Search results for "ether"

showing 10 items of 986 documents

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumpti…

2011

Alcohol consumption is a moderately heritable trait, but the genetic basis in humans is largely unknown, despite its clinical and societal importance. We report a genome-wide association study meta-analysis of ∼2.5 million directly genotyped or imputed SNPs with alcohol consumption (gram per day per kilogram body weight) among 12 population-based samples of European ancestry, comprising 26,316 individuals, with replication genotyping in an additional 21,185 individuals. SNP rs6943555 in autism susceptibility candidate 2 gene ( AUTS2 ) was associated with alcohol consumption at genome-wide significance ( P = 4 × 10 −8 to P = 4 × 10 −9 ). We found a genotype-specific expression of AUTS2 in 9…

Netherlands Twin Register (NTR)alcohol consumptionPopulationautismSingle-nucleotide polymorphismGenome-wide association studygenome-wide analysis; epidemiologic; transcriptional expression analysis; alcohol consumption; autismBiologyQuantitative trait locus03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingADDICTIVE BEHAVIORDEPENDENCEGenotype/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_medicineSNPeducationGenotyping030304 developmental biologyGenetics0303 health scienceseducation.field_of_studyMultidisciplinaryepidemiologicMENAlcohol Drinking/genetics; Alcohol Drinking/metabolism; Animals; Drosophila melanogaster/genetics; Drosophila melanogaster/metabolism; European Continental Ancestry Group/genetics; Female; Gene Expression Regulation/genetics; Genome-Wide Association Study; Genotype; Humans; Male; Mice; Nuclear Proteins/biosynthesis; Nuclear Proteins/genetics; Polymorphism Single Nucleotide; Proteins/genetics; Proteins/metabolism; Quantitative Trait HeritableBiological Sciencesmedicine.diseaseGENOTYPES3. Good healthDROSOPHILA/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingAutismtranscriptional expression analysis030217 neurology & neurosurgerygenome-wide analysisProceedings of the National Academy of Sciences of the U.S.A.
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Competitive interaction of three peroxidizing herbicides with the binding of 3H acifluorfen to corn etioplast membranes

1990

AbstractThe specific binding of the herbicide acifluorfen 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid to corn etioplast membranes is competitively inhibited by protoporphyrinogen IX, the substrate of protoporphyrinogen oxidase. Three other peroxidizing molecules, oxadiazon [5-ter-butyl-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2-one], LS 82556 [(S)3-N-(methylbenzyl)carbamoyl-5-propionyl-2,6-lutidine], and M&B 39279 [5-amino-4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazol], also compete with acifluorfen for its binding site. The four herbicides thus bind to the same site, or to closely located sites, on the enzyme protoporphyrinogen oxidase.

Niacinamide0106 biological sciencesOxidoreductases Acting on CH-CH Group DonorsStereochemistryBiophysics[SDV.BC]Life Sciences [q-bio]/Cellular BiologyAcifluorfenBinding CompetitiveZea mays01 natural sciencesBiochemistry03 medical and health scienceschemistry.chemical_compoundEtioplastStructural BiologyDiphenyletherGeneticsBinding site[SDV.BC] Life Sciences [q-bio]/Cellular BiologyMolecular BiologyComputingMilieux_MISCELLANEOUS030304 developmental biologychemistry.chemical_classificationOxadiazoles0303 health sciencesBinding SitesTrifluoromethylHerbicidesCell MembraneCell BiologyPlantsBindingProtoporphyrinogen IXProtoporphyrinogen oxidaseEnzymeMembranechemistryDiuronNitrobenzoatesPyrazolesProtoporphyrinogen oxidaseHerbicideOxidoreductases010606 plant biology & botany
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On two topological cardinal invariants of an order-theoretic flavour

2012

Noetherian type and Noetherian $\pi$-type are two cardinal functions which were introduced by Peregudov in 1997, capturing some properties studied earlier by the Russian School. Their behavior has been shown to be akin to that of the \emph{cellularity}, that is the supremum of the sizes of pairwise disjoint non-empty open sets in a topological space. Building on that analogy, we study the Noetherian $\pi$-type of $\kappa$-Suslin Lines, and we are able to determine it for every $\kappa$ up to the first singular cardinal. We then prove a consequence of Chang's Conjecture for $\aleph_\omega$ regarding the Noetherian type of countably supported box products which generalizes a result of Lajos S…

NoetherianHigher Suslin LinePixley–Roy hyperspacePrimary: 03E04 54A25 Secondary: 03E35 54D70LogicOpen setMathematics::General TopologyDisjoint setsTopological spaceType (model theory)TopologyChangʼs ConjectureChangʼs Conjecture for ℵωFOS: MathematicsBox productMathematicsMathematics - General TopologyConjectureMathematics::Commutative AlgebraGeneral Topology (math.GN)PCF theoryNoetherian typeMathematics - LogicInfimum and supremumMathematics::LogicOIF spaceLogic (math.LO)
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The Argo YBJ daq system and the GRID based data transfer

