Search results for "grape"
showing 10 items of 291 documents
Anti-Atherosclerotic Effect of a Polyphenol-Rich Ingredient, Oleactiv
2018
The development of nutraceutical ingredients has risen as a nutritional solution for health prevention. This study evaluated the effects of Oleactiv®, an ingredient developed for the prevention of atherogenesis, in hypercholesterolemic hamsters. Oleactiv® is a polyphenol-rich ingredient obtained from artichoke, olive and grape extracts as part of fruit and vegetables commonly consumed within the Mediterranean diet. A total of 21 Golden Syrian hamsters were divided into three groups. The standard group (STD) was fed a normolipidemic diet for 12 weeks, while the control group (CTRL) and Oleactiv® goup (OLE) were fed a high-fat diet. After sacrifice, the aortic fatty streak area (AFSA), plasma…
Grape seed and skin extract reduces pancreas lipotoxicity, oxidative stress and inflammation in high fat diet fed rats.
2016
IF 2.326; International audience; Obesity is related to an elevated risk of diabetes and the mechanisms whereby fat adversely affects the pancreas are poorly understood. We studied the effect of a high fat diet (HFD) on pancreas steatosis, oxidative stress and inflammation as well as the putative protection afforded by grape seed and skin extract (GSSE). HFD induced body weight gain, without affecting insulinemia, nor glycemia and dropped adiponectemia. HFD also provoked the ectopic deposition of cholesterol and triglyceride, and an oxidative stress characterized by increased lipoperoxidation and carbonylation, inhibition of antioxidant enzyme activities such as CAT, GPx and SOD, depletion …
Modelling intestinal absorption of salbutamol sulphate in rats
2005
The objective was to develop a semiphysiological population pharmacokinetic model that describes the complex salbutamol sulphate absorption in rat small intestine. In situ techniques were used to characterize the salbutamol sulphate absorption at different concentrations (range: 0.15-18 mM). Salbutamol sulphate at concentration of 0.29 mM was administered in presence of verapamil (10 and 20 mM), grapefruit juice and sodium azide (NaN3) (0.3, 3 and 6 mM). Different pharmacokinetic models were fitted to the dataset using NONMEM. Parametric and non-parametric bootstrap analyses were employed as internal model evaluation techniques. The validated model suggested instantaneous equilibrium betwee…
Broncalt®, class II medical device, in patients with chronic upper airways disease: a survey in clinical practice
2019
Inflammation and infection are common pathogenic mechanisms involved in many otorhinolaryngological (ORL) chronic diseases. Broncalt® is a class II Medical Device containing: thermal water (Medesano, PR, Italy), hyaluronic acid, and grapefruit seed extract. It could exert a safe and effective anti-inflammatory, washing, and antimicrobial activity by virtue of these components. Therefore, the aim of the current survey, conducted in clinical practice of 84 Italian ORL centers, was to evaluate its safety and efficacy in the treatment of patients with chronic upper airways disease. The 1,817 (958 males, mean age 49 years) patients were evaluated at baseline (T0) and after one (T1) and two (T2) …
Broncalt®, class II medical device, in patients with chronic relapsed upper airways disease: a survey in clinical practice.
2019
Inflammation and infection are common pathogenic mechanisms involved in many otorhinolaryngological (ORL) chronic diseases. Broncalt® is a class II Medical Device containing: thermal water (Medesano, PR, Italy), hyaluronic acid, and grapefruit seed extract. It could exert a safe and effective anti-inflammatory, washing, and antimicrobial activity by virtue of these components. Therefore, the aim of the current survey, conducted in clinical practice of 84 Italian ORL centers, was to evaluate its safety and efficacy in the treatment of patients with chronic upper airways disease. The 1,817 (958 males, mean age 49 years) patients were evaluated at baseline (T0) and after one (T1) and two (T2) …
New insights into Early Celtic consumption practices: Organic residue analyses of local and imported pottery from Vix-Mont Lassois
2019
The rich Mediterranean imports found in Early Celtic princely sites (7th-5th cent. BC) in Southwestern Germany, Switzerland and Eastern France have long been the focus of archaeological and public interest. Consumption practices, particularly in the context of feasting, played a major role in Early Celtic life and imported ceramic vessels have consequently been interpreted as an attempt by the elite to imitate Mediterranean wine feasting. Here we present the first scientific study carried out to elucidate the use of Mediterranean imports in Early Celtic Central Europe and their local ceramic counterparts through organic residue analyses of 99 vessels from Vix-Mont Lassois, a key Early Celti…
Eddy covariance and sap flow measurement of energy and mass exchange of woody crops in a Mediterranean environment
2012
Evapotranspiration estimation by micrometeorological techniques through the assessment of mass and energy exchanges in the soil-plant-atmosphere continuum (SPAC) is a very active research area, involving both well-known and novel measurement techniques. A crucial aspect in validating experimental results is the integration of independent measurements of mass and energy exchanges in the SPAC. To this aim, the development and validation of an integrated approach in major tree crop species, involving different independent techniques, are presented. Eddy covariance estimates of ET fluxes were compared to up-scaled sap flow measurements in olive, orange and grapevine, three important Mediterrane…
Influence des facteurs naturels sur la maturation du raisin, en 1979, à Pomerol et Saint-Emilion
1981
<p style="text-align: justify;">Les vignobles de Pomerol et Saint-Emilion sont implantés sur des sols dérivant de roches-mères variées; ils produisent des vins de haute qualité mais différents suivant leur origine géologique.</p><p style="text-align: justify;">Dans les meilleurs crus, nous avons pu vérifier que les variations mésoclimatiques sont très faibles et ont peu d'influence sur les caractères des vins. Par contre, en 1979, une relation a été mise en évidence entre les conditions de l'alimentation en eau de la vigne (étroitement liées aux propriétés physiques des sols) et la constitution des raisins à maturité (<em>V. vinifera</em> var. Merlot noir).<…
DETERMINATION OF THE OPTIMAL MOMENT OF HARVESTING FOR CABERNET SAUVIGNON AND MERLOT GRAPES IN DRĂGĂŞANI VINEYARD
2011
This paper presents an analysis of the main characteristics of black grapes during ripening and determining the optimum moment to harvest the grapes in the vineyard Drăgăşani. Monitoring process of maturation of the grapes has been done on the varieties of grapes for red wines Cabernet Sauvignon and Merlot from Drăgăşani vineyard.
Epidemiological investigations and molecular characterization of ‘candidatus phytoplasma solani’ in grapevines, weeds, vectors and putative vectors i…
2020
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