Search results for "host-guest complexes"

showing 8 items of 18 documents

Binding equilibria between beta-cyclodextrin and p-nitro-aniline derivatives: the first systematic study in mixed water-methanol solvent systems.

2009

Abstract Complexation equilibria, in mixed water–methanol solvent media, between native β-cyclodextrin and a set of suitably selected p -nitro-aniline derivatives were studied by means of polarimetry. The effects exerted by the organic co-solvent on the conditional inclusion free energies Δ G cond 0 and the differential molar optical rotations Δ Θ were thoroughly analyzed under the perspective of the enthalpy–entropy compensation effect. Experimental data suggest an intimate participation (‘dynamic co-inclusion’) of solvent molecules in the formation and in the conformational dynamics of the host–guest inclusion complex.

chemistry.chemical_classificationCyclodextrinOrganic ChemistryEnthalpyNitro compoundSettore CHIM/06 - Chimica OrganicaBiochemistryCyclodextrin host-guest complexes polarimetryInclusion compoundSolventchemistry.chemical_compoundAnilinechemistryComputational chemistryDrug DiscoveryNitroMoleculeOrganic chemistry
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Binding properties of mono-(6-deoxy-6-amino)-β-cyclodextrin towards p-nitroaniline derivatives: a polarimetric study

2009

Abstract Polarimetry was used in order to investigate the formation of supramolecular complexes between mono-6-amino-β-cyclodextrin and various p-nitroaniline derivatives at two different pH values. Comparison with the behaviour of native β-cyclodextrin gave us the opportunity to consider the effect exerted by the presence of charged groups, having different solvation requirements, on the binding equilibrium. Data offer some support to the hypothesis of ‘dynamic co-inclusion’ of solvent molecules within the host–guest complex.

chemistry.chemical_classificationCyclodextrinStereochemistryOrganic ChemistrySupramolecular chemistrySolvationNitro compoundcyclodextrins polarimetric study host-guest complexes stability constantsSettore CHIM/06 - Chimica OrganicaBiochemistryInclusion compoundSolventchemistry.chemical_compoundchemistryDrug DiscoveryMoleculeAmine gas treatingTetrahedron
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Recognition of N-Alkyl- and N-Aryl-Acetamides by N-Alkyl Ammonium Resorcinarene Chlorides

2014

N-alkyl ammonium resorcinarene chlorides are stabilized by an intricate array of intra- and intermolecular hydrogen bonds that leads to cavitand-like structures. Depending on the upper-rim substituents, self-inclusion was observed in solution and in the solid state. The self-inclusion can be disrupted at higher temperatures, whereas in the presence of small guests the self-included dimers spontaneously reorganize to 1:1 host-guest complexes. These host compounds show an interesting ability to bind a series of N-alkyl acetamide guests through intermolecular hydrogen bonds involving the carbonyl oxygen (C=O) atoms and the amide (NH) groups of the guests, the chloride anions (Cl(-)) and ammoni…

chemistry.chemical_classificationHydrogen bondStereochemistryArylOrganic ChemistryIntermolecular forceGeneral Chemistrymacromolecular substancesResorcinareneMedicinal chemistryCatalysischemistry.chemical_compoundchemistryAmideAmmoniumresorcinarenes; NMR titration; amides; host-guest complexes; X-ray crystallographyta116AlkylAcetamide
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Enantioselective recognition of alfa-amino acids by binary complexes fluorophore/cyclodextrin

cyclodextrin chiral recognition host-guest complexesSettore CHIM/06 - Chimica Organica
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Binary complexes heptakis-(6-amino)-(6-deoxy)-beta-cyclodextrin/fluorophore: structural investigation and chiral recognition

cyclodextrin host-guest complexes chiral recognitionSettore CHIM/06 - Chimica Organica
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Complexation equilibria between beta-cyclodextrin and p-nitroaniline derivatives in mixed solvent media: a polarimetric study

cyclodextrin host-guest complexes polarimetrySettore CHIM/06 - Chimica Organica
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Binding porperties of hetpakis-(2,6-di-O-methyl)-beta-cyclodextrin and mono-(3,6-anydro)-beta-cyclodextrin

cyclodextrins polarimetry host-guest complexes
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Host-guest interactions between DMpillar[5]arene and fluorescent imidazolium salts

pillar[n]arenes imidazolium salts host-guest complexesSettore CHIM/06 - Chimica Organica
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