Search results for "fiber"

Imbalance between sympathetic and sensory innervation in peritoneal endometriosis

2011

To investigate possible mechanisms of pain pathophysiology in patients with peritoneal endometriosis, a clinical study on sensory and sympathetic nerve fibre sprouting in endometriosis was performed. Peritoneal lesions (n= 40) and healthy peritoneum (n= 12) were immunostained and analysed with anti-protein gene product 9.5 (PGP 9.5), anti-substance P (SP) and anti-tyrosine hydroxylase (TH), specific markers for intact nerve fibres, sensory nerve fibres and sympathetic nerve fibres, respectively, to identify the ratio of sympathetic and sensory nerve fibres. In addition, immune cell infiltrates in peritoneal endometriotic lesions were analysed and the nerve growth factor (NGF) and interleuki…

Serotoninergic innervation of nonprincipal cells in the cerebral cortex of the lizard Podarcis hispanica.

2004

The mechanism of serotoninergic transmission in the neo- and archicortex of mammals kis complex, including both synaptic and nonsynaptic components, direct actions on principal cells, and indirect effects mediated by GABAergic interneurons. Here we studied the termination pattern and synaptic organization of the serotoninergic afferents in the cerebral cortex of the lizard, Podarcis hispanica, which is considered to correspond in part to the mammalian hippocampal formation, with the aim of unraveling basic, phylogenetically preserved rules in the connectivity of this pathway. We demonstrate that serotoninergic afferents, visualized by immunostaining for serotonin itself, establish multiple …

Nature log-analytique du volume des sous-analytiques

2000

Using a preparation theorem for subanalytic functions and Lipschitz stratification for compact subanalytic sets we prove that volumes of slices of globally subanalytic sets and density have a log-analytic nature. We also prove that the set of parameters for which the volume of fiber is finite is globally subanalytic.

Monitoring soft tissue coagulation by optical spectroscopy

2017

Laser tissue welding (LTW) or laser tissue soldering (LTS) is investigated since many years for treatment of incisions, wound closure and anastomosis of vessels [1, 2]. Depending on the process, a certain temperature in the range between 65 °C to 85 °C must be reached and held for a few seconds. Care has to be taken not to overheat the tissue, otherwise necrosis or tissue carbonization may occur and will impair wound healing. Usually the temperature is monitored during the process to control the laser power [3]. This requires either bulky equipment or expensive and fragile infrared fibers to feed the temperature signal to an infrared detector. Alternatively, changes in tissue morphology can…

Advanced electrospun matrices based on polysaccharide derivatives for applications in regenerative medicine

2021

The complete regeneration of damaged human tissues and organs is still a significant challenge. The integrative use of biomaterials, cells and bioactive factors in all-in-one devices exploits all current knowledge of materials science, nanotechnology and stem cell biology to best mimic the complex hierarchical architecture of native tissues. The artificial microenvironment design must be properly tuned to match the physicochemical features of the target, offering adequate nanoscale patterns and biological domains for cellular interactions. Scaffolds must promote and guide the regeneration route by mimicking host signalling pathways through the controlled release and retention of drugs or gr…

Microfibers and Nanoparticles with Controlled Dimensions of a Hyaluronic Acid Derivative

2017

Microfluidics is defined as the technology that deals with the precise control and manipulation of small quantities of fluids constrained in micro-channels of small cross-sectional dimensions [1]. Microfluidics has recently emerged as a very promising route for the production of polymeric fibers at the micro and nanoscale, providing a fine control over fiber shape, size, chemical anisotropy and biological activity [2]. Furthermore, the ability to manipulate nanoliter volumes of liquid and to control mixing and reaction precisely, opens up the possibility of creating smart targeted drug delivery systems as nanoparticles, especially with uniform and narrow size distribution [3]. This work des…

FRP-Substrate bonding quality investigation making use of ultrasonic waves

2016

Fiber reinforced polymer (FRP) composite systems are widely used to repair structurally deficient constructions thanks to their good immunity to corrosion, low weight and excellent mechanical properties. The quality of the FRP-substrate interface bond is a crucial parameter affecting the performance of retrofitted structures. In this framework, ultrasonic testing could be used to assess the quality of the bonding [1-2]. In the case of FRP laminates adhesively bonded to roughly inhomogeneous materials, such as concrete, high scattering attenuation occurs due to the presence of heterogeneities. The concrete behaves almost like a perfect absorber generating a considerable number of short-space…

Prediction of concrete materials compressive strength using surrogate models

2022

Using soft computing methods could be of great interest in predicting the compressive strength of Ultra-High-Performance Fibre Reinforced Concrete (UHPFRC). Therefore, this study developed four soft computing techniques. The models are the Linear- relationship (LR), pure quadratic, M5P-tree (M5P), and artificial neural network (ANN). The models were trained and developed using 306 datasets comprising 11 input parameters, including the curing temperature (T), the water-to-cement ratio (w/c), silica fume (SF), cement content (C), fiber content (Fb), water (W), sand content (S), superplasticizer (SP), fiber aspect ratio (AR) and curing time (t). Experimental results were used and compared to t…

A model for SFRC beams without shear reinforcement

2008

In this paper a physical model, for the prediction of ultimate shear strength of Steel Fibers Reinforced Concrete (SFRC) beams is developed from the plastic Crack Sliding Model (CSM) introduced by Zhang (1997), based on the hypothesis that cracks can be transformed into yield lines. In this work the effectiveness factors are recalculated for SFRC beams and some further developments are introduced in the CSM, taking into account the fundamental post cracking tensile strength contribute of SFRC. The proposed model is validate by a large set of tests collected in literature and some numerical analyses were carried out to show the influence of fibers on the failure beams mode.

Compressive response of concrete columns under service conditions strengthened by confining devices: from the local to the global behavior.

Il rinforzo di colonne in calcestruzzo armato tramite materiali polimerici fibrorinforzati (FRP) o tramite incamiciature in acciaio conferisce agli elementi strutturali degli edifici esistenti un elevato incremento di capacità portante e deformativa grazie alle proprietà dei materiali che svolgono la funzione di confinamento. Conoscere adeguatamente le proprietà meccaniche degli elementi in calcestruzzo confinato risulta di fondamentale importanza nell’ambito di un progetto di sistemi di rinforzo strutturale. Tuttavia, le normative attualmente vigenti non forniscono prescrizioni su come tenere in considerazione la presenza dei carichi di esercizio sugli elementi strutturali al momento dell’…