Search results for "first"

showing 10 items of 1149 documents

Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites: A Meta-analysis of Individual Patient Data

2007

Several randomized controlled trials have compared a transjugular intrahepatic portosystemic shunt (TIPS) with large-volume paracentesis in cirrhotic patients with refractory ascites. Although all agree that TIPS reduces the recurrence rate of ascites, survival is controversial. The aim of this study was to compare the effects of TIPS and large-volume paracentesis in cirrhotic patients with refractory ascites by means of meta-analysis of individual patient data from 4 randomized controlled trials.The study population consisted of 305 patients: 149 allocated to TIPS and 156 to paracentesis. Cumulative probabilities of transplant-free survival and of hepatic encephalopathy (HE) were estimated…

Liver CirrhosisMalemedicine.medical_specialtymedicine.medical_treatmentKaplan-Meier EstimateGastroenterologySpontaneous bacterial peritonitisModel for End-Stage Liver DiseaseHepatorenal syndromeRisk FactorsInternal medicineAscitesmedicineParacentesisHumansParacentesisHepatic encephalopathyAgedFirst episodeHepatologymedicine.diagnostic_testbusiness.industrySodiumGastroenterologyAscitesBilirubinPatient dataMiddle Agedmedicine.diseaseLiver TransplantationSurgeryTreatment OutcomeMeta-analysisHepatic EncephalopathyRegression AnalysisFemaleRefractory ascitesPortasystemic Shunt Transjugular Intrahepaticmedicine.symptombusinessTransjugular intrahepatic portosystemic shuntGastroenterology
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Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis : A longitudinal study of 1893 biopsy-proven no…

2021

[Background and Aim] Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) features, which is one of the leading causes of screening failure in clinical trials. We assessed the NASH distribution and its components across the fibrosis stages and their impact on the prognosis and their relationship with the concept of metabolic-associated fatty liver disease (MAFLD).

Liver Cirrhosismedicine.medical_specialtyCirrhosisSteatosisBiopsyGastroenterologydigestive systemBallooning03 medical and health sciencesLiver disease0302 clinical medicineNon-alcoholic Fatty Liver DiseaseFatty liver diseaseInternal medicineBiopsyNonalcoholic fatty liver diseasemedicineassociated fatty liver diseaseMetabolic-associated fatty liver diseaseHumansmetabolic&#8208Longitudinal StudiesFirst episodeInflammationHepatologymedicine.diagnostic_testballooning fatty liver disease inflammation metabolic-associated fatty liver disease natural coursesteatohepatitis steatosisbusiness.industryFatty liverNatural coursesteatohepatitismedicine.diseasedigestive system diseasesLiver030220 oncology & carcinogenesis030211 gastroenterology & hepatologySteatosisSteatohepatitisbusiness
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The fluted fragment revisited

2019

AbstractWe study the fluted fragment, a decidable fragment of first-order logic with an unbounded number of variables, motivated by the work of W. V. Quine. We show that the satisfiability problem for this fragment has nonelementary complexity, thus refuting an earlier published claim by W. C. Purdy that it is in NExpTime. More precisely, we consider ${\cal F}{{\cal L}^m}$, the intersection of the fluted fragment and the m-variable fragment of first-order logic, for all $m \ge 1$. We show that, for $m \ge 2$, this subfragment forces $\left\lfloor {m/2} \right\rfloor$-tuply exponentially large models, and that its satisfiability problem is $\left\lfloor {m/2} \right\rfloor$-NExpTime-hard. We…

Logic0102 computer and information sciencesQuine01 natural sciences68Q17Fragment (logic)0101 mathematicstransitivityMathematicsfirst-order logicDiscrete mathematicsTransitive relationNEXPTIME010102 general mathematicsdecidabilityfluted fragmentSatisfiabilityDecidabilityFirst-order logicPhilosophysatisfiability010201 computation theory & mathematicssatisfabilityBoolean satisfiability problemcomplexityJournal of Symbolic Logic
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Positive Teacher Affect and Maternal Support Facilitate Adjustment After the Transition to First Grade

2016

This longitudinal study, conducted among a sample of Finnish primary-school children, examined the proposition that a single high-quality relationship (either with a teacher or a parent) can buffer against adjustment problems. Teachers rated the externalizing problems and prosocial behaviors of 378 children in Grade 1 and again in Grade 2. Relationship measures gathered in Grade 1 included teacher reports of positive affect for the child and mother reports of support for the child. The results supported our proposition by showing that for child adjustment after the transition to primary school it was critical to have at least one high-quality relationship either with a teacher or a parent. …

