO-IU]Computer Science [cs]/Ubiquitous Computing03 medical and health sciences[INFO.INFO-CR]Computer Science [cs]/Cryptography and Security [cs.CR]SoftwareAnimalsComputer SimulationMolecular BiologyComputingMilieux_MISCELLANEOUSmedia_commoncomputer.programming_languageGeneticsGenomeModels Geneticbusiness.industry[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Python (programming language)[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM][INFO.INFO-MO]Computer Science [cs]/Modeling and SimulationComputer Science ApplicationsVisualizationComputational Mathematics030104 developmental biologyDrosophila melanogasterComputational Theory and Mathematics[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA]Programming Languages[INFO.INFO-ET]Computer Science [cs]/Emerging Technologies [cs.ET]Mobile genetic elements[INFO.INFO-DC]Computer Science [cs]/Distributed Parallel and Cluster Computing [cs.DC]businesscomputerSoftware
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The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation.

1999

Gonadal differentiation is dependent upon a molecular cascade responsible for ovarian or testicular development from the bipotential gonadal ridge. Genetic analysis has implicated a number of gene products essential for this process, which include Sry, WT1, SF-1, and DAX-1. We have sought to better define the role of WT1 in this process by identifying downstream targets of WT1 during normal gonadal development. We have noticed that in the developing murine gonadal ridge, wt1 expression precedes expression of Dax-1, a nuclear receptor gene. We document here that the spatial distribution profiles of both proteins in the developing gonad overlap. We also demonstrate that WT1 can activate the D…

Transcriptional Activationcongenital hereditary and neonatal diseases and abnormalitiesGenes Wilms TumorReceptors Retinoic AcidTATA boxMolecular Sequence DataMutagenesis (molecular biology technique)Biologyurologic and male genital diseasesResponse ElementsTransactivationMiceGene expressionAnimalsHumansGonadsPromoter Regions GeneticWT1 ProteinsMolecular BiologyGeneCell Growth and DevelopmentCell Line TransformedGonadal ridgeBase Sequenceurogenital systemDAX-1 Orphan Nuclear ReceptorfungiGene Expression Regulation DevelopmentalCell Biologyfemale genital diseases and pregnancy complicationsCell biologyDNA-Binding ProteinsRepressor ProteinsTestis determining factorNuclear receptorCOS CellsCancer researchTranscription FactorsMolecular and cellular biology
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Zirconium–hafnium and rare earth element signatures discriminating the effect of atmospheric fallout from hydrothermal input in volcanic lake water

2016

The geochemical behaviour of Rare Earth Elements, Zr and Hf was investigated in the thermal waters of Nevado del Ruiz volcano system. A wide range of pH, between 1.0 and 8.8, characterizes these fluids. The acidicwaters are sulphate dominatedwith different Cl/SO4 ratios. The important role of the pH and the ionic complexes for the distribution of REE, Zr a nd Hf in the aqueous phase was evidenced. The pH rules the precipitation of authigenic Fe and Al oxyhydroxides producing changes in REE, Zr, Hf amounts and strong anomalies of Cerium. The precipitation of alunite and jarosite removes LREE from the solution, changing the REE distribution in acidic waters. Y-Ho and Zr-Hf (twin pairs) have a…

Rare Earth Elements010504 meteorology & atmospheric sciencesGeochemistrychemistry.chemical_element010502 geochemistry & geophysics01 natural sciencesHydrothermal circulationLakeRare earth elements Zirconium Hafnium CO2-rich waters Lake Aeolian inputGeochemistry and Petrology[SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/GeochemistryPrecipitation0105 earth and related environmental sciencesgeographyZirconiumgeography.geographical_feature_categoryCO 2 -rich watersRare-earth elementGeologyAuthigenicHafniumAeolian inputVolcanochemistryZirconiumOil shaleGeologyHafnium
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All-sky search in early O3 LIGO data for continuous gravitational-wave signals from unknown neutron stars in binary systems

2021

Rapidly spinning neutron stars are promising sources of continuous gravitational waves. Detecting such a signal would allow probing of the physical properties of matter under extreme conditions. A significant fraction of the known pulsar population belongs to binary systems. Searching for unknown neutron stars in binary systems requires specialized algorithms to address unknown orbital frequency modulations. We present a search for continuous gravitational waves emitted by neutron stars in binary systems in early data from the third observing run of the Advanced LIGO and Advanced Virgo detectors using the semicoherent, GPU-accelerated, binaryskyhough pipeline. The search analyzes the most s…

binary: orbitneutron star: binaryPhysics and Astronomy (miscellaneous)Astronomybinary [neutron star]AstrophysicsGravitational Waves; LIGO (Observatory); Neutron Stars01 natural sciencesneutron starsGeneral Relativity and Quantum CosmologyMonte Carlo: Markov chainPhysics Particles & Fieldsbinary starsbinary systemsBinary SystemsLIGOgravitational waveQCQBpulsarastro-ph.HEHigh Energy Astrophysical Phenomena (astro-ph.HE)Physicseducation.field_of_studySettore FIS/03Physicsorbit [binary]General relativityPhysical Sciences[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Astrophysics - High Energy Astrophysical Phenomenabinary stardata analysis methodsensitivity [detector]General relativitygr-qcfrequency [modulation]Populationneutron star: spinFOS: Physical sciencesalternative theories of gravityMarkov chain [Monte Carlo]General Relativity and Quantum Cosmology (gr-qc)Astronomy & AstrophysicsGravitational Waves Neutron Stars Binary Systems LIGO VirgoLIGO (Observatory)emission [gravitational radiation]Pulsarbinary: coalescence0103 physical sciencesBinary starddc:530spin [neutron star]background [gravitational radiation]010306 general physicseducationSTFCOrbital elementsGravitational WavesScience & Technology010308 nuclear & particles physicsGravitational waveVirgogravitational radiation: backgroundmodulation: frequencyRCUKNeutron StarsLIGOgravitational radiation detectordetector: sensitivityNeutron starVIRGOgravitational radiation: emissionDewey Decimal Classification::500 | Naturwissenschaften::530 | Physikcoalescence [binary][PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]binary stars; neutron stars
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Production of refractory elements close to the Z=N line using the ion-guide technique

1998

Production of neutron-deficient isotopes of refractory elements in the A = 80-88 region was studied using the IGISOL technique and the 165 MeV Si-32 + Ni-nat reaction. Radioactive isotopes of Y through Mo could be produced up to the M-T = + 1 line. New information on the decay of the A = 82 and 85 nuclei, including a more detailed decay scheme and more accurate half-life for Y-82, was obtained. (C) 1998 Elsevier Science B.V. All rights reserved.

Nuclear and High Energy PhysicsIsotopes of germaniumAnalytical chemistryONLINE[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciencesY-81Isotopes of oxygenNuclear physicsIsotopes of protactinium0103 physical sciencesNEUTRON-DEFICIENT ISOTOPES010306 general physicsInstrumentationIsotopes of europiumPhysicsDecay schemeIsotope010308 nuclear & particles physicsRefractory metalsIGISOL TECHNIQUEheavy-ion fusion-evaporation reactionsBeta decayrefractory elementsbeta decayDECAY
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