6533b873fe1ef96bd12d59b9

RESEARCH PRODUCT

Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis : A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects

Javier SalmerónRosa Martin-mateosSalvador AugustinConrado M. Fernández-rodríguezJavier CrespoJosé Miguel RosalesDesam EscuderoJudith Gómez-camareroJoan CaballeríaMaría Jesús Pareja‐megiaHepamet RegistryRosa Maria MorillasJuan TurnesJesus M. BanalesJavier AbadPatricia AspichuetaRocío Gallego-duránRaquel LatorreLuis IbañezManuel Romero‐gomezManuel Romero-gómezJavier García-samaniegoMoisés DiagoManuel Hernández-guerraSalvador BenllochGermán SorianoÁGueda González-rodríguezJavier AmpueroJavier AmpueroRaúl J. AndradeOreste Lo IaconoRocío AllerRubén FrancésPamela EstévezFrancisco Jorquera

subject

Liver Cirrhosismedicine.medical_specialtyCirrhosisSteatosisBiopsyGastroenterologydigestive systemBallooning03 medical and health sciencesLiver disease0302 clinical medicineNon-alcoholic Fatty Liver DiseaseFatty liver diseaseInternal medicineBiopsyNonalcoholic fatty liver diseasemedicineassociated fatty liver diseaseMetabolic-associated fatty liver diseaseHumansmetabolic&#8208Longitudinal StudiesFirst episodeInflammationHepatologymedicine.diagnostic_testballooning fatty liver disease inflammation metabolic-associated fatty liver disease natural coursesteatohepatitis steatosisbusiness.industryFatty liverNatural coursesteatohepatitismedicine.diseasedigestive system diseasesLiver030220 oncology & carcinogenesis030211 gastroenterology & hepatologySteatosisSteatohepatitisbusiness

description

[Background and Aim] Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) features, which is one of the leading causes of screening failure in clinical trials. We assessed the NASH distribution and its components across the fibrosis stages and their impact on the prognosis and their relationship with the concept of metabolic-associated fatty liver disease (MAFLD).

10.1111/liv.14898https://ddd.uab.cat/record/270312