Longitudinal studyScreening testeducationPredictor variablesAffect (psychology)EducationDevelopmental psychologymaternal supportmental disordersDevelopmental and Educational Psychology0501 psychology and cognitive sciencesfirst gradePath analysis (statistics)Finlandsäätöteacher affect05 social sciencesBehavior change050301 educationprimary-schoolsChild developmentProsocial behaviorPsychology0503 educationSocial Sciences (miscellaneous)050104 developmental & child psychologyMerrill-Palmer Quarterly
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Behavioral and Brain Measures of Morphological Processing in Children With and Without Familial Risk for Dyslexia From Pre-school to First Grade

2021

School-age reading skills are associated with and predicted by preschool-age cognitive risk factors for dyslexia, such as deficits in phonological awareness, rapid automatized naming, letter knowledge, and verbal short-term memory. In addition, evidence exists that problems in morphological information processing could be considered a risk factor for dyslexia. In the present study, 27 children at pre-school age and the same 27 children at first grade age performed a morphological awareness task while their brain responses were measured with magnetoencephalography. Our aim was to examine how derivational morphology in Finnish language, and concomitant accuracy and reaction times are associat…

MEGlongitudinaleducationderivational morphologypre-school childrenreading developmentpitkittäistutkimusat risk for dyslexiakielellinen kehitysGeneral Earth and Planetary Sciencesdysleksiaesikoululaisetfirst-grade childrenlukihäiriötGeneral Environmental Science
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Clinical practice format for choosing a second-line disease modifying anti-rheumatic drug in early rheumatoid arthritis after failure of 6 months' fi…

2006

International audience; BACKGROUND: The objective was to develop a clinical practice format for choosing a second-line disease-modifying anti-rheumatic drug (DMARD) after a 6-month course of a first-line DMARD in patients with early RA. METHODS: A panel of 34 experts selected treatment option from various scenarios using the Thurstone pairwise method. The experts had to choose between two proposed DMARDs without proposing other options. The scenarios were obtained using the three items: DAS28, rheumatoid factor status and radiographic structural damage. A sample of 240 among 480 scenarios for each expert was taken at random. Responses given by at least 20% of the experts were considered per…

MESH: Antirheumatic AgentsMESH: Treatment FailureDiseaseReceptors Tumor Necrosis FactorEtanerceptArthritis Rheumatoid0302 clinical medicineMESH: Practice Guidelines as Topic030212 general & internal medicineTreatment Failureskin and connective tissue diseasesMESH: Immunoglobulin GMESH: Arthritis RheumatoidAnti rheumatic drugs3. Good healthClinical PracticeMESH: Methotrexate[SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal systemRheumatoid arthritisAntirheumatic AgentsPractice Guidelines as TopicDrug Therapy CombinationLeflunomidemusculoskeletal diseasesmedicine.medical_specialtyMESH: Rheumatoid FactorFirst lineMESH: Drug Administration ScheduleDrug Administration ScheduleDecision Support Techniques03 medical and health sciencesRheumatologyRheumatoid FactorDmard therapymedicineRheumatoid factorHumansIntensive care medicine030203 arthritis & rheumatologyMESH: HumansMESH: Sulfasalazinebusiness.industryMESH: Biological MarkersMESH: Decision Support TechniquesEarly rheumatoid arthritisIsoxazolesmedicine.diseaseMESH: Receptors Tumor Necrosis FactorRadiographySulfasalazineMESH: Drug Therapy CombinationMethotrexateMESH: IsoxazolesImmunoglobulin GPhysical therapybusinessBiomarkersJoint bone spine
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Performance of the First ANTARES Detector Line

2009

In this paper we report on the data recorded with the first Antares detector line. The line was deployed on the 14th of February 2006 and was connected to the readout two weeks later. Environmental data for one and a half years of running are shown. Measurements of atmospheric muons from data taken from selected runs during the first six months of operation are presented. Performance figures in terms of time residuals and angular resolution are given. Finally the angular distribution of atmospheric muons is presented and from this the depth profile of the muon intensity is derived.

