Search results for "goals"

showing 10 items of 643 documents

Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial

2015

KRAS mutation has been reported as a marker of radio-resistance in rectal cancer and unfavourable outcome in both colon and rectal cancer. This study suggests that a single-nucleotide polymorphism of the KRAS gene (LCS-6 variant) may predict response to neoadjuvant treatment and mitigate the poor prognosis associated with KRAS mutation in locally advanced rectal cancer.

MaleOncologyOrganoplatinum CompoundsColorectal cancermedicine.medical_treatmentLET-7 MICRORNA-BINDINGCetuximabmedicine.disease_causeCOLORECTAL-CANCER3'-UNTRANSLATED REGION0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsRectal cancerNeoadjuvant therapySingle-nucleotide polymorphism0303 health sciencesCetuximabCOLON-CANCERHazard ratioCAPOX RegimenChemoradiotherapyHematologysingle-nucleotide polymorphismMiddle AgedCombined Modality TherapyNeoadjuvant TherapyBINDING SITE POLYMORPHISM3. Good healthOxaliplatinLet-7Oncology030220 oncology & carcinogenesis5-FLUOROURACIL/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleKRASLife Sciences & Biomedicinemedicine.drugAdultGenetic Markersmedicine.medical_specialtyGenotypeLCS-6 KRAS variantPolymorphism Single NucleotideDisease-Free SurvivalCLINICAL-TRIALProto-Oncogene Proteins p21(ras)03 medical and health sciencesSDG 3 - Good Health and Well-beinglet-7Internal medicineGastrointestinal TumorsBiomarkers TumorKRASmedicineHumansOncology & CarcinogenesisProgression-free survivalrectal cancerneoplasmsCapecitabineAged030304 developmental biologyCancer och onkologiScience & TechnologyRectal Neoplasmsbusiness.industryOriginal Articlesmedicine.diseasedigestive system diseasesMicroRNAsCancer and Oncologybusiness1112 Oncology And CarcinogenesisChemoradiotherapyRASAnnals of Oncology
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Changes in 10-12 year old's fruit and vegetable intake in Norway from 2001 to 2008 in relation to gender and socioeconomic status - a comparison of t…

2011

Published version of an article in the journal: International Journal of Behavioral Nutrition and Physical Activity. Also available from the publisher BMC: http://dx.doi.org/10.1186/1479-5868-8-108. Open Access BACKGROUND:Norwegian children and adolescents eat less than half of the recommended 5 portions of fruit and vegetables (FV) per day. Gender and socioeconomic disparities in FV consumption shows that boys and children of lower socioeconomic status (SES) eat less FV than girls and high SES children. We also know that accessibility and preferences has been identified as two important determinants of FV intake. The objectives of this study were to compare FV intake among Norwegian 6th an…

MaleParentsGerontologyAdolescentCross-sectional studyMedicine (miscellaneous)Physical Therapy Sports Therapy and RehabilitationClinical nutritionNorwegianSocial classDiet SurveysFruit and vegetable intakeVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811Food Supplysocioeconomic statusSex FactorschildrenVegetablesgenderHumansChildSocioeconomic statuslcsh:RC620-627time trendsNutrition and DieteticsFood frequencyNorwayResearchlcsh:Public aspects of medicinelcsh:RA1-1270Feeding BehaviorBaseline surveySDG 10 - Reduced Inequalitieslanguage.human_languageDietPeer reviewlcsh:Nutritional diseases. Deficiency diseasesCross-Sectional StudiesSocial ClassFruitlanguage/dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalitiesEducational StatusFemaleEnergy IntakePsychologyDemographyInternational Journal of Behavioral Nutrition and Physical Activity
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Longitudinal heritability of childhood aggression

