Search results for "focal"

Porous Gelatin Hydrogels:  2. In Vitro Cell Interaction Study

2007

We report on the feasibility of applying porous gelatin hydrogels, prepared by a novel and controlled cryogenic treatment, as cell-interactive scaffolds for tissue engineering applications. Despite the large number of publications on gelatin as a biomaterial, a detailed study of screening a limited number of gelatin scaffolds for their interaction with a panel of human cells has, to the best of our knowledge, not yet been published. In the present work, we have evaluated two types of porous gelatin scaffolds that differ in their pore geometry and pore size. Type I hydrogels contained top-to-bottom transverse channels (i.e. cones) with a decreasing diameter from the top (330 microm) to the b…

Subjective photic phenomena with refractive multifocal and monofocal intraocular lenses. results of a multicenter questionnaire.

2001

Abstract Purpose To compare the incidence and severity of photic phenomena after the implantation of the Array® (Allergan) refractive multifocal intraocular lens (MIOL) and a monofocal IOL. Setting Multicenter study at Kiel, Mainz, Karlsruhe, and Bremerhaven, Germany. Methods The study comprised 231 randomly selected patients from 4 study centers. The patients had had uneventful phacoemulsification with implantation of a refractive MIOL (n = 138) or a monofocal IOL (n = 93). By questionnaire, patients were asked whether they experienced light sensations postoperatively (light streaks, halos, flare, flashes, or glare) that had not been noticed preoperatively. Additional questions evaluated w…

Opto-mechanical artificial eye with accommodative ability.

2015

The purpose of this study was to describe the design and characterization of a new opto-mechanical artificial eye (OMAE) with accommodative ability. The OMAE design is based on a second-pass configuration where a small source of light is used at the artificial retina plane. A lens whose focal length can be changed electronically was used to add the accommodation capability. The changes in the OMAE's aberrations with the lens focal length, which effectively changes the accommodative state of the OMAE, were measured with a commercial aberrometer. Changes in power and aberrations with room temperature were also measured. The OMAE's higher-order aberrations (HOAs) were similar to the ones of th…

Modulation transfer function in refractive-diffractive multifocal intraocular lenses in vitro

2007

Purpose: The optical quality of two types of multifocal, hybrid refractive-diffractive, intraocular lenses (IOL) is analyzed in vitro. Following the EN-ISO international standard, the IOLs’ modulation transfer functions (MTF) are determined for both distance and near vision. The behaviour of these curves when the pupil size varies is studied. Methods: The IOLs analyzed were: AcrySoft ResTor SN60D3 (Alcon) and Tecnis ZM900 (AMO). The MTF was calculated from the cross line-spread function recorded with the OPAL Vector System (Image Science Ltd. Oxford) by using fast Fourier transform techniques. The artificial eye model used simulates in vivo conditions of the anterior chamber including an ar…

Multifokale Intraokularlinsen

2001

Modern cataract surgery has developed tremendously during the past 10-15 years. Improved surgical techniques, as well as improved implant materials and designs, have enlarged patient profiles and indications for cataract surgery. This also created much higher expectations from the patients' site. The loss of accommodation is loss of quality of life for presbyopic and especially young pseudophakic patients. Therefore cataract surgery with multifocal IOL implantation is not only of academic interest, but reflects demands and expectations of our patients. Multifocal IOLs have been implanted since 1986, starting with 2-3 zone refractive and diffractive designs. Due to surgical techniques of tha…

Interactions of virus proteins within the host cell

2014

Hydrophobin (HFBI): a potential fusion partner for one-step purification of recombinant proteins from insect cells

2008

Hydrophobins play an important role in binding and assembly of fungal surface structures as well as in medium-air interactions. These, hydrophobic properties provide interesting possibilities when purification of macromolecules is concerned. In aqueous micellar two-phase systems, based on surfactants, the water soluble hydrophobins are concentrated inside micellar structures and, thus, distributed to defined aqueous phases. This, one-step purification is attractive particularly when large-scale production of recombinant proteins is concerned. In the present study the hydrophobin HFBI of Trichoderma reesei was expressed as an N-terminal fusion with chicken avidin in baculovirus infected inse…

Visual and refractive outcomes in hyperopic pseudophakic patients implanted with a trifocal intraocular lens

2019

José F Alfonso,1,2 Andrés Fernández-Vega-Cueto,1 Belén Alfonso-Bartolozzi,1 Ignacio Rodríguez-Uña,1 Robert Montés-Micó3 1Corneal and Lens Surgery Department, Fernández-Vega Ophthalmological Institute, Oviedo, Spain; 2Surgery Department, School of Medicine, University of Oviedo, Oviedo, Spain; 3Optics and Optometry and Vision Sciences Department, Faculty of Physics, University of Valencia, Valencia, SpainCorrespondence: José F AlfonsoInstituto Oftalmológico Fernández-Vega, Avda. Dres. Fernández-Vega 114, Oviedo 33012, SpainTel +34 985 245533Fax +34 98…

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Mode…

2018

The enhanced permeability and retention (EPR) effect is the only described mechanism enabling nanoparticles (NPs) flowing in blood to reach tumors by a passive targeting mechanism. Here, using the transparent zebrafish model infected with Mycobacterium marinum we show that an EPR-like process also occurs allowing different types of NPs to extravasate from the vasculature to reach granulomas that assemble during tuberculosis (TB) infection. PEGylated liposomes and other NP types cross endothelial barriers near infection sites within minutes after injection and accumulate close to granulomas. Although similar to 100 and 190 nm NPs concentrated most in granulomas, even similar to 700 nm liposo…

Metaliterārais vēstījums romānā „Džentelmeņa Tristrama Šendija dzīve un uzskati” un tā ekranizācija

2015

Maģistra darbā „Metaliterārais vēstījums romānā Džentlmeņa Tristrama Šendija dzīve un uzskati un tā ekranizācijā” ir veikts Lorensa Sterna literārā pirmavota un Maikla Vinterbotoma adaptācijas Tristrams Šendijs: stāsts par gaili un bulli metanaratīvu salīdzinājums. Darba mērķis ir atainot filmas un romāna metanaratīva aspektus un noteikt paņēmienus, kādi ir izmantoti metanaratīvu tekstā adaptējot romāna ekranizācijā. Teorētiskajā daļā ir sniegts izskaidrojums tādiem konceptiem kā metaliterārais un filmu naratīvs, fokalizācija, metaizācijas apstākļi, kā arī metatekstualitātes un metadaptāciju aspekti, kuri ir aktuāli analizējot Tristramu Šendiju. Empīriskajā daļā ir sniegtas atbildes uz pētī…