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showing 10 items of 19225 documents

AB0210 Quality of Life Indexes in Patients with Very Early Rheumatoid Arthritis (VERA): A Two Center Subgroup Analysis from The Adapthera Cohort: Tab…

2016

Background The significance of early diagnosis and early therapy initiation in patients with RA is tremendous. ADAPTHERA is a state wide rheumatology network based in Rhineland-Palatinate, Germany. ADAPTHERA aims to improve RA prognosis and quality of patients` life by reducing the time-to-RA-diagnosis. While there have been a lot of studies regarding quality of life in patients with established RA 1,2 , adequate data concerning very early rheumatoid arthritis (VERA) (disease duration Objectives To study quality of life in VERA patients and to investigate its associations with various RA associated clinical and laboratory parameters. Methods In a two center subgroup analysis from the ADAPTH…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryVisual analogue scaleImmunologySubgroup analysisGeneral Biochemistry Genetics and Molecular BiologyRheumatologyRheumatologyQuality of lifeInternal medicineErythrocyte sedimentation rateCohortmedicinePhysical therapyImmunology and AllergyRheumatoid factorFunctional abilitybusinessAnnals of the Rheumatic Diseases
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Direct oral anticoagulants for the treatment of pulmonary embolism in patients with renal impairment.

2021

Pulmonary embolism (PE) is associated with adverse outcomes and substantial morbidity and mortality. Patients with PE often have renal impairment because of shared risk factors and close links between the renal and cardiovascular systems. Furthermore, patients with PE and renal impairment are at increased risk of recurrent thrombosis. Therefore, anticoagulation is crucial to treat the acute event, prevent recurrent venous thromboembolism (VTE), and optimize patient outcomes. However, when treated with an anticoagulant, patients with renal impairment also have an elevated risk of bleeding. Direct oral anticoagulants (DOACs) are the first-choice treatment for acute VTE in eligible patients. H…

medicine.medical_specialtymedicine.drug_classAdministration OralHemorrhage030204 cardiovascular system & hematologyurologic and male genital diseases03 medical and health sciences0302 clinical medicineRisk FactorsmedicineHumansIn patientRecurrent thrombosisPatient groupIntensive care medicinebusiness.industryAnticoagulantAnticoagulantsHematologyVenous Thromboembolismmedicine.diseasePulmonary embolismIncreased risk030220 oncology & carcinogenesisRenal physiologybusinessPulmonary EmbolismVenous thromboembolismThrombosis research
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A New Routine for Analyzing Brief Symptom Inventory Profiles in Chronic Pain Patients to Evaluate Psychological Comorbidity

2021

Question: Comorbidity, i.e., additional psychological distress in patients already suffering from chronic somatic diseases (e.g., orthopedic conditions) is of growing importance. The quality of analyzing and interpreting the often used Brief Symptom Inventory (BSI) used with orthopedic patients should improve by employing a new “case definition” of four groups (instead of two) of differentially psychologically distressed patients instead of two groups as before.Methods: Four groups with the different psychological distress definitions of “no,” “mild,” “remarkable,” and “severe” were to be analyzed from a group of 639 orthopedic patients in inpatient rehabilitation clinics. The BSI is transf…

medicine.medical_specialtymedicine.medical_treatmentChronic painPsychological interventionPsychological distressorthopedic patientsBSImedicine.diseaseComorbidityBF1-990Distressnew case definitionpsychological distressIntervention (counseling)Orthopedic surgerymedicinePhysical therapyPsychologyfour groupsPsychologyGeneral PsychologyCrisis interventionOriginal ResearchFrontiers in Psychology
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Group psychoeducation with relaxation for severe fear of childbirth improves maternal adjustment and childbirth experience – a randomised controlled …