2016

The genetic and environmental contributions to the variation and longitudinal stability in childhood aggressive behavior were assessed in two large twin cohorts, the Netherlands Twin Register (NTR), and the Twins Early Development Study (TEDS; United Kingdom). In NTR, maternal ratings on aggression from the Child Behavior Checklist (CBCL) were available for 10,765 twin pairs at age 7, for 8,557 twin pairs at age 9/10, and for 7,176 twin pairs at age 12. In TEDS, parental ratings of conduct disorder from the Strength and Difficulty Questionnaire (SDQ) were available for 6,897 twin pairs at age 7, for 3,028 twin pairs at age 9 and for 5,716 twin pairs at age 12. In both studies, stability and…

MaleParentsNetherlands Twin Register (NTR)0301 basic medicinePersonality InventoryPoison controlCBCLheritability0302 clinical medicineLongitudinal StudiesChildChild Behavior Checklistta515Genetics (clinical)NetherlandsaggressionAge Factorsta3142Justice and Strong InstitutionsPsychiatry and Mental healthConduct disorderFemalePersonality Assessment Inventorymedicine.symptomPsychologyTwins Early Development StudySDG 16 - PeaceAdolescentlongitudinalEnvironment03 medical and health sciencesCellular and Molecular NeuroscienceSex FactorsDiseases in Twins/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_medicineHumansGenetic Association StudiesAggressionta1184SDG 16 - Peace Justice and Strong InstitutionsstabilityHeritabilitymedicine.diseasegenetic architecture/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsUnited Kingdomta3124030104 developmental biologyGene-Environment Interaction030217 neurology & neurosurgeryDemographyAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics
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Clinicopathological evaluation of 164 dental follicles and dentigerous cysts with emphasis on the presence of odontogenic epithelium in the connectiv…

2012

Objectives: Some ameloblastomas presumably originate from odontogenic epithelium within the connective tissue of dental follicles and dentigerous cysts. Therefore, it would seem reasonable to discuss as whether odontogenic epithelium proliferations, frankly displaying ameloblastomatous features (“focal ameloblastoma”), should be considered as an “early” ameloblastoma. Study Design: Histopathological reports from 164 dental follicles and dentigerous cysts from the Department of Oral and Maxillofacial Surgery/Oral Pathology of the VU Free University medical center in Amsterdam, The Ne-therlands, were reviewed. Histopathological slides from 39 cases reporting the presence of odontogenic epithe…

MalePathologymedicine.medical_specialtyDentigerous CystConnective tissueOdontologíaEpitheliumAmeloblastomaYoung AdultSDG 3 - Good Health and Well-beingDental SacOral and maxillofacial pathologymedicineHumansAmeloblastomaGeneral DentistryDental folliclebusiness.industryDental Sac:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludEpitheliumDentigerous cystmedicine.anatomical_structureOtorhinolaryngologyConnective TissueUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgery/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleResearch-ArticleSurgeryOral Surgerybusiness
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Longitudinal associations of energy balance-related behaviours and cross-sectional associations of clusters and body mass index in Norwegian adolesce…

2010

AbstractBackgroundInsight into the role of energy balance-related behaviours (EBRB) is of great importance when it comes to prevention of weight gain and design of interventions tailored to target these behaviours.ObjectivesFirst, the present study examines the longitudinal association of four EBRB in Norwegian adolescents. Second, it aims to examine whether clusters of EBRB are cross-sectionally associated with being overweight.DesignThe present study is part of the ‘Fruits and Vegetables Make the Marks’ project. The study sample consists of twenty control schools in two Norwegian counties.MethodsSurvey questionnaires were completed by 884 pupils with an average age at baseline, September …

MalePediatricsmedicine.medical_specialtyAdolescentHealth BehaviorPsychological interventionMedicine (miscellaneous)NorwegianMotor ActivityOverweightBody Mass IndexOddsSDG 3 - Good Health and Well-beingSurveys and QuestionnairesEnvironmental healthmedicineHumansLongitudinal StudiesObesityExerciseLife StyleNutrition and DieteticsSnackingComputersNorwayPublic Health Environmental and Occupational HealthFeeding BehaviorOverweightmedicine.diseaseHealth SurveysObesitylanguage.human_languageDietCross-Sectional StudiesAdolescent Behaviorlanguage/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleTelevisionSedentary Behaviormedicine.symptomEnergy MetabolismPsychologyWeight gainBody mass indexPublic Health Nutrition
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Determinants of a regular intake of a nutritionally balanced school lunch among 10-17-year-old schoolchildren with special reference to sense of cohe…

