Search results for "ether"

showing 10 items of 986 documents

Copper(I) Complexes of Bis(2-(diphenylphosphino)phenyl) Ether:  Synthesis, Reactivity, and Theoretical Calculations

2007

The tricoordinated cationic Cu-I complex [Cu(kappa(2)-P,P'-DPEphos)(kappa(1)-P-DPEphos)][BF4] (1) (DPEphos = bis(2-(diphenylphosphino)phenyl) ether) containing a dangling phosphorus center was synthesized from the reaction of [Cu(CH3CN)(4)][BF4] with DPEphos in a 1:2 molar ratio in dichloromethane. When complex 1 is treated with MnO2, elemental sulfur, or selenium, the uncoordinated phosphorus atom undergoes oxidation to form a PE bond resulting in the formation of complexes of the type [Cu(kappa(2)-P,P'-DPEphos)(kappa(2)-P,E-DPEphos-E)][BF4] (2, E = O; 3, E = S; 4, E = Se) containing a Cu-E bond. The zigzag polymeric Cu-I complex [Cu(kappa(2)-P,P'-DPEphos)(mu-4,4'-bpy)](n)[BF4](n) (5) was …

Inorganic chemistryCu-I ComplexesBite AngleEtherEmitting Electrochemical-CellsBite angleMedicinal chemistryTransition-Metal ChemistryInorganic Chemistrychemistry.chemical_compounddifenyylifosfinoMoleculeReactivity (chemistry)Staudinger reactionPhysical and Theoretical ChemistryMonooxidized Bis(Phosphino)AminesMolecular-StructureStructural-CharacterizationDichloromethaneChemistryCationic polymerizationPlatinum(Ii) Complexeskupari(I) kompleksitWilliamson ether synthesisState Methodcopper(I) complexStaudinger ReactiondiphenylphosphinoInorganic Chemistry
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Highly Efficient Removal of Neonicotinoid Insecticides by Thioether-Based (Multivariate) Metal–Organic Frameworks

2021

Circumventing the impact of agrochemicals on aquatic environments has become a necessity for health and ecological reasons. Herein, we report the use of a family of five eco-friendly water-stable isoreticular metal-organic frameworks (MOFs), prepared from amino acids, as adsorbents for the removal of neonicotinoid insecticides (thiamethoxam, clothianidin, imidacloprid, acetamiprid, and thiacloprid) from water. Among them, the three MOFs containing thioether-based residues show remarkable removal efficiency. In particular, the novel multivariate MOF {SrIICuII6[(S,S)-methox]1.5[(S,S)-Mecysmox]1.50(OH)2(H2O)}·36H2O (5), featuring narrow functional channels decorated with both -CH2SCH3 and -CH2…

InsecticidesMaterials science02 engineering and technologySulfides010402 general chemistry01 natural sciencesAcetamipridWater PurificationNeonicotinoidschemistry.chemical_compoundMethionineAdsorptionThioetherOrganic chemistryGeneral Materials ScienceCysteineMetal-Organic FrameworksSolid Phase ExtractionNeonicotinoidClothianidin021001 nanoscience & nanotechnologyThiacloprid0104 chemical scienceschemistryMetal-organic frameworkAdsorptionThiamethoxam0210 nano-technologyWater Pollutants Chemicalacs applied materials & interfaces
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Intangibles - enhancing access to cities cultural heritage through interpretation

2013

PurposeThe purpose of this paper is to utilise commodification for the conservation and promotion of cultural heritage in cities by developing interpretative strategies, specifically enabling access to intangible cultural heritage through its tangible parts.Design/methodology/approachIn total, three case studies were conducted in the cities of Amsterdam, Genoa and Leipzig, through a workshop cycle with destination and local tourism stakeholders and citizen representatives, to develop interpretative strategies for the cities.FindingsThe paper identifies tangible and intangible cultural heritage of the three cities, and integrates them into stories and outlines the development of an interpret…

Intangible cultural heritageGeography Planning and DevelopmentCultureHeritageGermanySettore SPS/10 - Sociologia Dell'Ambiente E Del TerritorioCommodificationCultural heritage managementHeritage interpretationThe NetherlandIndustrial heritageSociologyMarketingDestination marketingIntangible cultural heritageCommodificationbusiness.industryHeritage interpretationPublic relationsCultural tourismCitieCultural heritageItalyThe Netherlands Italy Germany Cities Heritage Culture Intangible cultural heritage Heritage interpretation Destination marketing CommodificationTourism Leisure and Hospitality ManagementbusinessTourism
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Network Virtualization Based on Effective Packet Transformations