2014

Previous studies on the treatment of women with fear of childbirth have focused on the delivery mode. Women with fear of childbirth often suffer from anxiety and/or depression, and treatment therefore also needs to target postnatal psychological well-being and the early mother-infant relationship.Three hundred and seventy-one nulliparous women out of 4575 scored ≥100 in prospective screening (Wijma Delivery Expectancy Questionnaire, W-DEQ-A), indicating severe fear of childbirth. These women were randomised to psychoeducative group intervention with relaxation (n = 131; six sessions during pregnancy, one postnatal) or to conventional care (n = 240) by community nurses (referral if necessary…

medicine.medical_specialtymedicine.medical_treatmentMothersRelaxation TherapyPatient Education as TopicPregnancySurveys and QuestionnairesAdaptation PsychologicalPsychoeducationmedicineHumansChildbirthPsychiatryta515Pregnancybusiness.industryPostpartum PeriodParturitionSocial SupportObstetrics and GynecologyFearMaternal adjustmentChildbirth experienceDelivery ObstetricDelivery modemedicine.diseaseta3123Postnatal depressionPregnancy ComplicationsPsychiatry and Mental healthClinical PsychologyPost traumatic stress syndromeReproductive MedicineFear of childbirthEdinburgh Postnatal Depression ScalePsychotherapy GroupAnxietyFemalePregnant Womenmedicine.symptombusinessPsychosocialPostpartum periodJournal of Psychosomatic Obstetrics & Gynecology
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Health-related quality of life after camp-based family obesity treatment: an RCT.

2019

ObjectiveTo compare the effects of a 2-year camp-based immersion family treatment for obesity with an outpatient family-based treatment for obesity on health-related quality of life (HRQoL) in two generations.DesignRandomised controlled trial.SettingRehabilitation clinic, tertiary care hospital and primary care.PatientsFamilies with at least one child (7–12 years) and one parent, both with obesity.InterventionsSummer camp for 2 weeks, with four repetition weekends, or lifestyle school, including four outpatient days over 4 weeks. Behavioural techniques to promote a healthier lifestyle.Main outcome measuresChildren’s and parents’ HRQoL were assessed using generic and obesity-specific measure…

medicine.medical_specialtyobesitymedicine.medical_treatmentPsychological intervention030209 endocrinology & metabolismlaw.inventionrehabilitationTreatment and control groups03 medical and health sciences0302 clinical medicineRandomized controlled trialVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Pediatri: 760lawMedicine030212 general & internal medicine1506RehabilitationIntention-to-treat analysisbusiness.industrymedicine.diseasepatient perspectiveObesityPeer reviewPediatrics Perinatology and Child HealthPhysical therapyOriginal ArticlebusinessBody mass indexBMJ paediatrics open
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Palliative splenic irradiation in primary and post PV/ET myelofibrosis: outcomes and toxicity of three radiation schedules

2009

Splenectomy and splenic irradiation (SI) are the sole treatment modalities to control drug resistant splenomegaly in patients with myelofibrosis (MF). SI has been used in poor surgical candidates but optimal total dose and fractionation are unclear. We retrospectively reviewed 14 MF patients with symptomatic splenomegaly. Patients received a median of 10 fractions in two weeks. Fraction size ranged from 0.2–1.4 Gy, and total dose varied from 2–10.8 Gy per RT course. Overall results indicate that 81.8% of radiation courses achieved a significant spleen reduction. Splenic pain relief and gastrointestinal symptoms reduction were obtained in 94% and 91% of courses, respectively. Severe cytopeni…

medicine.medical_specialtypalliationmedicine.medical_treatmentSplenectomyMyelofibrosisSpleenSubgroup analysisGastroenterologyArticleInternal medicineMedicinemyelofibrosis; splenomegaly; palliation; radiotherapy; low-dose irradiationMyelofibrosisAdverse effectradiotherapylow dose irradiationsplenomegalylcsh:RC633-647.5business.industrylow-dose irradiation.lcsh:Diseases of the blood and blood-forming organsHematologymedicine.diseaseSurgeryRadiation therapymedicine.anatomical_structureTolerabilityToxicitybusinessHematology Reports
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Is telephone follow-up useful in preventing post-extraction bleeding in patients on antithrombotic treatment?