MODULEPhysics::Instrumentation and DetectorsFOS: Physical sciencesAstrophysics01 natural sciencesNuclear physicsNEUTRINO TELESCOPESAngular distributionantares; deep-sea; first line; neutrino0103 physical sciencesNeutrino[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]WATERAngular resolutionNEUTRINO TELESCOPE010306 general physicsATMOSPHERIC MUONSAstroparticle physicsPhysicsMuonANTARES010308 nuclear & particles physicsAstrophysics (astro-ph)DetectorDeep-seaAstronomy and AstrophysicsTime resolutionGeodesyMUON FLUXFirst lineSINGLEFísica nuclearUNDERWATER DETECTORLine (text file)NeutrinoSYSTEM
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El patrón oro y el euro. Una reflexión a partir de la lectura de A Tract on Monetary Reform

2017

This paper makes a comparison between the gold standard and the euro through a study of Keynes’s views on the need to manage the macroeconomic situation of an industrial economy. The essay centers on Keynes’s first relevant economic work of the post World War I years, A Tract on Monetary Reform, analyzing its theoretical and practical content. The situation of monetary instability and the choice of exchange regime (to return or not to the gold standard, with the parity prior to the war) were the factors that attracted Keynes’s attention in those years. Similarities between the gold standard and the present euro system bestow a certain interest on Keynes’s ideas and on the economic discussio…

MacroeconomicsSpanish Civil WarTipos de cambioPolítica monetariaEconomicsMonetary reformSistema del euroKeynesPatrón oroGeneral Economics Econometrics and FinanceBanco centralFirst world warEconomía
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An experimental manipulation of life-history trajectories and resistance to oxidative stress

2006

Optimal investment into life-history traits depends on the environmental conditions that organisms are likely to experience during their life. Evolutionary theory tells us that optimal investment in reproduction versus maintenance is likely to shape the pattern of age-associated decline in performance, also known as aging. The currency that is traded against different vital functions is, however, still debated. Here, we took advantage of a phenotypic manipulation of individual quality in early life to explore (1) long-term consequences on life-history trajectories, and (2) the possible physiological mechanism underlying the life-history adjustments. We manipulated phenotypic quality of a co…

Male0106 biological sciencesSenescenceAgingsenescenceOffspringmedia_common.quotation_subject[SDE.MCG]Environmental Sciences/Global ChangesLongevityZoologyfree radicalsBiology010603 evolutionary biology01 natural sciences[ SDV.EE ] Life Sciences [q-bio]/Ecology environment03 medical and health sciencesGeneticsAnimalsEcology Evolution Behavior and Systematics030304 developmental biologymedia_common[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyEcologyLongevitysenescence.biology.organism_classificationFecundityBiological Evolution[SDE.ES]Environmental Sciences/Environmental and SocietyBrooddisposable-soma theory of agingOxidative Stress[ SDE.MCG ] Environmental Sciences/Global ChangesFertilityPhenotypeAging/physiology; Animals; Evolution; Female; Fertility/physiology; Finches/physiology; Longevity; Male; Oxidative Stress/physiology; PhenotypeAge at first reproductionFemaleFinchesReproductive valueReproduction[SDE.BE]Environmental Sciences/Biodiversity and EcologyGeneral Agricultural and Biological Sciencesresistance to oxidative stressTaeniopygia[ SDE.ES ] Environmental Sciences/Environmental and Societylife-table response experiment
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Retrospective study of the bone morphology in the posterior mandibular region. Evaluation of the prevalence and the degree of lingual concavity and t…

2016

Background In order to choose the appropriate implant size and to prevent complications, an oral surgeon must know the size and shape of the mandible. In the posterior mandibular region, a lingual undercut is often found and could represent a difficulty hard to manage if a lingual or buccal perforation occur. A large series of computed tomography (CT) images of the mandibular first molar was evaluated and the bone morphology, the prevalence and the degree of the lingual concavity in the first molar region were studied. Material and Methods One hundred and fifty-one computed tomography (CT) examinations of patients were retrospectively evaluated to determine anatomical variations in bone mor…

Male0206 medical engineeringPerforation (oil well)Dentistry02 engineering and technologySubmandibular fossaMandibleMandibular first molar03 medical and health sciences0302 clinical medicinestomatognathic systemPrevalenceMedicineHumansGeneral DentistryRetrospective StudiesDental ImplantsBone morphologybusiness.industryResearchDental Implantation EndosseousMandibleMandibular regionRetrospective cohort study030206 dentistry:CIENCIAS MÉDICAS [UNESCO]020601 biomedical engineeringstomatognathic diseasesIncreased riskOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleOral Surgerybusiness
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