Search results for "holding"
showing 10 items of 123 documents
Predictors of survival in patients with advanced hepatocellular carcinoma who permanently discontinued sorafenib
2015
Treatment with sorafenib of patients with advanced hepatocellular carcinoma is challenged by anticipated discontinuation due to tumor progression, liver decompensation, or adverse effects. While postprogression survival is clearly determined by the pattern of tumor progression, understanding the factors that drive prognosis in patients who discontinued sorafenib for any reason may help to improve patient management and second-line trial design. Patients consecutively admitted to three referral centers who were receiving best supportive care following permanent discontinuation of sorafenib for any reason were included. Postsorafenib survival (PSS) was calculated from the last day of treatmen…
Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit
2018
PURPOSE: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU. METHODS: This prospective study included intensive care patients aged ≥ 80 years in 309 ICUs from 21 European countries with 30-day mortality follow-up. RESULTS: LST limitation was identified in 1356/5021 (27.2%) of patients: 15% had a withholding decision and 12.2% a withdrawal decision (including those with a previous withholding decision). Patients with LST limitation were older, more frail, more severely ill and less frequently electively admitted. Patients with withdrawal of LST were more frequently male and had a longer ICU len…
Fast recovery with etanercept in patients affected by polymyalgia rheumatica and decompensated diabetes: a case-series study
2008
We enrolled nine consecutive patients affected by newly diagnosed polymyalgia rheumatica and decompensated diabetes mellitus. All patients were treated with etanercept (25 mg twice weekly) and prednisone and were followed up to 1 year. At the sixth-month follow-up, etanercept and prednisone were withdrawn. Patients were seen at regular intervals (days 0, 30, 60, 90, 150, 180) and the following variables determined: erythrocytes sedimentation rate, C-reactive protein, fasting serum glucose, pain measured by visual analog scale, and the Health Assessment Questionnaire. Our results indicate that etanercept might have some steroid-sparing effects, but controlled investigations are needed to sup…
Effect of the height-to-diameter ratio on the mass transfer and mixing performance of a biotrickling filter
2017
BACKGROUND Biotrickling filters (BTFs) are among the most widely used biological technologies for air pollution control. The pollutant removal rate in BTFs relies to a large extent on its gas–liquid mass transfer performance. Therefore, knowledge of the design parameters affecting the mass transfer and mixing performance of full-scale BTFs is of paramount importance. RESULTS This work showed that the height-to-diameter (H/D) ratio is an important parameter in the design of BTFs devoted to air pollution control. The H/D ratio significantly affected the mass transfer and mixing performance of the BTF with and without additional stirring in the holding tank. It was observed that under the same…
On the packing–holding flow in the injection molding of thermoplastic polymers
1988
Injection molding tests were performed on a Ny66 resin. Data of mass entering the mold during the packing–holding stage as a function of filling flow rate and holding time are presented. The experimental results are discussed on the basis of a simple model of the packing–holding stage. Only a small part of density increase due to crystallization seams to be compensated by the packing–holding extra flow.
Effect of some injection molding processing conditions on weld lines characteristics
1988
The influence of injection and mold temperature as well as holding time on the knit-line characteristics in samples of Nylon 6 obtained by injection molding was analysed. The characteristics of the surface defect seem to be governed by the shrinkage rate and amount in the weld line zone.
Computer vision profilometer: equipment and evaluation of measurements
1991
Abstract This paper describes a new equipment that measures roughness values by a computer vision (CV) technique. Measurements carried out by a CV profilometer are also evaluated. A laser source (power 2 mW), a cylindrical lens and a charge coupled device (CCD) TV-camera with a suitable optical system form an image of the profile of the sample under inspection. This image is then transformed into a binary image by thresholding and the line that divides the bright zone from the dark zone is the sample profile. From this line the characteristic roughness values can be calculated. The roughness measurements are carried out both by the CV profilometer and a stylus profilometer on eight specimen…
Combined K-Best sphere decoder based on the channel matrix condition number
2008
It is known that sphere decoding (SD) methods can provide maximum-likelihood (ML) detection over Gaussian MIMO channels with lower complexity than the exhaustive search. Channel matrix condition number represents an important influence on the performance of usual detectors. Throughout this paper, two particular cases of a SD method called K-Best carry out a combined detection in order to reduce the computational complexity with predictable performance degradation. Algorithm selection is based on channel matrix condition number thresholding. K-Best is a suboptimal SD algorithm for finding the ML solution of a detection problem. It is based on a fixed complexity tree search, set by a paramete…
General Economic Order Quantity Model for Lot Sizing with Quality Loss and Process Analysis
1995
In this paper a new model GEOQ is proposed to decide the optimal lot sizing in production. The GEOQ modifies the classical EOQ method in several aspects. First it considers that there is always a probability that the production goes out-of-control; then it takes the time the process goes out-of-control as a stochastic quantity; and finally it adds quality loss to the economic models. The quality loss is calculated according to Taguchi’s quadratic loss function. and depends on the process failure models. Therefore, the optimal lot sizing is decided not only by the set-up cost and the holding cost but also by the quality loss during the manufacturing process.
Signal Restoration via a Splitting Approach
2012
International audience; In the present study, a novel signal restoration method from noisy data samples is presented and is termed as "signal split (SSplit)" approach. The new method utilizes Stein unbiased risk estimate estimator to split the signal, the Lipschitz exponents to identify noise elements and a heuristic approach for the signal reconstruction. However, unlike many noise removal techniques, the present method works only in the non-orthogonal domain. Signal restoration was performed on each individual part by finding the best compromise between the data samples and the smoothing criteria. Statistical results are quite promising and suggest better performance than the conventional…