2008

The Argo-YBJ experiment has now reached itsfinal design configuration. The detector system consists of a fullcoverage array (about 5800 square meters) of Resistive PlateChambers (RPCs). The throughput depends on the trigger rateand threshold. The DAQ system must be able to sustain a max-imum transfer rate of the order of 15 MB/s and a high peakdata flow. Data are read out using a typical front-end acquisitionchain built around a custom bus. Specialized electronics have beendesigned and dedicated software has been written to perform thistask. Data are sent to the online farm through a switch exploitinga gigabit ethernet protocol. A solution to transfer data from theYBJ laboratory to the labo…

Nuclear and High Energy PhysicsEngineeringbusiness.industryGigabit Ethernetcomputer.software_genreGridData flow diagramData acquisitionNuclear Energy and EngineeringGrid computingNuclear electronicsData acquisition data mover GRID RPCElectrical and Electronic EngineeringbusinessThroughput (business)computerComputer hardwareData transmission
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Production of plutonium tracers in 237Np nuclear reactions with 3He-ions in the energy range from 26 to 60 MeV

1998

Cross-sections for the reaction Np-237 + He-3 --> Pu-236,Pu-237,Pu-238 at He-3 bombarding energies from 26 to 60 MeV were measured. Thick-target yields, based on the measured and previously known cross-sections were constructed. The results are discussed and compared with Ether reactions leading to the formation of the same final nuclei. (C) 1998 Elsevier Science S.A.

Nuclear reactionRange (particle radiation)ProtonMechanical EngineeringRadiochemistryMetals and Alloyschemistry.chemical_elementEtherActinide010403 inorganic & nuclear chemistry01 natural sciences7. Clean energy030218 nuclear medicine & medical imaging0104 chemical sciencesPlutoniumIon03 medical and health scienceschemistry.chemical_compound0302 clinical medicinechemistryMechanics of MaterialsMaterials ChemistryPlutonium-238Journal of Alloys and Compounds
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Breast-cancer predisposition in multiple endocrine neoplasia type 1

2014

Women with multiple endocrine neoplasia type 1 related to mutations in the gene encoding menin (MEN1) have approximately twice the risk of breast cancer as do women in the general population.

OncologyAdultRiskcongenital hereditary and neonatal diseases and abnormalitiesendocrine systemmedicine.medical_specialtyendocrine system diseasesGenotypePopulationVascular damage Radboud Institute for Health Sciences [Radboudumc 16]Breast Neoplasmsmedicine.disease_causeArticleBreast cancerSDG 3 - Good Health and Well-beingInternal medicineProto-Oncogene ProteinsGenotypemedicineCarcinomaMultiple Endocrine Neoplasia Type 1HumansMEN1Genetic Predisposition to DiseaseLongitudinal StudiesMultiple endocrine neoplasiaeducationGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)GeneNetherlandsMutationeducation.field_of_studybusiness.industryCarcinoma Ductal BreastGeneral MedicineMiddle Agedmedicine.diseaseCarcinoma PapillaryImmunologyMutationFemalebusiness
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Influencia del procesado industrial sobre las características químico-físicas y contenido en lípidos y antioxidantes del salvado de arroz

2009

Se investigaron las características químico-físicas de los salvados de arroz en distintos momentos de su procesado industrial, incluyendo materia prima (salvados de arroz blanco y vaporizado), salvado peletizado y salvado desgrasado. Se determinó la humedad, la acidez y el índice de peróxidos. Utilizando extractos en éter de petróleo y cromatografía de gases, se estableció el contenido lipídico total y los perfiles de los ácidos grasos. Mediante HPLC se determinaron los tocoferoles y el γ-orizanol. El salvado de arroz vaporizado mostró la mayor concentración de lípidos y la menor acidez, lo que indica que el vaporizado es el proceso más eficaz para estabilizar el salvado. Los ácidos oleico,…

OrizanolBranLinoleic acidUNESCO::QUÍMICAdigestive oral and skin physiologyOrganic Chemistryfood and beveragesÁcidos grasos; Características químico-físicas; Orizanol; Procesado del salvado; Salvado de arroz; TocoferolesProcesado del salvadoHigh-performance liquid chromatography:QUÍMICA [UNESCO]TocoferolesFerulic acidPalmitic acidCaracterísticas químico-físicaschemistry.chemical_compoundOleic acidchemistrylipids (amino acids peptides and proteins)Petroleum etherFood scienceSalvado de arrozParboilingÁcidos grasosFood Science
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Design of experiment approach for the optimization of polybrominated diphenyl ethers determination in fine airborne particulate matter by microwave-a…

