Search results for "evoked potentials"
showing 10 items of 572 documents
Localization of Brain Networks Engaged by the Sustained Attention to Response Task Provides Quantitative Markers of Executive Impairment in Amyotroph…
2020
Abstract Objective: To identify cortical regions engaged during the sustained attention to response task (SART) and characterize changes in their activity associated with the neurodegenerative condition amyotrophic lateral sclerosis (ALS). Methods: High-density electroencephalography (EEG) was recorded from 33 controls and 23 ALS patients during a SART paradigm. Differences in associated event-related potential peaks were measured for Go and NoGo trials. Sources active during these peaks were localized, and ALS-associated differences were quantified. Results: Go and NoGo N2 and P3 peak sources were localized to the left primary motor cortex, bilateral dorsolateral prefrontal cortex (DLPFC),…
Is that me in the mirror? Depersonalisation modulates tactile mirroring mechanisms
2016
Our sense of self is thought to develop through sensory-motor contingencies provided, not only by observing one's own body, but also by mirroring interactions with others. This suggests that there is a strong link between mirroring mechanisms and the bodily self. The present study tested whether this link is expressed at early, implicit stages of the mirroring process or at later, more cognitive stages. We also provide, to the best of our knowledge, the first demonstration of how inter-individual differences in our sense of bodily self may affect mirroring mechanisms. We used somatosensory event-related potentials (SEPs) to investigate the temporal dynamics of mirroring highly self-related …
Asymmetry in the human primary somatosensory cortex and handedness.
2003
Brain asymmetry is a phenomenon well known for handedness and language specialization and has also been studied in motor cortex. Less is known about hemispheric asymmetries in the somatosensory cortex. In the present study, we systematically investigated the representation of somatosensory function analyzing early subcortical and cortical somatosensory-evoked potentials (SEP) after electrical stimulation of the right and left median nerve. In 16 subjects, we compared thresholds, the peripheral neurogram at Erb point, and, using MRI-based EEG source analysis, the P14 brainstem component as well as N20 and P22, the earliest cortical responses from the primary sensorimotor cortex. Handedness w…
Neural correlates of hemispheric dominance and ipsilaterality within the vestibularsystem
2007
Earlier functional imaging studies on the processing of vestibular information mainly focused on cortical activations due to stimulation of the horizontal semicircular canals in right-handers. Two factors were found to determine its processing in the temporo-parietal cortex: a dominance of the non-dominant hemisphere and an ipsilaterality of the neural pathways. In an investigation of the role of these factors in the vestibular otoliths, we used vestibular evoked myogenic potentials (VEMPs) in a fMRI study of monaural saccular-otolith stimulation. Our aim was to (1) analyze the hemispheric dominance for saccular-otolith information in healthy left-handers, (2) determine if there is a predom…
Early use of phonological codes in deaf readers: An ERP study.
2017
Previous studies suggest that deaf readers use phonological information of words when it is explicitly demanded by the task itself. However, whether phonological encoding is automatic remains controversial. The present experiment examined whether adult congenitally deaf readers show evidence of automatic use of phonological information during visual word recognition. In an ERP masked priming lexical decision experiment, deaf participants responded to target words preceded by a pseudohomophone (koral - CORAL) or an orthographic control prime (toral - CORAL). Responses were faster for the pseudohomophone than for the orthographic control condition. The N250 and N400 amplitudes were reduced fo…
Both contextual regularity and selective attention affect the reduction of precision‐weighted prediction errors but in distinct manners
2020
Predictive coding model of perception postulates that the primary objective of the brain is to infer the causes of sensory inputs by reducing prediction errors (i.e., the discrepancy between expected and actual information). Moreover, prediction errors are weighted by their precision (i.e., inverse variance), which quantifies the degree of certainty about the variables. There is accumulating evidence that the reduction of precision-weighted prediction errors can be affected by contextual regularity (as an external factor) and selective attention (as an internal factor). However, it is unclear whether the two factors function together or separately. Here we used electroencephalography (EEG) …
All Talk and No Action: A Transcranial Magnetic Stimulation Study of Motor Cortex Activation during Action Word Production
2004
AbstractA number of researchers have proposed that the premotor and motor areas are critical for the representation of words that refer to actions, but not objects. Recent evidence against this hypothesis indicates that the left premotor cortex is more sensitive to grammatical differences than to conceptual differences between words. However, it may still be the case that other anterior motor regions are engaged in processing a word's sensorimotor features. In the present study, we used singleand paired-pulse transcranial magnetic stimulation to test the hypothesis that left primary motor cortex is activated during the retrieval of words (nouns and verbs) associated with specific actions. W…
Low-frequency rTMS inhibitory effects in the primary motor cortex: Insights from TMS-evoked potentials
2014
The neuromodulatory effects of repetitive transcranial magnetic stimulation (rTMS) have been mostly investigated by peripheral motor-evoked potentials (MEPs). New TMS-compatible EEG systems allow a direct investigation of the stimulation effects through the analysis of TMS-evoked potentials (TEPs).We investigated the effects of 1-Hz rTMS over the primary motor cortex (M1) of 15 healthy volunteers on TEP evoked by single pulse TMS over the same area. A second experiment in which rTMS was delivered over the primary visual cortex (V1) of 15 healthy volunteers was conducted to examine the spatial specificity of the effects. Single-pulse TMS evoked four main components: P30, N45, P60 and N100. M…
Animacy matters: ERP evidence for the multi-dimensionality of topic-worthiness in Chinese
2013
Abstract An event-related potential (ERP) study was conducted to investigate how animacy interacts with givenness during topic processing. Both animacy and givenness have been considered as within-discourse factors that contribute to an element׳s potential to form an optimal topic (i.e., topic-worthiness). ERPs were recorded while participants read question–answer pairs, of which the target sentence induced either a continuation or an alternation of a previously introduced topic (i.e., given vs. new). Depending on the context, a potential topic further differed in its animacy from the preceding one (i.e., animate vs. inanimate). The data revealed a robust givenness effect with an N400 reduc…
Object switching within working memory is reflected in the human event-related brain potential
2008
In two experiments applying a memory updating task subjects are asked to perform several arithmetic operations on stored numbers. From a trial-to-trial perspective these operations could be either performed on a previously processed item or on a new item which requires an object switch in working memory. Object switching results in prolonged operation times; these operation time costs reflect the switch of the focus of attention to the relevant information. Event-related brain potentials obtained in object switch trials show an increased P3a around 300 ms and a late, central negative component between 400 ms and 500 ms. The data suggest that the P3a may reflect the unhitching of the focus o…