Search results for "fluids"
showing 10 items of 1936 documents
A neoepitope generated by an FLT3 internal tandem duplication (FLT3-ITD) is recognized by leukemia-reactive autologous CD8+ T cells.
2006
Abstract The FLT3 receptor tyrosine kinase is expressed in more than 90% of acute myelogeneous leukemias (AMLs), up to 30% of which carry an internal tandem duplication (ITD) within the FLT3 gene. Although varying duplication sites exist, most FLT3-ITDs affect a single protein domain. We analyzed the FLT3-ITD of an AML patient for encoding HLA class I–restricted immunogenic peptides. One of the tested peptides (YVDFREYEYY) induced in vitro autologous T-cell responses restricted by HLA-A*0101 that were also detectable ex vivo. These peptide-reactive T cells recognized targets transfected with the patient's FLT3-ITD, but not wild-type FLT3, and recognized the patient's AML cells. Our results …
Active and inactive quarantine in epidemic spreading on adaptive activity-driven networks
2020
We consider an epidemic process on adaptive activity-driven temporal networks, with adaptive behaviour modelled as a change in activity and attractiveness due to infection. By using a mean-field approach, we derive an analytical estimate of the epidemic threshold for SIS and SIR epidemic models for a general adaptive strategy, which strongly depends on the correlations between activity and attractiveness in the susceptible and infected states. We focus on strong social distancing, implementing two types of quarantine inspired by recent real case studies: an active quarantine, in which the population compensates the loss of links rewiring the ineffective connections towards non-quarantining …
RationalizeRoots: Software Package for the Rationalization of Square Roots
2019
The computation of Feynman integrals often involves square roots. One way to obtain a solution in terms of multiple polylogarithms is to rationalize these square roots by a suitable variable change. We present a program that can be used to find such transformations. After an introduction to the theoretical background, we explain in detail how to use the program in practice.
Upperbounds on the probability of finding marked connected components using quantum walks
2019
Quantum walk search may exhibit phenomena beyond the intuition from a conventional random walk theory. One of such examples is exceptional configuration phenomenon -- it appears that it may be much harder to find any of two or more marked vertices, that if only one of them is marked. In this paper, we analyze the probability of finding any of marked vertices in such scenarios and prove upper bounds for various sets of marked vertices. We apply the upper bounds to large collection of graphs and show that the quantum search may be slow even when taking real-world networks.
Transient dynamics of pulse-driven memristors in the presence of a stable fixed point
2019
Abstract Some memristors are quite interesting from the point of view of dynamical systems. When driven by narrow pulses of alternating polarities, their dynamics has a stable fixed point, which may be useful for future applications. We study the transient dynamics of two types of memristors characterized by a stable fixed point using a time-averaged evolution equation. Time-averaged trajectories of the Biolek window function memristor and resistor-threshold type memristor circuit (an effective memristor) are determined analytically, and the times of relaxation to the stable fixed point are found. Our analytical results are in perfect agreement with the results of numerical simulations.
Parity Oblivious d-Level Random Access Codes and Class of Noncontextuality Inequalities
2016
One of the fundamental results in quantum foundations is the Kochen-Specker no-go theorem. For the quantum theory, the no-go theorem excludes the possibility of a class of hidden variable models where value attribution is context independent. Recently, the notion of contextuality has been generalized for different operational procedures and it has been shown that preparation contextuality of mixed quantum states can be a useful resource in an information-processing task called parity-oblivious multiplexing. Here, we introduce a new class of information processing tasks, namely d-level parity oblivious random access codes and obtain bounds on the success probabilities of performing such task…
Fractional generalized cumulative entropy and its dynamic version
2021
Following the theory of information measures based on the cumulative distribution function, we propose the fractional generalized cumulative entropy, and its dynamic version. These entropies are particularly suitable to deal with distributions satisfying the proportional reversed hazard model. We study the connection with fractional integrals, and some bounds and comparisons based on stochastic orderings, that allow to show that the proposed measure is actually a variability measure. The investigation also involves various notions of reliability theory, since the considered dynamic measure is a suitable extension of the mean inactivity time. We also introduce the empirical generalized fract…
Multiscale Information Decomposition: Exact Computation for Multivariate Gaussian Processes
2017
Exploiting the theory of state space models, we derive the exact expressions of the information transfer, as well as redundant and synergistic transfer, for coupled Gaussian processes observed at multiple temporal scales. All of the terms, constituting the frameworks known as interaction information decomposition and partial information decomposition, can thus be analytically obtained for different time scales from the parameters of the VAR model that fits the processes. We report the application of the proposed methodology firstly to benchmark Gaussian systems, showing that this class of systems may generate patterns of information decomposition characterized by prevalently redundant or sy…
Local Granger causality
2021
Granger causality is a statistical notion of causal influence based on prediction via vector autoregression. For Gaussian variables it is equivalent to transfer entropy, an information-theoretic measure of time-directed information transfer between jointly dependent processes. We exploit such equivalence and calculate exactly the 'local Granger causality', i.e. the profile of the information transfer at each discrete time point in Gaussian processes; in this frame Granger causality is the average of its local version. Our approach offers a robust and computationally fast method to follow the information transfer along the time history of linear stochastic processes, as well as of nonlinear …
The network of global corporate control.
2011
The structure of the control network of transnational corporations affects global market competition and financial stability. So far, only small national samples were studied and there was no appropriate methodology to assess control globally. We present the first investigation of the architecture of the international ownership network, along with the computation of the control held by each global player. We find that transnational corporations form a giant bow-tie structure and that a large portion of control flows to a small tightly-knit core of financial institutions. This core can be seen as an economic “super-entity” that raises new important issues both for researchers and policy make…