2015

Background Free nutritionally balanced school lunches are offered to all schoolchildren in basic education in Finland in each school day. Having school lunch on a regular basis has been found to reflect overall eating patterns. However, skipping part of or even the entire lunch is common. The present study investigated the determinants of the regular consumption of a nutritionally balanced school lunch among schoolchildren, with special reference to the role of sense of coherence (SOC). Methods In total, 887 children (457 girls and 424 boys), aged 10–17 years from three municipalities in Eastern Finland, filled in a web-based questionnaire in class during a school day and reported eating pa…

MalePediatricsmedicine.medical_specialtyAdolescentSense of Coherencemedia_common.quotation_subjecteducationMedicine (miscellaneous)sense of coherenceLogistic regressionEating patternsEatingPerceptionSurveys and QuestionnairesBasic educationBody ImageMedicineHumansFamilyChildschool lunchLife StyleFinlandmedia_commonConsumption (economics)MealInternetNutrition and DieteticsChi-Square DistributionSchoolsbusiness.industrydigestive oral and skin physiologyBody Weightschoolchildrenta3142Feeding Behavior/dk/atira/pure/sustainabledevelopmentgoals/quality_educationBody HeightTest (assessment)Logistic ModelsLunchScale (social sciences)FemalebusinessSDG 4 - Quality EducationDemographySense of coherenceJournal of human nutrition and dietetics : the official journal of the British Dietetic Association
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Validation of the Multicultural Personality Questionnaire Short Form (MPQ-SF) for use in the context of international education

2020

The Multicultural Personality Questionnaire (MPQ) is one of the most widely used instruments for measuring individuals’ intercultural competences. The original version consists of 91 items, divided into five subscales, and has been shown to predict attitudes, behavior, and outcomes in a variety of intercultural contexts. Recently, a 40-item short form of the MPQ was developed (MPQ-SF), which may be particularly useful in settings in which time or survey space are limited, or where respondent drop-out is likely to occur. For example, the MPQ-SF would be a valuable tool for assessing longitudinal development of multicultural personality traits in training or educational settings. A prerequisi…

MalePersonality TestsLongitudinal studyPsychometricsPsychological AdjustmentSciencemedia_common.quotation_subjectCultureEmotionsApplied psychologyInternational Educational ExchangeSocial Sciences050109 social psychologyContext (language use)Young AdultInternational educationSociologySurveys and QuestionnairesCross-Cultural Studies0502 economics and businessHumansPsychologyPersonality0501 psychology and cognitive sciencesMeasurement invarianceLongitudinal StudiesBig Five personality traitsStudentsCompetence (human resources)media_commonPersonality TraitsMeasurementMultidisciplinaryQ05 social sciencesRBiology and Life SciencesCultural Diversity/dk/atira/pure/sustainabledevelopmentgoals/quality_educationRespondentMedicineEngineering and TechnologyFemalePsychologySDG 4 - Quality Education050203 business & managementPersonalityResearch ArticlePLOS ONE
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Auditory cortex reflects goal-directed movement but is not necessary for behavioral adaptation in sound-cued reward tracking

2020

Mounting evidence suggests that the role of sensory cortices in perceptual decision making goes beyond the mere representation of the discriminative stimuli and additionally involves the representation of nonsensory variables such as reward expectation. However, the relevance of these representations for behavior is not clear. To address this issue, we trained rats to discriminate sounds in a single-interval forced-choice task and then confronted the animals with unsignaled blockwise changes of reward probabilities. We found that unequal reward probabilities for the two choice options led to substantial shifts in response bias without concomitant reduction in stimulus discrimination. Althou…