2021

Background The aim of the study was to investigate the usefulness of telephone follow-up in preventing post-extraction bleeding and improving wound healing in patients on chronic antithrombotic treatment. Material and methods A prospective randomized clinical trial was carried out on 256 patients (test group = 128; control group = 128). The exact two-tailed Fisher test and the two-tailed non-parametric Mann-Whitney test were used for statistical analysis. Results The incidence of post-extraction bleeding was 15.6% and there was no difference between test and control groups. However, the study group was significantly, though weakly, associated with the severity of bleeding. Patient satisfact…

medicine.medical_specialtypatient satisfactionTest groupbusiness.industryResearchIncidence (epidemiology)wound healingSurgical woundlaw.inventionSurgeryAntithrombotic treatmentsymbols.namesakePatient satisfactionRandomized controlled triallawmedicinesymbolsOdontostomatology for the Disabled or Special PatientsIn patientpost-operative instructionsbusinessGeneral DentistryUNESCO:CIENCIAS MÉDICASpatient satisfaction; post-operative instructions; wound healingFisher's exact testJournal of Clinical and Experimental Dentistry
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Repetition without Repetition or Differential Learning of Multiple Techniques in Volleyball?

2021

A variety of approaches have been proposed for teaching several volleyball techniques to beginners, ranging from general ball familiarization to model-oriented repetition to highly variable learning. This study compared the effects of acquiring three volleyball techniques in parallel with three approaches. Female secondary school students (N = 42

medicine.medical_specialtyskill acquisitionHealth Toxicology and MutagenesisArticleDreyfus model of skill acquisitionmedicineHumansLearningdifferential learningAdditional retentionMathematicsPhysical Education and Trainingoverhand passmultiple techniquesRepetition (rhetorical device)Significant differencePublic Health Environmental and Occupational HealthvolleyballRunderhand passTest (assessment)Motor SkillsDifferential learningPhysical therapyMedicineFemaleoverhand serviceLearning groupMotor learningmotor learningInternational Journal of Environmental Research and Public Health
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Individualized analysis of skin thermosensory thresholds and sensitivity in heat-sensitive people with multiple sclerosis

2020

We investigated whether and how multiple sclerosis (MS) alters thresholds for perceiving increases and decreases in local skin temperature, as well as the sensitivity to progressively greater temperature stimuli, amongst heat-sensitive people with MS. Eleven MS patients (5 M/6 F; 51.1 ± 8.6 y, EDSS 5.7 ± 1.9) and 11 healthy controls (CTR; 7 M/4 F; 50.3 ± 9.0 y) performed warm and cold threshold tests on a hairy skin site, on both sides of the body. They also underwent a thermosensitivity test where they rated (visual analogue scale) perceived magnitude of 4 local skin stimuli (i.e. 22, 26, 34, 38°C). Individual thresholds and slopes of linear regression for thermosensitivity were z-transfor…

medicine.medical_specialtyskinPhysiologybusiness.industryVisual analogue scaleHairy skinMultiple sclerosisbody Temperature Regulation Multiple Sclerosis skin thermoreceptorsSkin temperatureAudiologymedicine.diseasePriority ReportHeat stressHeat sensitivethermoreceptorPhysiology (medical)Multiple SclerosimedicineThermoreceptorPatient groupbusinessbody Temperature RegulationSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' Motorie
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Optimization of the Speech Test Material in a Group of Hearing Impaired Subjects: A Feasibility Study for Multilingual Digit Triplet Test Development

2021

Background: The development of the global digit-in-noise test requires optimization of each language version on a group of normal-hearing native-speakers. An alternative solution may be an adaptive optimization during ongoing tests in a group of subjects with unknown hearing impairments. The objective of the research was to compare the optimization results between these groups. Methods: Digit triplets consisting of three pseudo-randomly selected digits were presented in speech-shaped noise at various signal-to-noise ratios (SNRs), according to the protocol of the final speech test. Digit-specific and position-specific speech reception thresholds (SRTs) were determined and compared between g…

medicine.medical_specialtyspeech audiometry; speech intelligibility in noise; digit triplet test; digit-in-noise test; speech reception threshold; tele-audiology; mobile-based hearing testsdigit-in-noise testspeech audiometryAudiologyArticle03 medical and health sciences0302 clinical medicineTest materialotorhinolaryngologic diseasesmedicinemobile-based hearing tests030212 general & internal medicineSpeech reception030223 otorhinolaryngologydigit triplet testGroup (mathematics)tele-audiologyspeech reception thresholdNumerical digitTest (assessment)Continuous noiseNoiseRF1-547OtorhinolaryngologyHearing impairedspeech intelligibility in noisePsychologyAudiology Research
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