2015

Promocijas darbā ir piedāvātas divas oriģinālas tehnoloģijas, kas paaugstina datortīklu virtualizēšanas efektivitāti: ZERO tunelēšanas protokols, un Pakešu Transformāciju Valoda (Packet Transformation Language, PTL), kas ļauj kompaktā pierakstā formāli aprakstīt ZERO un citus tunelēšanas protokolus. Darbā ir piedāvāts Ethernet-pāri-IP tunelēšanas protokols, kas nodala visus Ethernet kadrus tunelēšanai NICE un UGLY kadros. UGLY kadri tiek tunelēti ar tradicionālām metodēm, kā UDP vai GRE enkapsulācija, kas būtiski palielina kopējo paketes garumu dēļ papildus galvenēm un fragmentēšanas, kas parasti nepieciešama, lai transportētu garus Ethernet kadrus pāri IP datortīklam, kam parasti maksimāla…

InternetEthernetDatu apstrādes sistēmas un datortīklitunnelingstraumes apstrādemākoņdatošanaDatorzinātnesComputer ScienceData processing systems and computer networkscomputer networkstunelēšanadatoru tīkli
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Intracellular Na+ concentration influences short-term plasticity of glutamate transporter-mediated currents in neocortical astrocytes.

2012

Fast synaptic transmission requires a rapid clearance of the released neurotransmitter from the extracellular space. Glial glutamate transporters (excitatory amino acid transporters, EAATs) strongly contribute to glutamate removal. In this work, we investigated the paired-pulse plasticity of synaptically activated, glutamate transporter-mediated currents (STCs) in cortical layer 2/3 astrocytes. STCs were elicited by local electrical stimulation in layer 4 in the presence of ionotropic glutamate (AMPA and NMDA), GABAA, and GABAB receptor antagonists. In experiments with low [Na+]i (5 mM) intrapipette solution, STCs elicited by paired-pulse stimulation demonstrated paired-pulse facilitation (…

Intracellular FluidPatch-Clamp TechniquesAmino Acid Transport System X-AGBiophysicsNipecotic AcidsAction PotentialsNeocortexAMPA receptorTetrodotoxinBiologyGABAB receptorAnisolesIn Vitro TechniquesSynaptic TransmissionGABA AntagonistsCellular and Molecular NeuroscienceMiceCadmium ChlorideEthers CyclicOximesmedicineGABA transporterAnimalsgamma-Aminobutyric AcidBenzofuransAspartic AcidNeuronal PlasticityGABAA receptorRhodaminesSodiumGlutamate receptorCalcium Channel BlockersElectric StimulationMice Inbred C57BLmedicine.anatomical_structureNeurologyAnimals NewbornAstrocytesExcitatory postsynaptic potentialBiophysicsbiology.proteinNMDA receptorNeuroscienceExcitatory Amino Acid AntagonistsAstrocyteSodium Channel BlockersGlia
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Influence of calcium on the effects of okadaic acid and its interaction with caffeine and theophylline in rat myometrium.

1994

The effects of okadaic acid (OA), a monocarboxylic acid produced by marine dinoflagellates belonging to the genera Dinophysis and Prorocentrum, and their interactions with theophylline and caffeine were studied on the rat-isolated uterus in a calcium-containing medium and a calcium-free medium in the presence of 10−3 M EGTA. Okadaic acid (5 × 10−6 to 5 × 10−5 M) induced a concentration-dependent contraction of the rat-isolated uterus corresponding, with 5 × 10−5M, to 142.3±6.1% (n = 7) of the contraction induced by oxytocin 10−6 M. The time to peak tension was inversely proportional to the maximum effect produced. The contraction was not sustained and was followed by a concentration-depende…

Intracellular Fluidmedicine.medical_specialtyContraction (grammar)Time Factorschemistry.chemical_elementCalciumRats Sprague-Dawleychemistry.chemical_compoundUterine ContractionTheophyllineEthers CyclicInternal medicineCaffeinePapaverineOkadaic AcidmedicineAnimalsTheophyllineDrug InteractionsPharmacologyCalcium metabolismColforsinMyometriumGeneral MedicineOkadaic acidRatsEGTAEndocrinologychemistryBiochemistryMyometriumCalciumFemaleCaffeineExtracellular Spacemedicine.drugNaunyn-Schmiedeberg's archives of pharmacology
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Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells

2015

Abstract Background Apoptosis and other forms of cell death have been intensively investigated in the past years to explain the mode of action of synthetic anticancer drugs and natural products. Recently, a new form of cell death emerged, which was termed ferroptosis, because it depends on intracellular iron. Here, the role of genes involved in iron metabolism and homeostasis for the cytotoxicity of ten artemisinin derivatives have been systematically investigated. Material and methods Log10IC50 values of 10 artemisinin derivatives (artesunate, artemether, arteether, artenimol, artemisitene, arteanuin B, another monomeric artemisinin derivative and three artemisinin dimer molecules) were co…

IronArtesunatePharmaceutical ScienceApoptosisTransferrin receptorDeferoxaminePhenylenediaminesPharmacologyBiologyInhibitory Concentration 50chemistry.chemical_compoundCell Line Tumorparasitic diseasesDrug DiscoverymedicineHumansArtemetherArtemisininCytotoxicityOligonucleotide Array Sequence AnalysisPharmacologychemistry.chemical_classificationCyclohexylaminesCell DeathMolecular StructureArtemisinin DimerArtemisininsGene Expression Regulation NeoplasticComplementary and alternative medicinechemistryApoptosisTransferrinArtesunateMolecular MedicineArtemethermedicine.drugPhytomedicine
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Lagrangian dynamics and possible isochronous behavior in several classes of non-linear second order oscillators via the use of Jacobi last multiplier

2015

Abstract In this paper, we employ the technique of Jacobi Last Multiplier (JLM) to derive Lagrangians for several important and topical classes of non-linear second-order oscillators, including systems with variable and parametric dissipation, a generalized anharmonic oscillator, and a generalized Lane–Emden equation. For several of these systems, it is very difficult to obtain the Lagrangians directly, i.e., by solving the inverse problem of matching the Euler–Lagrange equations to the actual oscillator equation. In order to facilitate the derivation of exact solutions, and also investigate possible isochronous behavior in the analyzed systems, we next invoke some recent theoretical result…

Isochronous dynamicConservation lawApplied MathematicsMechanical EngineeringMathematical analysisAnharmonicityIsotonic potentialJacobi Last Multiplier (JLM)Simple harmonic motionInverse problemMultiplier (Fourier analysis)Nonlinear systemsymbols.namesakeSimple harmonic oscillatorMechanics of MaterialssymbolsNoether's theoremSettore MAT/07 - Fisica MatematicaLagrangianConservation lawsVariable (mathematics)MathematicsInternational Journal of Non-Linear Mechanics
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Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives

2011

Microtubules are dynamic structures that play a crucial role in cellular division and are recognized as an important target for cancer therapy. In search of new compounds with strong antiproliferative activity and simple molecular structure, a new series of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-(hetero)aryl ethynyl thiophene derivatives was prepared by the Sonogashira coupling reaction of the corresponding 5-bromothiophenes with several (hetero)aryl acetylenes. When these compounds were analyzed in vitro for their inhibition of cell proliferation, the 2- and 3-thiophenyl acetylene derivatives were the most powerful compounds, both of which exerted cytostatic effects at submicromolar conc…

KetoneCell divisionStereochemistryClinical BiochemistryPharmaceutical ScienceSonogashira couplingUterine Cervical NeoplasmsEthermacromolecular substancesThiophenesAntimitotic AgentsBiochemistryChemical synthesisArticlechemistry.chemical_compoundMiceStructure-Activity RelationshipThiopheneCell Line TumorDrug DiscoveryThiopheneAnimalsHumansInhibition of tumor cell growthMolecular BiologyCell Proliferationchemistry.chemical_classificationLeukemiaMolecular StructureInhibition of tubulin polymerizationCell growthArylOrganic ChemistryAntiproliferative agentsAntiproliferative agents; Inhibition of tubulin polymerization; Inhibition of tumor cell growth; Thiophene;chemistryMolecular MedicineFemale
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ChemInform Abstract: Chemometrics: An Important Tool for the Modern Chemist, an Example from Wood-Processing Chemistry.

2010

This study briefly outlines the idea of principal component analysis and cross-correlation calculations (applied chemometrics) and presents an illustrative example from wood-processing chemistry. The applicability of chemometric data analysis was demonstrated by investigating the various structural changes that take place in dissolved and degraded lignin ("kraft lignin") during laboratory-scale kraft pulping of Scots pine (Pinus sylvestris) and silver birch (Betula pendula). The structural data (31P NMR and size exclusion chromatographic data) on kraft lignin were further processed by chemometric multivariate techniques (PCA and 2DCC), confirming, for example, that the cleavage of beta-aryl…

Kraft ligninChemometricschemistry.chemical_compoundKraft processChemistryWood processingBetula pendulaPrincipal component analysisLigninEtherGeneral MedicinePulp and paper industryChemInform
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