2015

Abstract A sensitive and selective procedure for the determination of 12 polybrominated diphenyl ethers (BDE-28, BDE-49, BDE-47, BDE-66, BDE-100, BDE-119, BDE-99, BDE-155, BDE-154, BDE-153, BDE-139 and BDE-183) in airbone particulate matter (PM2.5) at trace level has been developed. The proposed method includes extraction PM2.5-bound PBDEs by microwave-assisted extraction (MAE) followed by gel permeation chromatography (GPC) clean-up and determination by GC-MS/MS using a programmed temperature vaporizer (PTV) in large volume injection (LVI) mode to introduce the sample to the chromatographic system. A design of experiment (DoE) approach was used for the optimization of large volume injectio…

PBDEsAnalytical chemistryPM2.5Tandem mass spectrometryBiochemistryMicrowave assisted extraction (MAE);Gas Chromatography-Mass SpectrometryAnalytical ChemistryGel permeation chromatographyPolybrominated diphenyl ethersTandem Mass SpectrometryHalogenated Diphenyl EthersMicrowavesDetection limitProgrammed temperature vaporizer (PTV)ChromatographyChemistryOrganic ChemistryExtraction (chemistry)TemperatureGeneral MedicineVolume (thermodynamics)SpainParticulate MatterVaporizerGas chromatographyGC-MS/MS; Experimental designJournal of chromatography. A
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Resource or waste? A perspective of plastics degradation in soil with a focus on end-of-life options.

2018

‘Capable-of-being-shaped’ synthetic compounds are prevailing today over horn, bone, leather, wood, stone, metal, glass, or ceramic in products that were previously left to natural materials. Plastic is, in fact, economical, simple, adaptable, and waterproof. Also, it is durable and resilient to natural degradation (although microbial species capable of degrading plastics do exist). In becoming a waste, plastic accumulation adversely affects ecosystems. The majority of plastic debris pollutes waters, accumulating in oceans. And, the behaviour and the quantity of plastic, which has become waste, are rather well documented in the water, in fact. This review collects existing information on pla…

PLA polylactic acidPS polystyreneETS European Emissions Trading schemePOM polyoxymethyleneHMC heat melt compactor technology02 engineering and technology010501 environmental sciencesNHV net habitable volumeLDPE low-density polyethylene01 natural sciencesPC polycarbonateResin identification codeLCP liquid crystal polymerslcsh:Social sciences (General)PAC pro-oxidant additive containingPET polyethylene terephthalateEPR Extended Producers ResponsibilityMultidisciplinaryWaste managementNatural materials021001 nanoscience & nanotechnologyPU or PUR polyurethaneSettore AGR/02 - Agronomia E Coltivazioni ErbaceeEPS expandable polystyreneRIC resin identification codeSettore AGR/14 - PedologiaPVDF polydifluoroethylenelcsh:H1-990210 nano-technologyBiogeoscienceGPPS Polystyrene (General Purpose)PVC polyvinyl chlorideResource (biology)Polymethyl methacrylatePA polyamidePBT polybutylene terephthalatePSU polyarylsulfonePTFE polytetrafluoroethylenePMMA polymethyl methacrylatePHA polyhydroxyalkanoateMicrobiologyPEEK polyaryletheretherketoneArticleEnvironmental scienceEnvironmental science Biogeoscience Industry MicrobiologyPPA polyphthalamideTPE thermoplastic polyester elastomerNatural degradationIndustryPPS polyphenylene sulphidelcsh:Science (General)ABS acrylonitrile-butadiene-styrene0105 earth and related environmental sciencesbusiness.industryPP polypropyleneHDPE high-density polyethyleneBPA bisphenol AHBCD hexabromocyclododecaneFuture studyAgricultureDOM dissolved organic matterDegradation (geology)Environmental sciencebusinesslcsh:Q1-390Heliyon
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The landscape of strongholds

2016

La difesa dei territori ha offerto risultati straordinari alla formazione e alla trasformazione del territorio e del paesaggio, a volte con tratti spettacolari e dimensioni incredibili. La celebrazione del centenario dell’inizio della Prima guerra mondiale ha offerto lo spunto per una riflessione sulle ricadute indotte sul paesaggio dagli eventi bellici, e più in generale dalla realizzazione di strutture difensive e del loro rapporto con il paesaggio circostante. Territorial defence led to extraordinary results in terms of forming and transforming the territory and landscape, at times with spectacular sights and incredible sizes. The one hundred year anniversary since the beginning of the F…

Paesaggio guerra trasformazioni difese muraglia canali fortezze fortificazioni canali linee d'acquaSettore ICAR/15 - Architettura Del PaesaggioLandscape strongholds waterline Great Wall Netherlands transformations land ground borders
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