MalePhysiologyMovementPrefrontal CortexSensory systemStimulus (physiology)Auditory cortexChoice BehaviorDiscrimination PsychologicalRewardAdaptation PsychologicalmedicineAnimalsRats Long-EvansSensory cortexPrefrontal cortexAuditory CortexAdaptive behaviorGeneral NeuroscienceResponse biasAnticipationRatsmedicine.anatomical_structureAuditory PerceptionCuesPsychologyGoalsNeuroscienceJournal of Neurophysiology
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Resonance of cortico-cortical connections of the motor system with the observation of goal directed grasping movements

2010

Goal directed movements require the activation of parietal, premotor and primary motor areas. In monkeys, neurons of these areas become active also during the observation of movements performed by others, especially for coding the goal of the action (mirror system). Using bifocal transcranial magnetic stimulation (TMS) in healthy subjects, we tested whether the observation of goal directed reach to grasp actions may lead to specific changes in the short-latency connections linking key areas of the mirror system, such as the anterior intraparietal cortex (AIP) and the ventral premotor cortex (PMv), with the primary motor cortex (M1). We found that AIP-M1 and PMv-M1 cortico-cortical interacti…

MalePremotor cortexmedicine.medical_treatmentObservationParietal cortexGoalBehavioral NeuroscienceCortex (anatomy)Neural PathwaysEvoked PotentialsMirror neuronCerebral CortexConnectivityBrain MappingHand StrengthMIRROR NEURONSBody movementSkeletalTranscranial Magnetic Stimulationmedicine.anatomical_structureMotorMuscleFemaleSettore MED/26 - NeurologiaPrimary motor cortexPsychologyGoalsHumanAdultConnectivity; Observation; Parietal cortex; Premotor cortex; Transcranial magnetic stimulation;Cognitive NeuroscienceMovementGoals; Movement; Muscle Skeletal; Male; Young Adult; Electromyography; Female; Evoked Potentials Motor; Cerebral Cortex; Humans; Photic Stimulation; Psychomotor Performance; Observation; Hand Strength; Neural Pathways; Transcranial Magnetic Stimulation; Brain Mapping; AdultPosterior parietal cortexExperimental and Cognitive PsychologyConnectivity; Observation; Parietal cortex; Premotor cortex; Transcranial magnetic stimulationNOPremotor cortexNeural PathwayYoung AdultMotor systemmedicineHumansMuscle SkeletalSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaElectromyographyEvoked Potentials MotorTranscranial magnetic stimulationGoals; Young Adult; Humans; Electromyography; Observation; Movement; Muscle Skeletal; Cerebral Cortex; Photic Stimulation; Brain Mapping; Evoked Potentials Motor; Adult; Neural Pathways; Hand Strength; Psychomotor Performance; Transcranial Magnetic Stimulation; Female; MaleTMSNeurosciencePhotic StimulationPsychomotor Performance
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Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction.

2015

Background: The aims of the study were 1) to evaluate the incidence and types of postoperative complications after ablative oral cancer surgery with primary free flap reconstruction and 2) identify prognostic variables for postoperative complications. Material and Methods: Desired data was retrieved from a computer database at the department of Oral and Maxillofacial Department, Queen Elisabeth hospital Birmingham, United Kingdom, between June 2007 and October 2012. Logistic regression was used to study relationships between preoperative variables and postoperative outcomes. Results: The study population consisted 184 patients, comprising 189 composite resections with reconstruction. Compli…

MalePrognostic variablemedicine.medical_specialtyOdontologíaFree flapLogistic regressionFree Tissue FlapsPostoperative ComplicationsSDG 3 - Good Health and Well-beingAblative caseMedicineHumansGeneral DentistryRetrospective StudiesMouth neoplasmbusiness.industryIncidence (epidemiology)IncidenceResearchRetrospective cohort studyLength of StayMiddle Aged:CIENCIAS MÉDICAS [UNESCO]PrognosisCiencias de la saludSurgeryOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASMicrovessels/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPopulation studySurgeryFemaleMouth NeoplasmsOral SurgerybusinessMedicina oral, patologia oral y cirugia bucal
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